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      • 극하근과 대원근에 적용한 전침이 견관절 기능 개선 및 통증 경감에 미치는 영향

        장원석,배성수,Jang, Won-Seok,Bae, Sung-Soo 대한물리치료학회 2007 대한물리치료학회지 Vol.19 No.6

        Purpose: This study examined the effect of electro-acupuncture stimulation of the infraspinatus and teres major on the shoulder function reduction. The subjects consisted of 20 female patients with a shoulder dysfunction. Methods: The 20 female patients with shoulder dysfunction participated voluntary in this research. 10 minute electro-acupuncture stimulation (frequency: 5Hz, Intensity: below the pain threshold) with Infra-red therapy, 3 times per week given to the patients' Trigger point of the infraspinatus and teres major. The Visual Analog Scale (VAS), Apley's Scratch Test and Global Perceived Effect Scale (GPES) were examined before alter six applications. Results: There was a significant decrease in the VAS (p<0.05) and Apley's Scratch Test (p<0.05). In addition, there was statistically significant increase in the Global Perceived Effect Scale (p<0.05). Therefore, the infraspinatus and teres major is a very important muscle for the shoulder function. Conclusion: This data will be used to develop a treatment method for patients with a shoulder dysfunction. These results suggest that the electro-acupuncture stimulation into the infraspinatus and the teres major Trigger point is an effective intervention for patients with shoulder dysfunction and pain.

      • KCI등재후보

        난소 절제 백서에서 17β-Estradiol 투여가 골조직에 미치는 영향

        장원석,김종렬,박봉수,성일용 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.4

        This study was focused on the changes of mineral density and histopathologic features of osseous tissue when ovariectomized rats were administered with 17β-Estradiol. Forty-eight rats, 11 weeks of age, were divided into four groups, which are a normal control group, an ovariectomized control group, an experimental group 1 which was given 17β-estradiol immediately after the ovariectomy and an experimental group 2 which was given 17β-Estradiol 3 weeks after the ovariectomy. They were sacrificed at different time intervals (1, 3, 4 and 8 weeks) for histopathologic observation, histo-morphometric analysis and immunohistochemistry with fibronectin and CD34 antibody. Most rats showed the increase in bone density, which was the least in the ovariectomized control group. In histopathologic features of both the mandible and the tibia, the osteoclasts in bone marrow increased in the ovariectomized control group of more than 3 weeks. In histomorphometric analysis, the osteoclasts increased in both the mandible and the tibia in length of time. In comparison of the increase of osteoclast between four groups, it decreased as following order: the ovariectomized control group, the expermiental group 2 the experimental group 1, the normal control group. Especially the experimental group 1 and experimental group 2 at 4 weeks showed remarkable changes both in the mandible and in the tibia in comparison with the ovariectomized control group. In immunohistochemical anaylsis with fibronectin, the more week-ovariectomized control groups of both the mandible and the tibia showed weaker fibronectin expression in osteoblast and bone marrow. Among the experimental group 1 and 2, 4-week group showed the strongest expression. In immunohistochemical analysis with CD34, the mandible showed generally weak expression but 8-week experimental group 1 and 2 showed relatively moderate expression in osteoblast and bone marrow. In case of the same groups of tibia, 4-week group show the strongest expression. With all these results, it is assumed that 17β-Estradiol has more effect on the development and differentiation of osteoclasts than those of osteoblasts and contributes to the initial bone formation most efficiently by inhibiting osteoclastic action and stimulating osteoblasts.

      • LPLI 최적분사제어맵 작성을 위한 실험 장치 개발

        장원석,이충훈 서울産業大學校 2005 논문집 Vol.54 No.2

        Liquefied propane injected from most commercialized LPLI system do not evaporize flashly but need some time to evaporize liquid film. LPLI system has a severe problem in vaporizing liquid fuel at cold start condition. To evaporize liquefied propane instantly the liquefied propane must be injected with condition of high temperature and pressure in the range of BLEVE (boiled liquid expanding vapor explosion). However in the range of BLEVE liquefied propane injection could cause weak shock wave. A Simulator which guarantees the exact control of temperature and pressure of injected liquefied propane was designed and made in this research. High pressurized vessel in which liquefied propane was contained and electric power control system controlled by personal computer was developed. Successful control of temperature and pressure of injected liquefied propane was identified in the simulator.

