Role of Surgical Margin on Local Recurrence in High Risk Extremity Osteosarcoma: A Case-Controlled Study

전대근,송원석,공창배,조완형,조상현,이정동,이수용 대한정형외과학회 2013 Clinics in Orthopedic Surgery Vol.5 No.3

Background:The relationship between surgical margin and local recurrence (LR) in osteosarcoma patients with poor responses to chemotherapy is unclear. Moreover, the incidences of LR according to three different resection planes (bone, soft tissue, and perineurovascular) are not commonly known. Methods: We evaluated the incidence of LR in three areas. To assess whether there is a role of surgical margin on LR in patients resistant to preoperative chemotherapy, we designed a case (35 patients with LR) and control (70 patients without LR) study. Controls were matched for age, location, initial tumor volume, and tumor volume change during preoperative chemotherapy. Results: LR occurred at the soft tissues in 18 cases (51.4%), at the perineurovascular tissues in 11 cases (31.4%), and at the bones in six cases (17.2%). The proportion of inadequate perineurovascular margin was higher in the case group than in the control group (p = 0.01). Within case-control group (105 patients), a correlation between each margin status and LR at corresponding area was found in the bone (p < 0.001) and perineurovascular area (p = 0.001). Conclusions: LR is most common in soft tissues. In patients showing similar unfavorable responses to chemotherapy, the losses of perineurovascular fat plane on preoperative magnetic resonance imaging may be a valuable finding in predicting LR.

증착 온도에 따른 IZO 박막의 구조적 및 전기적 특성

전대근,이유림,이규만 한국반도체디스플레이기술학회 2011 반도체디스플레이기술학회지 Vol.10 No.3

In this study, we have investigated the effect of the substrate temperature on the structural and the electrical characteristics of IZO thin films for the OLED (organic light emitting diodes) devices. For this purpose, IZO thin films were deposited by RF magnetron sputtering under various substrate temperature. The substrate temperature has been changed from room temperature to 400℃. Samples which were deposited under 250 ℃ show amorphous structure. The electrical resistivity of crystalline-IZO (c-IZO) film was higher than that of amorphous-IZO (a-IZO) film. And the electrical resistivity showed minimum value near 150℃ of deposition temperature. The OLED device was fabricated with different IZO substrates made by configuration of IZO/α-NPD/DPVB/Alq3/LiF/Al to elucidate the performance of IZO substrate. OLED devices with the amorphous-IZO (a-IZO) anode film show better current density-voltage-luminance characteristics than that of OLED devices with the commercial crystalline-ITO (c-ITO) anode film. It can be explained that very flat surface roughness and high work function of a-IZO anode film lead to more efficient hole injection by reduction of interface barrier height between anode and organic layers. This suggests that a-IZO film is a promising anode materials substituting conventional c-ITO anode in OLED devices.

골육종의 예후인자

전대근,이종석,김석준,양현석,이수용,Jeon, Dae-Geun,Lee, Jong-Seok,Kim, Sug-Jun,Yang, Hyun-Seok,Lee, Soo-Yong 대한근골격종양학회 1997 대한골관절종양학회지 Vol.3 No.1

Osteosarcoma is the most common primary bony malignancy and its survivorship has been progressed markedly through refined chemotherapy and surgery. But still there are many non-responders and analysis of prognostic factors may be helpful for them. Two hundred and sixty-six patients were enlisted between Mar, 1985 and Sep. 1994. Among them our inclusion criteria were: 1)primary, nonmetastatic classical osteosarcoma 2)extremity in location 3)no prior treatment at other institute and completed neoadjuvant chemotherapy and surgery according to our protocol. One hundred and eleven cases were eligible. Analyzed factors were:age, sex, location, tumor size, and pathologic response. Statistical methods were log-rank test for univariate and Cox's test for multivariate analysis. Male to female ratio was 69:42 with an average age of 17.2 years. Locations of tumor were distal femur 59, proximal tibia 29, and proximal humerus 8. Tumor size were measured by its maximal diameter and 48 cases were above 10cm and 47 cases were below 10cm. For pathologic response, 57 cases showed more than 90% and 54 cases were less than that. Limb salvage procedure was 101 cases and amputation was 10 cases and their local recurrence rate were 3.6%. Average follow-up period was 24(9-78.2) months and their final status was CDF 86, AWD 8, NED 5, and DOD 12 cases. In univariate study: type of operation(p=0.005), tumor size(p=0.005), and pathologic response(p=0.02) were significant variables. Pathologic response(p=0.03) and type of operation(p=0.01) were meaningful prognostic factors on multivariate analysis. But the latter result was interpreted as a bias, so pathologic response remained as a sole meaningful prognostic factor. More aggressive chemotherapy will be needed to improve the survival.

항공관제용 다중 센서 자료 처리 소프트웨어 개발

전대근,은연주,김현경,염찬홍 한국항공우주학회 2012 한국항공우주학회 학술발표회 논문집 Vol.2012 No.11

항공관제용 감시자료처리시스템 (Surveillance Data Processing System: SDPS)을 구성하는 핵심 소프트웨어 중 하나인, 다중센서 다중 타겟 추적 소프트웨어 (Multi-Sensor Data Processing: MSDP)를 개발하였다. MSDP 는 기존 감시 센서인 레이더뿐만 아니라, ADS-B, Multilateration (MLAT) 등 차세대 감시센서 자료를 입력으로 하여 항공관제를 위한 시스템 항적을 생성하는 소프트웨어로서, 최신의 항적 추적기술인 Multiple Plot Variable Update, Interacting Multiple Model 등이 적용되었다. MSDP 에 의한 항적 추적의 정확도 분석을 위해, Eurocontrol 의 감시 표준의 요구사항을 기준으로 시험평가를 수행하였으며, 그 결과 요구사항을 만족함을 확인하였다. Multi-Sensor Data Processing (MSDP) Software as a core module of Surveillance Data Processing System (SDPS) is developed. MSDP processes not only radars but also ADS-B and Multilateration (MLAT) in order to produce system tracks for air traffic control. State-of-the-art tracking technologies such as Multiple Plot Variable Update (MPVU) and Interacting Multiple Model (IMM) are adopted for MSDP. Tracking performance test results based on the requirements in surveillance standards of Eurocontrol indicate that MSDP meets the requirements.

