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이치훈,강봉균,이영돈 한국발생생물학회 2014 발생과 생식 Vol.18 No.1
This study was investigated spawning behavior, structure of egg masses and egg development in Aplysia kurodai inhabiting the coastal waters of Jeju Island, Korea. The mating and courtship behavior of A. kurodai occurred in the form of unilateral copulating with chain formation. In chain copulation, only the first animal acted as a female; the second and succeeding animals acted as males (sperm donors) to the animals in front and as females to the animals behind. The fertilized eggs were packaged in capsules that are embedded in jelly to form a cylindrical string called an egg masses. The number of capsule per cm of the egg masses was 55 to 60 capsules and each capsule within the egg masses held 15 to 25 eggs. After spawning, the egg masses were bright yellow or orange in color. This egg masses color not changed until embryos developed into trochophore stage. Thereafter, as embryo developed from trochophore stage to veliger stage the egg masses color became brownish. The fertilized eggs were spherical, with a diameter of approximately 80±1 μm at spawning. At 5 to 6 days after spawning, the embryo developed into trochophore stage and began to rotate within the egg capsule. In the trochophore stage, the precursor of the velum, called the prototroch or prevelum, developed. At 10 days after spawning, the prevelum is transformed into the velum, and the trochophore developed into veliger stage. Between 10 to 15 days after spawning, the veligers broke out of the egg capsule, and hatched as free-swimming larvae
Gonadal Development and Reproductive Cycle of Sea Hare Aplysia kurodai in Jeju Coastal Waters
이치훈,강봉균,이영돈 한국발생생물학회 2011 발생과 생식 Vol.15 No.3
Gonadal development and reproductive cycle of Aplysia kurodai inhabiting the coastal waters of Jeju Island,Korea were investigated based on monthly changes of gonadosomatic index, gametogenesis, and developmental phases of ovotestis. A. kurodai was simultaneous hermaphrodite; the ovotestis generally embedded in the posterior dorsal surface of the brownish digestive gland. The ovotestis is composed of a large number of follicles, and both oocytes and sperm are produced in the same follicles. In the sampling periods, the adult A. kurodai population have characteristic of seasonal pattern present during only 10 months. The reproductive cycle can be grouped into the following successive stages in the ovary: inactive (December to February), active (December to April), mature and spawning (April to September). The gonadal development of A. kurodai coincided with rising temperature, and spawning occurred from April to September,when the temperature was high. The histological observations of the ovotestis suggested that this species have a single spawning season that extend over six months
The Role of Real-time PCR for Rapid Diagnosis of Pleural Tuberculosis
이치훈,김이형,최천웅,유지홍,박지영,박명재,강홍모,이종후 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-
Background: To evaluate the role of real-time polymerase chain reaction (PCR) in pleural fluid (PE) specimens as non-in-vasive method for pleural tuberculosis (TB). Methods: We analyzed medical records of patients who underwent thoracentesis to evaluate unilateral PE from Jan, 2009 to Dec, 2010. The patients with TB empyema and positive smear for acid fast bacilli (AFB) in sputum were excluded. Results: In a total of 210 patients who underwent thoracentesis, a PE specimen was submitted for real-time TB-PCR. Overall, 56 (26.7%) patients had pleural TB and 154 had PE secondary to other diseases. TB was confirmed using positive culture for acid-fast bacilli (AFB) (n=7) or favorable clinical response to anti-TB medication (n=49). Of all patients, only two patients had positive real-time TB-PCR. They had negative AFB smear and culture of PE and were finally diagnosed as pleural TB. Therefore, sensitivity, specificity, positive (PPV) and negative predictive values (NPV) of real-time-TB-PCR testing in PE were 3.57%, 100%, 100% and 72.04%, respectively. In addition, three patients have positive AFB smear in PE and were finally confirmed to have pleural TB. Therefore, sensitivity, specificity, PPV and NPV of PE AFB smear were 5.36%, 100%, 100% and 74.4%, which were not different from those of real-time TB-PCR. Conclusions: The sensitivity of real-time TB-PCR of PE was low. However, real-time TB-PCR could be an additional non-invasive assay for fast confirmation of pleural TB, especially when it is added to AFB smear.
이치훈 한국경제연구원 2015 한국경제연구원 세미나자료 Vol.15 No.17
□ 금년 들어 중국 경제 및 금융 불안, 글로벌 리스크의 핵심으로 부상 ○ 중국 금융시장 위축에 따른 글로벌 동조화 현상이 뚜렷한 가운데, "중국의 경제위기"와 "중국發 경제위기"에 대한 우려가 동시에 제기 □ 이는 중국경제의 규모 확대뿐만 아니라, 질적 향상으로 글로벌 벨류체인이 변화하고 있는데에도 그 원인이 있는 것으로 평가 ○ 단순 임가공 무역국에서 부품 수출국으로의 전환 등 경제구조 변화로 과거 "세계의 공장"에서 "첨단제품제조"와 "시장"의 역할이 추가 □ 단기내 중국경제의 경착륙 가능성은 제한적 ○ 내년 중 철도·일대일로 등 인프라 투자와 이를 지원하기 위한 정부의 재정지출이 확대되는 가운데 선별적 통화정책 완화도 강화 ○ 서비스업·첨단산업 등의 성장도 기존 전통산업의 부진을 일부 상쇄 □ 다만, 2016년 중국경제 주요 리스크 요인의 확산 여부에 따라 성장률이 당국의 목표치 6.5%를 하회할 가능성도 상존 *3대 리스크 요인으로 부동산시장 더블딥·기업도산·금융불안이 우려 ○ 중국發 불안이 상시화되는 가운데, 이 경우 우리경제는 실물·금융·심리 등 다양한 파급 경로를 통한 전방위적 영향이 불가피 □ 가변적 차이나리스크에 실물 및 금융 분야 모두 적극 대응할 필요 ○ 신성장 동력 및 융합 기술 육성 등 비교 우위 확보 노력과 함께 마스터플랜 수립 등을 통한 중국시장의 제 2 내수시장화 정책도 강화 ○ 금융부문은 안정성 제고와 동시에 위안화 채권 발행 등 중국의 금융개혁이 수반할 수 있는 기회요인을 적극 활용