우리시대 사진의 상황 : 무제 3 ( 이재갑 )

이재갑 현대사진영상학회 1998 우리시대 사진의 상황 Vol.- No.-

국내 시판 항생제의 허가 용량 및 용법의 적정성에 대한 고찰 : 국내 약제사용설명서(package insert)와 미국 Physicians' Desk Reference의 비교 Comparison of Domestic Package Inserts with Physicians' Desk Reference

이재갑,이연주,황병연,정혜원,정성주,김성범,정희진,김우주,김민자,박승철 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

목적 : 국내 시판중인 항생제의 1일 투여량과 투여간격의 적정성을 확인하고 적응증 및 중증도에 따른 항생제 용량 제시 여부를 확인하기 위하여 항생제 시판시 KFDA의 허가사항을 담은 약제사용설명서을 미국 FDA 공인 약제에 대한 사용지침으로 쓰이고 있는 PDR(Physicians' Desk Peference)과 비교하였다. 방법 : PDR에 등재되어 있는 항생제 중에서 시럽 및 도포용 항생제를 제외한 총 61종에서, 국내에 시판되어 있는 51종 항생제의 약제사용설명서를 대상으로 1일 투여량, 투약횟수, 적응증 및 중증도에 따른 설명 정도를 비교하였다. 결과 : 1) 1일 투여량 비교 : 비교 가능한 전체 항생제에서, 약제사용설명서가 PDR보다 적은 용량을 제시한 경우는 경구용 8종, 주사용 11종으로 총 19종(37%)였으며, 많은 용량을 제시한 경우는 경구용만 2(4%)종이었고, 동일하거나 비슷한 용량을 제시한 경우는 경구용 15종, 주사용 15종으로 총 30(59%)종이었다. 약제사용설명서에서 적은 용량이 제시된 항생제 중 경구용인 cefdnir, cefixime, cefpodoxime, ofloxacin, levofloxacin, norfloxacin(6종), 주사용인 cefazolin, cefotetan, ceftizoxime, meropenem (4종) 등 반수이상의 약제가 일본제약회사로부터 국내에 수입된 약들이었으며 일본의 약제 사용설명서와 동일한 용량을 제시한 것을 알 수 있다. 2) 투여간격 비교 : 비교가능한 항생제 51종 중에서 국내약제사용설명서가 PDR과 동일한 투약횟수, 투여간격을 제시한 항생제는 30종(59%)이었다. 국내 약제사용설명서가 PDR보다 적은 투약횟수, 긴 투여간격을 제시한 항생제는 9종(17%)이었다. 오히려 많은 투약횟수, 짧은 투여간격을 제시한 항생제가 12종(24%)이나 되었다. 경구용만 비교하였을 경우 국내 약제사용설명서가 PDR보다 적은 투약횟수를 제시한 항생제는 없었으며, 동일하세 제시한 경우는 15종, 빈번한 투약횟수를 제시한 경우는 10종이었다. 주사용 항생제에서 국내 약제사용설명서가 PDR보다 긴 투여간격을 제시한 항생제는 9종, 동일한 경우는 15종, 짧은 투여간격을 제시한 경우는 2종이었다. 3) 적응증 및 중증도에 따른 비교 : 약제사용설명서에서 적응증 또는 중증도에 따른 용량에 대한 설명이 부족한 경우는 경구용 13종, 주사용 7종으로 총 20종(39%)이었으며, PDR에서는 경구용 1종, 주사용 2종으로 총 3종(6%)이었다. 결론 : 항생제에 첨부되는 약제사용설명서 및 약제사용설명서를 바탕으로 편집되는 의약품집이 항생제를 처방하는 의사들이 용법과 용량을 결정함에 있어 참고 역할을 하고 있으나, 국내의 시판 허가사항을 담은 약제사용설명서가 많은 수에서 적응증 또는 중증도에 따른 1일 투여량과 투여간격에 대한 정확한 정보를 제공하고 있지 못하고 있다. Background : The appropriate usage of antibiotics needs informations such as its effectiveness for a given infection, administration route, the amount of effective dose, and the dose intervals. In this study, in order to find any significant discrepancy regarding to the details of explanation of the necessary information for appropriate antibiotic usages, we compares informations about 51 antibiotics, one from package inserts in Korea and the other from physician's desk reference (PDR) certified by FDA in the United States of America. Materials and Methods : Package inserts about antibiotics, only oral or parenteral agent, wereperused to collect three categories of data: the recommended dosage, dose interval, and adjustment of dose to indications or the severity of infection. These data available in Korea were compared with 61 antibiotics (32 oral and 29 parenteral agents) cited in PDR. Results : Package inserts for 51 antibiotics were gathered, because the remaining 10 antibiotics in PDR are not domestically commercialized. Among data on antibiotics comparable with those in PDR, 59% (30 cases: 15 oral and 15 parenteral agents) suggested the dose similar to that of PDR, 37% (19 cases: 8 oral and 11 parenteral agents) recommend less dose, and 4% in only 2 oral agents showed more dose. About half of the drugs recommending lower dosage were imported from Japanese pharmaceutical company, and the recommended doses of these antimicrobial agents were similar to those in Japan. About 59% (30 cases: 15 oral and 15 parenteral agents) directed dose interval or duration similar to those of PDR and 17% (9 parenteral agents) suggested less administration or longer duration. Surprisingly, in contrast to only 6% (3 cases) of PDR, 24% (12 cases : 10 oral and 2 parenteral agents) recommended more administration or shorter duration. About 39% (24 cases: 13 oral and 7 parenteral agents) revealed no information for dose adjustment commons to indications or the severity of infection. Conclusion : This study revealed that many guidelines in Korea recommend lower doses and/or unreasonable dose intervals. In future studies, improved antibiotic usage guidelines should be established based on pharmacokinetic and pharmacodynamic researches, on the aspect of optimal dosage, dose interval, and dose adjustment commensurate to the indications and the severity of the infection.

