콜라겐 젤과 성장인자 전처치 및 피복재료가 다공성안와삽입물의 섬유혈관증식에 미치는 효과

이준영,김석영,유창국,이무석,이상렬,오중협,김성주.Joon-Young Lee. M.D.. Suk-Young Kim. Ph.D.. Chang-Kook You. Moo-Seok Lee. Sang-Yeul Lee. M.D.. Ph.D.. Jung-Hyub Oh M.D.. Ph.D.. Sung-Joo Kim M.D.. Ph.D. 대한안과학회 2005 대한안과학회지 Vol.46 No.6

Purpose: To determine the effect of bFGF complexed collagen gel, which allows constant release of bFGF along with biodegradation of the collagen gel. The specific study purpose was to determine whether it can accelerate the fibrovascular ingrowth into wrapped HA-coated porous alumina and to verify the safety of new wrapping materials. Synthetic polyester-urethane (Neuropatch?) and lyophilized bovine pericardium (Lyoplant?) were compared to donor sclera for the fibrovascular ingrowth into HA-coated porous alumina. Methods: The experimental and control groups, each consisting of 9 rabbits were wrapped with each wrapping materials (3 rabbits per wrapping material). The experimental group underwent pretreatment of bFGF-collagen gel while the control group did not. The fibrovascular ingrowth was compared at 2 and 4 weeks after implantation. Western blot analysis was conducted at 4 weeks using antibodies against CD141 and laminin. The rate of fibrovascular ingrowth was fastest in orbital implant wrapped with Lyoplant?. Results: Histopathologic examinations at 2 weeks showed no differences in distance and percentage area of fibrovascular ingrowth. Histopathologic examinations at 4 weeks showed that pretreatment of bFGF-collagen gel increased the fibrovascular ingrowth in the experimental group. Western blot analysis on experimental group also showed that the expressions of CD141 and laminin were increased by bFGF-collagen gel, thereby indicating that the fibrovascular proliferations were accelerated by bFGF released from the complex. Conclusions: bFGF-collagen gel increased the rate and degree of fibrovascular growth into hydroxyapatite- coated porous alumina by releasing bFGF as the collagen gel biodegraded. Both Lyoplant? and Neuropatch? were evaluated as safe for substitution of the donor sclera.

운동 선수에게 발생한 급성 비골건 아탈구의 수술적 치료: 증례 보고-2예

이준영,이자용,Lee, Jun-Young,Lee, Ja-Yong 대한족부족관절학회 2005 대한족부족관절학회지 Vol.9 No.1

Acute subluxation of the peroneal tendon is an uncommon injury which is predominantly associated with a trauma. Traumatic peroneal tendon subluxation in athletes is an uncommon cause of ankle pain. As a result, the diagnosis is often delayed. Numerous surgical techniques have been described for chronic peroneal subluxation or dislocation, however reports in acute cases are rare. Authors experienced two cases of acute subluxation of peroneal tendon in athletes which were treated by simple primary repair of superior peroneal retinaculum with good results.

후천성 심질환의 인공판막치환술에 대한 임상적 고찰

이준영,지행옥,Lee, Jun-Yeong,Ji, Haeng-Ok 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.6

Between September, 1972 and September, 1989, total 359 patients were operated for acquired heart disease at Department of Thoracic and Cardiovascular Surgery, Hanyang University Hospital. A consecutive series of 293 prosthetic valve replacement was also performed during this period. The results were summarized as follows; 1. There were 141 men and 218 women, whose ages ranged from 6 to 64 years, [mean 35.5 years] 2. Out of 293 cases, mitral valve replacement was 182 cases, aortic valve replacement was 39 cases and double valve replacement was70 cases. 3. Early post-operative death was 30 cases [Mortality; 8.4 %] and late death was 9 cases in the survivors. 4. Re-operation was 30 cases and operative mortality was 10%. 5. Mean post-operative interval was 76 months. [Ranged from 216 months to 2 months] 6. Among re-operation cases, primary prosthetic valve failure was 16 cases and paravalvular leakage was 2 cases. 7. Since January 1988, 79 cases of prosthetic valve replacement were performed and then 1 case was expired. [Mortality; 1.2 %]

족관절 유합술

이준영,박상하,Lee, Jun Young,Park, Sang-Ha 대한족부족관절학회 2014 대한족부족관절학회지 Vol.18 No.4

Ankle arthrodesis has been used as standard treatment of ankle arthritis unresponsive to conservative treatment. Transfibular approach was used for ankles with severe deformities and minimally invasive arthroscopic ankle arthrodesis was used for patients with mild deformities. Anterior approach may be used when lateral approach couldn't be performed. Tibiotalocalcaneal arthrodesis is standard treatment for coexisting ankle and subtalar arthritis, and modified Blair arthrodesis can be used if the talus body resection is necessary in severe talar necrosis. In serious infection of ankle arthritis, arthrodesis can be performed as staged operation. In cases with low bone density and severe deformities, Charcot arthropathy should be considered.

