경도인지장애 고령자의 우울과 인지기능 및 삶의 질에 대한 숲 체험 중재 프로그램의 효과

전아영,이강숙,이선미 한국보건교육건강증진학회 2019 보건교육건강증진학회지 Vol.36 No.3

Objectives: The purpose of this study was to investigate the effects of depression and cognitive function on the quality of life of elderly people diagnosed with mild cognitive impairment through various forest experience intervention program. Methods: The general characteristics of the tests subjects were verified by frequency and percentage, Fisher 's exact test, χ² test, and a t–test was conducted to verify the pre-and post- effects of the forest experience intervention program. Results: The results of this study showed that there was no significant difference in cognitive function between experiment group and control group experiencing forest experience intervention program, but it was statistically proved that depression of experimental group decreased and quality of life improved(p<.05). Conclusions: The study tried to present a new dementia prevention program that was different from the existing cognitive enhancement program method.

청소년의 거부민감성이 관계적 공격성에 미치는 영향: 분노반추의 매개효과

전아영,김은하 한국웰니스학회 2020 한국웰니스학회지 Vol.15 No.2

This study was to examine the effect of rejection sensitivity on adolescents and relational aggression and the mediation effect of anger rumination. 390 adolescents residing in Gyeonggi-do participated in this study. The collected data were analyzed by Pearson’s correlation, Mediated analysis, and Parallel multipath analysis using SPSS 23. The results were as follows. First, rejection sensitivity and anger rumination were positively correlated with relational aggression. anger rumination were positively correlated with relational aggression. Second, anger rumination had a partial mediation effect on the relationship between rejection sensitivity and relational aggression. Third, the mediating effects of ‛thoughts of revenge' were significant in the effect of rejection sensitivity on relational aggression; however, ‛angry afterthoughts' and ‛understanding of causes' was not a mediating variable. Based on the results, implications and limitations of this study and suggestions for subsequent research were discussed. 본 연구에서는 청소년의 거부민감성이 관계적 공격성에 미치는 영향에서 분노반추의 매개효과를 검증하고자 하였다. 이를 위해 경기 지역의 청소년 340명을 대상으로 자료를 수집하여, 상관분석, 매개분석, 병렬다중매개분석을 실시하였다. 본 연구에서 확인한 결과는 다음과 같다. 첫째, 주요 변인들의 상관분석 결과, 청소년의 거부민감성과 관계적 공격성은 정적상관을 보였고, 거부민감성과 분노반추, 분노반추와 관계적 공격성 또한 정적상관으로 나타났다. 둘째, 분노반추는 청소년의 거부민감성과 관계적 공격성의 관계를 부분 매개하였다. 셋째, 거부민감성이 관계적 공격성에 미치는 영향에서 분노반추 하위변인들의 매개효과를 검증한 결과, ‘보복사고’만이 부분매개효과를 가졌고, ‘분노후사고’, ‘원인이해’의 매개효과는 통계적으로 유의하지 않은 것으로 나타났다. 본 연구결과를 바탕으로 시사점과 향후 연구에 대한 제안점을 논의하였다.

구아바 가지 추출물의 생리활성 및 간세포 보호 효과

전아영,김나은,천원영,김영화 한국식생활문화학회 2021 韓國食生活文化學會誌 Vol.36 No.2

This study evaluated the biological activity and cytoprotective effect of guava (Psidium guajava L.) branch against oxidative stress. The contents of vitamin C, beta-carotene, total carotenoids, quercetin and catechin determined were 26.783, 43.676, 65.083, 58.245, and 8.309 mg/100 g, respectively. To measure antioxidant activity, the guava branch was extracted using various concentrations of ethanol (60, 80, or 100%) and water. The highest content of polyphenols (0.245 mg gallic acid equivalent/mg residue) and flavonoids (0.128 mg cathechin equivalent/mg residue) was found in the 100% ethanol extract of the branch (E100). Moreover, E100 also possessed the highest radical scavenging activities and showed the highest inhibition rate of α-glucosidase (77.692%). E100 was the most effective extract to impart cytoprotectant activity against oxidative stress in HepG2 cells. Taken together, our results determine the promising antioxidant activity of guava branch, and indicate the potential to be applied as a natural antioxidant.

