간이 신경 인지기능 국재화 검사의 개발 I : 고안

이영호,정효경,허시영,고영택,박병관,Lee, Young-Ho,Jung, Hyo-Kyung,Hoe, Si-Young,Koh, Young-Taek,Park, Byung-Kwan 대한수면의학회 1999 수면·정신생리 Vol.6 No.2

Recently, with increasing the number of patients with head injury and cerebrovascular accident, there has been an increasing need for the useful assessment tools of brain dysfunction and it's localization. With the advances in the neuroscience since the mid-1970s, particularly in the areas of neuroanatomical tracing, neuroimaging, and improved behavioraltest design, it has been possible to develop a more precise understanding and localization of brain dysfunction. However, these equipments are not readily available in the private clinics and too expensive to use as a screening tool to all suspected patients with brain dysfunction. Although several screening tests such as Mini-Mental States Examination(MMSE) or Brief Cognitive Rating Scale(BCRS) are simple in use and useful for the brief assessment of brain dysfunction, these are also limited in using for localization of brain dysfunction because of their simplicity. With increasing need of the assessment tool which is able to localize the dysfunction more precisely in the clinical practice, we planned to develop the new assessment tool, the Bedside Neurocognitive Function Localization Test(BNLT) which is suitable for this purpose. The BNLT was designed to be utilized for localizing brain dysfunction effectively and readily in the clinical practice. We introduced the whole process of designing the BNLT in this manuscript.

비외상성 피질하 뇌혈관 질환 환자에서 인지기능, 정신행동 증상 및 일상 생활 기능간의 상관에 대한 연구

이영호,박영수,최홍,최영희,고대관,정영조,박병관,김수지,정숙희,고병희,송일병,박건우,이대희,Lee, Young-Ho,Park, Young-Soo,Choi, Hong,Choi, Young-Hee,Ko, Dae-Kwan,Chung, Young-Cho,Park, Byoung-Kwan,Kim, Soo-Ji,Chung, Suk-Hai,Ko, Byoung-Hee,So 한국정신신체의학회 1996 정신신체의학 Vol.4 No.2

Objective : This study was tried to investigate the specific relationships among cognitve function, neurbehavioral symptoms, and daily living functions, as well as provide the guidline of more proper clinical approches for patients with subcortical cerebrovascular disease. Objects and Methods Subjects were 85 patients whose diagnosis was confirmed by brain CT or MRI and controls were 195 normal persons matched by educational level with the subjects. The cognitive functions were evaluated by BNA(Benton neuropsychiatric assessment), subjective neurobehavioral symptoms by SCL-90-R(Sympton Check List-90-Revised), objective neurobehavioral symptoms by NRS(Neurobehavioral Rating Scale), and daily living function symptoms by NRS(Neurobehavioral Rating Scale), and daily living function by GERRI(Geriatric Evaluation by Relative's Rating Instrument) and IADL(Instrumental Activities of Daily Living Scale). Results: 1) Subjects showed significantly lower cognitive functions than controls in all tests of BNA except Lt-Rt Orientation Test(p=0.09) and facial Recognition Test(p=0.186). 2) In subjective neurobehavioral symptoms, subjects showed significantly lower scores in all symptoms except anxiety(p=0.059), hostility(p=0.159), and phobic anxiety(p=0.849). But in objects neurobehavioral symptoms, subjects showed significantly higher in scores in psychoticism (p=0.000) and neuroticism(p=0.025) of NRS. 3) The score of social functioning of GERRI(p=0.000) and that of IADL(p=0.000) were significantly higher in subjects than in controls. 4) for correlation between cognitive and daily living functions, there were significant correlations between the scores of all items on BNA and the score of cognitive or social function of GERRI and the socre of MDL in corntrols, whereas in subjects, there were significant correlations only between the scores of BNA and the score of IADL. 5) for correlation between neuroehavioral symptoms and daily living functions, there were significant correlatons between the socre of subjective neurobehavioral symptoms and the scores of all subscales of GERRI and the score of MDL in controls. On the contrary, in subjects, there were significant correlations between the score of social function of GERRI and the score of objective neurobehavioral symptoms such as psychoticism, agitiation-hostility, and decrease d motivation-emotional withdrawl. Conclusion : Above results suggest that disturbances in specific function of brain may play a role as a predictor of impairments with specific daily living functions and also suggest that specific correlations among various functions may be useful as clinical parameters for setting of the treatment goal and for assessing the ongoing process in the treatment and rehavilitation of the patients with subcortical cerebrovascular disease.

