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      • KCI등재

        개혁주의생명신학의 성경적 토대 모색 : 개혁주의생명신학과 이단 문제 -개혁주의생명신학의 토대인 칼빈 신학의 입장에서 본생명을 죽이는 이단 사상

        이숭구 ( Seung Goo Lee ) 개혁주의생명신학회 2010 생명과 말씀 Vol.2 No.-

        개혁주의생명신학의 과제 가운데 하나로 생명을 죽이는 이단 사상이 과연 어떤 것인지를 분명히 드러내는 것이 필요하다고 여겨진다. 이 글에서는 일단 교회사에서 나타났던 명백한 이단들에 대한 칼빈의 견해를 생각해 보고, 칼빈 시대에 나타난 잘못된 사상과 실천에 대한 칼빈의 견해를 이끌어 낸 후에, 성경을 잘못 해석하면 이런 이단이 융성할 수 있도록 하는 분위기를 마련하는 몇 가지 본문들에 대한 칼빈의 견해를 명확히 함으로써 많은 분들이 이단이냐 사이비적 방향으로 나아가지 않도록 하기 위한 토대를 마련하는 일을 시도하였다. 이 논의는 단순히 어떤 것이 이단인지 아니지를 알아보기 위한 것이 아니라, 우리가 어떻게 하면 가장 바람직한 신앙생활을 할 수 있을지를 제시하기 위한 것이며, 또한 우리 주 변에 이단 사상들은 물론이거니와 사이비 신앙적 요소가 근절되도록 하기 위한 목적으로, 즉 우리의 신학적 활동이 진정한 생명 신학이 되도록 하려는 목적을 가진 것이다. One of the tasks of the Reformed Life theology is to identify the heretical thoughts that destroy the spiritual life of the believers. In this paper I examined John Calvin`s view of the heresies. I drew out Calvin`s criticism on the heretical ideas and heretical practices appeared in Calvin`s days. This discussion is not merely to point out what are the prevaling heretical ideas of Calvin`s day, but also to help the saints to have a faithful life and to help our theology to be a true life theology by discarding distorted interpretations of the Scriptures.

      • 염화 제2수은이 흰쥐 신장에서의 지질 과산화와 Catalase 활성도에 미치는 영향

        이숭구,하경란,고현철,신인철,서대규 한양대학교 의과대학 1994 한양의대 학술지 Vol.14 No.2

        In an attempt to define the early biochemical determinants that participate in the pathogenesis of mercuric chloride-induced nephrotoxicity, especially focusing on oxygen free radicals, we studies malondialdehyde(MDA) level and catalase activity in renal cortex of the rats at 24, 48 and 72 hr after the injection of mercuric chloride. Wistar albino rats weighing 180 to 220gm were injected subcutaneously with mercuric chloride(HgCl₂, 2mg/kg). The result obtained can be summarized as follows: 1.The group treated with mercuric chloride showed significantly lower MDA level at 24, 48 and 72hr after the infection as compared to that of control group. 2.The group treated with mercuric chloride showed significantly higher catalase activity at 24hr and lower catalase activity at 72hr after the infection as compared to that of control group. These results suggest that the excessive oxygen free radicals resulting from the depression of catalase activity is an important determinant in pathogenesis of mercuric chloride-induced nephrotoxicity.

      • KCI등재후보

        활동성폐결핵 환자의 치료에 따른 67Gallium 폐주사의 음전시기의 의의 ( 제 2 보 )

        이숭구(Sung Ku Lee),이윤하(Yoon Ha Lee),김진곤(Jin Gon Kim),서대원(Dae Won Soe),장태종(Tae Jong Jang),김윤권(Yun Kwon Kim),김소연(So Yon Kim),박병익(Byong Yik Park),이권전(Gwon Jun Lee) 대한내과학회 1995 대한내과학회지 Vol.49 No.2

