생명장의학과 한울기공

정윤숙 한국정신과학학회 2001 한국정신과학회 학술대회 논문집 Vol.15 No.-

모든 생명체는 탄성을 지닌 큰 비눗방울과 같은 생명장이라는 캡슐 속에 들어 있는 것과 같다. 그 캡슐들이 서로 이합 집산하면서 더 큰 생명장을 이루어 엄청난 에너지원이 되기도 하고, 때로는 서로 충돌하여 기를 소모하고 캡슐 속의 생명체에게 충격을 가하여 상하게 하기도 한다. 그 캡슐 내부를 구성하는 매질의 성질에 따라 충격이 강하게, 순하게, 빠르게, 느리게 전하여짐으로써 몇 개의 생명장으로 대별할 수 있으며, 그것의 특성에 따라 병의 발생이나 치유의 방법이 달라진다 서로 충돌하여 공이 튀듯이 다른 생명장과 충돌하고 연쇄반응이 사회적 현상으로 드러나기도 한다. 생명장은 어느 정도 수련을 한 사람이면 누구나 감지 할 수 있으며, 수련 정도에 따라 진단이나 치료가 달라진다. 생명장은 생명체에 형성된 기의 장으로서 생명장이 외부 또는 내부의 압력에 의해 일그러지면 질병이 발생한다. 생명장 수련을 한 사람은 누구나가 이를 감지할 수 있다 생명장에서는 질병의 원인을 보다 근본적인데 두고 있으며, 그 원인을 크게 세 가지인 영기, 몸기, 지기로 분류한다. 영기는 영적인 부분을 말하는 것이고, 몸기는 육체적인 부분을, 지기는 우리가 살고 있는 터전과 관련된 원인을 말한다. 병의 원인이 영기, 몸기, 지기라 하더라도 세부적으로 들어가면 질병의 원인이 다양하다.

소아암 환아에서의 Varicella zoster 바이러스 감염 유형과 인자 및 치료에 관한 임상적 연구

정윤숙,김수현,김기중,이항 대한소아청소년과학회 2001 Clinical and Experimental Pediatrics (CEP) Vol.44 No.11

노인의 영양상태에 영향을 미치는 구강건강 요인

정윤숙 한국치위생학회 2018 한국치위생학회지 Vol.18 No.6

Objectives: The study aimed to identify the oral health factors that affect the nutritional status of the elderly. Methods: The study was conducted over ten months from September 2013 to June 2014, and included senior citizens who were supported by the visiting health service. The rate of saliva release, the number of remaining teeth, and the ability of the elderly to identify nutritional conditions were evaluated. Statistical analyses were performed using the t-test, ANOVA, and multiple linear regression using SAS 9.4 (SAS Institute Inc., Cary, NC, USA.). Results: The study participants had an average irritation saliva secretion rate of 2.26 ± 1.11 mg per minute. The higher the rate of saliva secretion, the higher the mini nutritional assessment (MNA) score (p<0.001). The average number of remaining teeth was 8.21 ± 9.76. The MNA scores were highest in groups with 11 or more remaining teeth (p=0.001). The factors that affected the nutritional condition of the elderly were their ability to perform activities of daily living, saliva flow rate, and number of remaining teeth. The highest correlation among them was that of the standardized regression coefficient was – 0.386 by activity daily living , followed by a 0.170 saliva secretion rate and 0.118 remaining teeth in daily life performance. Conclusions: Activities of daily living and rate of saliva secretion showed the highest correlations to nutritional status of the elderly.