박리화와 재적층법을 통한 K₂La₂Ti₃O₁₀부터 유전성 Bi_4-xLa_xTi₃O₁₂(x~2)의 합성

전아영,고지은,김종영,Jeon, A Young,Ko, Jieun,Kim, Jong-Young 한국결정성장학회 2013 韓國結晶成長學會誌 Vol.23 No.1

본 연구팀에서는 층상형 페로브스카이트 구조를 갖는 Ruddlesden-Popper 구조의 $K_2La_2Ti_3O_{10}$의 박리화를 통해 Aurivillius 구조의 $Bi_{4-x}La_xTi_3O_{12}$(x~2) 페로브스카이트 산화물을 성공적으로 합성하였다. 박리화된 란타늄 티타네이트 나노시트는 BiOCl 나노결정구조와 반응시켜 $Bi_{4-x}La_xTi_3O_{12}$(x~2) 결정을 얻어내었다. 박리화된 나노시트 현탁액은 $K_2La_2Ti_3O_{10}$으로부터 수소화된 $H_2La_2Ti_3O_{10}$의 층간에 에틸아민을 삽입시킴으로써 얻어내었다. 투과전자현미경(TEM) 분석을 통해, 란타늄 티타네이트가 에틸아민에 의해 박리화된 것을 확인할 수 있었다. X-선 회절분석(XRD)을 통해, 박리화된 란타늄 티타네이트와 BiOCl의 재적층과정을 거쳐 $700^{\circ}C$ 이상의 열처리 조건에서 $Bi_{4-x}La_xTi_3O_{12}$(x~2)로 형성된 것을 확인할 수 있었다. We have successfully synthesized $Bi_{4-x}La_xTi_3O_{12}$ (x~2) having Aurivillius-type layered perovskite structure from exfoliated layered perovskite oxide of $K_2La_2Ti_3O_{10}$ with Ruddlesden-Popper structure. The reaction between the exfoliated lanthanum titanate nanosheets and BiOCl nanocrystal resulted in the formation of polycrystalline $Bi_{4-x}La_xTi_3O_{12}$ (x~2) after heating above $700^{\circ}C$. Colloidal suspension of the nanosheets could be obtained by intercalating ethylamine (EA) into the protonated lanthanum titanate, $H_2La_2Ti_3O_{10}$, derived from $K_2La_2Ti_3O_{10}$. Transmission electron microscopic (TEM) analysis show that the exfoliated lanthanium titanate nanosheets have a thickness of a few nano meters. According to X-ray diffraction (XRD) analysis, the exfoliated lanthanium titanate was found to be transformed into $Bi_{4-x}La_xTi_3O_{12}$ (x~2) after restacking with BiOCl and subsequent thermal treatment at > $700^{\circ}C$.

우리나라에서 섭취하는 나물류의 수용성 비타민 함량

전아영,김영화 한국식품영양과학회 2019 한국식품영양과학회 학술대회발표집 Vol.2019 No.10

뇌졸중 환자에서 시각적 되먹임 훈련이 손목관절의 고유수용감각에 미치는 효과

전아영 대한뇌졸중학회 2003 Journal of stroke Vol.5 No.1

Background : It is well known that stroke patients with significantly impaired proprioception are associated with poor functional outcome. The purpose of this study is to evaluate usefulness of visual feedback training to improve proprioception of the affected wrist joint in stroke patients. M e t h o d s : We performed proprioceptive visual feedback training in 10 stroke patients with impaired proprioception. They felt the sense of direction on wrist joint, but the proportion of correct response on screening test was below 60%. We had set 5 angles in every 30 degree between flexion 60°and extension 60°of wrist joint, and we moved the patient’s wrist joint to each angle randomly and had them choose whichever angle that they felt to be compatible. We also let them see the result of the test. They were trained everyday for 2 weeks. We examined proprioceptive function in wrist joint before training, after training and 30 minutes later on training. Results : The proprioception of the wrist joint in stroke patients was improved by visual feedback training and improved proprioception continued 30 minutes later on training. Conclusion : Visual feedback training may improve proprioception in patients with stroke.

산화적 스트레스에 대한 여주(Momordica charantia Linn.)잎의 항산화 활성 및 간세포 보호능

전아영,천원영,윤지민,김대중,김영화,Jeon, Ahyeong,Cheon, Wonyoung,Yoon, Jimin,Kim, Dae-Jung,Kim, Younghwa 한국식생활문화학회 2020 韓國食生活文化學會誌 Vol.35 No.6

This study examined the bioactive compound content and the antioxidant activities of bitter melon (Momordica charantia Linn.) leaves. The content of vitamin C, beta-carotene, and total carotenoids was 69.77, 45.68, and 65.08 mg/100 g, respectively. To investigate the antioxidant capacity, bitter melon leaves were extracted using various concentrations of ethanol (60, 80, or 100%). Highest content of total polyphenols (18.07 mg gallic acid equivalent/g) and flavonoids (4.53 mg cathechin equivalent/g) was found in the 100% ethanolic extract of the leaves (E100). Also, the E100 extract showed the highest levels of 2,2'azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) and α-α-diphenyl-β-picrylhydrazyl (DPPH) free radical scavenging activities. Reducing power was also the highest (39.21 mg Trolox equivalent/g) in E100 extract. The E100 extract effectively inhibited lipid peroxidation by 91.45% compared to the control group. Also, the E100 extract showed a cytoprotective effect against oxidative stress in HepG2 cells and decreased the generation of intracellular reactive oxygen species. These results suggest that bitter melon leaves could be regarded as a potential source of natural antioxidants.

