Dental management of patients with X-linked hypophosphatemia

이빈나,정혜윤,장훈상,황윤찬,황인남,오원만 대한치과보존학회 2017 Restorative Dentistry & Endodontics Vol.42 No.2

X-linked hypophosphatemia (XLH) is a hereditary metabolic disease caused by the loss of phosphate through the renal tubules into the urine, and an associated decrease in serum calcium and potassium phosphate. Its dental features include spontaneous dental abscesses that occur in the absence of trauma or dental caries. The aim of this case report was to describe the dental problems of XLH patients and to evaluate limitations in their treatment. A 14 year old male and a 38 year old female with XLH were referred to the Department of Conservative Dentistry for endodontic treatment. The dental findings were periapical abscesses without obvious trauma or caries. Conservative endodontic treatment was performed in teeth with pulp necrosis and abscess. In case 1, the treated teeth showed improvements in bone healing, without clinical symptoms. However, in case 2, the implants and the treated tooth showed hypermobility, and the final restoration was therefore postponed. Early diagnosis, periodic examinations, and communication with the patient's pediatrician are important in the dental management of patients with XLH.

A review of the regenerative endodontic treatment procedure

이빈나,문종욱,장훈상,황인남,오원만,황윤찬 대한치과보존학회 2015 Restorative Dentistry & Endodontics Vol.40 No.3

Traditionally, apexification has been used to treat immature permanent teeth that have lost pulp vitality. This technique promotes the formation of an apical barrier to close the open apex so that the filling materials can be confined to the root canal. Because tissue regeneration cannot be achieved with apexification, a new technique called regenerative endodontic treatment was presented recently to treat immature permanent teeth. Regenerative endodontic treatment is a treatment procedure designed to replace damaged pulp tissue with viable tissue which restores the normal function of the pulp-dentin structure. After regenerative endodontic treatment, continued root development and hard tissue deposition on the dentinal wall can occur under ideal circumstances. However, it is difficult to predict the result of regenerative endodontic treatment. Therefore, the purpose of this study was to summarize multiple factors effects on the result of regenerative endodontic treatment in order to achieve more predictable results. In this study, we investigated the features of regenerative endodontic treatment in comparison with those of other pulp treatment procedures and analyzed the factors that have an effect on regenerative endodontic treatment.

Comparison of TheraCal LC, Mineral trioxide aggregate, and Formocresolas pulpotomy agents in rat molar

이빈나,송영상,이고운,김영훈,장훈상,황윤찬,오원만,황인남 대한치과재료학회 2017 대한치과재료학회지 Vol.44 No.2

TheraCal LC, a new light-cured, resin-modified calcium silicate-filled base/liner material, has been introduced as a pulpotomy agent. The aim of this study was to evaluate the capacity of hard tissue formation and pulpal response after pulpotomy with TheraCal LC. Twenty-two 9-week-old male rats were anesthetized, cavities were prepared in maxillary first molars and pulps were capped with formocresol (FC), mineral trioxide aggregate (MTA), and TheraCal LC. Specimens obtained from rats were scanned using a high-resolution micro CT system. The specimens were prepared and evaluated histologically, and immunofluorescence assay was performed to assess the dentin matrix protein-1 (DMP-1) expression. On micro CT analysis, the MTA and TheraCal LC groups showed thicker hard tissue formation than the FC group. On hematoxylin and eosin (H&E) staining, MTA and TheraCal LC groups showed dentine bridge formation with vital pulp beneath the materials. On immunofluorescence analysis, DMP-1 was highly expressed in the TheraCal LC group compared to the FC group. TheraCal LC showed similar capacity to form hard tissue as MTA when it was used as a pulpotomyagent. Because of its good manipulation and faster setting time compared to MTA, TheraCal LC could be considered as a good alternative to MTA.

