지역사회 저소득 취약계층 주민을 위한 1년간의 운동프로그램이 대사 및 심혈관 건강 위험요인에 미치는 영향

장재승 중앙대학교 학교체육연구소 2024 Asian Journal of Physical Education of Sport Scien Vol.12 No.2

본 연구는 지역사회 저소득층 성인 주민 34명(남:6, 여:28, 47.3±9.5세)을 대상으로 12개월의 운동 증진 프로그램이 대사증후군 및 심혈관 건강 위험요인에 미치는 효과를 규명하기 위해 수행되었다. 주 3회 운동프로그램은 60분 내외의 수영, 요가, 복합운동(유산소+저항운동)을 각각 1회씩 실시하도록 구성되었고 운동자각도를 기준으로 가벼움부터 힘듦의 운동강도로(rating of perceived exertion, RPE 12-16), 준비운동 및 정리운동과 함께 실시하였다. 연구 결과 전반적인 체력 수준의 향상과 함께 체중, 체질량지수, 체지방율, 내장 및 피하지방량에서 유의한 개선이 관찰되었다. 임상 화학 검사 결과로는 공복 시 혈중 인슐린수준(p=0.042)과 homeostasis model assessment-estimated insulin resistance (HOMA-IR)(p=0.03)이 유의하게 개선되었지만, 혈청 지질 및 지단백질은 유의한 변화가 나타나지 않았다. 안정 시 심박수(p=0.004)와 심근 부담률(p=0.034)을 포함한 혈역학적 변인이 유의하게 개선되었다. 특히, 대사증후군 구성요소(p=0.017)와 Framingham 위험 지수(p=0.016)에서 유의한 감소가나타났으며, 이는 운동프로그램이 심혈관질환 위험 요소를 완화하고 심혈관 건강을 개선하는 데 효과적임을 시사한다. This study was conducted to investigate the effects of a 12-month exercise promotion program on metabolic syndrome and cardiovascular health risk factors among 34 low-income adult residents (6 men, 28 women, 47.3±9.5 years old) in a community. The exercise program, held three times a week, consisted of about 60-minute sessions of swimming, yoga, and combined exercise (aerobic+resistance exercises), each performed once a week with varying intensities from light to hard (rating of perceived exertion, RPE 12-16), including warm-up and cool-down sessions. The results showed significant improvements in overall physical fitness levels, weight, body mass index, body fat percentage, and visceral and subcutaneous fat mass. Clinical chemistry tests revealed significant improvements in fasting blood insulin levels (p=0.042) and homeostasis model assessment-estimated insulin resistance (HOMA-IR) (p=0.03), but no significant changes were observed in serum lipids and lipoproteins. Hemodynamic variables, including resting heart rate (p=0.004) and myocardial load (p=0.034), were significantly improved. Notably, there was a significant reduction in the components of metabolic syndrome (p=0.017) and the Framingham risk score (p=0.016), suggesting that the exercise program is effective in mitigating cardiovascular disease risk factors and improving cardiovascular health.

Differences in the Survival of Gastric Cancer Patients after Gastrectomy according to the Medical Insurance Status

장재승,신동규,조혜민,권유진,조동휘,이경복,박상수,윤진,장용석,김일명 대한위암학회 2013 Journal of gastric cancer Vol.13 No.4

Purpose: In Korea, the entire population must enroll in the national health insurance system, and those who are classified as having a lower socioeconomic status are supported by the medical aid system. The aim of this study was to evaluate the association of the medicalinsurance status of gastric cancer patients with their survival after gastrectomy.Materials and Methods: A total of 247 patients who underwent surgical treatment for gastric cancer between January 1999 and December2010 at the Seoul Medical Center were evaluated. Based on their medical insurance status, the patients were classified into two groups: the national health insurance registered group (n=183), and the medical aid covered group (n=64). The survival rates were calculated using the Kaplan-Meier method.Results: The median postoperative duration of hospitalization was longer in the medical aid covered group and postoperative morbidity and mortality were higher in the medical aid group than in the national health insurance registered group (P<0.05). The overall 5-year survival rate was 43.9% in the medical aid covered group and 64.3% in the national health insurance registered group (P=0.001).Conclusions: The medical insurance status reflects the socioeconomic status of a patient and can influence the overall survival of gastric cancer patients. A more sophisticated analysis of the difference in the survival time between gastric cancer patients based on their socioeconomicstatus is necessary.

