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산처리(酸處理)에 따른 상아질(象牙質)에 대한 Glassionomer Cement의 접착강도(接着强度)에 관(關)한 실험적(實驗的) 연구(硏究)
이원섭,민병순,최호영,박상진,Lee, Won-Seob,Min, Byung-Soon,Choi, Ho-Young,Park, Sang-Jin 대한치과보존학회 1988 Restorative Dentistry & Endodontics Vol.13 No.1
The purpose of this study was to evaluate the bond strength of glassionomer cement against cut dentin surface which was treated with various surface cleaning agents. 48 freshly extracted human 3rd molars were ground flat through the enamel into the dentin using 600 grit silicone carbide paper under a flow of water. The were divided into four groups by the following cleaning procedure on cut dentin surface; Group I : No surface treatment after grinding with 600 grit silicone carbide paper as control group Group II : Surface treatment with 50% citric acid for 30 seconds. Group III : Surface treatment with 37% phosphoric acid for 30 seconds. Group IV : Surface treatment with 10% poly acrylic acid for 30 seconds. The specimens in 4 groups were immersed in distilled water at $37^{\circ}C$ for 24 hours before testing after cleanising with water-spray and drying with air. Bond strength was measured with Instron Universal Testing Machine (Autograph S-100, Shimadzu, Kyoto, JAPAN). The results were as follows: 1. The bond strengths of group II, III & IV were not seemed to be shown more significant improvement than a group I. 2. The bond strengths in groups which were treated with 50% citric acid, 37% phosphoric acid and 10% polycrylic acid, were ranked 24.70kg/$cm^2$, 22.02kg/$cm^2$ and 31.13kg/$cm^2$, but its difference was not significant, statistically.
Ice Ball을 이용한 빙축열조 내의 열유동 특성에 관한 연구
이원섭 한국기계기술학회 2015 한국기계기술학회지 Vol.17 No.2
The study on ice thermal storage system is to improve total system performance in actual air-conditioning facilities. This paper deals with experimental research to observe the characteristics of heat flow and the effect of ice thermal storage in case of three sizes of ice ball, which are included identification of ice thermal extraction. Diameters of three ice ball was 103mm, 96mm, and 76mm is equivalent to 0.45, 0.50 and 0.55 in porosity respectively. Also inlet geometric parameters are the perforator and distributor. Flow rate of brine were 2LPM, 4LPM and 6LPM and the temperature difference in dynamic parameter are 8℃, 10℃ and 12℃. Flow rate of brine used the liter per minute(LPM) for liquid measurement applications. The effect of brine flow rate on efficiency increased as the temperature difference and porosity increased. An adaption of a long-term storage in case of smaller porosity(ɛ=0.45) was available through experiments of outlet temperature responses.
이원섭,이상미,Jeong Won Yun,정지현,김동훈,김혜정,장성환,김곤섭,류충호,신성철,홍순찬,최영현,정진명 대한암예방학회 2014 Journal of cancer prevention Vol.19 No.1
The extract of Allium cepa Linn is commonly used as adjuvant food for cancer therapy. We assumed that it includes a potential source of anti-cancer properties. Methods: We investigated anti-cancer effects of polyphenols extracted from lyophilized A. cepa Linn (PEAL) in AGS human cancer cells. Results: PEAL inhibited cell growth in a dose-dependent manner. It was related to caspase-dependent apoptosis. We confirmed this finding with annexin V staining. PEAL up-regulated p53 expression, and subsequent Bax induction, down regulated Bcl-2 protein, anti-apoptotic protein. In addition, PEAL suppressed Akt activity and PEAL-induced apoptosis were significantly accentuated with Akt inhibitor (LY294002). Conclusions: Our data suggested that PEAL induce caspase-dependent apoptosis through mitochondrial pathway by up-regulating p53 protein, and subsequent Bax protein as well as by modulating Bcl-2 protein, and that PEAL induces caspase-dependent apoptosis at least in part through the inhibition of phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway. This study provides evidence that PEAL might be useful for the treatment of cancer.