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Isolated Right Coronary Ostial Stenosis Due to Syphilitic Aortitis
정청일,김경수,이항락,이상,손병관,이숙진,강문수,이준수,이재웅,김순길,김정현,임헌길,이방헌,이정균 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2
정상 관상동맥 소견을 보이며 관상동맥구에만 국한되어 협착이 있는 소견은 매독성 대동맥염의 드문 합병증으로 되어 있으며 대부분의 경우가 부검시 발견된다. 저자들은 매독성 대동맥염의 증상으로 대동맥역류와 동반한 우관상동맥구에 국한된 협착을 보이는 59세 남자 환자를 경험하였고 관상동맥우회술을 시행하였다. 관상동맥질환에 대한 다른 위험인자는 없었으며 관상동맥조영술상 우관상동맥구의 협착을 제외하고는 정상소견을 보이고 있었다. 중요한 점은 매독이 관상동맥질환의 또 하나의 원인이 될 수 있다는 것이다. 저자들은 매독성 대동맥염의 합병증에 의한 우측관상동맥구의 협착으로 생각하고 있으며, 매독과 연관된 우측관상동맥구의 협착 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
정상완,유인설,김진현,강성욱,권미혜,정청일,최인아,장성혜,강미일,홍승재,이연아 연세대학교의과대학 2021 Yonsei medical journal Vol.62 No.5
Purpose: To investigate correlations between myositis-specific autoantibodies (MSA) or myositis-associated antibodies (MAA) andclinical features, thereby demonstrating the utility of clinicoserologic classification in idiopathic inflammatory myopathies (IIM) patients. Materials and Methods: We conducted a multicenter study of 108 adult patients (age ≥18 years) who were diagnosed with IIM byPeter and Bohan criteria or 2004 European Neuromuscular Centre (ENMC) criteria. Clinical data were obtained by medical recordreview. Immunoblot assay with Euroline strip (EUROIMMUN, Germany) was performed using the sera of dermatomyositis (DM,n=56), polymyositis (PM, n=45), amyopathic DM (n=5), DM sine dermatitis (n=1), and immune mediated necrotizing myopathy(n=1) patients. Patients were classified based on two classifications: 2017 EULAR/ACR and novel clinicoserologic classification. Results: According to 2017 EULAR/ACR criteria, DM and PM were the most and the second most frequent entities. Overlap myositiswas the major entity of IIM, and the frequency of PM was significantly lower when applying clinicoserologic classification criteria. Sixty-nine (63.9%) patients had one or more MSA, and 61 (56.5%) patients had one or more MAA. Interstitial lung disease wasclosely associated with anti-MDA5 and anti-ARS, and DM-specific skin lesions were frequently observed in patients with anti-TIF1γ, anti-SRP, and anti-MDA5. Conclusion: The clinicoserologic criteria based on MSA/MAA positivity could reflect more precise clinical features of IIM. Establishmentof a laboratory system routinely available to screen for MSA/MAA status will be beneficial to provide precise diagnosisand proper management of IIM patients.
정청일 ( Chung Il Joung ) 대한류마티스학회 2013 대한류마티스학회지 Vol.20 No.4
Infection is a critical and challenging situation encountered in treatment of inflammatory rheumatic diseases (IRDs). It is associated with the disease activity itself and/or the immunosuppressant treatments. Vaccine preventable infections could be controlled by use of a timely vaccination protocol. Immunosuppressed situations observed in IRDs require some modification of the recommendation for the general population in each national society. Live attenuated vaccines are generally contraindicated in IRDs, except for varicella-zoster vaccination, which is solely permitted live vaccine and could be given on a case by case basis in autoimmune IRDs. Influenza and pneumococcal vaccines are strongly recommended due to increased mortality in patients with IRDs. The vaccination protocol reflects the current national medical environment and requirements; therefore, it could change with time. The Korean Rheumatology Society now requires that vaccination be recommended for patients with IRDs, with the possibility of both an adult and child version.