청소년 사이버폭력 피해 척도개발 및 타당화

전아영,정여주,김한별 한국상담학회 2016 한국상담학회 학술대회 논문집 Vol.2016 No.8

다발성 골수종 환자에서 Bortezomib에 의한 말초신경병증 발생과 위험인자 분석

전아영,김성환,김귀숙,이혜숙,김향숙 한국병원약사회 2014 병원약사회지 Vol.31 No.3

Bortezomib acts by disrupting ubiquitin-proteasome pathway which regulates proteinhomeostasis within the cell and has demonstrated significant activity mainly against recurrent ornewly diagnosed multiple myeloma(MM). Among bortezomib-related side effects, peripheral neuropathy(PN) as main dose-limiting non-haematological toxicity can substantially affect thequality of life of patients. It typically requires dose-reduction, delay, or even premature terminationof successful treatment. Therefore, predicting the risk for neuropathy before the therapyand a proper management of neurotoxicity are very important considerations. The aim of this study was to evaluate the incidence of PN, risk factors, and prior exposure topotentially neurotoxic chemotherapy. A total of 108 patients with multiple myeloma(MM) wereincluded, who received bortezomib in Seoul National University of Hospital(SNUH) from May 2005 to April 2008. A retrospective chart review was performed on SNUH patients’ElectronicMedical Records(EMR), and the SPSS Statistics 19.0 was used for analysis. In univariate analysis, no correlation was found between the development of PN, sex, or age,but creatinine level (Scr≥2)(48% vs 78%, p=0.007, OR=0.264), presence of DM(50% vs 76%,p=0.034, OR=0.324) and number of therapy cycles(N>3)(84% vs 57%, p=0.002, OR=4.046) weresignificantly correlated with PN incidence. In a multivariate logistic regression, the risk of bortezomib-related PN was lower in patients whose creatinine level was high(Scr≥2)(OR=0.248) andgreater in patients treated with high number of bortezomib cylces(N>3)(OR=4.235). Concerning that the prior exposure to chemotherapy could exacerbate neurotoxicity, there waslower incidence of PN in the prior bortezomib treated group(38% vs 62%, p=0.007), prior bortezomibwith thalidomide treated group(36% vs 63%, p=0.003), and prior bortezomib with vincristinetreated group(37% vs 60%, p=0.026).

회전근개 파열 환자의 파열 크기에 따른 견관절 최대 우력의 비교

전아영,유연식,강석원,장기언,서정훈,최은희 대한재활의학회 2009 Annals of Rehabilitation Medicine Vol.33 No.5

Objective: To investigate the peak torque of shoulder according to the size of the rotator cuff tear. Method: With 26 patients of unilateral rotator cuff tear, we measured the concentric isokinetic peak torque of shoulder, using Con-Trex isokinetic dynamometer (CMV AG, Deubendorf, Switzerland). We measured flexion, extension, abduction, adduction, external rotation, and internal rotation torques and calculated the peak toque ratio of flexion/ extension, abduction/adduction and external rotation/internal rotation. Before the test, we injected 1% lidocaine to the subacromial bursa to minimize the error that can be caused by pain. The difference of peak torque according to the size of tear was compared. Results: Comparing the peak torque between affected and sound side, significant difference in flexion, extension, abduction, adduction, internal rotation, and external rotation were shown, but there were no difference in peak torque's ratio in flexion/extension, abduction/adduction, and internal rotation/external rotation. When we compared the peak torque according to the tear size, it didn't show significant difference and also there were no difference of peak torque's ratio in flexion/extension, abduction/adduction, internal rotation/external rotation. Conclusion: When we measured the shoulder's strength of rotator cuff tear, peak torque decreased in all motion. But the peak torque's loss and peak torque’s ratio is not related with size of tear. Objective: To investigate the peak torque of shoulder according to the size of the rotator cuff tear. Method: With 26 patients of unilateral rotator cuff tear, we measured the concentric isokinetic peak torque of shoulder, using Con-Trex isokinetic dynamometer (CMV AG, Deubendorf, Switzerland). We measured flexion, extension, abduction, adduction, external rotation, and internal rotation torques and calculated the peak toque ratio of flexion/ extension, abduction/adduction and external rotation/internal rotation. Before the test, we injected 1% lidocaine to the subacromial bursa to minimize the error that can be caused by pain. The difference of peak torque according to the size of tear was compared. Results: Comparing the peak torque between affected and sound side, significant difference in flexion, extension, abduction, adduction, internal rotation, and external rotation were shown, but there were no difference in peak torque's ratio in flexion/extension, abduction/adduction, and internal rotation/external rotation. When we compared the peak torque according to the tear size, it didn't show significant difference and also there were no difference of peak torque's ratio in flexion/extension, abduction/adduction, internal rotation/external rotation. Conclusion: When we measured the shoulder's strength of rotator cuff tear, peak torque decreased in all motion. But the peak torque's loss and peak torque’s ratio is not related with size of tear.