숙성조건이 마늘의 품질특성에 미치는 영향

정윤숙,황경아,김가람,송진,노건민,황인국,Jeong, Yun Sook,Hwang, Kyung-A,Kim, Ga Ram,Song, Jin,Noh, Geon Min,Hwang, In Guk 한국식품영양학회 2015 韓國食品營養學會誌 Vol.28 No.5

본 연구에서는 숙성 온도와 기간에 따른 마늘의 품질특성변화를 살펴보기 위하여 통마늘을 $60^{\circ}C$에서 60일간, $70^{\circ}C$에서 40일간 숙성 처리하여 pH, 총산도, 갈변도, 5-HMF 함량, fructose 함량, SAC 함량, 총 폴리페놀 함량 및 DPPH radical 소거활성 측정하였다. 숙성 온도가 높고 숙성 기간이 길어질수록 마늘의 pH는 감소하고, 총 산도, 갈변도 및 5-HMF 함량은 증가하는 경향을 보였다. 특히, 5-HMF 함량은 $60^{\circ}C$ 숙성 처리 시 0.08~3.30 mg/100 g으로 증가량이 적은 반면, $70^{\circ}C$ 숙성 처리 시 0.05~106.07 mg/100 g으로 숙성 25일차부터 급격히 증가하는 것으로 나타났다. Fructose 함량은 $60^{\circ}C$의 숙성온도에서는 0.77~14.57%으로 지속적으로 증가한 반면, $70^{\circ}C$ 숙성 온도에서는 30일차까지 1.07~19.75%까지 증가 후 15.11%로 감소하는 것으로 나타났다. SAC 함량은 생마늘의 경우 48.11 mg/100 g이었으며, $60^{\circ}C$에서 20일 숙성 시 100.50 mg/100 g으로, $70^{\circ}C$에서 5일 숙성 시 85.55 mg/100 g까지 증가한 후 숙성 기간이 경과할수록 SAC 함량은 감소하였다. 생마늘의 총 폴리페놀 함량은 98.38 mg/100 g이었고, $60^{\circ}C$ 숙성 처리 시 591.82 mg/100 g까지, $70^{\circ}C$ 숙성 처리 시에는 665.22 mg/100 g까지 생마늘에 비해 각각 6.01배 및 6.67배 증가하였다. DPPH radical 소거활성의 경우, 숙성 온도가 높고 숙성 기간이 길어질수록 증가하는 경향을 보였다. 따라서 마늘 섭취가 용이하고 항산화 활성이 우수한 숙성 마늘 제조를 위해서는 $70^{\circ}C$에서 30일, 숙성 마늘의 유효성분인 SAC의 다량 생산을 위해서는 $60^{\circ}C$에서 15일간 숙성 처리하는 하는 것이 적합할 것으로 판단되며, 이상의 결과는 항산화 효과가 강화 및 SAC 함량 증진 등 선택적인 숙성 마늘의 제조에 활용이 가능할 것으로 기대된다. This study was performed to investigate the quality characteristics such as pH, total acidity, browning index, 5-hydroxymethylfurfural (5-HMF), fructose, S-allyl-L-cysteine (SAC), total polyphenol, and DPPH radical scavenging activity of aged garlic at different aging temperatures and periods. Aging temperature and period had a significant (p<0.05) effect on the quality characteristics of garlic. The pH in aged garlic significantly (p<0.05) decreased with increasing aging temperatures and periods, while the total acidity, browning index, and 5-HMF levels increased. The 5-HMF levels in garlic aged at 60 and $70^{\circ}C$ increased from 0.08~3.30 and from 0.05~106.07 mg/100 g, respectively. The fructose content in garlic aged at $60^{\circ}C$ gradually increased from 0.77 to 14.57%, while that of garlic aged at $70^{\circ}C$ increased from 1.07 to 19.75% until day 30, after which it decreased. The SAC level in raw garlic was 47.09 mg/100 g. The SAC contents of aged garlic differed significantly according to aging temperature and period. The SAC levels in garlic aged at $60^{\circ}C$ and $70^{\circ}C$ were in the range of 15.28~100.5 and 12.41~85.55 mg/100 g, respectively. The total polyphenol contents of garlic aged at $60^{\circ}C$ and $70^{\circ}C$ were 6.01 and 6.67 fold higher, respectively, than those in raw garlic. The DPPH radical scavenging activity of aged garlic also showed a tendency to increase during aging.