        N/A Objectives: In the treatment of active pulmonary tuberculosis, it is difficult to determine when the active tuberculosis has became inactive. (67)Gallium lung scan is known to be useful in the diagnosis of active pulmonary tuberculosis. The grade of Galliumuptake, the time of loss of uptake and the relation to the stability of tuberculous lesion in the chest radiograph were followed to define the possibility of making early decision when active pulmonary tuberculosis became inactive Metheds: In 31 patients with active pulmonary tuberculosis, (67)Galliurn lung scan and chest radiograph were followed serially from June 1991 to October 1993. (67)Gallium lung scan and chest radiograph were followed serially from June 1991 to October 1993, (67)Gallium lung scan was performed 48 hours after intravenous injection of 3mCi of (67)Gallium citrate and classified into 4 grades according to the degree of up- take. Results: 1) In patients with active pulmonary tuberculosis, the grade of Gallium uptake in lung scan was proportional to the severity of lesion in chest radiograph. 2) The degree of (67)Gallium uptake in serial lung scan waned progressively while antituberculous chemotherapy was continued, and showed in loss of uptake in 83% of patients within 6 months of therapy 3) The loss of (67)Gallium uptake was observed simultaneously in most patients as the lesion in chest radiograph became stable. In 81% of patients, the interval between the time of loss of (67)Gallium uptake and Radiologic stabilization was less than one month. Conclusion : While antituberculous chemotherapy was given, the serial (67)Gallium lung scan might be useful in determining the activity of tuberculous lung lesion and in making earlier decision than chest radiograph. Conclusively, we consider Gallium lung scan as a valuable measure in assessing the effectiveness of antituberculous treatment.

      • SCOPUSKCI등재

        복막투석액의 저류가 위배출시간에 미치는 영향

        오하영,오동진,김범,이숭구,김윤구,강우헌,이방훈,김혜영,허우성,김대중 대한신장학회 1998 Kidney Research and Clinical Practice Vol.17 No.6

        We evaluated gastric emptying time(GET) by using Tc99m-sulfur colloid gastric emptying scintigraphy in 11 patients with CAPD(6 male, 5 female) and 14 healthy volunteers. We investigated the effect of dialysate dwelling on GET by studying twice, once without dialysate in the abdomen(drained) and once with 2 L of dialysate in the abdomen(full), and the relationship between body surface area(BSA) and delayed gastric emptying. 1) The mean of gastric emptying rate in 120 minute in patients with CAPD when drained(67.8±13.4%) was not different from that in healthy volunteers(65.4±8.6%) 2) The mean of gastric emptying rate in 120 minute when full(55.6±14.6%) was significantly lower than that when drained(67.8±13.4%)(P$lt;0.05). In four of the 11 patients(36.4%), gastric emptying was extremely delayed from normal to abnormal range when full. 3) The BSA(1.5±0.11m2)of patients who had extremely delayed GET from normal to abnormal range was smaller than that(1.74±0.22m2) of patients who had minimal delayed or unchaET when full. This study showed the patient with CAPD had normal gastric emptying when drained, and that gastric emptying was delayed by dialysate dwelling, especially in the patients who has less than 1.5m2 of body surface area. Therefore, we suggest that intermittent nocturnal peritoneal dialysis or a small volume of dialysate may be considered for the patient with small body surface area based on the adequacy.

      • SCOPUSKCI등재

        한국인에서 혈청 크레아티닌을 이용한 크레아티닌 청소율의 계측

        김대중,오하영,오동진,김범,이숭구,서기현,강우헌,이방훈,김혜영,이윤하,허우성,김윤구 대한신장학회 1998 Kidney Research and Clinical Practice Vol.17 No.6

