http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
모싯잎 채취 시기별 성분 함량, ACE 및 AChE 저해 활성
이종국,이정,조희제,김재경,최용민,Lee, Jong-Kug,Lee, Jeong,Cho, Hui-Je,Kim, Jae-Kyung,Choi, Youngmin 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.2
This study was performed to determine the optimal time of harvest for ramie leaves with the two varieties (Seocheon Seobang and Seoncheon Baekpi) by comparison of physiological activity and physicochemical characteristics. The crude protein, minerals, ascorbic acid, folate, chlorophyll, ACE inhibitory activity and AChE inhibitory activity were determined. The amount of crude protein in ramie leaf, which was collected in Seocheon-gun, Chungcheongnam-do, grew up steadily from early May to September. The content of calcium in was higher in Baekpi than in Seobang. Seobang displayed its highest value of 3,569.90 mg% in September, while Baekpi displayed its highest value of 3,163.84 mg% in October. Although, folate and vitamin C contents in the two varieties were slightly different, they were higher as the growth date grew in October. The highest value of chlorophyll content was observed in October, which was later in the vegetative state. ACE inhibitory activity and AChE inhibitory activity appeared to be higher in Baekpi than in Seobang. Between June and August, ACE inhibitory activity was highest in Baekpi variety.
모싯잎의 육성 계통별 성분 함량, 항산화 및 ACE 저해 활성
이종국,이정,조희제,윤혜경,김명석,Lee, Jong-Kug,Lee, Jeong,Cho, Hui-Je,Yoon, Hye-Kyung,Kim, Myung-Seok 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.2
Ramie (Boehmeria nivea M.) has been used for fiber materials in Korea traditionally, but in recent years, the concern with ramie leaves for the food industry such as tteok (a kind of Korean rice cake) industry has been increasing, so a study for eatable ramie is required for the expansion of ramie consumption. Moreover, the ramie varieties for the food industry are not established, so the natural species are cultivated in general; therefore, it is very important to select the ramie varieties for the food industry such as rice cakes, tea, beverage and so on. This study was undertaken to compare the physiochemical properties among 9 ramie lines selected in the Yeonggwang-gun Agricultural Technology Center to select the eatable ramie varieties for the food industry. The contents of the protein among 9 ramie lines was 6.21~7.56% and had the highest content in the YG55. The folic acid (folate) and vitamin C content had varying differences among the 9 lines; the content of folate showed $771.52{\sim}1,978.84{\mu}g%$, that of vitamin C showed 149.42~275.34 mg%. The ACE inhibitory activity appeared to be the highest in YG88 (21.5%) among the 9 ramie varieties tested.
지질분해효소 저해물질 함유 도둑놈의 갈고리 추출물의 영양특성 및 생리기능성
이종국 ( Jong Kug Lee ),강민구 ( Min Gu Kang ),이종수 ( Jong Soo Lee ) 한국식품영양학회 2011 韓國食品營養學會誌 Vol.24 No.2
This study was performed to develop new anti-obesity agents from medicinal plants for functional food industry. We prepared lipase inhibitor-containing ethanol extracts from Desmodium oxyphyllu DC. and its nutritional characteristics, stability of temperature and pH and physiological functionalities were investigated. Crude lipid content and curde protein content of ethanol extract from Desmodium oxyphyllum DC. were 26.5% and 5.7%, respectively and its asparagine content was 4,860 ㎎/100 g, dry basis. The ethanol extracts were also stable from pH 3.0 to pH 9.0 and below 80℃. The ethanol extract were showed high lipase inhibitory activity of 74.2% and acetylcholinesterase inhibitory activity of 68.4%.
도둑놈의 갈고리의 지질분해효소 저해물질의 정제 및 특성
이종국 ( Jong Kug Lee ),강민구 ( Min Gu Kang ),백승예 ( Seung Ye Baek ),안용근 ( Young Geun Ahn ),이종수 ( Jong Soo Lee ) 한국식품영양학회 2011 韓國食品營養學會誌 Vol.24 No.3
A lipase inhibitor from Desmodium oxyphyllum DC. was purified by methanol extraction, systematic solvent extraction, silica gel column chromatography, C18 solid phase extraction chromatography and RP-HPLC. We obtained the purified lipase inhibitor with 182 ng(IC50) of lipase inhibitory activity for a 0.06% yield. Its molecular weight was estimated to be 655.37 Da from an instrumental analysis of MALDI-TOF-MS and it was identified copper-3,5-dibromo-2-hydroxybenzoic acid (C14H8Br4CuO6) by 1H, 13C NMR analysis.