국내산 여주의 지역별, 수확시기별, 숙기별 Vitamin C 함량

정윤숙,이상훈,송진,황경아,노건민,황인국,Jeong, Yun Sook,Lee, Sang Hoon,Song, Jin,Hwang, Kyung-A,Noh, Geon Min,Hwang, In Guk 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.4

본 연구에서는 vitamin C 분석법을 검증하고, 국내산 지역별 여주와 재배 시기별, 숙기별 여주의 vitamin C 함량을 분석하였다. Vitamin C 분석법을 검증하기 위해 직선성, 검출한계, 정량한계, 정밀성 및 정확성을 확인하였고, 그 결과 직선성의 상관계수 값은 0.9994, 검출한계는 $0.05{\mu}g/mL$, 정량한계는 $0.16{\mu}g/mL$, 정밀성의 상대표준편차는 intra-day test에서는 2.34 %, inter-day test에서는 1.34%이었고, 정확성인 회수율은 98.66~101.74%로 95% 이상의 높은 회수율을 보였다. 여주는 지역별로 vitamin C를 분석한 결과 20.75~107.31 mg/100 g, FW로 함량 차이가 높았으며, 평균 함량은 $68.85{\pm}25.57mg/100g$, FW로 나타났다. 평균 함량을 기준으로 구분하였을 때, 전라북도 지역에서 재배한 여주는 평균보다 낮은 함량을 보였고, 전라남도 지역에서 재배한 여주는 영암을 제외하고 모두 평균보다 높은 함량을 보였다. 수확시기별 여주의 vitamin C의 함량은 재배 초기 6월까지 vitamin C의 함량이 $113.20{\pm}1.89mg/100g$, FW로 증가하였다가 점차 감소하는 경향을 보였다. 또한 숙기별 vitamin C의 함량은 성장 초기에는 vitamin C의 함량이 0.53~0.68 mg/100 g, FW로 낮은 수준이었지만 숙기 15일차에서는 vitamin C의 함량이 $48.59{\pm}0.87mg/100g$, FW까지 증가하였다가 점차 감소하는 것을 확인하였다. 이처럼 여주의 vitamin C 함량은 지역별 생육환경에 따라, 재배 시기별, 숙기별에 따라 함량 차이가 나타났으며, 기능성 식품원료의 개발과 추후 연구의 기초자료로 활용이 가능할 것으로 기대된다. This study aimed to investigate the concentration of vitamin C in Momordica charantia (MC) by cultivar, harvest time, and maturity. The methods for determining vitamin C levels were validated by measuring their linearity, specificity, limit of detection (LOD), limit of quantification (LOQ), precision, and accuracy using HPLC. Results showed high linearity in the calibration curve, with a coefficient of correlation ($R^2$) of 0.9994. The LOD and LOQ values for vitamin C were 0.05 and $0.16{\mu}g/mL$, respectively. The relative standard deviations (RSDs) for intra- and inter-day precision of vitamin C measurements were 2.34 and 1.34%, respectively. Depending on cultivar, the concentration of vitamin C in MC varied from 20.75~107.31 mg/100 g, fresh weight, with an average level $68.85{\pm}25.57mg/100g$, FW. When MC was analyzed by harvest time, the 20150612 MC showed the highest amount of vitamin C ($113.20{\pm}1.89mg/100g$, FW). On the other hand, the highest vitamin C content by maturity was $48.59{\pm}0.87mg/100g$, FW (15 day old MC). This information on the comparative vitamin C levels of MC might be useful to food scientists and should be explored for functional food development.

