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방사선 조사와 병행 처리한 녹차 Polyphenol의 혈구암세포 사멸 촉진 효과
이홍수,Lee Hong Su 대한방사선사협회 2002 대한방사선사협회지 Vol.28 No.1
The Green tea, one of the most popular and favorite drinks in eastern societies, has been reported to have various therapeutic properties. These includes anti-cancer, anti-oxident, anti-endocrine disrupter effects. Its anti-cancer effect was said to be ac
이홍수 한국음악교육학회 1988 음악교육연구 Vol.7 No.-
In elementary school music education, the text book is one of the main materials for music learning. The text book is developed basing on the music currciulum. In 1955, a music curriculum was developed for the first time and have changed in 1963, 1973, 1981, and 1987. According to the curriculum, music text books were developed and have changed every time a few years late. The purpose of this study was to observe the contents of those text books in each period and to make suggestions appropriate for the development of music text books for the next periods. The following suggestions were addressed: 1) Since 1973, music educators have developed a relatively advanced music curriculum gradually emphasizing the ideas of the conceptual approach. However, the contents of music text books have been structured according to difficulty and in seasonal order of musical pieces. The contents of the books should be re-structured basing on the spiral and conceptual approach to music teaching and the concept of confrehensive music education by framing lesson units according to the concepts of musical elements and activities. 2) Korean-based repertoire should be provided with as the main materials for school use. Musical materials based on the traditional Korean music idioms provide students with oppertunities to cultivate appreciation for their cultural heritage and to become acquained with other cultures. 3) The contents of music text books should be structured with the aim of integrative musical activities including singing, playing, listening, moving, and creating to develop the concepts of musical elements. 4) The most rewarding experience in music learning is creating and performing students` own compositions. Exploring and observing of musical phenomena, deciding why it occurs and what its effects are, and creating their own music are very special experiences and serve as the greatest motivation for music learning. Therefore, the contents of music text books should be structured with the aim of providing a variety of creative musical activities. ECN
Cholesterol Oxidase를 생산하는 방선균분리주 HSL-613의 동정
이홍수,이인애,최용경,이희구,이근철,박용하,오태광,최인성,정태화 한국산업미생물학회 1994 한국미생물·생명공학회지 Vol.22 No.4
임상진단용 산화효소인 cholesterol oxidase를 생성하는 방선균 분리주 HSL-613을 토양으로부터 분리하여 ISP(International Streptomyces Project) 분리법과 화학적 방법으로 동정하였다. 분리주 HSL-613의 모양은 spiral 형태이며, 포자는 원형으로 smooth type이었다. 분리주 HSL-613의 세포벽 성분은 LL-DAP(diaminopimelic acid)로 나타났으며, chromosomal DAN의 평균 G+C 함량은 59%였고, 지방산은 주로 iso-branched와 anteiso-branched로 구성되었으며, menaquinone은 MK-9(H_6, H_8)을 가지고 있었다. 세포내의 당은 육탄당인 galactose, glucose, mannose, 그리고 오탄당인 robose로 구성되어 sugar pattern의 경우는 Streptomyces와는 전혀 다른 특징적 조성을 이루고 있었다. 5S rRNA의 염기서열을 sequencing한 결과 일반적으로 Actinomycetes의 경우 120개의 nucleotide를 가지고 있으며 본 분리주의 5S rRNA sequencing을 type strain인 Streptomyces griseus subsp. griseus KCTC 9080과 비교한 결과 120개의 nucleotide를구성하고 있으므로 형태학적, 생리학적, 화학적 특성을 조사하고 type strain과 비교하여 동정한 결과 분리주 HSL-613을 Streptomyces sp. HSL-613이라고 명명하였다. An actinomycete strain, HSL-613 was isolated from soil and identified by International Streptomyces Project (ISP) and chemotaxonomic methods. The spore chain of the strain HSL-613 appears in a spiral shape, and its spores are spherical shape with smooth surface. The cell wall contains LL-diaminopimelic acid (DAP). Menaquinone MK-9 (H_6, H_8) and iso- and anteiso-branched fatty acids were detected from whole cell extract. Sugars identified from whole cell extract include galactose, glucose, mannose and ribose, which are distinct from general sugar patterns of Streptomyces. Average G+C content in the chromosome is 59%. 5S rRNA of HSL-613 consists of 120 nucleotides as determined by comparing with that of a type strain Streptomyces griseus subsp. KCTC 9080. Through morphological, physiological, and chemical characterization, HSL-613 was identified and named as Streptomyces sp. HSL-613.