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동의보감(東醫寶鑑) 중(中) 길경(桔梗)이 주약(主藥)으로 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察)
이태형,이성준,허진,신동근,이재철,신용서,윤용갑,Lee, Tae-Hyung,Lee, Sung-Jun,Huh, Jin,Shin, Dong-Gean,Lee, Jae-Cheol,Shin, Yong-Seo,Yun, Young-Gab 대한한의학방제학회 2010 大韓韓醫學方劑學會誌 Vol.18 No.1
This report describes 90 prescriptions related to the use of Platycodi Radix main blended from Dongeuibogam. The following conclusions were reached through investigations on the prescriptions that use Platycodi Radix as a key component. Prescriptions that Platycodi Radix was taken as a monarch drug are utilized for 30 therapeutic purposes, for example, cough disease, throat disease, abscess and pus, and wind disease. In particular, 12.1% of prescriptions appear in the chapter of cough, and 9.9% of those appear in the chapter of throat, and each 8.8% of those appear in the chapter of abscess and of wind disease. Prescriptions that utilize Platycodi Radix as the main ingredient are used in the treatment of cough disease, throat disease and abscess, and they are also used for treating 74 different types of disease. The prescriptions are compounded with Platycodi Radix as a monarch drug are related to exogenous agents such as wind-cold pathogen, wind-heat pathogen, epidemic diseases, and endogenous agents such as seven emotions, and non-endo-exopathogenic factors like excessive labor, deficiency of Qi and blood, phlegm-mass, phlegm-fire, ect. The dosage of Platycodi Radix is 2pun(about 0.75g) to 1nyang(about 37.5g), however 1don (about 3.75g) has been taken the most for clinical application. We can find out that according to herbs or prescriptions blended with it self, Platycodi Radix makes a variety of functions to penetrate lung stagnancy and remove phlegm, relieve throat pain and get rid of pus, and regulate Qi flow. And Gamgiltang is the most useful base prescription which used the Platycodi Radix as the main component.
이태형,Lee, Tae-Hyeong 한국과학기술단체총연합회 1995 과학과 기술 Vol.28 No.1
신비롭고 아름다운 밤하늘의 별자리를 관측하는 동호인들의 모임으로 한국 아마추어 천문학회는 91년에 재창단되어 「별의 축제」등 우주관측행사를 벌이고 있다.
이태형,박춘수,Lee, Tae-Hyeong,Park, Chun-Su 한국시스템엔지니어링협회 2003 시스템엔지니어링워크숍 Vol.1 No.-
In this study, we have analyzed the cost of korea high-speed railway system. The predicted cost in planning phase and adjustment data to 5th year are collected. Then, predicted cost is compared with adjustment in year/item/system base. We make a project history table for criteria to review project history and research & development activity. We have developed CBS(cost breakdown structure) and allocated adjustment data to them. It is shown that cost prediction related to research & development activity in planning phase is relatively correct.
이태형,서승일,박춘수,유한성,김기환,Lee, Tae-Hyung,Seo, Sung-Il,Park, Choon-Soo,Yoo, Han-Sung,Kim, Ki-Hwan 한국시스템엔지니어링학회 2005 시스템엔지니어링학술지 Vol.1 No.1
Systems Engineering is the process that controls the technical system development effort with the goal of achieving an optimum balance of all system elements. FRACAS(Failure Reporting an d Corrective Action System) is one of RAMS(Reliability, Availability, Maintainability, Safety) tasks which is conducted from a manufacturing phase. FRACAS is to determine the basic cause of failure resulting from design or manufacture, and to provide a closed-loop method of implementing corrective action. This paper presents the FRACAS established for assessment of the reliability, the analysis and management of the failure data for Korean High Speed Train and application cases.