고령화 사회 환경 변화에 대응하는 정보통신 산업 비즈니스 모델 설계

이영호,김영욱,김영진,김혜원,이정민,Lee, Young-Ho,Kim, Young-Wook,Kim, Young-Jin,Kim, Hye-Won,Lee, Jeong-Min 한국경영과학회 2006 經營 科學 Vol.23 No.3

In this paper, we develop the business model of telecommunication company that facilitates to explore new business opportunities on aging society. Considering the trend of aging society, we analyze the market drivers of senior market. Analyzing market dynamics and value chain, we design a set of business models for telecommunication company. In addition, we describe the evolution path of the proposed business model in terms of technology development and market. Finally, we develop a framework for evaluating the effectiveness of the business model.

Broadband Convergence Network 가입자 망 설계 시스템 연구

이영호,정진모,김영진,이순석,박노익,강국창,Lee, Young-Ho,Jung, Jin-Mo,Kim, Young-Jin,Lee, Sun-Suk,Park, No-Ik,kang, Kuk-Chang 한국경영과학회 2006 經營 科學 Vol.23 No.2

In this paper, we consider a network optimization problem arising from the deployment of BcN access network. BcN convergence services requires that access networks satisfy QoS meausres. BcN services have two types of traffics : stream traffic and elastic traffic. Stream traffic uses blocking probability as a QoS measure, while elastic traffic uses delay factor as a QoS measure. Incorporating the QoS requirements, we formulate the problem as a nonlinear mixed-integer Programming model. The Proposed model seeks to find a minimum cost dimensioning solution, while satisfying the QoS requirement. We propose two local search heuristic algorithms for solving the problem, and develop a network design system that implements the developed heuristic algorithms. We demonstrate the computational efficacy of the proposed algorithm by solving a realistic network design problem.

심인성 소양증환자와 만성 담마진환자의 스트레스지각과 통제소재 및 우울증상과의 관계

이영호,고대관,한기석,정영조,김용상,임성춘,남기흠,김중호,Lee, Young-Ho,Ko, Dae-Kwan,Han, Ki-Seok,Chung, Young-Cho,Kim, Yong-Sang,Lim, Sung-Chun,Nam, Ki-Heum,Kim, Chung-Ho 한국정신신체의학회 1995 정신신체의학 Vol.3 No.2

For investigating a disease specific psychological mechanism in various dermatological disorders, we tried to explore the difference in correlation among stress perception, locus of control as a coping strategy, depressive symptoms and pruritic symptoms in the patients with psychological pruritis and chronic urticaria. The subjects were composed of 32 patients with psychol-ogical pruritis and 67 patients with chronic urticaria(subject group), and 25 patients with organic pruritis and 59 patient with major depression(control group). Global assesment of recent stress scale(GARS), I-E locus of control scale, Beck Depression Inventory(BDI) and medical college of wisconsin center pain follow up questionnaire were used for assesement. The results were as follows: 1) There were a significant positive correlation between stress perception and depressive symptom in patients with psychological pruritis, chronic urticaria, and major depression but not hi organic pruritis. 2) In relationship between locus of control and depressive symptom, patients with psychological pruritis, organic pruritis, and major depression except chronic ruticaria showed a significant negative correlation. 3) For intensity and pattern of pruritis, there were positive relations with depressive symptom and stress perception only in patients with chronic urticaria. Above results indicate that stress perception and locus of contorl may play a significant role in the formation of psychological and dermatological symptoms in psychological pruitis and chronic urticaria. But the mechanisms of these processes are different in either disorder.