특성화 고등학교의 쇼윈도 디스플레이 디자인 교육 현황 연구

이빈나(Lee, Bin Na),김관배(Kim, Kwan Bae) 한국디지털디자인협의회 2014 (사)한국디지털디자인협의회 conference Vol.2014 No.5

Comparison of TheraCal LC, Mineral trioxide aggregate, and Formocresolas pulpotomy agents in rat molar

Bin-Na Lee(이빈나),Young-Sang Song(송영상),Go-Woon Lee(이고운),Young-Hoon Kim(김영훈),Hoon-Sang Chang(장훈상),Yun-Chan Hwang(황윤찬),Won-Mann Oh(오원만),In-Nam Hwang(황인남) 대한치과재료학회 2017 대한치과재료학회지 Vol.44 No.2

Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials

장영은,이빈나,고정태,박영준,주남억,장훈상,황인남,오원만,황윤찬 대한치과보존학회 2014 Restorative Dentistry & Endodontics Vol.39 No.2

Objectives: The aim of this study was to evaluate the cytotoxicity, setting time and compressive strength of MTA and two novel tricalcium silicate-based endodontic materials, Bioaggregate (BA) and Biodentine (BD). Materials and Methods: Cytotoxicity was evaluated by using a 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5- ((phenylamino)carbonyl)-2H-tetrazolium hydroxide (XTT) assay. Measurements of 9 heavy metals (arsenic, cadmium, chromium, copper, iron, lead, manganese, nickel, and zinc) were performed by inductively coupled plasma-mass spectrometry (ICP-MS) of leachates obtained by soaking the materials in distilled water. Setting time and compressive strength tests were performed following ISO requirements. Results: BA had comparable cell viability to MTA, whereas the cell viability of BD was significantly lower than that of MTA. The ICP-MS analysis revealed that BD released significantly higher amount of 5 heavy metals (arsenic, copper, iron, manganese, and zinc) than MTA and BA. The setting time of BD was significantly shorter than that of MTA and BA, and the compressive strength of BA was significantly lower than that of MTA and BD. Conclusions: BA and BD were biocompatible, and they did not show any cytotoxic effects on human periodontal ligament fibroblasts. BA showed comparable cytotoxicity to MTA but inferior physical properties. BD had somewhat higher cytotoxicity but superior physical properties than MTA.

브랜드 자산 모델을 통한 브랜드 경쟁력 지수 평가

全永鎬,李彬娜,林凞燮 弘益大學校 科學技術硏究所 2005 科學技術硏究論文集 Vol.16 No.-

Brand asset management to build powerful brand asset is needed to have more powerful comparative advantage. In this study, critical factors of the structure of brand asset are considered. For this purpose, the relationships between the brand asset and the structure of brand asset are evaluated. And measurement of the competitive power of the specific brand at the point of clients by describing the systematic measuring methodology of the brand asset and its applications is studied. And then, the model that can be used to solve and improve the general realities and level of brand management is proposed. For this, we recognized the strategic importance of brand asset and the brand asset management with previous studies. And we improved the model that showed that the increasing of brand competitive power makes purchasing intention and the brand loyalty increase at the point of clients by pointing out the limit of previous studies. With this improved model, we investigated the brand competitive power on digital electric home appliances about images, sounds, and communications. To test this model statistically, the structural equation model that is most popular in the latest is used. By using the result of this study, companies will be able to measure of their own and the other's brand competitive power and understand the method of benchmarking and the improvements. Moreover, the government will be able to draw up the plan and the system that support to secure the brand competitive power and bring up the global brand that have international competitive power.

Treatment of non-vital immature teeth with amoxicillin-containing triple antibiotic paste resulting in apexification

박현범,이빈나,황윤찬,황인남,오원만,장훈상 대한치과보존학회 2015 Restorative Dentistry & Endodontics Vol.40 No.4

A recent treatment option for non-vital immature teeth in young patients is revascularization with triple antibiotic paste (TAP). However, tooth discoloration was reported with the use of conventional minocycline-containing TAP. In this case report, amoxicillin-containing TAP was used for revascularization of non-vital immature teeth to prevent tooth discoloration. At the 1 yr follow up, the teeth were asymptomatic on clinical examination and showed slight discoloration of the crown due to mineral trioxide aggregate (MTA) filling rather than amoxicillin-containing TAP. Radiographic examination revealed complete resolution of the periapical radiolucency, and closed apex with obvious periodontal ligament space. However, the root growth was limited, and the treatment outcome was more like apexification rather than revascularization. These results may be due to unstable blood clot formation which could not resist the condensation force of MTA filling, whether or not a collagen matrix was in place. These cases showed that although revascularization was not successful, apexification could be expected, resulting in the resolution of the periapical radiolucency and the closure of the apex. Therefore, it is worthwhile attempting revascularization of non-vital immature teeth in young patients.

