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      • KCI등재
      • KCI등재

        한국형 우울장애 약물치료 알고리듬 (Ⅳ) : 우울장애의 아형 및 부작용에 따른 항우울제의 선택과 여성우울장애에서의 치료전략

        전현태,이상열,김원,민경준,박원명,서정석,석정호,송해철,전덕인,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

        Objectives : In 2002, the Korean Medication Algorithm Project for Major depressive Disorder (KMAP-MD) was published, but there has been a need for a guideline about detailed issues of depressive disorder. We revised KMAP-MDD andreestablished Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2006. Methods : A questionnaire had been developed by the executive committee for KMAP-DD. The review committee consisted of 101 experienced psychiatrists. From the total of 22 questions in the questionnaire, 7 questions were evaluated for these subjects . We classified the expert opinions to 3 categories according to its confidence interval; first, second and third line. Results : SSRI and venlafaxine were the first line antidepressants (AD) for atypical and melancholic depression. For dysthymic disorder and minor depressive disorder, SSRI was recommended as the first line medications. Only AD medications was a preferred initial strategy for treating premenstrual dysphoric disorder, mild to moderate and severe non-psychotic postpartum depression. In severe psychotic postpartum depression, combination therapy of AD and atypical antipsychotics was the treatment of choice. SSRI was preferred when considering sedation, anticholinergic and cardiovascular adverse effects. Also, experts recommended mirtazapine against gastrointestinal adverse effects and bupropion in avoiding sexual dysfunction. Conclusion : These results suggest that clinicians have to consider both clinical situations and drug adverse effects in the choice of antidepressant medications.

      • KCI등재

        감정표현불능증(Alexithymia), 신체적 호소, 정서 및 어휘의 관계

        전현태,이귀행,김재현,김한주,유용진,소광,Jeon, Hyun-Tae,Lee, Kuy-Haeng,Kim, Jae-Hyun,Kim, Han-Joo,Yoo, Yong-Jin,So, Kwang 한국정신신체의학회 2000 정신신체의학 Vol.8 No.1

        Objectives : This study aimed to examine a correlation between the somatic complaints, emotion, vocabulary and alexithymia as a component of personality in normal persons. Methods : 204 subjects were collected by age-based systematic sampling from the 662 persons without confirmed medical illness. We used the Korean version of 20-item Toronto Alexithymia Scale(TAS-20K) to measure alexithymia. The somatic complaints were checked by the list of somatic symptoms on the diagnostic criteria of somatization disorder and major depressive episode in DSM-IV. The vocabulary was evaluated by the total number of associating-words from the spontaneous association of word and the secondary association to given words. The anxiety and depression were evaluated using 5-point self-report scale. Results : 1) The degree of alexithymia was significantly correlated with the somatic complaints, anxiety, depression. 2) The somatic complaints were significantly correlated with the anxiety and depression. 3) The number of associating-words showed negative correlation with the age. 4) The degree of alexithymia was not correlated with the number of associating-words. Conclusion : The more degree of alexithymia increased, the more somatic complaints appeared. There was a significant correlation between the degree of alexithymia, anxiety and depression. But the degree of alexithymia was not correlated with the amount of vocabulary. 연구목적 : 본 연구는 정상 성인에서 성격의 일반적인 특정으로서의 감정표현불능증과 신체적 호소, 정서상태 및 어휘와의 상관관계를 알아봄으로써 감정표현불능증에 대한 이해를 넓히고자 하였다. 방법 : 신체적 질환을 가지고 있지 않은 정상 성인에서 한국판 20항목 Toronto 감정표현불능증 척도(TAS-20K), 신체적 호소, 연상한 단어의 수, 우울과 불안을 정도를 측정하여 그 결과들간의 상관관계를 알아 보았다. 총 662명을 평가한 후 체계적 표본추출 방법을 이용하여 다시 204명을 선택하였다. 결과 : 1) 감정표현불능증의 정도는 신체적 호소, 불안, 우울의 정도와 유의한 상관관계를 보였다. 2) 신체적 호소는 불안, 우울의 정도와 유의한 상관관계를 보였다. 3) 연상한 단어의 수는 나이와 부적 상관관계를 보였다. 4) 강정표현불능증의 정도는 연상한 단어의 수와 유의한 상관관계를 보이지 않았다. 결론 : 감정표현불능증의 정도가 심할수록 신체적 호소는 더 많으며 이는 불안, 우울의 정도와 연관되어 있었으나 어휘의 양과는 유의한 관계를 발견할 수 없었다.