      • 제강슬래그 이용 오염하천수의 고속여과시스템 개발

        장원석,박대원 서울産業大學校 2005 논문집 Vol.54 No.4

        본 연구는 고부하 하천·호소에 대해 고효율·고속으로 처리할 수 있고 유량변동에 충분히 대처 가능한 콤팩트한 처리시스템에 관한 것이다. 연구결과로 기존정화법의 처리한계(BOD=20-30㎎/L)보다 10배 이상의 부하에서도 높은 처리효율(COD제거율 83%, SS제거율 :95%, 총인 제거율:98%, 색도 제거율:92%)을 보이며 빠르게(15분-30분) 처리하고, 콤팩트한 시스템(기본의 1/5공간소요)으로 처리비용을 줄일 수 있는 것으로 나타났다. 또한 폐기되는 제철슬래그를 특수가공한 수처리제로 처리를 행함으로 자원을 재활용하고 더 나아가 고부가가치 상품으로 활용할 수 있는 시스템이다.

      • KCI등재
      • KCI등재

        순/구개열 환자에서의 교정-보철 치험례

        장원석,최영철,이긍호 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.3

        순ㆍ구개열(cleft lip and palate)은 구강악안면 영역에서 가장 빈번하게 발생하는 선천성 기형 중 하나로 유전적, 환경적 요인에 의해 발생된다. 순ㆍ구개열 환자는 입술, 코 등의 기형을 보이며, 치과적 문제점으로 , 이환측 측절치는 결손되어 있거나 과잉치가 존재하고 형태적 이상을 보이는 경우가 많고, 맹출하지 못하지 못하거나 이소맹출을 하게된다. 이른 시기에 수행된 수술의 반흔조직(scar tissue)으로 인하여 상악골 설장의 장애가 발생되어 흔히 골격성 Ⅲ급 부정교합이 야기되기 쉬우며, 섭식장애와 발음장애를 보이기도 한다. 이러한 복잡한 문제로 인하여 여러분야의 전문가들로부터 다양한 관리가 필요하다. 순/구개열(cleft lip and alveolus only)은 악안면 영역에 제한적으로 영향을 미친다. 비이환측은 전방으로 회전되어 수평피개가 증가되고, 이환측은 내측으로 회전되어 견치부에서 end to end 관계, 혹은 반대교합을 보인다. 순/구개열 수술은 이와 같은 문제점 등을 개선시키기 위한 것이며, 상악골의 전후방적 성장에는 큰 영향을 미치지 않는것으로 보고되고 있다. 본 증례는 좌측에 순/구개열을 가진 5세 3개월의 여아로 생후 3개월 및 3세에 두 번의 구순열 봉합 수술을 받았으며, 상악 좌측 유측절치와 영구 측절치가 결손되어 있었고, 다발성 우식증 및 비구누공(oroantral fistula)이 존재하였으며, 골격성3급 부정교합을 보였다. 그러나 본 증례가 지니고 있는 골격성 Ⅲ급 부정교합은 구순열 수술후의 반흔조직에 의한 것은 아닌 것으로 판단되었으며, 환자의 기능과 심미성을 회복하기 위하여 혼합치열기 동안 고정성 교정치료를 시행한 후 보철치료를 시행하여 비구누공을 key and keyway attachment와 Konus crown을 이용한 가철성 obturator로 폐쇄하여 양호한 결과를 보였다. 주요어 : 순/구개열, 교정치료, Obturator Cleft lip and palate is one of the most common congenital defects in oho-maxillo-facial region Because most patients undergo surgical repair in early life. the sagittal jaw relationships used to be deteriorated gradually from palate surgery up to adulthood. Also. the maxillary lateral incisor may be absent or atypical-shaped in the cleft site and may not erupt or erupt ectopically, so multidisciplinary dental cares are needed for cleft lip and palate patients. The effects of the cleft lip and alveolus seem to be limited to that part of the dentofacial complex that surrounds the cleft area. In the maxillary arch, the anterior part of 7he non cleft segment has a tendency to be rotated forward. On the other hand, the cleft segment has a tendency to rotated slightly medially ;hence. the tendency for canines to be edge-to-edge and sometimes in crossbite. Lip and alveolus surgery adoquetely correct these problems, with little untoward effect on the skeletal maxillary-mandible relationships. In this report, the patient has a repaired lip and cleft alveolus on the left side with congenital missing on #62, #22, oronasal fistula. and skeletal class Ⅲ malocclusion which is not affected by lip surgery. Dental treatments for this patient including orthodontic(space supeivision, functional regulator in mixed dentition, fixed therapy in permanent dentition) and prosthodontic(removable obturator with key and keyway attachment and Konus crown) therapy were performed to improve the patient s functions and esthetics.