임시 가봉재가 상아질과 레진 인레이의 미세인장 결합 강도에 미치는 영향

김태우,이빈나,최영중,양소영,장훈상,황윤찬,황인남,오원만 大韓齒科保存學會 2011 Restorative Dentistry & Endodontics Vol.36 No.5

연구목적: 임상에서 주로 사용되는 가봉재가 레진 코팅된 상아질과 레진 인레이간 결합력에 미치는 영향을 밝히고, 지연 상아질 봉쇄법과 즉시 상아질 봉쇄법의 접착에 대한 효과를 비교 평가하고자 본 연구를 시행하였다. 연구 재료 및 방법: ZOE로 임시 가봉한 후 상아질 접착제로 지연 상아질 봉쇄법을 이용한 군을 1군, 즉시 상아질 봉쇄법을 이용하고 ZOE로 가봉한 군을 2군, 즉시 상아질 봉쇄법을 이용하고 Dycal로 가봉한 군을 3군, 즉시 상아질 봉쇄법을 이용하고 레진계열의 임시 가봉재로 가봉한 군을 4군으로 분류하였다. 각 그룹에서 가봉재를 제거하고 미리 제작한 레진 인레이를 와동에 합착한 후 근원심으로 절단하여 미세인장 결합 강도를 측정하였다. 결과: 1군에서 가장 낮은 결합력, 4군에서 가장 큰 결합력 나타내었다(p < 0.01). ZOE로 임시 가봉을 한 경우 즉시 상아질 봉쇄법이 지연 상아질 봉쇄법에 비해 결합력이 컸다(p < 0.01). 결론: 레진 인레이의 상아질 접착시 지연 상아질 봉쇄법보다 즉시 상아질 봉쇄법이 권고되며, 레진 계열의 임시 가봉재가 가장 우수한 결과를 보였다. Objectives: This study was aimed to determine the effects of temporary sealing materials on microtensile bond strength between resin-coated dentin and resin inlay and to compare the bonding effectiveness of delayed dentin sealing and that of immediate dentin sealing. Materials and Methods: The teeth were divided into 4 groups: group 1, specimens were prepared using delayed dentin sealing after temporary sealing with zinc oxide eugenol (ZOE); group 2, specimens were prepared using immediate dentin sealing and ZOE sealing; group 3, specimens were prepared using immediate dentin sealing and Dycal (Dentsply) sealing; group 4, specimens were prepared using immediately sealed, and then temporarily sealed with a resin-based temporary sealing material. After removing the temporary sealing material, we applied resin adhesive and light-cured. Then the resin inlays were applied and bonded to the cavity with a resin-based cement. The microtensile bond strength of the sectioned specimens were measured with a micro-tensile tester (Bisco Inc.). Significance between the specimen groups were tested by means of one-way ANOVA and multiple Duncan's test. Results: Group 1 showed the lowest bond strength, and group 4 showed the highest bond strength (p < 0.01). When temporary sealing was performed with ZOE, immediate dentin sealing showed a higher bonding strength than delayed dentin sealing (p < 0.01). Conclusions: Based on these results, immediate dentin sealing is more recommended than delayed dentin sealing in bonding a resin inlay to dentin. Also, resin-based temporary sealing materials have shown the best result.

