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Endoscopic Repair of Meningoencephalocele:A Case Report
장태영,김대형,이승준,김경태 대한비과학회 2004 Journal of rhinology Vol.11 No.1
Meningoencephalocele is a rare mass, usually occurring in childhood. This is the herniation of a part of an intracranialcomponent through the skull base defect. Embryologically, the defect result from closure failure of the anterior neuropore. This mass may include meninges (meningocele), meninges and brain (meningoencephalocele), or meninges, brain, and ventricles(meningoencephalocystocele). It is classified as occipital, parietal, basal, and sincipital on the basis of its anatomicallocation. In past, the treatment of this mass has been by neurosurgeons. The authors experienced a case of basal type intranasalmeningoencephalocele in 15 year-old male patient in which the mass protruded into the nasal cavity through thecribriform plate. It was excised successfully by the intranasal approach with nasal endoscopy, and the dural defect was closedby septal cartilage, fascia lata, septal mucosa, and fibrin glue.
장태영,김영효 대한배뇨장애요실금학회 2015 International Neurourology Journal Vol.19 No.3
Interleukin (IL) 33, a member of the IL-1 superfamily, is an “alarmin” protein and is secreted in its active form from damaged cells undergoing necrotic cell death. Mast cells are one of the main effector cell types in allergic disorders. They secrete a variety of mediators, including T helper 2 cytokines. As mast cells have high-affinity IgE receptors (FcεRI) on their surface, they can capture circulating IgE. IgE-bound mast cells degranulate large amounts of histamine, heparin, and proteases when they encounter antigens. As IL-33 is an important mediator of innate immunity and mast cells play an important role in adaptive immune responses, interactions between the two could link innate and adaptive immunity. IL-33 promotes the adhesion of mast cells to laminin, fibronectin, and vitronectin. IL-33 increases the expression of adhesion molecules, such as intracellular adhesion molecule-1 and vascular cell adhesion molecule-1, in endothelial cells, thus enhancing mast cell adhesion to blood vessel walls. IL-33 stimulates mast cell proliferation by activating the ST2/Myd88 pathway; increases mast cell survival by the activation of survival proteins such as Bcl-XL; and promotes the growth, development, and maturation of mast cell progenitors. IL-33 is also involved in the activation of mature mast cells and production of different proinflammatory cytokines. The interaction of IL-33 and mast cells could have important clinical implications in the field of clinical urology. Epithelial dysfunction and mast cells could play an important role in the pathogenesis of interstitial cystitis. Urinary levels of IL-33 significantly increase in patients with interstitial cystitis. In addition, the number of mast cells significantly increase in the urinary bladders of patients with interstitial cystitis. Therefore, inhibition of mast cell activation and degranulation in response to increase in IL-33 is a potential therapeutic target in the treatment of interstitial cystitis.
장태영,박선기,김규성,정동학 대한비과학회 2000 Journal of rhinology Vol.7 No.1
Background and Objectives:Correct diagnosis for allergic rhinitis is important for optimal management. A thorough historyshould be taken, followed by general and endoscopic examinations and confirmatory investigations. The role of diagnostic testsin the evaluation of patients with allergic rhinitis continues to evolve. This clinical study was performed to identify the relationshipbetween clinical history and diagnostic tests. Materials and Methods:Questionnaire surveys for clinical history, skin test, RAST,and nasal provocation test (acoustic rhinometry and symptom score) to the house dust mites (Dermatophagoides pteronyssinus)were performed in 100 patients from July, 1996 to August, 1998 at Inha University Hospital. The relationship between clinicalhistory (change of syagoides pteronyssinus antigen (Allergopharma, Reinbeck, USA) was sprayed and 15 with PC-SAS. (ver6.120) Results:There was no correlation between clinical history and the diagnostic tests. However there was a correlationbetween the results of either skin or RAST testing and those of nasal provocation test. Conclusions:More careful and completehistory taking is needed for diagnosis of allergic rhinitis. The combined use of RAST, skin testing and nasal provocation testyields more information.
만성 부비동염 환자에서의 중비도와 상악동의 배양균주의 연관성
장태영,신준순,최윤석 대한이비인후과학회 2004 대한이비인후과학회지 두경부외과학 Vol.47 No.5
Background and Objectives:The identification of specific pathogens for chronic sinusitis is important for antibiotic treatment. middle meatal cultures can replace maxillary sinus cultures as a noninvasive alternative. Materials and Method:Twenty-two patients with chronic sinusitis, who didnt respond to medical therapy and recieved endoscopic sinus surgery were selected. We collected preoperative middle meatal samples and intraoperative maxillary sinus samples from twenty two patients under end-oscopic visualization using strile cotton swabs. Results:In 18 of the 22 samples (82% )correlated well with the intraoperative maxillary sinus cultures. In both middle meatus and maxillary sinus samples, most frequently encountered microorganism was Staphylococus aureus. Conclusion:Noninvasive middle meatal cultures correlate well with maxillary sinus cultures, and can be confidently used as an alternative.
장태영,이승준,김경태,최윤석 대한이비인후과학회 2005 대한이비인후과학회지 두경부외과학 Vol.48 No.3
Background and Objectives:Postoperative mucocele of the maxilary sinus occurs as a delayed complication folowing Cald-wel-Luc operation. Traditionaly, the need for complete removal of sinus mucocele has been emphasized; in the more recent investigate the results of endoscopic surgery and Caldwell-Luc operation in managing postoperative mucocele of the maxillary sinus. Subjects and Method:We reviewed 36 patients diagnosed as postoperative mucocele of the maxillary sinus from June 1996 to June 2002. Nineteen patients were treated by endoscopic approach and 17 patients by Caldwell-Luc operation. We compared the endoscopic approach with Caldwell-Luc operation with respect to differences in pre-operative symptoms and post-operative symptoms, hospitalization period, morbidity, operation time. Results:We could manage patients of medial type and some cases of lateral type by using the endoscopic approach, and anterior lateral or inferior lateral type and complicated cases by Caldwell-Luc approach . There were no diferences in symptom changes and recurrence rate betwen endoscopic approach group and Caldwell-Luc approach group. There were no significant complications in both groups. Conclusion:The selection of an on of the maxillary sinus mucocele. (Korean J Otolaryngol 205 ;48 :314-9)