낙엽송층버섯의 Nitric Oxide 생성저해 물질

장현진,김안근,표명윤,양기숙,Jang, Hyun-Jin,Kim, Ahn-Keun,Pyo, Myoung-Yun,Yang, Ki-Sook 대한약학회 2007 약학회지 Vol.51 No.6

The anti-inflammatory activity of fruit body of Phellinus pini was investigated by activity-guided fractionation. From the screening of each fraction for the inhibitory activity of NO production in lipopolysaccaride (LPS) activated RAW 264.7 cells, methanol extract and its hexane soluble fraction of Phellinus pini exhibited inhibition of NO production compared with LPS control without toxicity. The hexane soluble fraction showed dose-dependent inhibition of NO production. The active hexane fraction was repeatedly chromatographed over silica gel, ergosta-7,24(28)-dien-3-ol(1) and ergosterol peroxide (2) were isolated and identified. Ergosterol derivatives were inhibited NOS activation, $IC_{50}$ of them were $18.9{\pm}3.9{\mu}M$ (1) and $20.4{\pm}4.5{\mu}M$ (2).

일개 한방병원에서의 흉요추 압박골절 입원 환자에 대한 통계적 분석: 후향적 차트리뷰

장현진,김소정,김민주,최현규,박필제,강연수,정정교,전주현,김영일,Hyun jin Jang,So jeong Kim,Min Ju Kim,Hyeon Kyu Choi,Pil Je Park,Yeon Soo Kang,Jeong Kyo Jeong,Ju Hyun Jeon,Young Il Kim 대한한의학회 2023 대한한의학회지 Vol.44 No.2

Objectives: This study was designed to statistically analyze patients hospitalized for thoracolumbar compression fractures at Daejeon University Daejeon Korean Medicine Hospital from January 1, 2017 to December 31, 2021. Methods: A total of 62 patients were analyzed through electronic medical records in this study. The extracted data was analyzed using IBM SPSS ver.27.0. Results: 1. Traffic accident patients were more likely to reduce pain by more than half compared to falls and other patients. Patients without spinal disease were more likely to reduce pain by more than half compared to those without. The shorter the absolute bed rest and the longer the hospital stay, the higher the probability of pain reduction by more than half. 2. The duration of pain half-reduction was longer in patients with diabetes than in patients without diabetes. 3. The longer the hospitalization period and the shorter the absolute bed rest period, the less pain was reported upon discharge. Males complained of less pain at discharge than females, and patients without spinal disease complained less than those without. Patients who did not receive absolute bed rest complained of less pain upon discharge than those who did not. Conclusions: This study included patients hospitalized for thoracolumbar compression fractures and showed that etiology, absolute bed rest period, hospitalization period, gender, spinal disease, diabetes statistically affected the degree of pain reduction.

이제마(李濟馬)의 난치병(難治病)에 대(對)한 시각(視角)에 관(關)한 연구(硏究)

장현진,Jang, Hyun Jin 사상체질의학회 1995 사상체질의학회지 Vol.7 No.2

Lee Je Ma (1837~1900) wrote the DongEuSuSeBoWon in 1894. Constitutional Medicine what is called Sasang Medicine has originated from him. In this book he refers to mild, serious, intractable, incurable and fatal disease. In the sight of his Medical theory each state of disease deserves to be researched. 1. In the case of Soumin exhaustion of Yang, Taeyang-Kwolum, noxious Yin, Yang is kept in the exterior by excessive Yin in the interior, middle diabetes and swelling belong to intractable disease and solid mass in the right epigastric zone belongs to fatal disease. 2. In the case of Soyangin exhaustion of Yin, lower diabetes, afternoon fever due to deficiency of Yin, spitting blood and swelling belong to intractable disease and distention of abdomen with gas or fluid belongs to fatal disease. 3. In the case of Taeumin syncope due to chills, dryness-heat, diabetes, pain of chest and abdomen and swelling belong to intractable disease and apoplexy with dosed eyes belongs to fatal disease. 4. In the case of Taeyangin vertebral disease makes flaccidity of lower limbs and dysphagia with vomiting of frothy fluid belongs to fatal disease.