환경변화에 따른 주유소의 나아갈 방향

정윤숙,Jeong, Yun-Suk 대한석유협회 1991 석유와 에너지 Vol.1991 No.7

중금속의 혈중 농도와 치주염간의 상관성에 대한 연구 : 제5기 국민건강영양조사 자료 이용

정윤숙,김은경 한국치위생학회 2019 한국치위생학회지 Vol.19 No.4

Objectives: Internal exposure to certain heavy metals is thought to be associated with periodontitis. Therefore, this study aimed to assess the relationship between blood levels of heavy metals and periodontitis among the Korean population. Methods: Data from the 2012 Korean National Health and Nutrition Examination Survey was analyzed. A total of 1,968 adults aged 19 years or above were included. Logistic regression analysis was performed to assess the association between blood lead levels of lead, cadmium, and mercury, and periodontitis. Confounders such as sex, age, brushing frequency, smoking, etc. were adjusted. Results: Blood levels of lead, cadmium, and mercury showed a significant relationship with periodontitis in a crude model of logistic regression analysis. However, participants with the highest blood levels of cadmium showed higher risk of periodontitis, than those with lower blood levels of cadmium (OR: 1.73; 95% CI: 1.11-2.70) after adjusting for the confounders. Conclusions: High blood levels of cadmium may be associated with periodontitis among the Korean population.

Changes in Abdominal Obesity Affect the Risk of Metachronous Advanced Colorectal Neoplasia Development after Polypectomy

정윤숙,김남희,박정호,박동일,손정일 연세대학교의과대학 2020 Yonsei medical journal Vol.61 No.7

Purpose: The impact of changes in body mass index and waist circumference on the development of metachronous colorectal neoplasia (CRN) after polypectomy has rarely been examined. We evaluated the association between changes in overall/abdominal obesity and metachronous CRN risk. Materials and Methods: We studied patients who underwent ≥1 adenoma removal and surveillance colonoscopy. Patients were classified into the following four groups based on the changes in overall obesity from index to follow-up colonoscopy: non-obesity persisted (group 1), obesity to non-obesity (group 2), non-obesity to obesity (group 3), and obesity persisted (group 4). Patients were also divided into another four groups based on similar changes in abdominal obesity (groups 5–8). Results: The number of patients in groups 1, 2, 3, and 4 was 5074, 457, 643, and 3538, respectively, and that in groups 5, 6, 7, and 8 was 4229, 538, 656, and 2189, respectively. Group 4 had a significantly higher risk of metachronous CRN compared to groups 1 and 2. However, metachronous advanced CRN (ACRN) risk was not different among groups 1, 2, 3, and 4. Metachronous CRN risk in group 8 (abdominal obesity persisted) was higher than that in groups 5 (non-abdominal obesity persisted) and 7 (non-abdominal obesity to abdominal obesity), and tended to be higher than that in group 6 (abdominal obesity to non-abdominal obesity). Additionally, group 8 had a significantly higher risk of metachronous ACRN compared to groups 5, 6, and 7. Conclusion: Changes in obesity affected the metachronous CRN risk. In particular, changes in abdominal obesity affected the metachronous ACRN risk.

Oral Health Status and Oral Health-related Quality of Life According to Presence or Absence of Mucositis in Head and Neck Cancer Patients

정윤숙,박은영,손해옥 대한암예방학회 2019 Journal of cancer prevention Vol.24 No.1

Background: Oral mucositis during radiotherapy which is harmful to the patients with head and neck is suggested to be related to the oral hygiene and health. Therefore, we evaluated the oral health status in relation to the occurrence of mucositis among patients with head and neck cancer during radiotherapy. Methods: Tooth plaque index (PI), periodontal depth, and oral mucositis in 50 patients with head and neck cancer were examined by a dentist for 8 weeks after radiotherapy initiation. Cancer type and site were recorded based on the patients’ medical records. In addition, we assessed oral health-related quality of life. Results: The mean age of participants was 56.3 ± 11.6 years, with patients aged > 60 years comprising the largest proportion of the mucositis group. The median (range) of the PI index were 0 (0-3) and 1 (0-3) among participants with mucositis and those without, respectively, with no significant difference (P = 0.761). The median (range) of the total Oral Health Impact Profile score were 54 (42-58) and 41 (14-70) among participants without mucositis and those with mucositis, respectively (P = 0.037). Conclusions: This study showed that patients who developed mucositis during radiotherapy had lower oral health-related quality of life than those who did not. However, there was no difference in oral health status according to mucositis. (J Cancer Prev 2019;24:43-47)

들·물·노동이 직조(직조)한 삶과 역사를 만나다

정윤숙 열린전북 2008 열린전북 Vol.2008 No.6