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과민성 대장염환자에서 이중 맹검 투여한 Tiropramide의 치료 효과
정규원(Kyu Won Chung),선희식(Hee Sik Sun),김부성(Boo Sung Kim),정인식(In Sik Chung),최명규(Myung Gyu Choi),최규용(Gyu Yong Choi),박수헌(Soo Heon Park),장창훈(Chang Hoon Jang),한준열(Jun Yeul Han) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5
N/A A double-blind, randomized parallel group trial comparison study was performed in 63 patients with irritable bowel syndrome for evaluation of effectiveness and safety of Tiropramide. Over a treatment period of 4 weeks, Tiropramide (300 mgjday) were administered in 32 patients and placebo in 31 patients with irritable howel syndrome. The degrecs of symptom scores for abdominal pain, belching, flatulence, diarrhea, abdominal discomfortnesi, inadequate defecation, borborygmi, etc were assessed every week by interview of pat:ient.s during the treatment. At the end of the four week. treatment, 78.2% of the treatment group with Tiropramide and 40.5% of placebo group were markedly improved their symptoms. The degrees of symptom scores for abdominal pain, inconiplete evacuation, borborygmi, flatulence, abdominal distension, and intensity of nausea showed significant improvement in the treatment group compared with placebo group in each week assessrnent. One patient with Tiropramide treatment and two patients of placebo group experiencecl aggravation of symptoms during treatment but no one had adverse reaction during treatment. These results suggest that Tiropramide is effective and safe for the treatment of irriitable bowel syndrome.
Flat Corrugated Plate의 강성에 대한 이론 및 실험적 연구
장창훈 울산과학대학 1992 연구논문집 Vol.17 No.-
Flat Corrugated Plate를 등가 강성을 갖는 직교 이방성판으로 치환시켜 해석하는 이론식을 유도하였다. 고유 진동수 측정을 통한 주름판의 강성을 산정하여 이론식의 타당성의 입증을 시도하였다. 굽힘강성의 경우는 이론, 실험치가 잘 접근하여 이론의 타당성이 입증되었으나, 비틀림 강성의 경우는 큰 오차를 내거나 실험 산정이 불가능하여 입증하지 못하였다. The correlative-expression of moment with curvature is derived for In order to check the validity of this expression, the rigidity measured by vibration method and theoretical values are compared. For bending rigidity, the theoretical values are in good agreement with the measured values: for torsional rigidity, this expression's applicability is proved to be very weak.
韓秉基,張昌訓 弘益大學校 1985 弘大論叢 Vol.17 No.2
A new structural model is presented for the analysis of the rigidity of eccentrically stiffened plate with rectangular cross-sectional stiffeners. The following postulations are employed for the derivation of rigidity: (1) The orthogonally stiffened plate element is constructed of two parts; the secured part composed of stiffener and plate attached to the stiffener, and the pure plate part without stiffener. (2) The continuity condition should be satisfied at the interface between the secured part and the plate part to from them into a monolithic structure. Several existing theories for the rigidity of stiffened plates are computed and compared with the present theory. In the present theory, the bending rigidity are almost same with the existing theories. The torsional rigidity, however, shows significant difference between present theory and existing theories. The experiment on the torsional rigidity is performed to check the accuracy of the theories. By the result the present theory shows the good accuracy for the torsional rigidity.
이덕영,장창훈 울산과학대학 1992 연구논문집 Vol.17 No.-
사각형 공간의 고유 진동수 및 음향 모우드 해석을 위하여, 20절점의 등계수 육면체 요소를 이용한 유한요소 프로그램을 개발하고, 그 정확성을 확인하고자 직육면체 방에 적용하여 이론 고유 진동수 값과 수치 해석 고유 진동수 값을 비교 검증하였다. In this paper, a numerical computer program[CANMAP3D] using a twenty node, isoparametric acoustic finite element is developed for analysing the natural frequencies and acoustic modes of an irregularly shaped enoclosure. The numerical results of the developed program is checked with the exact solution results applied to a rectangular shaped room. The finite element analysis of the model shows very good agreement with the exact solution.
주름잡힌 板의 剛性에 대한 理論解析과 實驗的 硏究(山型)
韓秉基,張昌訓,宋東浩 弘益大學校 1986 弘大論叢 Vol.18 No.2
In this paper, the triangular-wave type corrugated plate, which is a kind of the stiffened plate-structures for increasing the load-carrying ability and optimizing the economy, is investigated. On the base of small displacement theory, analysis method for the theoretical investigation of such a plate is proposed, and using the aluminium specimen which is bend-formed to triangular-wave type, four point bending experiment and three point supporting-one point loading torsional experiment are carried out. Good experimental confirmation of the validity of the proposed analysis method is found.
단일 유연 링크 매니퓰레이터에서의 시간 분리에 따른 복합제어기의 성능
장창훈,이동욱,이수한 울산대학교 1995 공학연구논문집 Vol.26 No.2
싱귤라 퍼터베이션 기법은 유연 링크 매니퓰레이터와 유연 조인트 로봇의 제어기 설계에 널리 적용되고 있다. 싱귤라 퍼터베이션 기법을 이용하여 제어기를 설계하는데 있어서, 빠른 제어기의 대역폭은 느린 제어기의 대역폭 보다 세배 이상 커야 한다고 경험적으로 알려져 있다. 그러나, 본 연구에서는 제어성능을 유지하기 위하여는 주어진 몇 가지 조건하에서 O(ε)모델의 경우는 8배 이상 분리되어야 하고, O(ε²)모델의 경우 4배 이상 분리되어야 함을 보였다. The singular perturbation technique is widely applied for the controller design of flexible link manipulator and flexible joint robot. In designing the controller, it has been thought as a rule of thumb that the bandwidth of a fast controller should be 3times larger than those of a slow controller. The result of this paper, however, shows the separation should be 8 times for O(ε) model and 4 times for O(ε²) model under some conditions for keeping the designed performance.
인공 승모판 대치술후 정식도 심초음파도로 발견된 좌심방 혈전의 치험 1예
양종목,장창훈,백상홍,정욱성,전승석,최규보,홍순조 대한내과학회 1992 대한내과학회지 Vol.42 No.4
1) 경식도 심초음파도는 경흉부 심초음파도로는 잘 보이지 않은 좌심방의 이상을 잘 볼 수 있다. 2) urokinase는 새롭게 생긴 혈전의 용해에 유용할 것으로 사료된다. Thrombi located in the left atrial appendage (=LAA) are frequently not detected with conventional two dimensional echocardiography (=TTE). The transesophageal echocardiographic (TEE) approach readily visualizes left atrial morphology and may be used a s an alternative. We report a case of LAA thrombus detected by TEE but not TTE. The patient was treated with Saint Jude Medical prosthetic valve (31 mm) for severe mitral stenosis and moderate mitral regurgitation. Thereafter LAA thrombus was detected by TEE. Intravenous urokinase was used. But right distal popliteal arterial obstruction was developed during intravenous urokinase infusion. Intraarterial urokinase was used. LAA thrombus was disappeared, and right distal popliteal arterial obstruction was partially lysed. The results were as follows: 1) Left atrial thrombi, which was not visualized by TTE, were detected by TEE. 2) Urokinase was useful for newly formed thrombus.