자궁경부 국소적 진행암에서 선행 화학요법으로서 Cisplatin , Ifosfamide , Paclitaxel ( CIP ) 의 phase Ⅱ 연구
윤석범(Seog Beom yOON),이종국(Jong Kug Lee),전섭(Seob Jeon),이지연(Ji Yeon Lee),최승도(Seung Do Choi),배동한(Dong Han Bae) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.10
목적 : 본 연구는 국소적으로 진행한 자궁경부 편평 세포암환자를 대상으로 Cisplatin,Ifosfamide, Paclitaxel(CIP)을 이용한 선행화학요법의 효과 및 독성을 연구하기 위한 목적으로 설정되었다 방법 : 1997년 2월부터 1999년 2월까지 자궁 경부 편평 세포암으로 확진된 40명(28 Ib2-IIa, 5 IIb, 4 IIIa, 2 IIIb, 1 IVa)의 환자를 대상으로 하였으며, 첫째날 paclitaxel 175mg/㎡를, 둘째날 cisplatin 50mg/㎡와 ifosfamide 5g/㎡, mesna 5mg/㎡를, 그리고 세째날 mesna 3mg/㎡을 투여하여 각 3주간 격으로 3회의 치료를 시행한 후 광범위 자궁적출술 및 임파선 절제술을 시행, 그 반응성을 조사하였다.결과 : 모든 40명의 환자의 임상적 반응율을 평가하였으며 또한 35명의 환자에서 수술을 시행하여 병리학적 반응율을 평가하여 으로 7예의 환자에서 완전 반응을 보였고 8예에서 적절한 부분 반응을 보였으며, 15예에서 미흡한 부분반응을, 5예에서 무반응양상을 보였고 평균 19개월간(15-31개월) 추적 조사한 결과 35예는 재발 없이 생존하였고, 4예에서 재발하였으며 나머지 1예는 사망하였다. 또한 독성에 관한 결과가 조사되었으나 그로 인한 심각한 합병증은 발생하지 않았다. 결론 : 국소적으로 진행된 자궁경부 편평 세포암에 있어서의 CIP regimen을 사용한 본 연구에서 병리학적 완전 반응 및 적정 부분 반응을 보인 경우는 37.5%로 나타났으며, 비교적 수용 가능한 범위 내에서의 독성 반응을 나타냈다. 앞으로는 본 약물을 이용한 선행화학 요법으로 질병의 진행여부 및 생존율 등 반응에 관한 좀 더 많은 예의 평가연구가 시행되어져야 할 것으로 생각된다. Objective : To evaluate the efficacy and toxicity of Cisplatin, Ifosfamide, Paclitaxel as neoadjuvant chemotherapy in 40 patients with locally advanced cervical squamous cell carcinoma.Methods : Forty patients with pathologic confirmed cervical squamous cell caner (28 Ib2-IIa, 5 IIb, 4 IIIa, 2 IIIb, 1 IVa) were prospectively enrolled in the study from Feb 1997 to Feb 1999. Patients with locally advanced squamous cell carcinoma were submitted to three courses of neoadjuvant chemotherapy (CIP) followed by surgery. Their treatment consisted of paclitaxel 175 mg/m2 given over three hours on day 1, cisplatin 50 mg/m2, ifosfamide 5 g/m2 in a 24-hour continuous infusion and mesna 5 g/m2 in a 24-hour continuous infusion on day 2 and mesna 3 g/m2 in a 24-hours continuous infusion on day 3. The course was repeated every three weeks for three courses and all of the patients excepted those with disease progression or who were inoperable, were scheduled for radical hysterectomy and pelvic lymphadenectomy.Results : All 40 patients were evaluated for response and toxicities. 35 patients underwent surgery, seven(17.5%) had pathology documented complete response, eight(20.0%) had partial responses with only microscopic residual disease in the cervix, fifteen(37.5%) had suboptimal partial responses and five(12.5%) had stable disease. And five(12.5%) patients had not performed surgery. The toxicities were studied and the results were evaluated with relatively acceptable range. At a median follow up period of 19 months(range 15-31 months), 35(87.5%) women are alive without recurrence, four are alive with recurrent disease and one died due to the disease. Conclusion : CIP regimen on the locally advanced cervical squamous cell carcinoma, yielded a 37.5% complete and optimal partial response rate with acceptable toxicity. And it should be done that adequate following up prospectively for determine the impact of CIP regimen in time to progression and survival.