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바 피개의치를 이용한 쇄골두개이형성증 환자의 치료: 증례보고
장중희,송민석,김현민,김남훈,엄민용,구현모,이준규,정종철,김세웅,Jang, Jung-Hui,Song, Min-Seok,Kim, Hyeon-Min,Kim, Nam-Hun,Eom, Min-Yong,Koo, Hyun-Mo,Yi, Jun-Kyu,Jeong, Jong-Cheol,Kim, Se-Woong 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.1
Cleidocranial dysplasia is rare inherited skeletal dysplasia. It was first reported by Martin in 1765. Subsequently, Marie and Sainton independently documented the criteria of the disease. Cleidocranial dysplasia is a bone disorder caused by a defect in the CBFA1 gene of chromosome 6p21. This gene guides osteoblastic differentiation and appropriate bone formation. Patient with cleidocranial dysplasia has maxillary deficiency, high and narrow palate, prolonged retention of primary teeth, unerupted permanent teeth and supernumerary teeth. Therapeutic options in these patients include of autotransplantation of selected impacted teeth, forced eruption of permanent teeth, full denture, overdenture and implant-supported prosthesis. We report a patient with cleidocranial dysplasia. This patient was treated with implant supported bar overdenture. Despite of gene defect that affects osteoblastic activity, bone remodeling and osseointegration occurred in our patient. So, we report this case with review of literature.
바 피개의치를 이용한 쇄골두개이형성증 환자의 치료: 증례보고
장중희,송민석,김현민,김남훈,엄민용,구현모,이준규,정종철,김세웅,Jang, Jung-Hui,Song, Min-Seok,Kim, Hyeon-Min,Kim, Nam-Hun,Eom, Min-Yong,Koo, Hyun-Mo,Yi, Jun-Kyu,Jeong, Jong-Cheol,Kim, Se-Woong 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.2
Cleidocranial dysplasia is rare inherited skeletal dysplasia. It was first reported by Martin in 1765. Subsequently, Marie and Sainton independently documented the criteria of the disease. Cleidocranial dysplasia is a bone disorder caused by a defect in the CBFA1 gene of chromosome 6p21. This gene guides osteoblastic differentiation and appropriate bone formation. Patient with cleidocranial dysplasia has maxillary deficiency, high and narrow palate, prolonged retention of primary teeth, unerupted permanent teeth and supernumerary teeth. Therapeutic options in these patients include of autotransplantation of selected impacted teeth, forced eruption of permanent teeth, full denture, overdenture and implant-supported prosthesis. We report a patient with cleidocranial dysplasia. This patient was treated with implant supported bar overdenture. Despite of gene defect that affects osteoblastic activity, bone remodeling and osseointegration occurred in our patient. So, we report this case with review of literature.
NR, SBR, BR 가황물의 원형 변형으로부터의 회복 거동
장중희 ( Joong Hee Jang ),최성신 ( Sung Seen Choi ) 한국고무학회 2009 엘라스토머 및 콤포지트 Vol.44 No.4
충전제의 영향을 막기 위해 비보강 NR, BR, SBR 고무 가황물을 원형 변형시켜 노화시킨 후 회복 거동을 비교하였다. 시료는 상온, 50, 70, 90 ℃에서 10일간 노화시켰다. 측정 시간이 증가함에 따라 회복률은 증가하였다. 노화 후 측정 시간에 따른 회복률의 변화로부터 1.0 초 미만의 순간회복률을 구하였다. 상온 노화에서는 노화 기간이 짧아 고무 간의 회복률 차이가 거의 나타나지 않았다. 하지만 50, 70, 90 ℃에서의 가속 노화 실험 결과에서는 각 고무 간의 회복률 차이가 뚜렷하게 나타났다. BR의 회복률이 가장 우수하였고, SBR의 회복률이 가장 적었다. 그러나 90 ℃ 가속 노화 에서는 NR의 회복률이 BR보다 높게 나타났다. 노화 온도가 높아 질수록 초기 회복률이 감소하였으며, 그 감소 폭은 SBR이 가장 크게 나타났다. 실험 결과는 고무의 반발 특성과 노화에 의한 가교밀도 변화로 설명하였다. Recovery behaviors of unfilled NR, BR, and SBR vulcanizates after aging with a circular deformation were compared to prevent the influence of reinforcing agent. Samples were aged at room temperature, 50, 70, and 90 ℃ for 10 days. Recovery increased by increasing the measurement time. Instantaneous recoveries less than 1.0 sec were obtained using the recovery variations with the measurement time. For aging at room temperature, difference in the recoveries of the rubber samples was not significant because the aging time was too short. However, for accelerated thermal aging at 50, 70, and 90 ℃, difference in the recoveries of the rubber samples was significant. Degree of recovery of BR specimen was higher than those of the others, while that of SBR was lowest. However, for accelerated thermal aging at 90 ℃, recovery of the NR sample was higher than that of the BR one. The initial recovery decreased by increasing the aging temperature and the decrement of SBR was larger than the others. The experimental results were explained with the resilience properties of rubbers and the crosslink density changes by thermal aging.
Influence of Aging Medium on Recovery Behaviors of CR/NR Composite from Circular Deformation
최성신,장중희,임송희 한국고분자학회 2010 Macromolecular Research Vol.18 No.4
This study examined the recovery behavior from the circular deformation of a thermally aged CR/NR composite. A linear sample of a rubber vulcanizate was made into circular form by fixing both ends of the sample with a pin and aging it thermally in air and distilled water. The recovery increased with the time after removal from circular deformation. The recovery decreased with increasing aging temperature and time. Recovery of the sample aged in air was smaller for long measurement times than that of the sample aged in distilled water. The difference in the recovery behavior of the samples aged in air and distilled water can be explained by changes in the crosslinking density and the annealing effect of the aging medium. The instantaneous recovery was obtained by extrapolating the linear recovery variations. They also showed a good linear relationship with the aging time. The recovery behavior at ambient temperature could be predicted using the experimental results of the accelerated thermal aging. In terms of the instantaneous time, it was predicted that the service lifetime of the sample aged in air at ambient temperature would be much longer than the sample aged in water.
