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Impacts of Ambient Air Pollution on Health Risk in Korea: A Spatial Panel Model Assessment
임형선,조성훈,서병선 한국계량경제학회 2021 계량경제학보 Vol.32 No.1
This paper investigates the impact of air quality pollution on respiratory health risk in Korea. In particular, we consider transboundary effects of particulate matter (PM10) on the health risk of pneumonia by using the spatial panel model. PM10, generated by natural phenomena and anthropogenic activities, migrates to neighboring areas contributing to not only local but also ambient regional health risks. We employ the spatial panel model to explain the spillover effects of air pollution on the respiratory health risk. The panel data covers environmental, demographic and economic variables that are associated with pneumonia of 120 local districts in Korea during the period from 2010 to 2015. Empirical evidence based on non-spatial and spatial models commonly indicates that the impact of air pollution on pneumonia-related risk is significant. The spatial panel model assessment reveals improvement in explanation and evidences more significant effect of ambient air pollution on pneumonia related hospital visits. As such, evidences of spatial dependence and borderless impacts of air pollution on the health risk of pneumonia are found to be strong. We also investigate the spatial dynamics of the potential association between air pollution and respiratory diseases with respect to variations in wind direction by extending the conventional weight matrix specification. Empirical results imply that transboundary effects of PM10 on health risk are stronger for districts located downwind from Northwest districts than from other directions.
전신마취 중 발생한 우발적 표시풍선 분리의 효과적 해결- 증례 보고 -
임형선,손지선,최현호,김덕규,이정우,고성훈 대한중환자의학회 2010 Acute and Critical Care Vol.25 No.1
A 57-year-old female with lumbar spinal stenosis at L4-S1 was scheduled to undergo posterolateral interbody fusion. Intubation with a 7.0 size ID cuffed reinforced tracheal tube (Mallinckrodt(TM), Mallinckrodt Medical Atholen, Ireland) was uncomplicated, and any air leakage was not detected at that time. Two hours after the start of operation, an air leak was apparent at the trachea during ventilation in the prone position. Closer inspection of the inflation tube and pilot balloon showed that the pilot balloon had become detached. Because she was being operated on in the prone position, and ventilation was only possible at a less than optimal state, we attempted to fix this without having to reintubate the patient`s trachea. Our solution involved inserting a 21-gauge needle into the inflation tube and a handheld aneroid manometer was then connected to it. The tube cuff was thereafter inflated up to a pressure of 20 cmH2O. In conclusion, careful manipulation is recommended when performing intubation and a needle connector may help secure the airway if the pilot balloon becomes detached during the procedure.
Tracheal rupture after endotracheal intubation - A report of three cases -
임형선,Jung Hee Kim,Deokkyu Kim,Jeongwoo Lee,Ji-Seon Son,Dong-Chan Kim,고성훈 대한마취통증의학회 2012 Korean Journal of Anesthesiology Vol.62 No.3
Tracheal rupture is a rare but serious complication that occurs after endotracheal intubation. It usually presents as a linear lesion in the membranous wall of the trachea, and is more prevalent in women and patients older than 50years. The clinical manifestations of tracheal injury include subcutaneous emphysema and respiratory distress. We report the cases of three female patients of old age presenting tracheal rupture after endotracheal intubation. Two cases received surgical repair without complication and one recovered uneventfully after conservative management. We presume that the tracheal injuries were caused by over-inflation of cuff and sudden movement of the tube by positional change. Therefore, we recommend cuff pressure monitoring during general anesthesia and minimized movement of the head and neck at positional change. Tracheal rupture is a rare but serious complication that occurs after endotracheal intubation. It usually presents as a linear lesion in the membranous wall of the trachea, and is more prevalent in women and patients older than 50years. The clinical manifestations of tracheal injury include subcutaneous emphysema and respiratory distress. We report the cases of three female patients of old age presenting tracheal rupture after endotracheal intubation. Two cases received surgical repair without complication and one recovered uneventfully after conservative management. We presume that the tracheal injuries were caused by over-inflation of cuff and sudden movement of the tube by positional change. Therefore, we recommend cuff pressure monitoring during general anesthesia and minimized movement of the head and neck at positional change.
The change of stroke volume variation during thoracotomy or one lung ventilation
임형선,김동찬,김명종,유선우,기민종,강세린,김덕규 대한마취통증의학회 2019 Anesthesia and pain medicine Vol.14 No.3
Background: Stroke volume variation (SVV) is based on cyclic changes of intrathoracic pressure during respiratory cycle. Thoracotomy and one-lung ventilation (OLV) can lead to changes in airway and intrathoracic pressure. The aim of this study was to determine whether thoracotomy and converting from two lung ventilation to OLV could affect SVV values. Methods: Thirty patients who were scheduled for pulmonary lobectomy or pneumonectomy requiring OLV were enrolled. Induction and maintenance of anesthesia were performed with propofol and remifentanil via total intravenous anesthesia. Hemodynamic variables including mean arterial pressure (MAP), heart rate (HR), cardiac index (CI), and SVV were measured at intervals of 1 min for 10 min after thoracotomy and OLV, respectively. Results: MAP and HR increased from baseline at intervals between 3 and 10 min and between 4 and 10 min after thoracotomy, respectively (P < 0.001). CI increased between 4 and 10 min (P < 0.001). SVV did not change for 10 min after thoracotomy. After OLV, MAP decreased between 4 and 10 min (P = 0.112). SVV was the highest at 1 min after OLV. It returned to the baseline value at 7 min (P < 0.001). CI decreased between 8 and 10 min after OLV (P < 0.001). Conclusions: SVV can increase after OLV temporarily. Transient increase of SVV may be considered when fluid responsiveness is predicted by SVV during early period after OLV.
삼색도장버섯(Daedaleopsis tricolor TP3)에 의한 Methylene blue의 탈색과 분해
임형선,윤경하 순천향대학교 기초과학연구소 2000 순천향자연과학연구 논문집 Vol.6 No.1
Abstract In order to investigate the optimal conditions of decolorization and the degraded product of methylene blue by Daedaleopsis tricolor TP3 identified and isolatde from south korea, this study was performed. The effective medium for decolorization of methylene blue by the strain consisted Of 0.5% galactose, 0.12% yeast extract, 2.0% KH2PO4, 0.5% MgSO4 · 7H2O, 0.1% CaCl2ㆍ 2H2O, 0.002% thiamine-HCl, and 0.146% 2,2-dimethylsuccinate(DMS). The pH of the medium was adjusted to 5.5 with 1N NaOH solution. When the strain was grown in the above medium plus methylene blue at 30℃ for 7 days, a new product shown the maximum absorption at the region of 611nm wavelength and to be 0.67 of Rf with thin-layer chromatography was found. The new product was identified as azure C, tri-demethylated methylene blue derivative.