Bonding efficacy of cured or uncured dentin adhesives in indirect resin

Ji-Hyun Jang,Bin-Na Lee,Hoon-Sang Chang,Yun-Chan Hwang,Won-Mann Oh,In-Nam Hwang 大韓齒科保存學會 2011 Restorative Dentistry & Endodontics Vol.36 No.6

Objectives: This study examined the effect of the uncured dentin adhesives on the bond interface between the resin inlay and dentin. Materials and Methods: Dentin surface was exposed in 24 extracted human molars and the teeth were assigned to indirect and direct resin restoration group. For indirect resin groups, exposed dentin surfaces were temporized with provisional resin. The provisional restoration was removed after 1 wk and the teeth were divided further into 4 groups which used dentin adhesives (OptiBond FL, Kerr; One-Step, Bisco) with or without light-curing, respectively (Group OB-C, OB-NC, OS-C and OS-NC). Pre-fabricated resin blocks were cemented on the entire surfaces with resin cement. For the direct resin restoration groups, the dentin surfaces were treated with dentin adhesives (Group OB-D and OS-D), followed by restoring composite resin. After 24 hr, the teeth were assigned to microtensile bond strength (μTBS) and confocal laser scanning microscopy (CLSM), respectively. Results: The indirect resin restoration groups showed a lower μTBS than the direct resin restoration groups. The μTBS values of the light cured dentin adhesive groups were higher than those of the uncured dentin adhesive groups (p < 0.05). CLSM analysis of the light cured dentin adhesive groups revealed definite and homogenous hybrid layers. However, the uncured dentin adhesive groups showed uncertain or even no hybrid layer. Conclusions: Light-curing of the dentin adhesive prior to the application of the cementing material in luting a resin inlay to dentin resulted in definite, homogenous hybrid layer formation, which may improve the bond strength. [J Kor Acad Cons Dent 2011;36(6):490-497.] 연구목적: 본 연구는 간접 레진수복시 상아질 접착제의 중합 여부가 레진인레이와 상아질간의 미세인장결합강도와 결합계면 의 형태에 미치는 영향을 공초점 현미경 관찰을 통하여 평가하고자 하였다. 연구 재료 및 방법: 24개의 발거된 대구치를 절단하여 교합면 상아질을 노출시켰다. 수복 방법에 따라 크게 간접 레진수복과 직접 레진수복의 두 군으로 나누었다. 간접 레진수복군은 임시 수복하여 1주일 후, 상아질 접착 과정에 따라 4군(OB-C와 OB-NC군, OS-C와 OS-NC군)으로 나누었다. 간접 레진수복군은 산부식 처리된 상아질면에 OptiBond FL (Kerr) 또는 One-Step (Bisco) 상아질 접착제를 중합 여부에 따라 나누어 적용하였다. 처리된 상아질면에 제작된 3 mm 높이의 레진 인 레이(Tescera, Bisco)를 Variolink II (Ivoclar Vivadent)를 사용하여 제조사의 지시에 따라 합착하였다. 직접 레진수복군은 산부식 처리된 상아질면에 상아질 접착 후, 복합레진 (EsteliteΣ, Tokuyama)으로 즉시 수복하였다(OB-D군, OS-D군). 수 복을 마친 모든 치아는 24시간 후, 미세인장 결합 강도 평가와 공초점 레이저 주사 현미경 관찰(CLSM)을 시행하였다. 결과: 간접 레진수복군은 직접 레진수복군에 비하여 낮은 미세인장결합강도를 나타내었으며, 상아질 접착제를 광중합한 군 (OB-C군, OS-C군)이 광중합을 시행하지 않은 군(OB-NC군, OS-NC군)에 비하여 높은 미세인장결합강도를 나타내었다. 접착 계면에 대한 CLSM 관찰에서 상아질 접착제를 광중합한 군에서 더 분명하고 균일한 혼성층이 관찰되었다. 상아질 접착 제를 광중합하지 않은 군에서는 혼성층이 불분명하거나 거의 관찰되지 않았다. 결론: 간접 레진수복물의 합착시 레진시멘트의 적용 전에 상아질 접착제의 광중합은 분명하고 균일한 혼성층의 형성하며, 이 는 결합강도의 향상에 기여한다.