http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이이형(Y . H . Lee),장준(J . Chang),이장훈(J . H . Lee),조용옥(Y . W . Cho),김성규(S . K . Kim),김기호(K . H . Kim) 대한내과학회 1987 대한내과학회지 Vol.33 No.4
N/A Tuberculosis is a chronic infectious disease. However it remains a very important preventable disease in Korean even though the prevalence rate has decreased from 5.1% to 2.2% since 1962 because of intensive efforts to eradicate it. While treatment for pulmonary tuberculosis is carried out mainly at local health centers, many patients are treated in private clinic and other hospitals as well. Since the university hospital is still one of the major control centers for patients with pulmonary tuberculosis, its contribution in the treatment of tuberculosis at one outpatient dispensary wae evaluated. We studied 315 outpatients, who visited Severance Hospital from January 1981 to December 1982, whose sputum tested postive for Mycobacterium tuberculosis, The results are as follows: 1) The mean age of total patients was 36.9 years, male to female ratio 1.3:1, and initial to retreatment case ratio l.2:1, 2) There were age range differences between initial and retreatment cases, with 43.1% of initial cases in the 2nd decade compared with retreatment cases where 25.5% were in the 2nd decade, 23.4% in the 3rd decade and 23.4% in the 4th decade, 3) There were 178 patients (56.5%) with negative sputum smear but positive culture, 130 patients (41.3%) with both smear and culture positive, and 7 patients (2.2%) with positive smear but negative culture, The rate of both smear and culture positive in retreatment cases (50.4% ) was significantly higher than in initial cases (33.9%). 4) Among 315 patients, 142 patients (45.1%) defaulted before 6 months treatment, and 173 patients (54.9%) were available longer than 6 months. 5) The mean age of the 142 early defaulters was 38.9 years, male to female ratio 1.5:1, and initial to retreatment case ratio 1.6:1. Of the above, 32 patients (22.5%) did not know the results of sputum culture. 6) Among the treatment group, 87 were initial cases and 86 were retreatment cases, and late defaulters in initial and retreatment ca were 15 (17.2%) and 12 (14. 0%), respectively. 7) The stabilization rates of initial and retreatment cases were 95.8%, 48.6%, respeetively and relapse rates after 2 years follow up were 5.8%, 19.4%, respectively. 8) There were significant differences in negative conversion rate of sputum AFB between initial and retreatment cases, and the rates after 1,3,6 months of therapy in initial cases were 27.6%, 52.9%, 94,3% and those in retreatment cases 9.3%, 22.1%, 34.9%, respectively. 9) The mean age of relapse cases was 34.9 years, male to female ratio 1,2:1, and initial to retreatment case ratio 1:1.7. The relapse interval calculated from the end of treatment ranged from 3 months to 13 months, and 6 cases (54.5%) relapsed within 6 months after the end of treatment.
비소세포폐암에서 p53유전자의 구조적 이상 및 단백질 발현이 예후에 미치는 영향
이이형 ( Y. H. Lee ),신동환 ( D. H. Shin ),김주항 ( J. H. Kim ),임호영 ( H. Y. Lim ),정경영 ( K. Y. Chung ),양우익 ( W. I. Yang ),김세규 ( S. K. Kim ),장준 ( J. Chang ),노재경 ( J. K. Roh ),김성규 ( S. K. Kim ),이원영 ( W. Y. Lee ) 대한결핵 및 호흡기학회 1994 Tuberculosis and Respiratory Diseases Vol.41 No.4