Newly Designed Hole-Injection Layer using Polymeric Nanospheres/PEDOT:PSS Continuous phase Films for Highly Air Stable OLEDs

이창연,이재호,강동진,고태욱,김태수,유승협,김범준 한국고분자학회 2013 한국고분자학회 학술대회 연구논문 초록집 Vol.2013 No.4

수직 안진을 동반한 뇌간뇌염 1례

이창연,장무환 동국대학교 경주대학 1993 東國論集 Vol.12 No.-

It is known that meningoencephalitis is the disease usually characterized by a hstory of headache, high fever and disturbance of consciousness. Its cause is usually virus. In most cases, inflammatory reaction involve the brain diffusely, but occasionally involve brain locally. In those cases in whom inflammatory reaction involved brain locally, specific symptoms appear according to the location involved. Clinically, we can suspect the site of brain where inflammatory reaction involved, according to clinical symptoms. We experienced a case of meningoencephalitis with downbeat nystagmus implying that the inflammatory lesion involve pontomedullary junction. It was confirmed by MRI. So, we report it with review of literatures.

High Performance All-Polymer Solar Cells via Side Chain Engineering of Polymer Acceptor

이창연,강현범,이원호,김태수,김기현,우한영,Cheng Wang,김범준 한국고분자학회 2015 한국고분자학회 학술대회 연구논문 초록집 Vol.2015 No.4

페경기 여성에서 호르몬 대체요법의 지질대사 및 골밀도에 대한 효과: 지속적 요법과 순차적 요법의 비교

이창연,이숙향,Lee, Chang Yun,Lee, Sukhyang 한국임상약학회 2000 한국임상약학회지 Vol.10 No.3

Menopausal women experience urogenitory and vasomotor symptoms with increased risk of osteoporosis and cardiovascular diseases, which can be reduced by hormone replacement therapy. However unopposed estrogen therapy has been associated with an increased risk of endometrial hypeiplasia or cancer. The objectives of this study were to compare effects of continuous vs. sequential hormone replacement therapy (HRT) on lipid profile, bone mineral density and menopausal symptoms of postmenopausal women and to assess how they perceive the menopause and HRT culturally. In this retrospective study, women in menopause longer than 6 months, normal in the mam-mogram and Papanicolaou smear, cholesterol level lower than 190 mg/dL or triglyceride level lower 4han 500 mg/dL were treated with Srogen (conjugated equine estrogen 0.625 mg tablet) and Provera (medroxyprogesterone acetate 2.5 mg tablet) for continuous treatment(CT) or Cycloprogynova (Estradiol valerate 2 mg and Norgestrel 0.5 mg complex tablet) for sequential treatment(ST). They were evaluated for lipid profile, bone mineral density, menopausal symptoms, side effects and their perception of menopause and HRT. As results, total sixty-seven patients out of ninety-four enrollees were included in final analysis (33 in continuous therapy, 34 in sequential therapy). There were significant decrease in total cholesterol ($15.04\pm3.17$, p=0.0001), LDL ($19.72\pm3.27$, p=0.0001), and increase in HDL ($5.89\pm1.63$, p=0.0001). Bone minora) density increased significantly with HRT ($0.02\pm0.11$, p=0.0001). But, there were no significant differences in change of lipid profile between continuous and sequential therapy: Total cholesterol, $13.12\pm4.7\;vs.\;16.91\pm4.3;\;LDL\;20.53\pm4.1\;vs.\;18.93\pm5.12:HDL\;7.15\pm2.3\;vs.\;4.67\pm2.2,\;p>0.05$. Incidences of flush reduced from $75\%\;(CT)\;to\;3.13\%\;and\;71.88\%\;(ST)\;to\;9.35\%$. The change of endometrium and breast were found 3 (CT) and 5 (ST) women, respectively. Most of women recognized that HRT is necessary $(70\%)$ for postmenopausal period but did not understand well the cardiovascular protective effect. In conclusion, hormone replacement therapy was effective in improving lipid profile, bone mineral density and menopausal symptoms in both continuous and sequential treatments with similar efficacy.

중소기업의 산・연 기술협력 성과 영향 요인

이창연,김병근 한국기술혁신학회 2019 기술혁신학회지 Vol.22 No.3

This study aims at examining the relationship among entrepreneurial orientation, absorption capability, alliance capability and cooperation performance in technological cooperation between SMEs and government-funded R&D Institutes. For empirical analysis, the study conducted a survey on total 2,895 SMEs participating in the technological cooperation programs operated by government-funded R&D Institutes, and collected 332 survey responses. Data were analysed using a structural equation model. Empirical results show that entrepreneurial orientation, absorption capability, and alliance capability influenced the performance of technological cooperation. In addition, alliance capability has a significant effect on absorptive capacity. In order for the technology cooperation between SMEs and government-funded research institutes being successful, efforts are needed to secure companies’ entrepreneurial orientation, absorption capability and alliance capability that has the capabilities that SMEs needs for technological cooperation. 본 연구는 중소기업과 출연(연) 간 기술협력과 성과 영향요인을 중소기업 관점에서 전략적 지향성 (기업가지향성), 역량(협력역량, 흡수역량)을 중심으로 분석한다. 기업가지향성의 기술협력성과에 대한 직접효과 및 간접효과, 협력역량과 흡수역량의 매개효과, 협력역량과 흡수역량과의 관계를 규명한다. 실증분석을 위해 출연(연)에서 운영하고 있는 기술협력 프로그램에 참여 중인 2,895개 중소기업을 대 상으로 설문조사를 시행하였으며 332개의 응답 자료를 수집하였다. 구조방정식 모형을 활용하여 분석 한 결과, 기업가지향성, 협력역량, 흡수역량 모두 기술협력을 통한 기술혁신성과에 긍정적으로 영향을 주는 것으로 나타났다. 또한 기업의 협력역량은 흡수역량에 통계적으로 유의한 영향을 주는 것으로 나 타났다. 중소기업과 출연(연)의 기술협력이 성공하기 위해서는 내부자원의 한계를 극복하기 위한 조직 차원의 기업가지향성과 협력과정을 관리하기 위한 역량, 협력을 통해 생산된 지식을 획득 및 활용하여 성과를 창출할 수 있는 역량을 확보하기 위한 노력이 필요할 것으로 보인다.