CAD/CAM으로 제작한 점막하 지르코니아 임플란트 보철 수복 증례

장재승,김선재,Chang, Jae-Seung,Kim, Sunjai 대한치과보철학회 2014 대한치과보철학회지 Vol.52 No.4

최근 지르코니아와 CAD/CAM을 이용하는 심미적인 임플란트 보철치료 방법들이 많이 소개되고 있다. 그러나 이러한 방법들은 치은부위와 교합면부위에서 한계점들을 가지고 있다. 이에 본 증례에서는 지르코니아와 CAD/CAM 시스템을 이용하여 고정체 1 mm 상부에서부터 형성되는 점막하지르코니아 임플란트 보철물을 제작하고 이를 타이타늄 지대주와 접착하여 시멘트 나사 유지형 보철물을 제작하였다. 임상적으로 심미적이고 기능적면에서 만족할 만한 결과를 얻었기에 이를 보고하고자 한다. They have been recently introduced many aesthetic implant prosthesis using with zirconia and CAD/CAM. However, there are many limitations in their gingival and occlusal region. In this case, submucosal zirconia implant prosthesis were fabricated with CAD/CAM system. The connection of these screw cement retained prosthesis and titanium abutment was designed to 1mm above the fixture. The clinical results were satisfactory on the aesthetics and function.

임상연구의 설계 및 연구윤리

장재승,이선이,하태현,윤인영,하규섭,Chang, Jae Seung,Lee, Sunny,Ha, Tae Hyon,Yoon, In-Young,Ha, Kyooseob 대한생물정신의학회 2012 생물정신의학 Vol.19 No.4

Data from clinical studies are needed for psychiatrists to make quick and scientific decisions based on the best available evidence in clinical settings. Various methods of clinical studies are useful for clinicians to have reliable answers to unmet clinical needs. Although randomized controlled trials may provide high-quality information about major issues, well-designed, naturalistic and observational studies often give us unbiased explanation for real-world phenomena. Adequate selection of clinical variables and appropriate number of participants are key factors of well-designed clinical studies. Statistical methods can add an extra dimension to initial design of clinical studies. Given ethical issues in clinical studies on psychiatric disorders, special regards should be paid to participants' ability to provide informed consents. New strategies of clinical studies need to be developed to meet clinical needs and protect the rights and welfare of study participants.

치료저항성 주요우울장애 환자의 라모트리진 강화요법: 자연관찰연구

장재승,조수현,차보석,문은수,하태현,윤인영,하규섭 대한정신약물학회 2008 대한정신약물학회지 Vol.19 No.5

Objective:Lamotrigine’s possible efficacy in the treatment of depressive disorders has been suggested. This naturalistic study investigated clinical response to lamotrigine augmentation in patients with treatment-resistant depression. Characteristics of the lamotrigine-responders were also explored. Methods:Clinical data from 40 lamotrigine- treated patients with treatment-resistant unipolar depression were analyzed. The subjects were diagnosed with DSM-IV major depressive disorder and resistant to at least 2 antidepressants. Efficacy of lamotrigine treatment was measured by the changes in mean scores of the Clinical Global Impression Severity subscale (CGI-S), which were extracted from the prospective mood chart and structured interviews. Response was defined as a decrease of at least 2 or more from baseline on the CGI-S. Untoward effects associated with lamotrigine treatment were also assessed through medical records. Results:Significant reduction in the CGI-S mean score was observed from baseline through 8 week lamotrigine augmentation in 40 patients with treatment-resistant unipolar depression (t=5.7, df=39, p<.01), and the magnitude of treatment effect was large (reffect size=0.68). Drop-outs were mainly attributable to lamotrigine-associated rash (N=5). Greater rate of improvement was associated with responder group (N=14) compared to non-responder group (N=17) from week 3 onward. Conclusion:The results of current study lend support to the potential benefit of lamotrigine augmentation in a subpopulation of patients with treatmentresistant unipolar depression. Continuation of lamotrigine add-on for more than 3 weeks may be needed to assess clinical outcome. Lamotrigine augmentation was generally well-tolerated. Large scale, double-blind studies are necessary to confirm its use as an augmentation agent. 이번 연구는 임상 실제에서 치료저항성 주요우울장애 환자를 대상으로 8주 라모트리진 강화요법의 유용성을 평가한 자연경과연구이다. 전체 대상군에서 8주간 치료 후 유의한 우울증상의 호전이 관찰되었고, 반응군과 비 반응군 간 임상증상 변화양상은 3주 이후 유의하게 구분 되었다. 라모트리진 강화요법의 안전성도 관찰되었다. 라 모트리진 강화요법의 임상효능과 반응군의 특성을 밝히 기 위하여 대규모 전향적 통제연구가 필요하다.