지르코늄 합금 관의 임계좌굴 압력 산정을 위한 최소안전율

김형규(Hyung-Kyu Kim),김재용(Jae-Yong Kim),윤경호(Kyung-Ho Yoon),이영호(Young-Ho Lee),이강희(Kang-Hee Lee),강흥석(Heung-Seok Kang) 대한기계학회 2011 大韓機械學會論文集A Vol.35 No.3

얇은 관 탄성좌굴 공식의 불확실성을 고려하기 위해, 공식을 구성하는 파라미터인 튜브재료의 탄성계수, 푸아송 비, 튜브 두께 및 지름의 불확실성을 분석하였다. 본 연구는 원자로에서 연소되는 핵연료봉과 같이 사용 중 함몰을 엄격히 방지하고 있는 얇은 관의 설계신뢰도를 향상시키는 데에 중요하다. 분석 방법은 각각의 파라미터가 변화할 수 있는 범위를 충분히 포함할 수 있는 최소의 탄성좌굴 안전율을 구하고 이를 선형적으로 합하여 최종의 최소안전율을 구하였다. 최소 안전율에 가장 큰 영향을 미치는 파라미터는 관의 두께로 나타났다. 두께가 얇을수록 더 큰 최소안전율이 필요하며 예로 적용한 지르코늄 합금관의 경우, 두께가 0.254 와 0.87 ㎜ 일 때 최소안전율은 각각 1.547 과 3.487 로 나타났다. We consider the uncertainty in the elastic buckling formula for a thin tube. We take into account the measurement uncertainty of Young’s modulus and Poisson’s ratio and the tolerance of the tube thickness and diameter. Elastic buckling must be prohibited for a thin tube such as a nuclear fuel rod that must satisfy a self-stand criterion. Since the predicted critical buckling pressure overestimated that found in the experiment, the determination of the minimum safety factor is crucial. The uncertainty in each parameter (i.e., Young’s modulus, Poisson’s ratio, thickness, and diameter) is mutually independent, so the safety factor is evaluated as the sum of the inverse of each uncertainty. We found that the thickness variation greatly affects the uncertainty. The minimum safety factor of a thin tube of Zirconium alloy is evaluated as 1.547 for a thickness of 0.87 ㎜ and 3.487 for a thickness of 0.254 ㎜.

Zirconium 합금 관 임계좌굴 압력의 불확실성에 따른 최소안전율

김형규(Hyung-Kyu Kim),김재용(Jae-Yong Kim),윤경호(Kyung-Ho Yoon),이영호(Young-Ho Lee),이강희(Kang-Hee Lee),강흥석(Heung-Seok Kang) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.11

Uncertainty of the elastic buckling formula of a thin tube is considered. The measuring uncertainty of Young’s modulus and Poisson’s ratio and the tolerance of the tube thickness and diameter are dealt with. The elastic buckling should be absolutely prohibited for a thin tube like a nuclear fuel rod that should satisfy a self-stand criterion. Since the predicted critical buckling pressure overestimated the actual one observed from an experiment, determination of the minimum safety factor is crucial. The uncertainty of each parameter (i.e., Young’s modulus, Poisson’s ratio, thickness and diameter) is mutually independent, so the safety factor is evaluated as the sum of the inverse of each uncertainty. It is found that the thickness variation strongly affects the uncertainty. The minimum safety factor of a thin tube of Zirconium alloy needs to be from 1.547 to 3.487 for the thickness of 0.87 and 0.254 ㎜, respectively.

식사 행동의 신경학 : 섭취에 중점을 맞추어서

이영호,Lee, Young Ho 대한생물정신의학회 1998 생물정신의학 Vol.5 No.2

In mordern society, nutritional and appetite disorders occur in epidemic proportions and are serious health harzards. Obesity and diabetes affect over 30% of American population, while eating disorders, such as anorexia nervosa and bulimia nervosa occur in a growing number of adolescences and young adults. The changes in various sociocultural aspects with the introduction of Westernized culture have had the effect of increasing the risk of same problems in Korea. Disorderd eating patterns are a primary symptom of numerous psychiatric disorders and loss of appetite and cachexia, during illness or in the elderly, preclude proper medical treatment for restoring good health or preserving life. Increased understanding of the systems of the body and brain, related to energy and nutrient balance, may help us to treatment and ultimately prevent these commom disorders. In this review, the author highlights the psychobiological mechanisms or factors which are associated with eating behavior, especially in the view of intake psychobiology. This review would be concentrated on 1) the theoretical concepts and theories of eating behavior ; 2) the psychobiological determinants of food intake ; and 3) the psychobiological control of eating behavior.