우리나라 인삼약초산업의 정책 추진현황과 성과

이준영,Lee, Jun-Yeong 한국인삼전략화협의회 2006 인삼·약초 Vol.4 No.1

중등도 및 중증의 무지 외반증 환자 치료에 변형된 중족골 원위부 갈매기형 절골술과 근위부 갈매기형 절골술에 대한 비교

이준영,박상수,Lee, Jun-Young,Park, Sang-Soo 대한족부족관절학회 2012 대한족부족관절학회지 Vol.16 No.1

Purpose: The purpose of our study is the comparison of radiological and clinical outcomes between modified distal chevron osteotomy and proximal metatarsal osteotomy for the patients who had moderate to severe hallux valgus deformity. Materials and Methods: In this retrospective study, we included 54 patients (65 feets) who underwent the operation of moderate to severe hallux valgus in our hospital from May 2007 to August 2010. Our study compares two groups. For Group 1, a modified distal chevron osteotmy and a distal soft tissue procedure were done and for Group 2, a proximal metatarsal osteotmy and a distal soft tissue procedure were done. The group 1 were 29 feets; the group 2 were 36 feets, and the average follow up was 9 months. Results: The radiological results show that the hallux valgus angle and the first-second intermetatarsal angle were significantly decreased in two groups. In each parameter, the correction of the hallux valgus angle was $19.1^{\circ}$ (Group 1) and $24.3^{\circ}$ (Group 2), the correction of the first-second intermetatarsal angle was $9.6^{\circ}$ (Group 1) and $10.3^{\circ}$ (Group 2). Shortening of the first metatarsal length was 0.87 mm (Group 1) and 0.77 mm (Group 2). There are no significant clinical results (American Orthopaedic Foot and Ankle Society score, AOFAS score) in two groups. Conclusion: It is thought that a modified distal chevron osteotomy and a distal soft tissue procedure are a considerable operative treatment of moderate to severe hallux valgus deformity because of the similar cilinical results, more simple operative techniques, and less complications than a proximal metatarsal osteotomy.

저전력 네트워크 기반의 확장 용이한 스마트 홈 IoT 시스템

이준영,유성은,Lee, Jun-young,Yoo, Seong-eun 대한임베디드공학회 2018 대한임베디드공학회논문지 Vol.13 No.3

There are increasing interests on smart home systems. However, most of the existing works focus on the functionality itself. In this paper, we propose an extensible smart home system based on low power networking such as CoAP, 6LoWPAN, and Zigbee. The proposed home IoT system consists of Home APP, Home Server, Home Broker, and Power Devices. Each component of the system is connected by the low-power network technologies aforementioned. As the end device, Power Device senses the current consumption of the attached appliance and controls the power to it. Power Device reports the sensing data to Home Server via Home Broker. The Home Broker enhances the scalability of the system. Home Broker extends the service area and the user's services, and it manages the connection of the underlying devices and processes, and transmits data to Home Server from Power Devices. Through the experimental evaluation, we show that the proposed system achieves the design goals such as extensibility and low power networking.

경거골유합술 후 발생하는 불유합과 관련된 인자에 대한 분석

이준영,김보선,이정우,Lee, Jun Young,Kim, Bo Sun,Lee, Jung Woo 대한족부족관절학회 2017 대한족부족관절학회지 Vol.21 No.3

Purpose: The aim of this study was to analyze the factors related to nonunion in tibiotalar arthrodesis. Materials and Methods: Eighty cases of ankle arthritis treated with tibiotalar arthrodesis in our hospital from November 2008 to November 2015 with more than one year follow up were analyzed. Simple anteroposterior and lateral radiographs after 6 and 12 months of surgery were analyzed. Union was defined as more than 50% connection of the trabecular bone at the ankle joint surface in the anteroposterior and lateral radiographs. The nonunion group was defined as no signs of union with persistent pain 9 months after surgery. The surgical approach, type of used screw, preoperative and postoperative ankle alignment, body mass index (BMI), bone mineral density, and patients' prior history were compared between the two groups. Results: There were 69 union cases and 11 nonunion cases. In the patient factors, the gender and BMI was related to nonunion (p<0.05). The mean preoperative and postoperative ankle alignment in the nonunion group was $9.93^{\circ}{\pm}6.92^{\circ}$ and $5.43^{\circ}{\pm}3.35^{\circ}$ respectively, and $9.80^{\circ}{\pm}7.55^{\circ}$ and $5.63^{\circ}{\pm}3.45^{\circ}$ in the union group, respectively; the difference was not statistically significant (p>0.05). In the technical factors, the transfibular approach showed a better relationship but the association was not significant (p<0.05). In 40 cases of the transfibular approach, 12 cases used cancellous screws, and 4 cases showed nonunion due to screw breakage. Conclusion: Technical factors, such as the surgical approach and the type of screw used can be a risk factor in nonunion. In addition, patients' factors, such as gender and BMI, must be considered to reduce the nonunion rate.

