L-Tryptophan투여에 의한 간내 Triglyceride 축적에 대한 실험적 연구

정남수,김제현,송정적 최신의학사 1971 最新醫學 Vol.14 No.9

In 1971 Kim observed that the injection of excess dose of tryptophan produced the accumulation of hepatic triglyceride and also reported that the mechanism was involved in fatty acid or triglyceride syn?thesis but not oxidation of fatty acid by using of labeled compound, palmitate-1-014 and acetate-1-C" We report our investigation of a minimum amount of tryptophan to produce hepatic triglyceride accu?mulation and a mechanism in vivo and in vitro experiments(in liver slice and in the isolated perfused liver). Male albino rats weighing 200-250g, prior to the experiments have been fed a diet 15% casein for one week. L-Tryptophan of 0.34, 0. 1, 0.05, 0.025, and 0.001 mmole and several metabolites of tryptophan of 0. 34 m mole per rat have been injected intraperitoneally into the intact rats. Six hours later the rats have been sacrificed, and the concentration of hepatic triglyceride has been determined. And lipolysis experiments by tryptophan in epidydimal adipose tissue was performed, and also triglyceride accumulation in the isolated perfused liver was studied. Results as follows 1. In vivo. a) An injection of 0. 34, 0. 1," 0.05, 0. 025, and 0.001mmole of tryptophan per each rat produced hepatic triglyceride accumulation of 21.80±0.87, 19.96±2.53, 16.67±1.12, 11.19±1. 10 and 10.64±0.54mg in each g of liver. b) The minimum amounts of tryptophan to produce hepatic triglyceride accumulation was 0.05mmole per each rat. c) An injection of kynurenine, 3-hydroxyanthranilic acid, nicotinic acid, or nicotinamide produced hepatic triglyceride accumulation of 13.21, 11.13± 0.54, 7.5±0.24, and 9.47±0.96mg per each g of liver, and these values were lower than 21.8±0.87 mg of tryptophan treated, and similar or lower than 12.8±1.10 mg of control. d) Hepatic triglyceride accumulation was not produced by the tryptophan metabolites such as kynure- nine, 3-hydroxyanthranilic acid, nicotinic acid, or nicotinamide. e) An injection of 11.2? mole sod. citrate had no effect on hepatic triglyceride accumulation. 2. In Vitro a) In Warburg's vessels, tryptophan had no effect on lipolysis in rat epidydirnal adipose tissue. b) In perfusion system, i) In 0, 2. 5, 4, and 5 hours following the infusion of tryptophan hepatic triglyceride contents were shown as 10.66±1.6, 13.6, 20.34, 25.2, and 21.7mg per g of liver. ii) With infusion at the rate of 1.26ml (2.02mg of tryptophan) per each hour, the amino acid preparation which contained 1, 600 mg of tryptophan per liter did not accumulate hepatic tirglyceride.

제2부 8. 지역적 특성을 고려한 농촌주택 노후화 판단 모형의 개발

정남수,조순재,이정재,김한중 ( Nam Soo Jeong,Soon Jae Cho,Jeong Jae Lee,Han Jeong Kim ) 한국농촌계획학회 1998 `98 정기총회 및 춘계 학술논문발표회 Vol.- No.-

뉴노멀 시대 농업·농촌 정보화의 방향

정남수 한국농공학회 2022 韓國農工學會誌 : 전원과 자원 Vol.64 No.3

퇴행성 및 협부형 척추 전방전위증의 치료

정남수,전창훈 대한척추외과학회 2009 대한척추외과학회지 Vol.16 No.3

The etiology of spondylolisthesis, which determines the pathoanatomy and natural course, includes the abnormal development of lumbosacrum and various acquired conditions. Many patients with symptomatic degenerative and isthmic spondylolisthesis respond to non-surgical treatments, such as modification of their daily activity, medication, physical therapy and nerve block. Surgical treatment is indicated for intractable pain, neurological symptoms and the progression of slip. The natural course and patient’s demographics are also considered. Decompression of the neural stenosis and the fusion of segmental instability are the main surgical treatments of degenerative and isthmic spondylolisthesis Fusion and instrumentation should be chosen carefully for degenerative spondylolisthesis if it is stable. However, solid fusion is the most important procedure for isthmic spondylolisthesis. Anterior lumbar interbody fusion is an effective treatment regarding an anatomical restoration of slip, decompression of neural structures and optimal fusion for degenerative and isthmic spondylolisthesis.