철액수(鐵液水)의 효능(效能)에 관(關)한 실험적(實驗的) 연구(然究)

장현진,Jang, Hyun Jin 사상체질의학회 1991 사상체질의학회지 Vol.3 No.1

These studies were conducted about the effects of Ferric oxide in the aspect of the basic pharmacology through experimental animals with the investigation of its clinical effects on oriental medical literatures of Ferric oxide. The results were as follows: 1. The analgenic effects induced by acetic acid were significant. 2. The anticonvulsive effects induced by ECT unit were significant. 3. The sedative effects in Rotor rod method were significant. 4. The number of platelets was increased but not significantly. 5. Prothrombin time was decreased significantly. 6. Fibrinogen was increased but not significantly. 7. The degree of concentration of FDP was decreased significantly. According to the above results, it is considered that Ferric oxide retains effectiveness on the treatment of cerebral stroke.

도심형 복합쇼핑몰 공간구성 변화에 관한 연구

장현진 ( Hyun Jin Jang ),허범팔 ( Bum Pall Hur ) 한국기초조형학회 2013 기초조형학연구 Vol.14 No.5

1920년대에 이미 쇼핑몰의 효시가 태동된 미국이나 1950년대 지하철 역사를 중심으로 개발이 시작된 일본과 같은 선진국과 비교해 볼 때 우리나라 복합쇼핑몰의 역사는 매우 짧고 비교 대상 또한 적어 복합쇼핑몰의 공간구성에 관련된 연구가 제대로 진행되지 못하였었다. 하지만, 최근 국내 백화점 업계에서 복합쇼핑몰 사업에 참여하면서 복합쇼핑몰의 수가 급속도로 증가하고 있어 국내 복합쇼핑몰 관련 연구에 박차를 꾀하고 있다. 따라서 본 연구 과정에서는 시대에 따라 일어나는 사회 문화적 변화가 복합쇼핑몰 발전 형태에 미치는 영향을 이해하고, 도심형 복합쇼핑몰의 공간구성이 어떤 특성과 유형을 가지고 변화되고 있는지 연구 하고자한다. 먼저, 쇼핑몰의 개념, 특성, 유형을 이해하고 사회 문화적 변화가 복합쇼핑몰 발전 형태에 미치는 영향과 국내외 쇼핑몰의 연혁과 성장배경에 관하여 이론적 고찰을 하였다. 국내 도심과 부도심 중심상권에 위치한 쇼핑몰 중 개점연도와 발전 형태에 따라 대형 몰, 현대적 쇼핑몰, 역사형몰, 도심형몰의 4가지 유형으로 세대를 분류하였고 각 세대의 사례 중 규모가 크고 최근에 오픈한 점포를 기준으로 4곳을 선정하여 개요 및 유형, 물리적 공간배치, 용도 및 시설구성, 실내디자인 구성요소를 통해 도심형 복합쇼핑몰 사례를 연구하고 시대별 사회 문화적 변화를 통해 다양한 발전 형태로 개발된 복합쇼핑몰의 공간구성 변화를 분석하였다 There were shopping malls already in the US in the 1920s, Japan established their subway system in the 1950s; compared to these advanced countries, Korea has a relatively short history of complex shopping malls and there is not enough foundation therefore not many studies regarding spatial configuration of complex shopping malls have been done so far. However department stores are recently getting involved in complex shopping mall business, which increased the number of complex shopping malls and accelerated research and studies regarding complex shopping malls in the country. This study identifies the effect of social, cultural change on complex shopping mall development and the nature and type of changes of urban complex shopping malls` spatial configuration. First, the concept, characteristics and types of shopping malls were discussed based on theories. The effect of social, cultural changes on complex shopping mall development and the history of shopping malls in Korea and other countries and the development were also discussed. Shopping malls located in civic centers and secondary central business districts are classified by development and year; 4 large malls that were recently opened were selected to examine the types, physical spatial layouts, uses, configurations and interior designs; and changes of spatial configuration of complex shopping malls developed in various forms through social, cultural changes were analyzed.