      • KCI등재

        로하스 라이프스타일이 건강식 레스토랑 선택, 신뢰, 만족과 충성도에 미치는 영향

        전현태,이준혁,이경일 한국호텔관광학회 2022 호텔관광연구 Vol.24 No.1

        본 연구는 LOHAS에 대한 인식이 건강식 레스토랑 선택, 신뢰, 만족, 충성도 등의 관계를 파악하고자 시도하였다. 또한 각 경로별로 성별, 연령별 차이를 분석하고자 하였다. 이러한 시도는 최근 COVID-19로 인해 외식산업에서 안전에 대한 욕구가 자연스럽게 나타났으며 또한 건강식 레스토랑에 대한 관심도 증가하고 있는 추세이어서 매우 시의적절한 연구라고 생각된다. 본 연구는 엠브레인 조사업체의 도움으로 진행되었으며, 편의할당표본추출에 의해 20대, 30대, 40대가 각각 110명, 남성과 여성의 성비가 165명으로 같게 조사되었다. 또한 조사응답자들의 거주지도 전국적인 조사가 되어 LOHAS에 대한 인식 및 건강식 레스토랑 선택과 신뢰, 만족, 충성도 등의 관계를 파악하는 데에 매우 유용한 조사였다고 사료된다. 탐색적 요인분석을 통해 속성을 정제하여 LOHAS에 대한 인식에서는 지속가능성, 스트레스관리, 건강음식섭취, 영적생활 등의 요인이 도출되었으며, 건강식 레스토랑, 신뢰, 만족, 충성도 등의 요인이 도출되었다. 전체 구성요인에 대한 확인요인분석결과 평균분산 추출값이 .5 이상으로 추출되었으며, 개념 신뢰도는 .7 이상으로 추출되었다. 따라서 집중타당성이 있는 것으로 판단하였으며, 또한 상관관계분석을 통해 살펴본 결과 판별타당성이 있는 것으로 나타났다. 구조모형분석결과 LOHAS에 대한 인식에서 지속가능성과 스트레스관리는 건강식 레스토랑 선택에 영향을 미치는 것으로 나타났으며, 건강식 레스토랑은 신뢰 및 만족에 유의적인 정의 영향을 미치며, 신뢰는 만족에 만족은 충성도에 유의적인 정의 영향이 있는 것으로 나타났다. 그러나 신뢰는 충성도에 유의적인 영향력이 없는 것으로 나타났다. 이하에서 연구의 시사점 및 한계점을 논하였다.

      • KCI등재

        항우울제가 LETO쥐의 에너지 대사에 미치는 영향

        전현태,조근호,안영균,김홍태,기백석 대한정신약물학회 2009 대한정신약물학회지 Vol.20 No.4

        본 연구에서는 실험동물에서, 항우울제 투여 이후 발생하는 체중 및 식이 섭취량의 변화와 식이 효율을 비교하고, 혈액 및 세포 조직에서의 대사 관련 물질과의 연관성에 대해 확인하였다. 연구 결과 항우울제 투여 이후 식이 섭취량은 모든 약물 투여군에서 저하되었으며, 식이 효율은 fluoxetine 투여군에서 감소하였다. 실험동물에서 혈액 및 조직을 이용하여 진행한 연구에서 amitriptyline 투여군과 mirtazapine 투여군은 지방세포에서 PGC-1β, UCP-1, UCP-2, UCP3 mRNA의 발현이 유사한 결과를 보였으며, fluoxetine 투여군은 leptin과의 유의한 연관성이 나타났다. 이는 항우울제가 에너지 대사에 있어 항우울제의 기전에 따라 차이를 나타낼 가능성을 제시한다. Objectives:A diverse range of adverse effects has been linked to the application of antidepressants for the treatment of depressive disorder. Recently, evidence has been emerging of the adverse metabolic effects of antidepressants. This study investigated the effects of antidepressants on plasma glucose and other factors in the fat and muscle tissue relating to metabolism. Methods:Long-Evans-Tokushima-Ostuka (LETO) rats were used to evaluate the effects of different antidepressants. Amitriptyline, fluoxetine, and mirtazapine were administered to each of three subgroups for 4 weeks, between 11 and 15 weeks old, while a fourth subgroup was administered no antidepressant during the same period. Changes of weight and daily intake were monitored. Tissues and blood were collected at 15 weeks. Results:The fluoxetine subgroup showed lower weight gain and lower food efficacy ratio than did the other subgroups. Blood glucose and other circulating factors showed no significant differences among groups, except for the leptin levels of the fluoxetine subgroup. However, the amitriptyline and mirtazapine subgroups showed similar patterns in the response of mRNA expression of peroxisome proliferator-activated receptors gamma cofactor-1 and uncoupling protein-1, 2, 3. Conclusion:These results could indicate possible differences in metabolic response based on the kind of antidepressant used.

