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      • KCI등재

        양양 낙산사 원통보전 건칠관음보살상 연구

        이분희 한국불교미술사학회 2023 강좌미술사 Vol.61 No.-

        The Statue of Avalokitesvara Bodhisattva in Naksansa Temple had been enshrined in the main dharma hall of the temple ever since it was founded by the great Silla monk Uisang. However, the statue disappeared from the temple and was not retrieved until recently, when it was discovered at the nearby Yeonghyeolsa Temple, which is closely related with the worship of Avalokitesvara. As one of the dry-lacquered Buddhist statues produced between late Goryeo and early Joseon, the Statue of Avalokitesvara Bodhisattva in Naksansa Temple features a bejeweled headdress, lavishly decorated garments, elaborate finishing touches with a gold-painted interior, and the use of outstanding carving techniques. These aesthetic elements were much cherished by the royal family and nobility of both Goryeo and Joseon, suggesting that the statue was patronized by the royal family. The Statue of Avalokitesvara Bodhisattva is also marked by an imposing, proportional body sitting in the lotus position, suggesting that it was created as the principal Buddhist figure to be enshrined in Wontongjeon Hall. The Statue of Avalokitesvara Bodhisattva enshrined in Naksansa Temple is comparable in terms of it sculptural style with the gilt-bronze statue of Avalokitesvara and Ksitigarbhah enshrined in Daejeokgwangjeon Hall of Haeinsa Temple. The fact that the latter two were produced in 1351 suggests that the statue of Avalokitesvara might date back to the late fourteenth century. The elegant, well-defined face, well-built body with a voluminous chest, waist-band with a delightfully simple knot, and Ω-shaped fold in the robe on the left arm are all features that can be seen in statues of bodhisattvas dating back to the late Goryeo and early Joseon periods. Furthermore, the pedestal covered with the bodhisattva’s lower garment is a characteristic feature of the Buddhist statues made during late Goryeo under the influence of Buddhist sculpture of the Chinese Yuan dynasty.

      • KCI등재

        항정신병 약물에 의한 혈중 프로락틴 변화와 도파민 전달체 유전자 다형성

        이분희,김용구,서광윤,Lee, Bun-Hee,Kim, Yong-Ku,Suh, Kwang-Yoon 대한생물정신의학회 2003 생물정신의학 Vol.10 No.2

        Object:We investigated the relationship between prolactin response to antipsychotics and clinical courses of psychotic symptoms and DAT gene polymorphisms. Method:Twenty-four acute psychotic inpatients completed the 12-week trial of risperidone. Serum prolactin, BPRS, ESRS and hyperprolactinemia-related symptoms were measured at baseline, 2, 4, 8 and 12 weeks after medication. The DAT gene polymorphisms were analyzed. Results:The serum prolactin was significantly increased over time. According to the prolactin level at 2-week, the subjects were divided into the severe group(serum prolactin>60ng/mL, N=15) and the mild group (serum prolactin<60ng/mL, N=9). The prolactin levels of the mild group didn't increase beyond 60ng/mL throughout 12 weeks. Severe group had slower decrement of BPRS scores than those of mild group. Six females in severe group complained of irregular menstruations, but no female in mild group. Most patients had 10 allele of DAT gene. Conclusion:This study suggests that the magnitude of prolactin elevation at the 2-week of risperidone medication is correlated with severity of hyperprolactinemia throughout treatments. Our results did not show the relationship between prolactin responses and DAT gene polymorphisms.

      • KCI등재

        리스페리돈을 복용한 여성 환자에서 유발된 무월경의 치료

        이분희,김용구,한창수,고영훈,Lee, Bun-Hee,Kim, Yong-Ku,Han, Chang-Su,Ko, Young-Hoon 대한생물정신의학회 2003 생물정신의학 Vol.10 No.2

        Objective:To find out the optimal assessment that can relieve amenorrhea associated with risperidone. Methods:Sixteen female outpatients who have taken risperidone for more than 3 months reported voluntarily amenorrhea during Nov 2001 to May 2002. Since the reports of the amenorrhea, the resolution of amenorrhea has been prospectively followed during the next six months. The dosage of risperidone was reduced or discontinued in nine of sixteen patients, while risperidone was switched to olanzapine or quetiapine in other 7 patients according to the clinician's decision. Results:Fourteen of 16 patients showed higher levels of prolactin than normal level. Five patients of the risperidone-reduction group recovered from the amenorrhea while all subjects of the drug-switch group recovered. The resolved patients of the former group recovered from amenorrhea in the dosage below 3mg per day of risperidone. Two patients of the risperidone-reduction group were dropped out during the reduction. Conclusion:These findings suggest that risperidone-induced amenorrhea may be alleviated by reducing dosage to less 3mg per day(including discontinuation) or by switching to other antipsychotic drugs. Whether we would choose which method depends on patient's clinical status, diagnosis, and dose of medication and so on.

      • KCI등재후보

        산후우울증 환자에서 혈중 Nitric Oxide Metabolites의 혈장 농도의 변화

        이분희,김계현,신영철,김정범,김용구,Lee, Bun-Hee,Kim, Kye Hyun,Shin, Young Chul,Kim, Jung Bum,Kim, Yong-Ku 대한생물정신의학회 2006 생물정신의학 Vol.13 No.1

        Background : Some reports have suggested that decreased nitric oxide metabolites($NO_x$) and activity of nitric oxide synthase could be related to the pathophysiology of depression. We evaluated plasma levels of $NO_x$ in pregnant women with and without postpartum depression at prenatal and postnatal period. Methods : The plasma concentrations of $NO_x$ were measured in 104 pregnant women in the third trimester and at 6 weeks postpartum and in 64 normal controls. The severity of depression and anxiety was measured with the Edinburgh Postnatal Depression Scale(EPDS), Beck Depression Inventory(BDI), and Beck Anxiety Scale(BAI). Results : Plasma $NO_x$ levels at 6 weeks postpartum were significantly lower in cases of postpartum major depression(EDPS scores${\geq}$13 points) than in cases without depression(EDPS scores${\leq}$9 points). Plasma $NO_x$ levels had significantly negative correlation with EPDS scores at 6 weeks postpartum. Conclusion : We demonstrate that decreased plasma $NO_x$ is associated with postpartum depression. Further studies are required to determine whether individual serum concentration of plasma $NO_x$ alone could predict maternal depression.