Development of a Sustainable Regional Economic Growth Model (SREG) Using Multiplier Theory

정남수,Jung, Nam-Su The Korean Society of Agricultural Engineers 2007 한국농공학회논문집 Vol.49 No.1

This paper develops a Sustainable Regional Economic Growth Model (SREG) which estimates the relation of labor population change and employment increase in each occupation and maximum limits and minimum requirements of employment increase by labor population change in a specified region using multiplier theory. To develop the proposed model, sustainable regional economic growth is defined as a steady increase of labor population over a long term period and the limit of employment increase is defined as the estimated labor population change in the region with no need for commutation from the surrounded areas. Developed model was applied to 67 county in Pennsylvania State and the results revealed that the investment in infrastructure occupations, such as transportation, warehousing, utilities, information, communication, and other public utilities, maximizes the effects for increasing employment, whereas finance, insurance, and real estate occupations have minimum effects for increasing employment. Calculated minimum requirements of occupations show that infra-structure occupations is a critical factor for labor population change and maximum limits of occupations show that agriculture and finance occupations are difficult to increase independently.

비정형 자료의 정량화를 위한 정보계측 기법의 개발

정남수,이정재,김한중,허유만 한국농업정보과학회 2003 농업정보과학 Vol.4 No.1

Statistical total information was suggested by modifying Gell-Mann's total information in the process of dividing by bit number of composing elements. Results of application satisfied set condition of information suggested by Gell-Mann, converged in the case that all elements are known, and expressed the differences with deterministic information. To find the relation with real value, total information gathered in Encyclopedia regressed with land value and showed significant relation. Further research on automatic gathering information in more stable IGUS like internet would benefit assessing ambiguous value like environment and human feeling.

요추 유합술 후 인접 분절 추간판의 퇴행성 변화에 대한 자기공명영상 추시

정남수,전창훈,정구영,박정욱 대한척추외과학회 2008 대한척추외과학회지 Vol.15 No.2

Study Design:Retrospective case-control studyObjective:To use MRI to assess intervertebral disc degeneration at adjacent levels after spinal fusion and after discectomy.Summary ofLiterature Review:Degeneration of adjacent intervertebral discs following lumbar spinal fusion is one of the prin-cipal reasons for considering motion preservation techniques, such as placement of an artificial disc. Much attention has recentlybeen directed toward disc morphometric studies using MRI.Materials and Methods:Fifty-six patients who underwent spinal surgery for lumbar degenerative disease and who underwenta minimum of 2 years of follow-up MRIs were included in this study. Thirty-four patients were included in the lumbar fusionstudy group, and 22 patients were included in the discectomy control group. The MRI Thompson classification was used tograde both upper and lower adjacent disc degeneration preoperatively and at the time of last follow-up. Results:There were significant changes in Thompson degenerative grade in the upper adjacent levels for both the fusion grouppatients and in the discectomy group patients. However, there was no statistically significant difference between the two groupswith regard to either the upper or lower adjacent levels (p=0.146 and 0.350, respectively). Conclusions:In this short-term study comparing MRI outcomes in spinal fusion and discectomy patients, no significant differ-ence in adjacent disc degeneration was observed between the two group.

야곱 뵈메의 『그리스도에 이르는 길』(1624)에 대한 예비지식 : John Joseph Stoudt 英譯本의 서론

정남수 그리스도신학대학교 출판부 2009 교수논문집 Vol.9 No.-

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야코프 뵈메에 대하여 : 『 그리스도에 이르는 길』(1624)을 중심으로

