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NANB 간질환 환자에서 2세대 효소 면역 검사법과 중합효소 연쇄 반응법을 이용한 C형 간염바이러스 감염의 진단
이복근(Bock Gyeon Lee),권기호(Ki Ho Kwon),박양훈(Yang Hun Park),김한성(Han Sung Kim),정찬수(Chan Su Jeong),제영성(Young Sung Jae),이준상(Joon Sang Lee),유방현(Bang Hyun Liu),박영홍(Young Hong Park),이기영(Kee Young Lee) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.5
N/A The first-generation enzyme linked imrnumosorbent assay(ELISA) method to detect hepati- tis C virus(HCV) has been used with relatively good sensitivity in the diagnosis of chronic non A non B hepatitis infecton, but its sensitivity in cases of acute hepatitis remains poor. The secondeneration ELISA which uses recombinant proteins and synthetic peptides from both structural and nonstructural regions increases the sensitivity in diagnosing HCV infection, and diminishes the number of false-positive reactions. The polymerase chain reaction(PCR) has been used to detect infectivity of anti HCV positive patients more accurately, to evaluate ver- tical transmission, and to monitor the response to antiviral ther~apy for chronic HCV infection. Serum samples from 35 patients with non A non B type liver disease were tested by the secondeneration ELISA and the PCR to evaluate the roles of hepatitis C viral infections in NANB patients. HCV RNA was detected by single polymerase c~t~ain reaction technique using primers deduced from the 5noncoding region of HCV genome. Among the 35 patients, 27 pa- tients were positive for anti HCV (Group A), while 8 were negative for anti HCV(Group B). Among anti HCV positive patients, 11% and 33% o~f patients were related to the transfu- sion and acupuncture, respectively. We could detect HCV RNA in the sera from 27 patients (100%) in the group A and 4 patients(50%) in the group B. We conclude that the combination methods of secondeneration ELISA plus PCR reduce the chance of false diagnosis of HCV infection compared to the first generation ELISA and the PCR can be used to diagnose HCV infection in anti HCV negative hepatitis patients.(Ko- rean J Gastroenterol 1994; 26; 825 832)
담배광고 목격경험과 담배회사의 사회공헌활동에 대한 선호도가 청소년의 현재 흡연과 미래 흡연의도에 미치는 영향
신성례,신선화,이복근,양진희 한국지역사회간호학회 2014 지역사회간호학회지 Vol.25 No.1
Purpose: To evaluate the influence of experiences of witnessing tobacco advertising and preferences of tobaccocompanies' social responsibility (CSR) on current and future smoking intentions in adolescents. Methods: Datawere collected from 700 adolescents living in Korea representing 7 metropolitan cities and 8 provinces in the methodof proportional random sampling. The Gallup's data collection system was adopted using 1:1 face to faceinterviews. The witness of tobacco advertising was determined by 'yes', or 'no' responses to three survey itemsand to four survey items for preferences of tobacco CSR. For statistical analysis, x2 test, Fisher's exact test andlogistic regression were used. Results: 98.4% of the adolescents had experiences of witnessing tobaccoadvertising. POP (OR=103.44, 95% CI: 8.22~1301.45) and magazine advertisement (OR=6.07, 95% CI: 1.34~22.58) had a significant effect on their current smoking. Also, POP (β=.24, p<.001) and movie advertisement (β=.42, p<.001) had a significant effect on their future smoking intentions. As for the preferences of tobacco CSR,cultural-art support activities (β=.15, p=.025) and environmental purifying campaigns (β=-.15, p=.034) had a significanteffect on their future smoking intentions. Conclusion: Witness of tobacco advertising and positive responsesto tobacco CSR are associated with current and future smoking intentions in adolescents.
청소년들의 담배광고 목격경험과 흡연수용도가 성인기 흡연의도에 미치는 영향
신성례,정구철,이복근 한국청소년학회 2012 청소년학연구 Vol.19 No.10
The purpose of this study was to investigate the influence of cigarette advertising and susceptibility to smoking on future smoking intention. The data was collected from 995 adolescents aged between 12 and 18 living in Seoul and ChungNam area. Their socio-demographic characteristics, present smoking status, future smoking plan, exposure and frequency of advertising, and receptivity to tobacco advertising were collected. Chi-square tests and logistic regression analysis were carried out using SPSS version 19.0. The participants who were exposed to the cigarette advertisement (Odds Ratio(OR) 1.10; 95% Confidence Interval(CI) 1.05-1.15); who had higher receptivity score(OR=1.17; 95% CI=1.05-1.31) were favorable to future smoking. We concluded that the cigarette advertising increases the smoking receptivity and adulthood smoking plan among adolescents. 본 연구는 청소년들의 담배광고 목격 경험과 흡연수용도가 추후 성인기 흡연의도에 미치는 영향을 분석하기 위해 수행되었다. 연구대상은 중․고등학교 학생 995명이었으며, 수집된 자료는 SPSS(ver. 19.0)을 이용하여 χ2-test, ANOVA, 다중 회귀분석과 로지스틱 및 다항로지스틱 회귀분석을 통해 검정하였다. 분석결과 청소년들의 담배광고 목격경험은 흡연수용도에 유의한 정적 영향을 미쳤으며, 담배광고 목격 경험과 흡연수용도 모두 현재의 흡연상태에 유의한 정적 영향을 미쳤다. 평생 금연집단을 기준으로 하여 담배광고 목격 경험이 증가할수록 미결정 집단을 예측할 승산비(OR)는 1.10배, 흡연수용도가 증가할수록 성인기 흡연의도 집단을 예측할 승산비는 1.15배 증가하는 것으로 나타났다. 또한 미결정 집단을 기준으로 흡연수용도가 증가할수록 성인기 흡연의도 집단을 예측할 승산비는 1.17배로 분석되었다. 결론적으로 담배광고는 흡연수용도와 흡연할 확률을 높이고, 궁극적으로 성인기 흡연의도를 향상시키는 원인이 되므로 직․간접적인 모든 담배광고 금지에 관한 법률 제정과 같은 강력한 정책적 대안이 모색되어야 함을 논의하였다.
김창용(Chang-Yong Kim),이복근(Bock-Gyun Lee),배재학(Jae-Hak J. Bae) 한국정보과학회 2001 한국정보과학회 학술발표논문집 Vol.28 No.2Ⅱ
본 논문에서는 초 · 중등학교 종합정보관리시스템을 국가인적자원관리시스템으로 활용할 수 있다고 보고 전 국민의 건강정보관리에 이용할 방안을 모색하였다. 이를 위해 종합정보관리시스템의 학생건강기록부와 의사가 기록하는 전자의무기록부의 통합DB화를 강구하였다. 그 결과, 학교와 병원에서 공통으로 관리해야 할 건강정보들을 파악하였고, 수요자에게는 어떤 정보를 제공하여야 하는지가 밝혀졌다.