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이석권(Suk Kwon Lee),어완규(Wan Kyu Eo),최철준(Chul Joon Choi),조정휘(Chung Whee Choue),김권삼(Kwon Sam Kim),김명식(Myung Shick Kim),송정상(Jung Sang Song),배종화(Jong Hoa Bae) 대한내과학회 1990 대한내과학회지 Vol.39 No.2
N/A To access the hypothesis that left atrial enlargement as measured by echocardiography is the earliest sign of cardiac dysfunction in patients with systemic hypertension alone, we underwent M-mode echocardiography in 13 normal controls and 31 hypertensive patients who have neither quantitative evidence of left ventricular hypertrophy by noninvasive techniques, nor other causes of left atrial enlargement, such as coronary artery or valvular hart disease. The results were as follows: 1) There were no significant differences in left ventricular end-systolic and end-diastolic dimension, left ventricular mass, ejection fraction, or fractional shortening. 2) The left atrial dimension in the hypertensive patients (1.98±0.51cm) was significantly higher than normal control (3.27±0.46 cm) (p<0.05). 3) The left artial index was also higher in the hyper-tensive patients, 1.99±0.36cm/m² versus 2.42±0.39cm/m² (p<0.05), and the left atrial-to-aortic root dimension ratio was significantly higher in the hypertensive group, 1.10±0.14 versus 1.37±0.39 (p<0.05). The above results suggest that echocardiographic left atrial enlargement may be an early sign of hypertensive heart disease in patients with no other discernible causes of left atrial enlargement.