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피부에 발생한 Smooth Muscle Tumor of Uncertain Malignant Potential
이두락 ( Doo Rak Lee ),최연진 ( Yeon Jin Choi ),안지영 ( Ji Young Ahn ),박미연 ( Mi Youn Park ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.5
Smooth muscle tumors have been classified into leiomyoma and leiomyosarcoma. But the criteria for malignancy are not well defined. Traditionally, mitoses are the most important differentiating feature between leiomyoma and leiomyosarcoma. However mitotic activity was regarded as an acceptable finding in about 20% of cutaneous leiomyoma. The widely used designation “smooth muscle tumor of uncertain malignant potential” is a reflection of the limitation of available criteria to precisely diagnose tumors with borderline atypical features. We present herein a case of a cutaneous smooth muscle tumor of uncertain malignant potential, which is mitotically active, on the abdomen of a 45-year-old man. (Korean J Dermatol 2008;46(5):678∼681)
이두락 ( Doo Rak Lee ),신미선 ( Mi Seon Shin ),박미연 ( Mi Youn Park ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.7
Eosinophilic cellulitis is a rare recurrent inflammatory dermatosis, characterized clinically by well-circumscribed erythematous plaques. The histopathologic features of the lesions are dermal edema, infiltration of eosinophils and development of `flame figures` in the dermis. A 64-year-old female presented pruritic erythematous plaques, with associated bullae, on her right hand and wrist. Histopathologic examination showed infiltration of eosinophils and characteristic flame figures in the dermis. The clinical presentation and histopathologic alterations are consistent with the diagnosis of eosinophilic cellulitis. Herein, we report a case of bullous eosinophilic cellulitis which is an uncommon variant of eosinophilc cellulitis. (Korean J Dermatol 2008;46(7):945~949)
Indocyanine Green과 805 nm Diode Laser를 이용한 여드름 치료에 대한 유효성 평가
이두락 ( Doo Rak Lee ),박미연 ( Mi Youn Park ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.9
Background: Acne vulgaris is one of the most common dermatologic diseases and the main method of treatment is antibiotics and retinoids. However, many patients experience a need for a different treatment because of the transient effect and severe adverse effects. The study reported herein evaluated the effect and safety on acne vulgaris of 805 nm diode laser and topical Indocyanine green (ICG). Objective: To demonstrate the efficacy of the near-infrared diode laser phototherapy in combination with topical application of ICG in the treatment of acne vulgaris. Methods: Twenty-three volunteers with varying degrees of acne were enrolled in the study. Half of the face was stained by ICG. After 15 minutes, the whole face was irradiated by 805 nm diode laser. The procedure was carried out two times a week for 4 weeks. Inflammatory, non-inflammatory acne lesions were counted and sebum levels of both cheeks were measured. Results: The mean reduction of the inflammatory lesion counts was 43% in the ICG-diode laser group. The mean clearance of non-inflammatory lesions was 25% in the ICG-diode laser group. Significant reduction of acne lesions were observed in ICG-diode laser group compared to diode laser group (p<0.05). The adverse effects were negligible on both sides of the face. Conclusion: ICG and diode laser therapy is effective in the treatment of moderate to severe acne vulgaris, and none of significant adverse effects were observed. (Korean J Dermatol 2008;46(9):1208~1215)