디자인 전문잡지에 나타난 제품디자인 조형언어 서술 구조에 관한 연구

장현진 ( Hyun Jin Jang ),채승진 ( Sung Zin Chae ) 한국기초조형학회 2008 기초조형학연구 Vol.9 No.6

유아교육과 교수자의 온라인 수업에서의 어려움과 요구

장현진(Jang, Hyun Jin),김형미(Kim, Hyung Mee) 한국육아지원학회 2022 육아지원연구 Vol.17 No.2

Chlorella vulgaris의 흡광도, 클로로필 및 개체수 통합 영향에 근거한 중금속 및 나노입자 독성 조사

장현진(Hyun Jin Jang),이문희(Mun Hee Lee),이은진(Eun Jin Lee),양신(Xin Yang),공인철(In Chul Kong) 한국청정기술학회 2017 청정기술 Vol.23 No.1

본 연구에서는 중금속 7종(Cu, Cd, Cr, As(III), As(V), Zn, Ni) 및 나노입자 5종(CuO, ZnO, NiO, TiO₂, Fe₂O₃)에 대한 독성을 수계 대표 생물종인 녹조류 Chlorella vulgaris를 이용한 생물검정법으로 평가하였다. 조류에 미치는 영향은 흡광도, 클로로필 및 개체수 측정에 대한 결과를 통합하여 평가하였다. 중금속의 통합결과독성(TEC50) 순서는 Cr (0.7 ㎎ L<SUP>-1</SUP>) > Cu (1.7 ㎎ L<SUP>-1</SUP>) > Cd (3.2 ㎎ L<SUP>-1</SUP>) > Zn (3.9 ㎎ L<SUP>-1</SUP>) > Ni (13.2 ㎎ L<SUP>-1</SUP>) > As(III) (17.8 ㎎ L<SUP>-1</SUP>) ≫ As(V) (> 1000 ㎎ L<SUP>-1</SUP>)로 나타났다. 중금속은 측정종말점에 따라 일부 상이한 민감도와 독성이 조사되었다. 나노입자의 독성(TEC50) 순서는 ZnO (2.4 ㎎ L<SUP>-1</SUP>) > NiO (21.1 ㎎ L<SUP>-1</SUP>) > CuO (36.6 ㎎ L<SUP>-1</SUP>) > TiO2 (62.5 ㎎ L<SUP>-1</SUP>) > Fe2O3 (82.7 ㎎ L<SUP>-1</SUP>)로 나타났다. 나노입자는 측정종말점간에 비슷한 민감도와 독성을 보였다. 따라서 오염물의 독성을 평가하기 위해서 단일 방법에 의한 결과보다는 다양한 측정종말점의 통합결과에 근거한 접근이 적절할 것이다. In this study, toxicities of seven metals (Cu, Cd, Cr, As(III), As(V), Zn, Ni) and five metal oxide nanoparticles (NPs: CuO, ZnO, NiO, TiO₂, Fe₂O₃) were evaluated based on the growth of Chlorella vulgaris. Effect on algae growth was evaluated by integrating the results of absorption, chlorophyll content, and cell count. The toxicity rankings of metals was observed as Cr (0.7 ㎎ L<SUP>-1</SUP>) > Cu (1.7 ㎎ L<SUP>-1</SUP>) > Cd (3.2 ㎎ L<SUP>-1</SUP>) > Zn (3.9 ㎎ L<SUP>-1</SUP>) > Ni (13.2 ㎎ L<SUP>-1</SUP>) > As(III) (17.8 ㎎ L<SUP>-1</SUP>) ≫ As(V) (> 1000 ㎎ L<SUP>-1</SUP>). Slightly different orders and sensitivities of metal toxicity were examined depending on endpoints of algal growth. In case of NPs, regardless of endpoints, similar toxicity rankings of NPs (TEC50) were observed, showing ZnO (2.4 ㎎ L<SUP>-1</SUP>) > NiO (21.1 ㎎ L<SUP>-1</SUP>) > CuO (36.6 ㎎ L<SUP>-1</SUP>) > TiO2 (62.5 ㎎ L<SUP>-1</SUP>) > Fe2O3 (82.7 ㎎ L<SUP>-1</SUP>). These results indicate that an integrating results of endpoints might be an effective strategy for the assessment of contaminants.