      • KCI등재
      • KCI등재
      • KCI등재

        용문석굴 고양동과 골굴석굴의 비교연구

        이분희 한국불교미술사학회 2020 강좌미술사 Vol.54 No.-

        Longmen Caves are important cave temples in Chinese art history to understand cave temple construction and Buddha image style from the dynasty of BeiWei to the present days. They also had a great influence on Cave temples in Korea, and inscriptions of construction remain, providing abundant data. In this paper, we compared and explored Guyang Caves, the first cut among the Longmen Caves, and Golgul Caves, a Korean Cave temple. Longmen Guyang Caves have 19 out of 20 Longmen, and several inscriptions engraved therein also reveal the caves cutting, Buddha image construction, and construction faith at the time. Longmen Guyang Caves enshrines the Buddha image in the Shakyamuni Triad on the wall with the basic structure of a horseshoe, and a large number of tabernacles were created by dividing them into three floors on both walls and constructing large‐scale Buddha images. Buddha images show a Buddha image style that has more evolved into Chinese painting than Yungang Caves, and the Sakyamuni image and the Maitreya image were mainly enshrined. To examine the contents of the letter markings on the construction inscriptions as well as the iconographic specification, it can be seen that it was constructed based on Lotus Sutra thought. When comparing Golgul Caves and Longmen Guyang Caves, the cutting time of Longmen Guyang Caves is ahead of that of GolgulCaves, but it was the place visited by monks studying abroad since the Shilla era, and is believed to have influenced the cutting of Golgul Caves. The basic structure of both two caves is a horseshoe‐shaped U‐shaped plane, and at the entrance, there is a common thing that there used to be a wooden building. However, compared to Golgul Caves consisting of 10 monks common room caves in one worshiping cave, the difference is that Longmen Caves are difficult to distinguish between worshiping caves and monks common room caves. However, the construction thought of the two Caves is based on the Lotus Sutra thought, confirming that the Longmen Guyang Caves had a great influence on the Buddha image construction in Korea. 용문석굴은 중국미술사에서 북위시기부터 당대까지의 석굴사원의 조영과 불상양식을 이해하는데 중요한 석굴사원이다. 또한 우리나라의 석굴사원에도 그 영향을 많이 끼쳤으며, 조성기도 남아 있어 풍부한 자료를 제공한다. 본고에서는 특히 용문석굴 가운데 가장 먼저 개착되었으며, 규모도 큰 고양동 석굴과 우리나라 석굴사원인 골굴석굴을 비교하여 살펴보았다. 용문석굴 고양동은 용문 20품 가운데 19품이 있을 정도로 서예사적으로 중요한데, 그 안에 새겨진 여러 조상기를 통해 당시 석굴개착과 불상조성, 그리고 조성 신앙에 대해서 알 수 있다. 용문석굴 고양동은 말발굽형의 기본 구조이며, 정벽에 석가삼존의 불상을 봉안하고, 양 벽면에 3층으로 나누어 많은 감실을 만들고 대규모의 불상들을 조성하였다. 불상들은 운강 석굴보다 더욱 중국화로 진전된 불상양식을 보이며, 석가상과 미륵보살상이 주로 봉안되었다. 존명의 구분뿐만 아니라 조상기에 새겨진 명문의 내용을 파악해보면 법화경 사상을 근간으로 조성되었음을 알 수 있다. 골굴석굴과 용문석굴 고양동을 비교해보면, 용문석굴 고양동은 개착시기가 골굴석굴보다 앞서지만, 신라시대부터 구법승들이 자주 방문했던 곳으로, 골굴석굴 개착에 영향을 주었던 것으로 파악된다. 기본 구조은 두 석굴 모두 말발굽형의 U자형 평면이며, 입구에 목조 건축을 하였던 공통점이 있다. 그러나 골굴석굴이 하나의 예배굴에 10개의 승방굴로 구성되어 있는 것에 비해, 용문 석굴은 예배굴과 승방굴로 구분하기 어렵다는 차이가 있다. 그러나 두 석굴의 조영사상은 법화경 사상에 기반을 두어 용문석굴 고양동이 우리나라 불상 조성에도 큰 영향을 미쳤음을 확인할 수 있다.

      • KCI등재

        자살행동의 소인과 생물학적 인자의 관련

        이분희,김용구 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.3

        Suicide is a significant public health issue and a major cause of death throughout the world. There are significant evidences that the activity of 3 neurobiological systems has a role in the pathophysiology of suicidal behavior : a deficiency of serotonergic system, a hyperactivity of the hypothalamic-pituitary-adrenal axis, and an excessive release of noradrenalme. These neurobio-logical abnormalities might correlate with the diathesis of suicide including pessimism and aggression. Dysfunction of the Sero-tonergic system is thought to be associated with disturbances in the regulation of impulsivity and aggression, which may be trait-dependent factor. Hyperactivity of the hypothalamo-pituitary-adrenal axis and excessive activity of the noradrenergic system appear to be involved in the response to stressful events, which may be state-dependent factor, In the future, more understanding Se-veral aspect of suicidal behavior and the neurobiology of suicide can help detect promising predictors of suicidal behavior and treatment interventions.

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