다층 구조의 4,7-diphenyl-1, 10-phenanthroline과 tris(8-hydroxyquinoloine) Aluminum 전자수송층을 이용한 유기발광소자의 효율 증진 메카니즘

장재승,김대훈,이광섭,김태환 한국진공학회 2012 한국진공학회 학술발표회초록집 Vol.2012 No.2

정신분열병 환자의 항정신병약물 치료과정에서 나타나는 언어성 환청의 다차원적 변화

장재승,정성훈,안용민,김용식 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.1

Objectives : Auditory verbal hallucination (AVH) is knoun for its high prevalence and difficulty in evaluation. Authors hypothesized that it may be possible to find useful dimensions of AVH that reflect the clinical status of schizophrenic patients by assessing the multi-dimensional changes and linguistic forms' of AVH during antipsychotic treatment. Methods : 33 schizophrenic patients with AVH were selected and periodically assessed with the 11 items of hallucinations subscale of 'The Psychotic Symptom Rating Scales (PSYRATS)'. In addition, to assess the linguistic forms observed in the AVH, the evaluations of sentence structure of AVH reported by the patients were conducted. Results : PSYRATS showed the multidimensionality inherent in AVH. The changes in the quantitative dimensions did not correlate well with patients' subjective distress. However, qualitative changes in the cognitive and emotional dimensions showed more favorable correlation with clinical course of the patient. The sentence structures of AVH showed tendency to change from "sentence" to "non-sentence" type with overall improvement during treatment. Conclusion : Multi-dimensional approach to AVH can give us more information about the changing patterns of multi-fa-ceted structure of AVH and clinical status of patients than one-dimensional or categorical approach.

혼합 형광체를 사용하여 제작한 백색 유기발광소자의 전기적 및 광학적 특성

장재승,김대훈,김태환 한국진공학회 2013 한국진공학회 학술발표회초록집 Vol.2013 No.2

냉각속도가 지르코니아-도재 수복물의 전장도재 내 잔류응력에 미치는 효과에 관한 문헌고찰

장재승,김선재,Chang, Jea-Seung,Kim, Sunjai 대한치과보철학회 2014 대한치과보철학회지 Vol.52 No.2

최근 많이 이용되고 있는 지르코니아-도재 수복물은 그 적용범위가 점차로 증가하고 있다. 임상연구결과에서 지르코니아 코어는 매우 높은 성공율을 보이고 있으나 코어 위에 축성되는 전장도재는 기존에 이용되어온 금속-도재 수복물에 비해 높은 파절빈도를 나타내고 있다. 이러한 파절의 원인으로 여러가지 요소가 거론되고 있으나 아직 명확하게 설명하고 있지는 못하다. 최근 전장도재 축성 후 냉각과정에서 잔존하는 잔류응력이 전장도재의 파절에 영향을 미칠 수 있다는 연구결과가 속속 발표되고 있다. 본 고찰에서는 잔류응력이 무엇이며 도재 축성 후 냉각과정에서 어떤 기전을 통해 전장도재 내에 잔류응력이 발생하는지, 또한 기존의 금속-도재 수복물에서 발생하는 잔류응력과는 어떤 차이가 있는지 문헌고찰을 통해 살펴보고자 한다. Nowadays, dental zirconia is widely used as a framework material for a fixed dental prosthesis as well as a single restoration. However, clinical studies have reported high incidence of veneer chipping of zirconia-ceramic restorations compared to that of metal-ceramics. Several factors were raised as the possible causes of veneer ceramic chipping, however, it is still in debate. Recently, residual stresses in the veneer ceramics after cooling process gathers attention as one possible cause of chipping and many studies reported that the rate of cooling significantly influenced the types and the amount of residual stress. The purpose of current review was to briefly describe the effect of cooling rate on the residual stress in zirconia-ceramics. It was also described that the different behavior of residual stress between zirconia-ceramics and metal-ceramics following different cooling rate.

틸팅열차 운용효율화 방안 연구

장재승(Jang Jae-Seung),정도원(Jung Do-Won),김명수(Kim Myeong-Su),원용환(Won Yong-Hwan),서예원(Seo Ye-Won) 한국철도학회 2009 한국철도학회 학술발표대회논문집 Vol.2009 No.11월

KORAIL is planning to induce EMU(Electric Multi Unit) at the speed of 180㎞/h as an alternative of Saemaeul train(PP;Push-Pull) which is disappearing in 2012 according to the crapped trains out of date and the development of the area around Yong San train station. Accordingly, Korean Tilting Train eXpress(TTX) localized in 2013 has achieved the operation test of 100,000 ㎞ non-accident safely so far, and is continuously scheduled to go through an efficiency test and improvement of train in the future. This study scrutinized the proper manufacture settings of train by making preparation for TTX' import and operation, the whole economy efficiency by analyzing the operational cost such as operating revenue, labor cost, maintenance cost, and power equipment cost in accordance with the introduction of TTX. Therefore, we'd like to maximize the effectiveness of importation and operation of TTX by performing the study on decreasing the operation cost when TTX is working on.