정남수 그리스도신학대학교 출판부 2010 교수논문집 Vol.10 No.-

“Of Jacob Boehme’s The Way to Christ”for Today The end of this article is to introduce Jacob Boehme’s The Way to Christ to Korean scholarship and to get his insights in this work and his another works. Jacob Boehme(1575-1624), the German religious mystic of the late sixteenth and early seventeenth centuries, had an astounding influence on the history of Western philosophy (Stoudt, Jacob Boehme). Although there are a lot of Jacob Boehme’s works (e.g., Aurora) in the Western theological circle, yet we have no any articles or books in Korean theology. I know Jacob Boehme has lot of good effects on Western Christian mysticism, philosophy, literature, psychology, existentialism, and Isaac Newton. Yet because of Boehme’s special thoughts and works, he has been known as an outsider or a Christian heresy through Lutheran church. The Way to Christ is his representative book, including his major thoughts. In this paper I explore Boehme’s basic ideas in his The Way to Christ and try to reflect his oncepts to today’s theology. He oddly get special experience many times. It is called as“ illumination.”Yet Boehme says it as the Holy Spirit’s work. Futhermore his first illuminative experience in 1589, is most important to understand his ideas and works. He meets a stranger at shoeshop. At that time he is fourteen. Here he is ordered to be a good lad; “fear God, and reverence His Word.”So he is very delight to read the Holy Scriptures every day and night. And he begin his journeyman travels in 1592. After that, he could see the visible in invisible and the invisible in visible realty. He has special ability to see a depth of Ungrund (ground) and to express it by various terms. Specially Boehme sees good and evil, Yes and No, in all things. It says that there is evil in good. Therefore his mystical knowledge embraces a dialectic. Through his insights I could reflect on my faith and life. I would like to urge my readers first see Dr. John Joseph Stoudt’s Introduction to The Way to Christ before reading Boehme’s books. The Way to Christ (1947) consists of seven tracks (or Ways): (1) On June 1, 1622, Boehme begins to write Of True Repentance. This is his first fine track. In this writing he sees the worlds’Yes and No within his own being, and resolution of his conflict. (2) On 1622 Of True Resignation is written. This is his second track. Boehme here shows the same “learned ignorance”as found in Nicolas of Cusa(see, Stoudt, Jacob Boehme, p. 153), an attack upon the elevated human will, selfhood’s rational life. (3) On June 24, 1622, Boehme completes Of Regeneration or Of the New Birth. This tract has eight chapters. He makes to see the beginning of the way to Christ. (4) On the same year 1622, he writes his next tract, Of the Supersensual Life as a dialogue between a master and a disciple. It traces the course of the conflict in the soul. (5) On 1624, Boehme completes Of Dialogue between Enlighten man and Unenlighten man. This tract is his fifth writing. Here the enlighten man leads unenlighten man (or ego-centric reason) to Sophia. (6) Near the end of 1622 Boehme begins Of Divine Contemplation. I think this tract is very difficult for us. Yet there are Boehme’s main ideas in this work. Although The Way to Christ translated by Stoudt contains (7) Of Divine Prayer, I skip to this seventh tract in Korean version.

지역특성을 고려한 추사김정희문화상품화사업 사례분석

정남수,윤혜려 한국콘텐츠학회 2019 한국콘텐츠학회논문지 Vol.19 No.4

지역 경제 활성화를 위해 과거와 같은 대규모 산업화보다는 각 지역에 전래해 온 고유문화와 기술, 특정지역에 뿌리를 두고 지역주민의 삶과 밀접히 관련된 지역명 또는 지역의 상징물이나 정체성을 상품화, 수익화 하려는 지역자원 개발의 일환으로 향토산업육성사업이 시작되었으나 아직까지 향토자원의 조사에서 산업화까지 일관되게 적용될 수 있는 방법의 개발은 부족한 실정이다. 본 연구에서는 추사김정희문화상품화 사례 연구를 대상으로 지역의 특징, 고용, 수요를 바탕으로 향토자원의 발굴, 사업화 방향의 결정, 사업내용을 도출하는 과정을 정리하였다. 연구 방법과 내용은 향토자원의 평가, 관련 주요산업의 결정, 사업내용의 도출 등 세 가지 부분으로 구성된다. 그 첫 번째 작업으로 향토자원의 목록을 작성하고 관련전문가를 대상으로 중요도와 산업화 가능성에 대한 평가를 진행하여 중심자원을 설정하였다. 두 번째로 입지계수를 응용하여 사업체수와 고용인원으로 대상지역의 보조사업계수를 설정하여 주요 관련 산업을 결정하였다. 세 번째로 방문객을 대상으로 한 설문조사를 진행하여 향토자원에 대한 인지도조사와 사업내용을 결정하였다. 마지막으로 사업추진결과를 정리하였으며, 향후 향토자원산업화사업에서 고려해야 할 시사점을 도출하였다. There are many local resources industrialization projects for regional development in South Korea but a lack of method for being adapted for project planning from survey of local resources to commercialization. In this research, we composed local resource commercialization process with a case study of Chusa Kimjeonghee cultural assets commercialization project considering regional characteristics of resources, employment, and needs. This research is composed with three parts such as resource assessment, main manufacturing area selection, and project contents development. In first step, local resource lists are gathered and graded by expert survey with the item of importance and industrialization possibility. In second step, we proposed project asssistant coefficient with numbers of enterprises and employment data by manufacturing are gathered in national and target area level. In third step, we propose questionnaire survey items for developing project contents based on customer needs. Finally we summarized project results and induced implications for future cultural assets commercialization projects.