점착성의 탄력성 테이핑에 의한 시간별 피부자극 정도에 관한 연구

이재갑,노현영,김용권 한국지역사회건강관리협회 대한건강과학학회 2022 대한건강과학학회지 Vol.19 No.2

Background : Standards for preventing skin damage caused by physical and chemical stimulation of tape have been needed. Objective : The purpose of this study is to investigate the degree of skin irritation of taping over time and the appropriate application time. Methods : The skin reactivity was evaluated after we removed the tape at the inside of the upper arm after 1 hour, 4 hours, 12 hours, and 24 hours. Result : Four hours later, all participants had even a mild symptom of redness. Until 4 hours after taping, half of participants feel mild itching, but There were no more serious symptoms. However, waiting for 12 hours, two participants who felt mild itching complained moderate symptom and when we wait for 24 hours, two asymptomatic participants complained mild symptom. During study, 30% of participants felt burning sensation in the contact area overall six participants complained of tightness. and ,among them, four of participants felt it after 12 hours and the rest felt it after 24 hours. Conclusion : To lower the probability of adverse skin reactions,If it is difficult to accurately determine the skin condition,we thought that limiting the taping to about 4 hours is recommended.

“주민자치회와 지방의회 기능 중복 우려는 노파심일 뿐”

이재갑 한국자치학회 2019 월간 주민자치 Vol.95 No.-

역원근 테이핑의 신경생리학적 고찰

이재갑,최유진 한국지역사회건강관리협회 대한건강과학학회 2018 대한건강과학학회지 Vol.15 No.2

There are various approach of taping. Diversity in the taping approach makes it difficult to establish the grounded theory of taping. Therefore, it is necessary to classify the taping approach and establish each grounded theory. Orthopedic medicine taping, one of the taping approaches, include an approach called power source muscle taping. This text is intended for neurophysiological analysis of power source muscle taping. The power source muscle taping is very similar to kinesio taping. But it is not exactly the same. Power source muscle taping is only intended for pain only during movement. Therefore, power source muscle taping is only for muscles. Also, in the case of motion sickness, the organic damage of muscles also applies sports taping and excludes power source muscle taping. It is only intended for those with functional impairments of muscles. If the organic damage is repaired, it is subject to power source muscle taping. Methods of orthopedic taping include elasticity taping and cause taping. Elastic taping is attached on a muscle using elastic tape from origin to insertion. cause taping apply an inelastic tape to any part of the muscle. Use the form of cross tape and response point tape for cause taping. Taping attached to muscles can be distinguished by effects caused by physical effects and effects of stimulation. Kinesio tapping has presented the promotion of lymphatic flow by physical effects as the grounded theory. Even in orthopedic tape, the reduction in sensitivity of the muscle spindle due to physical effects was presented by Arikawa Isao. However, I argue that power source muscle taping is a facilitating effect of muscle tension caused by the stimulation effects of taping. Muscles with functional disabilities have some of the muscle fibers tensed in some areas, while others have been relatively less tense. In the end, the overall tension in the muscles is reduced. In this state, the movement causes pain by concentrating stress on the tense muscle fiber. Stimulation by power source muscle taping is carried to the thalamus through the posterior column, but before that, it is delivered to the anterior horn to excite the α-motor fiber and produce a reaction of autogenetic excitation that tensions the stimulated surrounding muscles. In conclusion, it is thought that increasing the overall tension of muscles with functional disabilities reduces pain.

COVID-19 Screening Center: How to Balance between the Speed and Safety?

이재갑 대한의학회 2020 Journal of Korean medical science Vol.35 No.15

When the H1N1 pandemic occurred in 2009, screening centers were set up in Korea as local hospitals organized temporary container offices outside the hospital buildings to screen for suspected influenza patients. During the Middle East Respiratory Syndrome corona virus (MERS-CoV) outbreak in hospitals in 2015, the government designated a specific hospital to diagnose and preempt quarantine patients with suspected MERS and pneumonia symptoms as a MERS-safety hospital. This MERS-safety hospital also operated a screening center.