        Cockcroft and Gault's formula is frequently used to estimate creatinine(Ccr) in clinical practice. To determine the accuracy of such estimation in Korean patients, we measured simultaneously, serum creatinine and 24-hour urinary creatinine excretion in 696 Korean patients(male:350, female:346). Measured Ccr was significantly different from estimated Ccr in several age groups and the decrease of creatinine excretion with age is less than Cockcroft and Gault's estimation. We assumed that this difference can be due to difference of the body habitus and difference of urinary creatinine excretion per body weight between different races. So we divided the sample population into two groups and derived the new formula in one group with regression analysis between age and 24 hour urinary creatinine excretion per body weight for estimation of Ccr as Cockcroft and Gault derived their formula and applied it to another group to compare the new formula with Cockcroft and Gault's formula in Korean patients. The new formula was Ccr(mL/min)=[(260-age)?weight(kg)]/[160?serumCr(mg/dL)] for male and Ccr (mL/min)?[(236-age)?weight(kg)]/[180?serum Cr(mg/dL)] for female. Predictive accuracy of the new formula was significantly better than the Cockcroft and Gault's formula in the other sample population and also in subgroup of the patients with azotemia.

      • SCOPUSKCI등재

        β2-microglobulin의 복막이동 특성 및 복막 청소율에 관한연구

        문지현,김대중,오하영,이숭구,이방훈,채영숙,김범,오동진,허우성,김윤구,강우헌 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.4

        In addition to CAPD, various modalities of peritoneal dialysis such as CCPD and NIPD have been introduced recently. The adequacy in these peritoneal dialysis has been evaluated by clearance of small molecular weight solutes such as creatinine(molecular weight 113 Dalton) and urea(molecular weight 60 Dalton). The middle molecular weight solutes(molecular weight 3,000 to 12,000 Dalton) have been regarded as one of the uremic toxins. Relatively larger clearance of middle molecular weight solutes is one of the advantages of CAPD compared with HD. Although peritoneal transport of middle molecular solutes can be different from that of small molecular weight solutes because of its size, there are a few reports about peritoneal transport characteristics and clearance of middle molecular weight solutes in various modalities of PD. We wanted to analyze peritoneal transport characteristics and clearances of middle molecular weight solute in various modalities of peritoneal dialysis in comparison with small molecular weight solutes. To evaluate the potential differences in peritoneal transport characteristics and clearances of middle and small molecules in CAPD, CCPD and NIPD, we compared transport characteristics and clearance of β2-MG and creatinine. 35 CAPD patients, 9 CCPD patients, 7 NIPD patients were included in the study, who were clinically stable for at least one month without peritonitis. he β2-MG concentrations in serum and dialysate as measured by radioimmunoassay. Standard peritoneal equilibration test and a weekly peritoneal clearance for creatinine and β2-microglobulin were used. The results were as follows: 1)Dialysate to plasma ratio of β2-MG were 0.11±0.03, 0.13±0.05, 0.10±0.02, 0.08±0.03, respectively in high(N=6), high average(N=13), low average(N= 14), low(N=7) group according to PET. There were significant differences between high average and low average, high average and low group(p$lt;0.05). Correlation between D/Pβ2-MG ratio and D/Pcr ratio was significant(spearman's p=0.453, p$lt;0.05). 2)Ipatients, peritoneal creatinine and β2-MG clearance were 48.9, 8.2L/wk, respectively and there was a weak correlation between them (Spearman's p=0.294, p$lt;0.05). 3)The peritoneal creatinine clearance were 48.9, 41.0, 35.9L/wk and ?2-MG clearance were 8.2, 5.5, 4.1L/wk, respectively in CAPD, CCPD and NIPD. The ratio of peritoneal β2-MG clearance to creatinine clearance were 0.16, 0.14, 0.11, respectively in CAPD, CCPD and NIPD. Peritoneal β2-MG clearance in APD such as CCPD and NIPD is lesser than that in CAPD. In conclusion, peritoneal transport characteristics for β2-MG differ from that for creatinine, although peritoneal clearnce for β2-MG corrleated with that for creatinine. Perioneal clearance for β2-MG was better in CAPD than in APD.

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