마하젠더 간섭계로 구성된 실리카 평판 광 도파회로 트라이플렉서의 설계 및 분석
이태형,이동현,정영철,Lee, Tae-Hyung,Lee, Dong-Hyun,Chung, Young-Chul 한국광학회 2007 한국광학회지 Vol.18 No.6
실리카 평판 광집적회로 마하젠더 간섭 구조를 이용한 트라이플렉서를 제안하고, 시뮬레이션을 통해 그 특성을 분석하였다. 1310 nm 대역과 $1480{\sim}1560nm$ 대역을 분리하기 위하여 마하젠더 암의 길이 차는 1310 nm 파장의 정수배 더하기 반 파장으로 하고, 방향성 결합기의 균형도는 $1480{\sim}1560nm$ 대역에서 적정화하였다. 이와 같은 마하젠더 간섭 구조를 한 단 더 사용함으로써, 매우 우수한 채널 누화 특성을 얻을 수 있었다. 1490 nm 대역과 1550 nm 대역을 추가적으로 분리하기 위하여 마하젠더 간섭구조를 추가로 두 단 더 사용하였다. 삼차원 BPM과 전송행렬방법을 통하여 각 채널들 사이의 낮은 누화 특성을 확인하였고, 제작 과정에서 발생할 수 있는 공정오차에 둔감한 특성을 보임을 확인하였다. A triplexer based on a silica planar lightwave circuit Mach-Zehnder nterferometer(MZI) is proposed and its characteristics are analyzed through simulations. To separate 1310 nm band and $1480{\sim}1560nm$ band properly, the path length difference of an MZI is set to be the multiple and half of the wavelength 1310 nm and the balance of the directional coupler is optimized in the $1480{\sim}1560nm$ band. The same MZI is additionally cascaded to provide good crosstalk characteristics. The 1490 nm band and 1550 nm band are further separated using additional two stage MZI's. A three-dimensional BPM and transfer matrix method analysis predicts the low crosstalk characteristics and the fabrication-error-tolerance of the proposed triplexer.
Paenibacillus sp. DG-22에서의 β-xylosidase 생합성 조절
이태형,임평옥,이용억,Lee, Tae-Hyeong,Lim, Pyung-Ok,Lee, Yong-Eok 한국생명과학회 2007 생명과학회지 Vol.17 No.3
효소생산을 최적화하기 위해서 Paenibacillus sp. DG-22에서의 ${\beta}-xylosidase$ 생합성 조절을 연구하였다. Paenibacillus sp. DG-22의 ${\beta}-xylosidase$는 배양액에 존재하는 탄소원에 의해 조절되는 것으로 관찰되었다. ${\beta}-Xylosidase$의 합성은 xylan과 methyl ${\beta}-D-xylopyranoside$ (${\beta}MeXyl$)에 의해 유도되었으나 쉽게 대사되는 단당류에 의해서는 약간 억제되었다. ${\beta}MeXyl$가 ${\beta}-xylosidase$의 유도를 위한 최적의 기질임을 확인하였고 가장 효과적인 유도는 10 mg/ml의 농도에서 얻어졌다. ${\beta}-Xylosidase$의 생산은 세포의 생장과 연관된 양상을 나타내었으며, 대수기 말에 최대양이 형성되었다. Glucose와 xylose가 존재하면 ${\beta}-xylosidase$의 활성 수준이 감소하는 것으로 보아 이 효소의 생합성은 catabolite repression을 받는것으로 보인다. SDS-PAGE와 활성염색 기술을 이용하여 ${\beta}Mexyl$가 이 효소의 생합성을 유도하며 약 80 kDa 크기의 하나의 ${\beta}-xylosidase$가 존재함을 알 수 있었다. Regulation of ${\beta}-xylosidase$ synthesis in Paenibacillus sp. DC-22 was studied to optimize the enzyme production. ${\beta}-Xylosidase$ synthesis of the Paenibacillus sp. DG-22 was observed to be regulated by carbon sources present in culture media. The synthesis of ${\beta}-xylosidase$ was induced by xylan and methyl ${\beta}-D-xylopyranoside$ (${\beta}MeXyl$) but slightly repressed by readily metabolizable monosaccharides. ${\beta}MeXyl$ was found to be the best substrate for the induction of ${\beta}$-xylosidase and the most effective induction was obtained at a concentration of 10 mg/ml. ${\beta}-Xylosidase$ production showed a cell growth associated profile with the maximum amount formed during the late exponential phase of growth. The presence of glucose and xylose decreased the level of ${\beta}-xylosidase$ activity indicating that its production was subjected to a form of carbon catabolite repression. SDS-PAGE and zymogram techniques demonstrated the induction by ${\beta}MeXyl$ and revealed the presence of one ${\beta}-xylosidase$ of approximately 80 kDa.
기술난이도와 기술성숙도를 이용한 핵심기술 연구개발 위험도 관리에 관한 연구
이태형,Lee, Taehyung 한국군사과학기술학회 2016 한국군사과학기술학회지 Vol.19 No.6
In the Core Technology R&D of the defence area, the development of the related core element technology could be the foundation to develop advanced weapon system in the future. But it might make various problems if you can not accurately define the TRL of the element technology. In other words, if the technology is not sufficiently mature and then the project starts, it might require an increase in the development period and additional cost. Finally the system will be in an incomplete state and result in user dissatisfaction and the project failure. Therefore it is a very important task to properly assess the TRL for a successful project. In this study, We propose the method for risk management of core technology R&D project of the defence area using the QFD process with degree of difficulty and technology readiness level. It is also presented the process to determine the risk level using TRL and Degree of difficulty. Finally We apply this method to UGV system for verifying the result of this study.