      • KCI등재

        세로토닌/도파민 길항성 항 정신병약물을 복용하는 정신분열병 환자에서 체중 증가와 세로토닌 2C 수용체 유전자 다형성의 관련성

        장원석,김신겸,유승형,조은영,윤세창,이동수,홍경수 대한정신약물학회 2005 대한정신약물학회지 Vol.16 No.2

        Objectives: Several lines of pharmacological evidences including the data of animal studies indicate that serotonin 2C receptor(5HT2C) is involved in the pharmacodynamic process of serotonin dopamine antagonists (SDA)-induced weight gain. Controversial data have been reported on the association between the polymorphisms of 5HT2C receptor gene and antipsychotics-induced weight gain. This study aims at investigating the association between the polymorphisms of 5HT2C receptor gene and SDA-induced weight gain in korean schizophrenic patients. Methods: Seventy-seven schizophrenia patients in their first episode or patients who did not take any antipsychotics for the previous two months were recruited. All the patients were administered with one of the SDAs(risperidone, olanzapine, quetiapine,clozapine) for 8weeks. Body mass index(BMI) were measured weekly during the 8weeks. The subjects were genotyped for the -759C/T and -697G/C polymorphism of the 5HT2C receptor gene. Results: The degree of linkage disequilibrium between the two polymorphic loci genotyped are almost 100%. Significant association was not observed between polymorphisms of the 5HT2C receptor gene(-759C/T and -697G/C) and SDA-induced weight gain after 8 weeks of treatment. Conclusions: Our data do not support the involvement of the polymorphisms of 5HT2C receptor gene(-759C/T and -697G/C) in SDA- induced weight gain. Further studies with sufficient sample size are warranted to follow up on the trend of high weight gain in the male patients having -759 T (-697 C) allele. Objectives: Several lines of pharmacological evidences including the data of animal studies indicate that serotonin 2C receptor(5HT2C) is involved in the pharmacodynamic process of serotonin dopamine antagonists (SDA)-induced weight gain. Controversial data have been reported on the association between the polymorphisms of 5HT2C receptor gene and antipsychotics-induced weight gain. This study aims at investigating the association between the polymorphisms of 5HT2C receptor gene and SDA-induced weight gain in korean schizophrenic patients. Methods: Seventy-seven schizophrenia patients in their first episode or patients who did not take any antipsychotics for the previous two months were recruited. All the patients were administered with one of the SDAs(risperidone, olanzapine, quetiapine,clozapine) for 8weeks. Body mass index(BMI) were measured weekly during the 8weeks. The subjects were genotyped for the -759C/T and -697G/C polymorphism of the 5HT2C receptor gene. Results: The degree of linkage disequilibrium between the two polymorphic loci genotyped are almost 100%. Significant association was not observed between polymorphisms of the 5HT2C receptor gene(-759C/T and -697G/C) and SDA-induced weight gain after 8 weeks of treatment. Conclusions: Our data do not support the involvement of the polymorphisms of 5HT2C receptor gene(-759C/T and -697G/C) in SDA- induced weight gain. Further studies with sufficient sample size are warranted to follow up on the trend of high weight gain in the male patients having -759 T (-697 C) allele.

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