      • KCI등재

        Comparative Study of Laparoscopy-Assisted versus Open Subtotal Gastrectomy for pT2 Gastric Cancer

        전현태,김기한,김민찬,정갑중 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.5

        Purpose: Laparoscopy-assisted distal gastrectomy (LADG) is a widely accepted surgery for early gastric cancer. However, its use in advanced gastric cancer has rarely been studied. The aim of this study is to investigate the feasibility and survival outcomes of LADG for pT2 gastric cancer. Materials and Methods: Between January 2004 and December 2009, we evaluated 67 and 52 patients who underwent open distal gastrectomy (ODG) and LADG, respectively, with diagnosis of pT2 gastric cancer. The clinicopathological characteristics, postoperative outcomes, and survival were retrospectively compared between the two groups. Results: There were statistically significant differences in the proximal margin of the clinicopathological parameters. The operation time was significantly longer in LADG than in ODG (207.7 vs. 159.9 minutes). There were 6 (9.0%) and 5 (9.6%) complications in ODG and LADG, respectively. During follow-up periods, tumor recurrence occurred in 7 (10.4%) patients of the ODG and in 4 (7.7%) patients of the LADG group. The 5-year survival rate of ODG and LADG was 88.6% and 91.3% (p=0.613), respectively. In view of lymph node involvement, 5-year survival rates were 96.0% in ODG versus 97.0% in LADG for patients with negative nodal metastasis (p=0.968) and 80.9% in ODG versus 78.7% in LADG for those with positive nodal metastasis (p=0.868). Conclusion: Although prospective study is necessary to compare LADG with open gastrectomy for the treatment of advanced gastric cancer, laparoscopy-assisted distal gastrectomy might be considered as an alternative treatment for some pT2 gastric cancer.

      • 러너베인 깃수의 변화에 따른 소형 튜블러 수차의 성능해석

        전현태(Hyun-Tae Jeon),김유택(You-Taek Kim),남청도(Chung-Do Nam),최영도(Young-Do Choi),이영호(Young-Ho Lee) 한국마린엔지니어링학회 2008 한국마린엔지니어링학회 학술대회 논문집 Vol.2008 No.-

        Currnetly, various renewable energy develop have been investigated. Small hydropower among renewable energy is suitable for the real situation of domestic, because it is clean, renewable and abundant energy resources to develop. In this study, the hydraulic turbular turbine is proposed for small hydropower development. The hydraulic tubular turbine using a differential pressure of internal tube is suited to low-head, high-flow rate. This study analyzed the performance that compared the micro hydraulic tubular-type turbine by CFD with the model of 5㎾ micro tubular-turbine by experiment. In this study, The CFD code used ANSYS CFX that is commercial CFD code for CFD analysis and examines the performance with the number of runner vane.

      • 선회류에 의한 흡출관의 내부유동 해석

        전현태(H. T. Jeon),남상현(S. H. Nam),최영도(Y. D. Choi),김유택(Y. T. Kim),이영호(Y. H. Lee) 한국동력기계공학회 2007 한국동력기계공학회 학술대회 논문집 Vol.- No.-

        Small hydropower attracts attention because of its clean, renewable and abundant energy resources to develop. However, suitable draft-tube type is not determined yet because of its complicated internal flow and unstable turbine performance at the partial flow rate by the influence of the draft tube configuration. Therefore, it is necessary to study the influence of draft tube shape. The purpose of this study is to investigate the influence of the draft tube shape to its internal flow using CFD analysis. The results using two different computational models (draft tube without runner and draft tube with runner) are compared. The result which is computed without runner show that large secondary flow occurs at the curve area of the draft tube and the secondary flow goes out to the outlet of the draft tube. Another result which is computed with runner show that internal flow has complex flow in the whole flow field of the draft tube.

      • 소형 튜블러 수차의 가이드베인 깃수의 영향

        전현태(Hyun-Tae Jeon),남상현(Sang-Hyun Nam),김유택(You-Taek Kim),최영도(Young-Do Choi),남청도(Chung-Do Nam),이영호(Young-Ho LEE) 대한기계학회 2008 대한기계학회 춘추학술대회 Vol.2008 No.5

        Recently, Small hydropower attracts attention because of its clean, renewable and abundant energy resources to develop. This study is about tubular-type hydro turbine among renewable energy that is based on using the different water pressure levels in pipe lines. The purpose of this study is to investigate the influence of number of guide vane on the turbine performance, output power, and efficiency of tubular-type hydroturbine.

      • CFD에 의한 흡출관의 내부유동 해석

        전현태(Hyun-Tae Jeon),남상현(Sang-Hyun Nam),최영도(Young-Do Choi),김유택(You-Taek Kim),이영호(Young-Ho LEE) 대한기계학회 2007 대한기계학회 춘추학술대회 Vol.2007 No.10

        Small hydropower attracts attention because of its clean, renewable and abundant energy resources to develop. However, suitable draft-tube type is not determined yet because of its complicated internal flow and unstable turbine performance at the partial flow rate by the influence of the draft tube. Therefore, it is necessary to study the influence of draft tube shape. The purpose of this study is to investigate the influence of the draft tube shape to its internal flow using CFD analysis. The results show that large secondary flow occurs at the curve area of the draft tube and the secondary flow goes out to the outlet of the draft tube in the case of no-prerotation condition of the inlet flow.

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