내측 반월상 연골판 후각 기시부 파열의 특징 및 관절경 소견

이준영,김동휘,하상호,이상홍,강정훈,Lee, Jun-Young,Kim, Dong-Hui,Ha, Sang-Ho,Lee, Sang-Hong,Gang, Joung-Hun 대한정형외과스포츠의학회 2009 대한정형외과스포츠의학회지 Vol.8 No.1

목적: 중년 이후에서 흔히 일어나는 내측 반월상 연골판 후각 부착 부에 발생하는 방사상 파열의 임상적 특성과 관절경적 소견을 문헌 고찰과 함께 보고하고자 한다. 대상 및 방법: 2005년 1월부터 2007년 4월까지 본원 정형외과에 내원하여 슬관절 내시경 수술을 시행 받은 환자 중 관절경상 내측 반월상 연골판 후각 부착 부 파열이 관찰되었던 환자 40명, 40례에 대해 의무 기록을 통한 후향적인 검사를 시행하였다. 남자 7명, 여자 33명이고, 평균 연령61(47~80)세이며, 외상 병력의 유무, 동반된 관절염의 등급 및 통증 발생 후부터 수술까지의 기간(유병기간), 자기공명영상 소견, 임상 증상 및 파열단의 모양과 치료법 등을 검토하였다. 결과: 외상 병력이 있었던 경우가 6례며, 34례는 외상 병력이 없었다. 단순 방사선 사진상 Kellgren-Lawrence 분류는 0-II형이 31례, III형은 9례 였으며, 관절경상 대퇴골 내과의 관절 연골 상태는 Outerbridge grade IV 형이 17례, III 형이 4례, II 형이 9례, I 형이 9례이었다. 유병기간은 평균 5.3개월이었으며, MRI 소견으로는 전례에서 축상면 또는 관상면에서 틈(cleft)나 시상면에서 유령 징후(ghost sign) 중 1개 이상이 관찰되었다. 파열단의 모양은 18례가 뭉툭한 형태, 12례가 수평 파열, 10례가 퇴행성 파열이었으며 수술법으로는 연골판 아전 절제술을 16례, 부분 절제술을 10례, 봉합술을 14례에서 시행하였다. 결론: 중년 이후의 연령에서 반월상 연골판 후각 부착부 파열은 외상 병력이 드물게 발생하며 심한 기계적 증상을 호소하며, 관절염을 동반하는 경우가 많다. 치료로 절제술 뿐만 아니라 봉합술을 시도해 볼만한 파열이 있었으며, 추후 그 치료 결과에 대한 연구가 필요하다. Purpose: We wanted to report the clinical characteristics and arthroscopic findings of radial tear in medial meniscus posterior horn insertion, commonly occurs in patient over middle age with documentary review. Materials and Methods: Retrograde study using hospital records was done to 40 cases in 40 patients who visited our hospital and had been performed knee arthroscopic surgery due to medial meniscus posterior horn insertion tear between January, 2005 to April, 2007. Seven cases were male and 33 cases were female with the mean age of 61 (range, 47-80). Trauma history, stage of arthritis, period between pain and operation, MRI findings, clinical symptoms and operation methods were evaluated. Results : Six cases had trauma history while 34 cases didn't. In simple x-ray, using Kellgren-Lawrence classification, 31 cases were between stage 0 and II while 9 cases were stage III. In arthroscopic exam, there were 17 cases of Outerbridge grade IV, 4 cases of grade III, 9 cases of grade II, 9 cases of grade I. The mean duration of pain was 5.3 months. In MRI, at least one finding of cleft in axial or coronal view or ghost sign in sagittal view was found in all cases. The shape of meniscus tears were blunt in 18 cases, transverse in 12 and degenerative tear in 10. Subtotal meniscectomy was performed in 16 cases, partial meniscectomy in 10 cases and meniscal repair in 14 cases. Conclusion : Medial meniscus posterior horn insertion tear occurs in patients over middle age is rarely related to trauma history but causes painful mechanical symptom and usually accompany arthritis. Meniscectomy can be done for the treatment but repair can be considered is some cases. Further study on the treatment result will be needed.

측후방 충돌 회피를 위한 조향 보조 토크 및 차등 제동 분배 제어 알고리즘 개발

이준영,김동욱,이경수,유현재,정혁진,고봉철,Lee, Junyung,Kim, Dongwook,Yi, Kyongsu,Yoo, Hyunjae,Chong, Hyokjin,Ko, Bongchul 한국자동차안전학회 2013 자동차안전학회지 Vol.5 No.2

This paper describes a coordinated control algorithm for rear-side collision avoidance. In order to assist driver actively and increase driver's safety, the proposed coordinated control algorithm is designed to combine lateral control using a steering torque overlay by Motor Driven Power Steering (MDPS) and differential braking by Vehicle Stability Control (VSC). The main objective of a combined control strategy is twofold. The one is to prevent the collision between the subject vehicle and approaching vehicle in the adjacent lanes. The other is to limit actuator's control inputs and vehicle dynamics to safe values for the assurance of the driver's comfort. In order to achieve these goals, the Lyapunov theory and LMI optimization methods has been employed. The proposed coordinated control algorithm for rear-side collision avoidance has been evaluated via simulation using CarSim and MATLAB/Simulink.