골연부 종양에서 저온 열처리한 자가골을 이용한 재건술

전대근,이종석,김석준,조완형,곽봉준,이수용,Jeon, Dae-Geun,Lee, Jong-Seok,Kim, Sug-Jun,Cho, Wan-Hyeong,Kwag, Bong-Jun,Lee, Soo-Yong 대한근골격종양학회 1998 대한골관절종양학회지 Vol.4 No.2

Although autoclaved autogenous bone reconstruction is one of the established procedures, it may have some problems in bone regeneration and mechanical property. The purpose of this study is to evaluate the efficacy of more biologic and anatomical reconstruction where allograft is not readily available. From Aug.1991 to Feb. 1996 the authors analyzed 32 cases of reconstruction with autogenous low heat treated bone. Autogenous graft sites were humerus 4, tibia 4, pelvis 9, and 15 femur. Average follow-up period was 23(range;12-51) months. There were 49 graft-host junctional sites. Diaphysis was 22, metaphysis 10, and flat bone 17. Average duration of healing for the 38 united sites was 7 months. Average union time for each anatomical area 8 months in 19 diaphysis, 12 months in 7 metaphysis, and 12.7 months in 12 flat bone(pelvis). Eleven nonunion sites consisted of 3 diaphysis(3/22), 3 metaphysis(3/10), and 5 flat bone(5/17). Complications other than nonunion were local recurrence(4), bone resorption(3), graft fracture(2), osteomyelitis(1), metal failure(2), and wound infection(1). Initial bone quality and stable fixation technique was important for union rate. Plate and screw is a good method for diaphyseal lesion. Metaphyseal and flat bone are weak area for rigid fixation and one stage augmentation with iliac bone graft can be a salvage procedure.

소비윤리가 과시소비성향과 복제품 구매행동에 미치는 영향

전대근,박선미 한국의류학회 2011 한국의류학회 학술대회논문집 Vol.2011 No.1

4D 궤적 기반 항공교통흐름관리 기술 연구

전대근 대한교통학회 2021 대한교통학회 학술대회지 Vol.85 No.-

항공교통 흐름관리(ATFM, Air Traffic Flow Management)는 안전하고 질서정연하고 신속한 항공교통의 흐름을 위한 서비스로서, 항공교통량이 항공교통관제 당국이 수용 가능한 범위 내에서 유지될 수 있도록, 교통흐름을 예측하여 사전에 조절하는 것을 목적으로 한다. 본 연구에서는 ATFM에 요구되는 핵심 기술을 4차원 정밀 궤적 예측 기술, 교통수요량/수용량 예측 및 감시 기술, 수용량 대비 수요량 불균형 발생 시 요구되는 항공교통 흐름관리 조치(TMI, Traffic Management Initiative) 생성 기술, 시뮬레이션 및 분석 기술로 구분하고, 이와 관련한 최신 기술/연구동향을 분석하였다. 또한, 분석 결과를 바탕으로, 우리나라 항공교통환경의 특수성, 주변국으로부터의 흐름관리 요구사항, 향후 확장성 등을 종합적으로 고려하여, 우리나라의 효율적 ATFM을 위해 필요한 연구주제를 식별하였다.

Stage IIB 골육종환자에서 항암 화학요법의 종류에 따른 생존율 비교

전대근,이수용,이종석,김태완,정동환,Jeon, Dae-Geun,Lee, Soo-Yong,Lee, Jong-Seok,Kim, Tae-Wan,Chung, Dong-Hwan 대한근골격종양학회 1995 대한골관절종양학회지 Vol.1 No.1

From Sept. 1986 to Dec. 1992, seventy three cases of Enneking's stage IIB osteosarcoma of extremities, which were proved histologically, took neoadjuvant chemotherapy and completed our protocol. Their average age was 16.7 years(7 to 57). For neoadjuvant chemotherapy, 37 cases took high dose methotrexate(HDMTX)-adriamycin(ADR)-cisplatin(CDDP) regimen(HDMTX group) and 36 cases took ADR-CDDP(ADR-CDDP group). The average follow up was 17 months(2-63). According to Kaplan-Meier's plot, 5-year continuously disease free survival for whole 73 cases of neoadjuvant group was 45.2%, for HDMTX group 68.4%, for ADR-CDDP group 26.6%. There was significant stastical difference between these two groups(p<0.001), with log-rank test. There can be a different survival according to the chemotherapeutic protocols. Better results can be achieved through refined protocol and effective chemotherapeutic agents.

돈에 대한 태도가 명품과 SPA 상품 구매에 미치는 영향

전대근,박선미 한국의류학회 2011 한국의류학회 학술대회논문집 Vol.2011 No.1

일측성 척추마취와 양측성 척추마취가 Midazolam의 진정효과에 미치는 영향

전대근 대한마취과학회 2005 Korean Journal of Anesthesiology Vol.48 No.1