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이명철,조현철,김태균,성인호,성상철,Lee, Myung Chul,Jo, Hyun Chul,Kim, Tae Gyun,Seong, In Ho,Seong, Sang Cheol 대한관절경학회 1998 대한관절경학회지 Vol.2 No.2
Spontaneous osteonecrosis of the knee was first described by Ahlbck et al in 1968 as the spontaneous and sudden onset of severe pain, usually on the medial side of the knee joint, in old age(>60 years) with no specific etiologic factors. They differentiate the disease from osteochondritis dissecans, osteoarthritis, fracture, infection, neuropathic joint and secondary osteonecrosis of the knee joint. So far many investigators described this disease but had never observed cases developed in young patient with familial occurrence. The report presented here is a case of spontaneous osteonecrosis of both medial and lateral femoral condyles involving the bilateral knee joint that were treated by arthorscopic loose body removal and multiple drilling.
이명철(Myung Chul Lee),이경한(Kyung Han Lee),윤병우(Byung Woo Yoon),이원용(Won Yong Lee),이기형(Ki Hyeong Lee),이상복(Sang Bok Lee),전범석(Beom S . Jeon) 대한핵의학회 1996 핵의학 분자영상 Vol.30 No.1
N/A Progressive supranuclear palsy (PSP) is a parkinson-plus syndrome characterized clinically by supranuclear ophthalmoplegia, pseudobulbar palsy, axial rigidity, bradykinesia, postural instability and dementia. Presence of dementia and lack of cortical histopathology suggest the derangement of cortical function by pathological changes in subcortical structures in PSP, which is supported by the pattern of behavioral changes and measurement of brain metabolism using positron emission tomography. This study was done to examine whether there are specific changes of regional cerebral perfusion in PSP and whether there is a correlation between severity of motor abnorma- ility and degree of changes in cerebral perfusion. We measured regional cerebral perfusion indices in 5 cortical and 2 subcortical areas in 6 patients with a clinical diagnosis of PSP and 6 healthy age and sex matched controls using Tc-99m-HMPAO SPECT. Compared with age and sex matched controls, only superior frontal regional perfusion index was significantly decreased in PSP (p〈0.05). There was no correlation between the severity of the motor abnormility and any of the regional cerebral perfusion indices (p〉0.05). We affirm the previous reports that perfusion in superior frontal cortex is decreased in PSP. Based on our results that there was no correlation between severity of motor abnormaility and cerebral perfusion in the superior frontal cortex, nonmotoric symptoms including dementia needs to be looked at whether there is a correlation with the perfusion abnormility in superior frontal cortex.
휴식기 T1-201/디피리다몰 부하 게이트 Tc-99m-MIBI/24시간 지연 T1-201 SPECT 를 이용한 관상동맥 우회로 수술 후 심근벽 운동 호전의 예측
이명철(Myung Chul Lee),정준기(June Key Chung),이동수(Dong Soo Lee),이원우(Won Woo Lee),김기봉(Ki Bong Kim),여정석(Jeong Seok Yeo),김석기(Seok Ki Kim) 대한핵의학회 1998 핵의학 분자영상 Vol.32 No.6
N/A Purpose: Using rest T1-201/dipyridamole stress Tc-99m-MIBI/24 hour T1-201 SPECT, we investigated the predictive values of the markers of the stress-rest reversibility (Rev), T1-201 rest perfusion (Rest), T1-201 24 hour redistribution (Del) and Tc-99m-MIBI gated systolic thickening (Thk) for wall motion improvement after coronary artery bypass surgery. Materials and Methods: In 39 patients (M:F=34:5, age 58±8), preoperative and postoperative (3 months) SPECT were compared. 24 hour delayed SPECT was done in 16 patients having perfusion defects at rest. Perfusion or wall motion was scored from 0 to 3 (0:normal to 3:defect or dyskinesia). Wall motion was abnormal in 142 segments among 585 segments of 99 artery territories which were surgically revascularized. Results: After bypass surgery, ejection fraction increased from 37.8±9.0% to 45.5±12.3% in 22 patients who had decreased ejection fraction preoperatively. Wall motion improved in 103 (72.5%) segments among 142 dysfunctional segments. Positive predictive values (PPV) of Rev, Rest, Del, and Thk were 83%, 76%, 43%, and 69% respectively. Negative predictive values (NPV) of Rev, Rest, Del, and Thk were 48%, 44%, 58%, and 21%, respectively. Rest/gated stress/delay SPECT had PPV of 74% and NPV of 46%. Though univariate logistic regression analysis revealed Rev (p=0.0008) and Rest (p=0.024) as significant predictors, stepwise multivariate test found Rev as the only good predictor (p=0.0008). Conclusion: Among independent predictors obtained by rest T1-201/stress gated Tc-99m-MIBI/delayed T1-201 myocardial SPECT for wall motion improvement after bypass surgery, stress-rest reversibility was the single most useful predictor.