Al-Fe-Ni 공정복합합금의 응고속도에 따른 전기저항의 변화

이재갑,조현기 경북대학교 산업기술연구소 1988 産業技術硏究誌 Vol.17 No.-

Numerous researchs have been investigated concerning the mechanism of unidirectionally solidification and the relationships between microstructure and growth rate in eutectic alloys. Although it is expected that the anisotropic microstructure associated with eutectic should produced the interesting electrical properties, almost all studies on eutectic composite alloy have been investigated about morphology, mechanical properties and thermal stability. In the present study, changes of electrical resistivity according to cooling rate in Al-Fe-Ni eutectic composite alloy is investigated. The obtained results are as follows; As cooling rate(R) increased, electrical resistivity of Al-Fe-Ni eutectic composite alloy at 520℃ increased with increaseing of fineness of eutectic fibers and formation of cellular structure. The higher the cooling rate, the higher the temperature dependence of electrical resistivity and the lower the stability of eutectic composite alloy, respectively.

변위에 의한 엉치엉덩관절의 기능장애를 위한 테이핑요법

이재갑,김명준,최영덕 한국지역사회건강관리협회 대한건강과학학회 2016 대한건강과학학회지 Vol.13 No.2

Sacroiliac joint was continued controversy over whether or not the presence of dysfunction. However, many studies have recently announced as the sacroiliac articulation disorders is increasing interest in. The movements of sacroiliac joint is nutation and counternutation, and then anterior-tilt and posterior-tilt. The movements of sacrum and ilium is coupled movement. Nutation problems of the sacrum can be solved by improving the posterior tilt of ilium, and the problem of counternutation can be solved through improvement of anterior tilt of ilium. Dysfunction of the sacroiliac joint is a primary factor in muscle imbalance, and a secondary factor in malposition of ilium and sacrum. Anterior tilt of Ilium is performed by contraction of rectus femoris, quadratus lumborum, and erector spinae, and posterior tilt is performed by contraction of hamstring, external oblique abdominis, and rectus abdominis. The primary goal of the taping approach to dysfunction of the sacroiliac joint is pain relief. Therefore, the taping method is determined by motion analysis that causes pain. 1. Is the disorder symmetric or asymmetric? 2. If there is a problem with Ilium, is there an anterior tilt problem or a posterior tilt problem? Or is there a problem with the nutation or a problem with the counternutation? 3. Whether to approach the primary factor or the secondary factor? Then, depending on your decision, select the method to apply in the following table. Pain pattern disfunction Primary factor (Muscle Stimulation Taping) Secondary factor (functional taping) Symmetry anterior tilt (both) rectus femoris erector spinae (both) anterior tilt facilitating posterior tilt (both) hamstring rectus abdominis (both) posterior tilt facilitating Asymmetry anterior tilt (affected side) rectus femoris, quadratus lumborum (opposite side) hamstring, externus oblique abdominis (affected side) anterior tilt facilitating (opposite side) posterior tilt facilitating posterior tilt (affected side) hamstring, externus oblique abdominis (opposite side) rectus femoris, quadratus lumborum (affected side) posterior tilt facilitating (opposite side) anterior tilt facilitating

최근 사례를 통해 본 (시술관련) 의료관련감염

이재갑 대한내과학회 2018 대한내과학회 추계학술대회 Vol.2018 No.2

세가지 다른 조건으로 형성시킨 비정질 실리콘에 대한 저온 열처리 결정화 기구

이재갑,진원화,이은구,임인권,Lee, Jae-Gap,Jin, Won-Hwa,Lee, Eun-Gu,Im, In-Gwon 한국재료학회 1996 한국재료학회지 Vol.6 No.3

세가지 다른 방법을 이용하여 형성시킨 비정질 실리콘(SiH4 a-Si, Si2H6 a-Si, Si+ implanted SiH4 a-Si)들에 대한 저온 결정화 기구의 차이를 고전적 이론인 Avrami 식(X=1-exptn, X=결정화 분율, t=열처리 시간, n=지수)을 이용하여 검토하였다. Silane으로 형성된 비정질 실리콘의 결정화 과정에서는 Avrami 식에서의 n의 값이 2.0을 나타내고 있어, 결정성장이 이차원적으로 이루어지면서 핵생성률이 시간에 따라 감소하고 있음을 알 수가 있었다. Si+ 이온 주입에 의하여 형성된 비정질 실리콘의 결정화에서는 3.0의 지수 값이 얻어지고 있어, 정상상태의 핵생성과 함께 2차원적인 결정 성장이 이루어지고 있었다. Disilane으로 형성된 비정질 실리콘에 대한 결정화에서는 2.8의 지수값이 얻어져, 정상상태의 핵 생성이 우세하게 일어나는 2차원적인 결정성장이 일어나고 있음을 알 수 있었다. 또한 TEM을 이용하여 시간에 따라 변하는 핵생성률을 조사하여, Avrami 식의 적용이 타당성 있음을 증명하였다. 마지막으로, 최종 입자의 크기가 열처리 온도에 크게 영향을 받고 있지 않음을 확인하였다.