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폐암 환자의 기관지 세척 검체에 대한 고식적 세포도말검사, 세포 블록, 액상세포검사의 비교
임현이,임현이,주희재,김영배,홍순원 대한병리학회 2011 Journal of Pathology and Translational Medicine Vol.45 No.3
Background: The preparation of conventional smears (CS) from mucoid samples, despite mucolysis, can pose difficulties for cytotechnologists or cytopathologists. In recent years, liquid-based cytology (LBC) devices have been developed in attempts to improve the cytopreparation process. LBC improves both sample collection and sample preparation. Cell block preparations (CB) can be made from residual tissue fluids, and are a useful adjunct to smears. Methods: We retrospectively reviewed 3 preparations from 209 patients whose diagnosis was later confirmed via bronchoscopic biopsy, fine needle aspiration, gun biopsy or operation. Each case was categorized into one of three groups: “negative,” “atypical or suspicious” and “malignant.” Results: When conflating the “atypical” and “malignant” categories into a “positive” category, the sensitivity of each preparation was 74.4% in LBC, 72.9% in CS, and 76.5% in CB preparations. Specificity was 98.7%, 94.7% and 98.7%, respectively. By combining LBC and CB, the sensitivity is 78.2%. Conclusions: Among three different preparation methods, sensitivity is highest in the CB method. LBC has many advantages in evaluating cell morphology and by combining CB method, the sensitivity can be improved slightly. The application of all three methods may prove helpful when one or another method proves diagnostically inconclusive.
임현이,김정선,심철,Yim, Hyun-Ee,Kim, Jung-Sun,Shim, Chul 대한세포병리학회 1996 대한세포병리학회지 Vol.7 No.2
Intraoperative cytologic examination of intracranial tumors using crush preparation provides useful information in operative decision making. The diminutive nature of many biopsy specimens, particularly those obtained by stereotactic neurosurgical procedures emphasizes the importance of combining the cytologic smear method with conventional frozen section interpretation. The great advantage of the cytologic smear method resides in its suitability for the study of minute fragments of tissue, allowing retention of the majority of the specimen for optimal processing. We present the cytologic features of 3 cases of intracranial germ cell tumors(2 germinomas and 1 endodermal sinus tumor), using crush preparation during intraoperative diagnosis and compare them with histologic findings. The cytologic features of the germ cell tumors were similar to those of the respective gonadal counterparts. The cytologic differential diagnosis of both types of germ cell tumors is described.
태아폐를 닮은 폐 내배엽 종양 : 1예 보고 Report of a case
임현이,류한영,최호,임상현,소동문,이철주,심철,전미선 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1
We report a case of pulmonary endodeimal tumor resembling fetal lung in a 35 year-old woman, who complained of cough with sputum for 6 months. Pulmonary endodermal tumor is a very rare neoplasm of the lung and it is exclusively composed of complex branching tubules resembling the canalicular stage of fetal lung, lacking sarcomatous component of pulmonary blastoma. Prognosis of this tumor after adequate resection appears to be better than that for biphasic pulmonary blastoma.
세침흡인 세포학적 검사로 진단한 폐의 Nocardiosis - 1예 보고 -
임현이,박광화,Yim, Hyun-Ee,Park, Kwang-Hwa 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.2
Nocardia, aerobic members of the order of Actinomycetaceae, produces infections in human lung. Nocardial infection is associated with underlying diseases of immuno-suppression or treatment with corticosteroid. It is difficult to detect Nocardia by sputum examination or histologic sections and it has rarely been diagnosed by fine needle aspiration of the lung. We describe a case of pulmonary nocardiosis in a 72 year-old man, diagnosed by fine needle aspiration, which was confirmed by culture of aspirates. The aspirates showed neutrophil-predominant inflammatory cells with microorganisms demonstrated by Gomori methenamine silver and Gram stain. The organisms had characteristic long blanching filamentous structures. The lesions on chest X-ray were in resolution with antimicrobial therapy.
임현이,박영년,이광길,Yim, Hyun-Ee,Park, Young-Nyun,Lee, Kwang-Gil 대한세포병리학회 1992 대한세포병리학회지 Vol.3 No.2
Meningioma is the most common neoplasm of central nervous system which is hardly diagnosed by cytologic examination. However, preoperative cytologic diagnosis can be easily made in the case of extracranial meningioma, especially in head and neck lesion. We recently experienced a case of fine needle aspiration cytology of meningioma in sub-mandibular area of a 24 year-old male patient. The smear revealed high cellularity in the clean background. individual tumor cell of nests or syncytium had round or oval nuclei with fine chromatin and moderate amount of lightly stained cytoplasm with indistinct margin. Characteristic cellular whorls, intranuclear inclusions and scattered psammoma bodies made it easy to diagnose a meningioma.