신체화의 생물학적 기전 : 신체화의 신경심리학적 모델을 중심으로

이영호,Lee, Young-Ho 한국정신신체의학회 2000 정신신체의학 Vol.8 No.1

Somatization disorder is a chronic condition characterized by multiple somatic complaints that are not due to any apparent organic illness. Somatization disorder is related historically to hysteria and hysteria has been defined by the existence of somatic complaints for which no organic reason can be found. Therefore most theories of somatization have focused on the psychodynamic and sociological perspectives. However, the concept that the somatic presentation of emotional distress or psychiatric illness might have a neurobiological basis has also aroused considerable interest. Relative to this perspective, the case of Anna O. which has been considered the prototype of hysteria, was reformulated from a neuropsychological perspective. Several neurophysiological and neuropsychological studies, studies concerning hemispheric differences in symptom presentation of the patients with hysteria have been shown the evidences for the biological basis of somatization. Moreover, recent neuroimaging studies in somatization disorder also show that brain dysfunction in somatization. The author reviewed several candidate theories which could help to explain the process of somatization in the perspective of biological basis and proposed the new neuropsychological model of somatization. The author also examined the possible application of this model to the treatment of somatization disorder and discussed it's limitation and the future directions in this field. 신체화 장애란 명백한 기질적 병리가 없이 다양한 신체 증상을 호소하는 만성 장애를 말한다. 그런데 신체화 장애는 역사적으로 기질적인 이상이 없이 신체적인 증상이 나타나는 히스테리와 연관이 있다고 알려져 왔다. 따라서 신체화와 관련된 대부분의 이론들은 주로 정신역동이나 사회적인 관점에 초점이 맞추어져 왔다. 그러나 감정적인 문제나 정신질환이 신체화로 나타나는 기전에서 신경생물학적인 관점에 대한 관심 또한 적지 않았었다. 이런 신경생물학적인 관점에서 히스테리아의 원형으로 알려져 있는 Anna O 증례조차도 신경심리학적인 관점에서 재조명되기도 하였다. 몇몇 신경생리학적 및 신경심리학적 연구결과들, 히스테리 환자에서 신체화증상 표현의 좌우 반구차이에 대한 연구결과들이 신체화의 생물학적 근거를 뒷받침해 주고 있다. 최근 들어 신체화 장애의 신경영상검사는 신체화 장애에서 뇌의 기능 이상이 존재함을 보여 주고 있다. 이에 저자는 생물학적 관점에서 신체화의 과정을 설명해 줄 수 있는 몇몇 가설들을 고찰하고 이를 바탕으로 신체화에 대한 새로운 신경심리학적 가설을 제시하고자 한다. 이와 함께 이 가설을 신체화 장애의 치료에 어떻게 적용시킬 수 있을까도 논의하고 이 가설의 제한정과 이 영역에 있어 앞으로의 발전 방향에 대해서도 논의하려고 한다.

긴장재를 사용하지 않은 프리캐스트 교각의 내진성능 실험 연구

이영호,송재준,Lee,Young Ho,Song,Jae Joon 한국방재학회 2012 한국방재학회논문집 Vol.12 No.6

본 논문은 PC 텐던 등에 의한 긴장력을 도입하지 않고 일반 철근만을 사용한 프리캐스트 교각의 내진성능을 검증하기 위하여 프리캐스트 교각의 실물모형 내진성능 실험을 실시하였다. 프리캐스트 블록은 축방향 철근 3개를 하나의 홀로 삽입되도록 하여 시공성을 향상시켰다. 프리캐스트 유무와 FRP보강 유무를 실험변수로 하여, 동일한 형상의 3개의 실험체에 대하여 실험을 실시하였고, 파괴형상, 반복 횡하중에 대한 연성능력을 평가하고 각 시험체의 강성저하에 따른 감쇠비, 강성 저감과 소산에너지 등을 비교하였다. 실험결과, 프리캐스트 교각의 시공성과 내진성 및 FRP 보강에 의한 내진성능 향상을 확인할 수 있었다. In this study, the tests of seismic performance for full-scale models of the precast pier were conducted in order to verify the seismic performance of the precast pier using general rebar without introducing prestressing force such as a PC tendon. The constructability of the precast blocks was improved by inserting three rebars on an axis direction into a one hole. The tests for three piers with identical form were carried out, with use of precast and FRP reinforcement as test variables. The ductility for failed shape and cyclic transverse loads was evaluated. The damping ratio, stiffness reduction, and energy dissipation according to reducing stiffness were compared. These tests proved improvement of constructability and seismic performance for precast pier and of seismic performance for FRP reinforcement in their results.