Andre Ricard,오수기,장중희,김유권 한국물리학회 2015 Current Applied Physics Vol.15 No.11
The N2 and Ar-20%N2 RF plasmas and afterglows have been generated in a quartz tube under a flowing condition maintained at 6e8 Torr and a flow rate of 0.5e0.6 slm. The detailed emission characteristics of active species have been analyzed by emission spectroscopy. Under such conditions, the plasma rotational temperature increases from 400 to 800 K with increasing RF powers from 50 to 130 W, while the characteristic vibrational temperature remains at about 104 K. The densities of active species (N, N2(A), N2(X, v > 13) and Nþ 2 ) in the afterglow are measured to be in the order of ~1015, ~1011, ~1014 and ~1010 cm3, respectively. In addition, the following characteristics of the afterglows are noted: First, the same densities of the active species can be obtained at lower RF powers (20-50 W) for Ar-20%N2 than for pure N2 which requires higher RF powers (50-100 W). Second, the ionization degree of N+ 2 =N2 in the plasma increases readily to a saturation value at a lower RF power of 50 W for Ar-20%N2, whereas in the afterglow, the absolute density of Nþ 2 is further reduced below 109 cm-3.
박봉욱,하영술,김진현,조희영,정명희,김덕룡,김욱규,김종렬,장중희,변준호,Park, Bong-Wook,Hah, Young-Sool,Kim, Jin-Hyun,Cho, Hee-Young,Jung, Myeong-Hee,Kim, Deok-Ryong,Kim, Uk-Kyu,Kim, Jong-Ryoul,Jang, Jung-Hui,Byun, June-Ho 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.4
Purpose: Adipose tissue is located beneath the skin, around internal organs, and in the bone marrow in humans. Its main role is to store energy in the form of fat, although it also cushions and insulates the body. Adipose tissue also has the ability to dynamically expand and shrink throughout the life of an adult. Recently, it has been shown that adipose tissue contains a population of adult multipotent mesenchymal stem cells and endothelial progenitor cells that, in cell culture conditions, have extensive proliferative capacity and are able to differentiate into several lineages, including, osteogenic, chondrogenic, endothelial cells, and myogenic lineages. Materials and Methods: This study focused on endothelial cell culture from the adipose tissue. Adipose tissues were harvested from buccal fat pad during bilateral sagittal split ramus osteotomy for surgical correction of mandibular prognathism. The tissues were treated with 0.075% type I collagenase. The samples were neutralized with DMEM/and centrifuged for 10 min at 2,400 rpm. The pellet was treated with 3 volume of RBC lysis buffer and filtered through a 100 ${\mu}m$ nylon cell strainer. The filtered cells were centrifuged for 10 min at 2,400 rpm. The cells were further cultured in the endothelial cell culture medium (EGM-2, Cambrex, Walkersville, Md., USA) supplemented with 10% fetal bovine serum, human EGF, human VEGF, human insulin-like growth factor-1, human FGF-$\beta$, heparin, ascorbic acid and hydrocortisone at a density of $1{\times}10^5$ cells/well in a 24-well plate. Low positivity of endothelial cell markers, such as CD31 and CD146, was observed during early passage of cells. Results: Increase of CD146 positivity was observed in passage 5 to 7 adipose tissue-derived cells. However, CD44, representative mesenchymal stem cell marker, was also strongly expressed. CD146 sorted adipose tissue-derived cells was cultured using immuno-magnetic beads. Magnetic labeling with 100 ${\mu}l$ microbeads per 108 cells was performed for 30 minutes at $4^{\circ}C$ a using CD146 direct cell isolation kit. Magnetic separation was carried out and a separator under a biological hood. Aliquous of CD146+ sorted cells were evaluated for purity by flow cytometry. Sorted cells were 96.04% positivity for CD146. And then tube formation was examined. These CD146 sorted adipose tissue-derived cells formed tube-like structures on Matrigel. Conclusion: These results suggest that adipose tissue-derived cells are endothelial cells. With the fabrication of the vascularized scaffold construct, novel approaches could be developed to enhance the engineered scaffold by the addition of adipose tissue-derived endothelial cells and periosteal-derived osteoblastic cells to promote bone growth.
Midfacial degloving approach를 이용한 중안면 골절 환자의 치험례
김현민(Hyeon-Min Kim),정종철(Jong-Cheol Jeong),송민석(Min-Seok Song),장중희(Jung-Hui Jang),김남훈(Nam-Hun Kim) 대한구강악안면외과학회 2005 대한구강악안면외과학회지 Vol.31 No.1
In 1974, Casson et. al. reported midfacial degloving approach to repair the midfacial bone fracture. After then, this approach has been used frequently to treat the lesions on nasal cavity, nasopharynx, facial plastic surgery and midfacial trauma. Midfacial degloving approach consists of 1) bilateral sublabial incision 2) complete transfixion incision/ septocolumellar incision 3) bilateral intercartilaginous incision 4) bilateral pyriform aperature incision. This approach provides proper access for midfacial bone structure without facial scar but has post-operative complications such as transient epistaxis, infraorbital nerve paresthesia and nasal crust. We treated three patients using midfacial degloving approach to correct traumatic deformity in midface area. In two patients, rhinoplasty with autogenous rib graft was done simultaneously. So we report these cases with review of literatures.