골절부위에 생긴 혈종의 골막하 이식이 골형성에 미치는 영향에 관한 실험적 연구 - 골스캔 소견을 중심으로 -
이명철(Myung Chul Lee),양승오(Seoung Oh Yang),강흥식(Hung Sik Kang),장기현(Kee Hyun Chang),구경회(Kyung Hoi Koo),성상철(Sang Chul Seung),박인애(In Ae Park) 대한핵의학회 1990 핵의학 분자영상 Vol.24 No.1
N/A It has been reported that hematoma is one of the most crucial factors in fracture healing since callus formation is disturbed by washing out the hematoma near a fracture site. However, it is not clear why the hamatoma is important and how it plays a role during the fracture healing. In order to investigate the role of hematoma in the process of fracture healing, the osteogenic potential by subperiosteal transplantation have been studied. Experimental fractures by operation were made at the mid-shaft of the tibia in New Zealand white rabbits. Removal of hematoma at the fracture site was done after 2 and 3 days from experimental fracture, and the removed hematoma was transplanted into the subperiosteal area at the mid-shaft of the ulna of each rabbit. As control gorups, we have performed 3 different procedures 1) the hematoma was transplanted into the muscular layers at the thigh and forearm; 2) autologous blood clots were transplanted into the subperiosteal area of the ulna; and 3) sham operation without a transplantation into the subperiosteal area. After transplantation, seria bone scintigraphy and simple radiography were performed at 4 days, 1 week, and 2 weeks to detect an abnormality. The results of bone scintigraphy were positive in 5 of 6 experimental group. However, a11 in three control groups were negative. Histological observation of the positive bone revealed new bone formation with trabeculation. These results suggest the hematoma in fracture site has osteogenic potential in the subperiosteal area which can be demonstrable by bone scintigraphy and histologic findings. Therefore, it is considered that hematoma of the fracture site plays an important role in the process of fracture healing. Further biochemical investigation using various experimentaI models is mandatory to apply this preliminary result to the treatment of clinical delayed union or nonunion.
이명철 ( Myung-chul Lee ),한수현 ( Soo-hyun Han ),이재성 ( Jae Sung Lee ) 한국정보처리학회 2019 한국정보처리학회 학술대회논문집 Vol.26 No.2
기업이나 정부 등의 정책 결정에 활용하기 위해, SNS에서 사용하는 키워드를 추출하여 소비자나 유권자의 관심과 선호도를 분석하는 방법이 많이 사용되고 있다. 본 논문에서는 다수의 SNS 사이트에 올린 글과 그에 대한 공감(좋아요) 댓글, 해시태그를 분석하여 관심 키워드의 트렌드를 분석할 수 있는 시스템을 제안한다. 이 시스템에서는 각각의 SNS 글을 형태소 분석하여 키워드 빈도를 측정하고 그에 대한 공감 및 해시태그의 갯수를 계산하여 일정기간 동안의 변화를 그래프로 표시하였다. 이를 통해, 여러 사이트에서의 키워드 트렌드를 한눈에 확인할 수 있도록 했다.
IEC 61508 기준 PES 기반 전자연동장치의 기능 안전도 분석에 관한 연구
이명철(Myung-Chul Lee) 대한전기학회 2014 전기학회논문지 Vol.63 No.11
The Electronic Interlocking unit in railway signalling system is safety-related facilities to determine route and speed for train running. In particular, the SSI(Solid State Interlocking) is Electronic Interlocking unit for high-speed railway, and it performs safety-critical function by MPM(Micro-Processor Module). Meanwhile, MPM is composed of the PES(Programmable Electronic System)-based system, and the PES-based system in railway safety-related facilities should be implemented by complying with the safety requirements defined in IEC 62425 and IEC 61508. In this paper, we performed modeling of failure rate and reliability for MPM implemented by fault tolerance methods and analyzed functional safety for MPM. Moreover, we determined SIL(Safety Integrity Level) for MPM according to the safety requirements defined in IEC 61508 based on an analyzed functional safety.