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임창준 大韓顎顔面成形再建外科學會 1997 Maxillofacial Plastic Reconstructive Surgery Vol.19 No.3
Autogenous bone grafting has a broad range of applications and implications, and also limitations, though it is the oldest and most important reconstructive techniques in the oral and maxillofacial surgical field. Further understanding of bone healing mechanisms, bone physiology and bone biology, transplantation immunology, and development of tissue banking procedures had enabled oral and maxillofacial surgeons to reconstruct even the most difficult bony defects successfully with the preserved allogeneic bone implant. Now autogenous bone and allogeneic bone implants present a wide variety of surgical options to surgeons, whether used separately or in combination. The surgeons are able to make judicious and fruitful choices, only with a through knowledge of the above-mentioned biologic principles and skillful techniques. The author evaluated 116 cases where allogeneic bones were transplanted for oral and maxillofacial reconstruction.
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家兎 頭蓋下顎關節 關節圓板의 構造에 關한 微細血管照影術 및 電子顯微鏡的 硏究
任昌俊 圓光大學校 1990 論文集 Vol.24 No.2
顎關節 關節圓板은 下顎頭와 下顎窩 사이에 位置하여 關節腔을 上,下 두개의 腔으로 兩分시킨다. 關節圓板의 前方部에는 外側翼突筋이 一部 附着되며, 關節圓板의 後部에는 關節圓板後組織이 連結된다. 組織學的으로 顎關節의 關節圓板은 緻密한 纖維性 結合組織 惑은 纖維性 軟骨組織으로 構成되어 있으며 關節圓板의 두께는 矢狀面으로 보아 前方은 比較的 두꺼운 편이고 中間部는 가장 菲薄하며 後方은 가장 두꺼운데, 그 뒷쪽의 圓板後組織은 血管과 神經이 豊富한 疎性結合組織이다. 顎關節 關節圓板에 關한 實驗을 위해서는 實驗動物의 選定이 重要한데 이제싸지 家兎를 使用한 境遇가 가장 많았다. 그러나 家兎를 實驗動物로 選定하는데 對한 反對 意見도 많다. 이에 著者는 家兎의 頭蓋下顎關節部 骨構造에 關한 肉眼的 所見, 微細血管照影術을 利用한 關節圓板 周圍의 血管分布 所見, 光學顯微鏡 및 透過電子顯微鏡을 利用한 關節圓板細胞의 微細構造, 그리고 走査電子顯微鏡을 利用한 關節圓板 表面의 3次元的 微細構造를 觀察한 結果 다음과 같은 結論을 얻었다. 1) 家兎 顎關節의 前上方 側頭鱗骨 關節面과 後下方 下顎頭의 關節面은 咀嚼時 眞正한 意味의 機能的 關節面을 이룬다. 2) 固有 關節圓板組織 內에는 血管의 分布가 전혀 없다. 다만 關節圓板과 斜線上으로 重疊된 滑液組織에서는 血管의 走行을 볼 수 있었다. 3) 家兎 關節圓板을 構成하는 細胞는 主로 軟骨細胞로 이루어져 있다. 4) 關節圓板 內를 走行하는 膠原纖維의 다발은 꼬불꼬불하게 走行한다. 5) 關節圓板의 表面은 走査電子顯微鏡 所見에서 隆起와 陷沒部가 不規則한 波濤象을 보이고 있었으며, 여러 部位에서 噴火口 模樣의 構造를 볼 수 있었다. 6) 以上의 結果로 보아 家兎의 顎關節은 人間의 顎關節과 機能解剖學的으로 거의 비슷하며, 關節圓板組織은 壓力을 잘 吸수하며 견딜 수 있는 構造라고 生覺된다. Craniomandibular disc, which is located between the mandibular condyle head and mandibular fossa, separates the craniomandibular joint cavity into the upper and lower cavity. Some of the lateral pterygoid muscle fibers are anteriorly attached to the anterior band of the craniomandibular disc and the postrior band was connected to the retrodiscal tissue postriorly. Histopathologically, the temporomandibular joint disc is composed of dense fibrous connective tissue or / and of fibrous cartilaginous tissue. Sagittally the disc is composed of 3 portions, the anterior band, the intermediate zone, and the posterior band. The posterior band is the thickest portion and the intermediate zone is the thinnest portion. There are many animal models for experiment of the temporomandibular joint study. And the rabbit is the most frequebtly used experimental animal model of all animals. But there are not a few objections to this seletion of rabbits as the experimental model for CMJ study. So it is very important to know about the normal structure of the rabbit craniomandibular joint. Gross observation of the bone anatomy of the craniomandibular joint, microangiographic study of the vascularization of he craniomandibular joint disc and its peritissues with india ink, histologic study of the ultrastructure of the disc cells using LM and TEM, and observation of the disc surface using SEM were done in rabbits and the results were summerized as follows. 1. The bony anatomy of the rabbit was very similar to that of the human, except the posterolateral opening of the CMJ cavity. 2. There are no vascularization in the disc proper. But the posterior border of the rabbit CMJ disc seems to be vascularized rich in horizontal view, because of the superimposition of the retrodiscal tissue. 3. Rabbit CMJ disc cells were mainly composed of chondrocytes. 4. The bundles of collagen fibers of the rabbit CMJ disc run in the wavy winding pattern. 5. There are Many ridges, humps, and furrows on the rabbit CMJ disc surface. So they are thought to be able to distribute and absorb the external forces.
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가토 악골에 매식된 Apatite-Wollastonite Glass Ceramic의 생체반응에 관한 실험적 연구
任昌俊,金慶勖,申承澈,金豪建,申建澈 단국대학교 1992 論文集 Vol.26 No.-
The authors implanted the Apatite Wollastonite Glass Ceramic(AWGC) powders in the rabbit maxillae to evaluate the possibility of clinical use as an artificial bone substitute material. Firstly we made AWGC and analized powder X-ray diffraction pattern of glass after crystalization. Secondly we made animal experiment with New Zealand white rabbits. The rabbits were sacrificed at the day of opstoperative 2 weeks and 4 weeks after implantation. We took the radiography of the maxillae block specimens, each of which includes the AWGC, at the day of sacrifice. And the block specimens were routinely prepared for the SEM and EDX study. We observed the attitudes at the border between the bone and the material with the SEM, and we searched the components such as Ca or P by use of EDX and compared the periodic changing data. The obtained results are as follows : 1. On SEM findings, silica band-like zone was found between the bone and the implanted materials at 2-week specimen, and this zone was found diffusely mingled between the bone and the implanted meterials at the 4-week specimen. 2. On intraoral X-ray findings, the border line was definitely found between the bone and the the material just after implantation of AWGC, but the border line became difused and fusion was occasionally found at the border area. 3. There was a little change in the natural bone components at the border area, and Ca or P was drawn out from Awgc at the border area. 4. Si of AWGC was increased as the time being, and AWGC was dissolved with leakage of Ca and P. So it is suggested that the intermediate zone of Calcium Phosphate Apatite was formed at the border area by Ca and P from AWGC dissolution, and it makes AWGC further tightly bonded to the bone.
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