스테로이드 저항성 신증후군 환아에서의 Methylprednisolone 충격 요법의 치료 효과

이창연,하일수,정해일,최용,Lee Chang-Youn,Ha Il-Soo,Cheong Hae-Il,Choi Yong 대한소아신장학회 1997 Childhood kidney diseases Vol.1 No.2

목적 : 소아의 스테로이드 저항성 신증후군은 예후가 불량함에도 불구하고 지금까지 효과적인 치료방법이 없는 병이었으나 1990년 Mendoza등이 Methylprednisolone 충격 요법이 스테로이드 저항성 신증후군에서 효과적이라는 것을 보고하였다. 하지만 2년 뒤 Waldo 등은 Methylprednisolone 충격 요법이 Mendoza 등의 보고와는 다르게 스테로이드 저항성 신증후군에 효과가 적었다고 보고하여 이에 저자는 한국 소아에서 스테로이드 저항성 신증후군이 발생한 경우 Methylprednisolone 충격 요법의 효과를 알아보고 위의 보고의 서로 다른 결과를 확인하고자 본 연구를 시행하였다. 방법 : 1990년부터 1995년까지 만 5년간 서울대병원 소아과에 스테로이드 저항성 신증후군으로 입원한 소아를 대상으로 Methylprednisolone 충격 요법을 시행하여 $30{\pm}11$개월동안 추적 관찰하였다. 결과 : 1) Methylprednisolone 충격 요법 치료로 신증후군이 완해가 유도된 환아는 20명중 9명으로 45%이었다. 2) Methylprednisolone 충격 요법 치료후 신증후군의 완해가 유지된 환아는 20명중 9명으로 45%이었다. 3) Methylprednisolone 충격 요법에 반응이 없었던 환아중 만성 신부전으로 이행된 경우는 5례로서 25%이었다. 결론 : Methylprednisolone 충격 요법은 스테로이드 저항성 신증후군 소아의 45%에서 신증후군의 완해를 유도하고 유지시키는 효과적인 치료 방법이었다. Purpose : The Childhood Steroid Resistant Nephrotic Syndrome (SRNS) has a poor prognosis and there has been no effective therapy against SRNS of children. In 1990, Mendoza have reported that methylprednisolone pulse therapy was effective against SRNS of children. But in 1992, Waldo have reported that methylprednisolone pulse therapy was not as effective as in the report of Mendoza. So, retrospectively, we have studied 20 korean children with SRNS to evaluate the effect of methylprednisolone pulse therapy, Methods : Mothylprednisolone pulse therapy were given to 20 korean children with SRNS who admitted to Seoul National University Hospital from 1990 to 1995 and follow up was done Results : 1) During methylprednisolone pulse therapy, remission of nephrotic syndrome was induced in 45% of patients. 2) during follow up after the end of methylprednisolone pulse therapy, remission of nephrotic syndrome was maintained in 45% of patients. 3) 25% of patients has progressed to chronic renal failure. Conclusion : We think that the methylprednisolone pulse therapy is a effective therapy against SRNS of children with the 45%, remission rate of of SRNS in Korean Children

Study on Phase-Separated Domain Spacings of Active Layer and Photovoltaic Performances Correlation in All-Polymer Solar Cells

이창연,Li Yuxiang,Cheng Wang,우한영,김범준 한국고분자학회 2016 한국고분자학회 학술대회 연구논문 초록집 Vol.41 No.1

급경사 계곡류의 에너지와 배수압소산을 위한 Gabion 낙차공

이창연,배상수,지홍기 한국방재학회 2003 한국방재학회지 Vol.3 No.4

출연(연)의 중소기업 지원 강화를 위한 파트너기업제도 효율화 방안 연구

이창연,박문수,김필성,심현보 한국기술혁신학회 2014 한국기술혁신학회 학술대회 발표논문집 Vol.2014 No.10

소아 비만의 위험 인자와 비만한 자녀를 가진 가족의 특성에 관한 조사 연구

이창연,김웅흠 대한비만학회 1994 The Korean journal of obesity Vol.3 No.1

To study the risk factors of childhood obesity and the characteristics of the parents with obese child, We surveyed 676 primary-school children of 4-5-6th grade living in the isolated residential area for only the one large company employee and their farnilies, located in the suburb, at March 1990. The results were as follows; 1) The prevalence rate of childhood obesity is 19.2%. 2) The obesity index is significantly increased with the increase of birth weight(p$lt;0.05). But the percentage of obese children is not significantly different according to the duration of breast milk feeding(p$gt;0.05). 3) The percentage of obese children in the group who walk to school, or who exercise regularly, is not lower than in the group who do not.(p$gt;0.05) 4) The parental body mass index of the obese children are higher than those of the non-obese children(p$lt;0.05). 5) There is no significant difference of the percentage of obese children, according to the number of siblings, or to the order of birth(p$gt;0.05). 6) Both systolic blood pressure and diastolic blood pressure in the obese children are higher than those in tbe non-obese children(p$lt;0.05). 7) The recognition rate of childhood obesity by the parents with obese child is 74.1%, and most parents with obese child do not know the true medical Problems of childhood obesity exactly.