초보 어머니들의 산후조리원 경험

장현진(Jang, Hyun Jin) 한국육아지원학회 2021 육아지원연구 Vol.16 No.1

본 연구는 첫 자녀를 둔 초보 어머니들의 산후조리원 경험 탐색을 목적으로 했다. 연구방법은 심층면담이며, 서울시에 위치한 A 산후조리원에 재원 한 초보 어머니 5명을 대상으로, 2018년 4월부터 8월까지 수집된 면담 자료를 전사한 후 질적 방법으로 분석했다. 본 연구의 연구결과는 다음과 같다. 첫째, 산후조리원에서 초보 어머니들은 ○○○의 엄마로서 시작하는 경험을 가졌다. 초보 어머니들은 산후조리원에서 엄마라는 이름으로 불리기, 모유수유와 승부 겨루기, 기대와 달리 채워지지 않은 엄마 역할에 대한 배움, 엄마라는 이름의 친구들이라는 경험을 가졌다. 둘째, 산후조리원에서 초보 어머니들은 엄마가 된 기쁨과 혼란을 느꼈다. 엄마로서 느끼는 축하선물, 출산 여성과 엄마 사이의 갈등, 초보 엄마로서의 불안함이 산후조리원 생활 동안 초보 어머니들에게서 나타났다. 본 연구는 산후조리원이 출산 직후 여성들이 어머니로서의 정체성을 형성하는 관문으로, 초보 어머니들의 역할 적응을 지원하는 장이 되어야 함을 시사한다. The purpose of this study was to explore first-time mothers’ experience in postpartum care center. In-depth interviews with five first-time mothers who were hospitalized at A postpartum care center in Seoul were conducted from April to August 2018. Interviews were transcribed and analyzed using qualitative methods. The results of this study are as follows. First, in postpartum care center, first-time mothers started their experience as mothers by being called mothers, competing breast feeding, learning the role of mothers with insufficient feeling, and making friends with mothers. Second, in postpartum care center, first-time mothers felt joy and confusion being a mother. They were congratulated as a mother, conflicting feelings as a woman and a mother, and anxiety as novice mothers. This study suggests that postpartum care centers are the gateway for women to form an identity as mothers after childbirth, and should be a place to support the role adaptation of first-time mothers.

영아에 대한 예비 유아교사의 은유 분석

장현진 ( Jang Hyun-jin ) 미래유아교육학회 2017 미래유아교육학회지 Vol.24 No.1

본 연구는 은유 분석을 통해 영아에 대한 예비 유아교사의 인식을 살펴보는 것이다. 연구대상은 수도권에 소재한 3년제 대학 유아교육과에 재학 중인 예비 유아교사 142명이다. 은유 분석은 질문지“영아는 ~이다. 왜냐하면 ~하기 때문이다.”에 기술된 내용을 토대로 내용분석 방법으로 실시했다. 은유 분석 결과 영아에 대한 예비 유아교사의 인식은 돌봄이 필요한 존재, 연약한 존재, 예측할 수 없는 존재, 환경의 영향을 받는 존재, 순수하고 사랑스러운 존재, 잠재력을 지닌 존재, 탐구 능력을 가진 존재, 성장하는 존재의 총 8가지로 범주화되었다. 각 범주를 빈도 분석한 결과, 예비 유아교사는 영아를 스스로 지식을 구성하고 세상을 탐구하는 능동적 존재보다는 돌봄과 보호가 필요한 대상으로, 그리고 교사나 부모에 의해 주어진 환경에 반응하는 수동적인 존재로 인식하는 경향이 높았다. 본 연구결과는 영아, 영아 보육에 관한 예비 유아교사의 다양한 관점을 알 수 있는 계기를 제공했으며, 나아가 영아 교사 양성 교육에 관한 시사점을 제시했다는 점에서 의의를 가진다. This study was to examine pre-service early childhood teachers` awareness of infant through metaphorical analysis. Study targets were 142 pre-service early childhood teachers who attend to 3-year colleges in the capital area, majoring in the department of early childhood education. For the metaphorical analysis, a content which is described in “Infants are ~ because they do ~.” was analyzed with the content analysis method. At the metaphorical analysis result, recognition of the pre-service early childhood teachers was categorized into a total of eight such as existence necessary for caring, feeble existence, unpredictable existence, existence receiving the influence of environment, pure and lovely existence, potential existence, existence having exploration ability, and growing existence. At the result of frequency analysis of each category, the pre-service early childhood teachers had a high tendency of recognizing infants as objects necessary for caring and detection rather than active existence that composes knowledge for himself/herself and explores the world and perceiving them as passive existence responding to environment given by teachers or parents. The study result provided an opportunity to know diverse viewpoints of pre-service early childhood teachers about infants and child care. Further, there is a meaning in that the study presented implication on education of training infant care teachers.