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마우스에 있어서 Diethylstilbestrol의 免疫毒性에 미치는 紅蔘 Ethanol 抽出物의 影響
이덕행,안영근 원광대학교 식품약품안전성연구소 1991 食品藥品安全性硏究 Vol.4 No.-
The effect of red ginseng ethanol extract on the inninotoxicity of diethylstilbestrol (DES) was studied in ICR mice. ICR male mice were divided into 5 groups (10mice/group), and red ginseng ethanol extract(50, 100 and 200 ㎎/㎏ body wt., respectively) and DES (1㎎/㎏ boky wt.) were injected intraperitoneally (i.p.) to ECR mice once a day for 2 weeks. Mice wre sentitized and challenged with sheep red blood cells(S-RBC). Immune response were evaluated by humoral immunity, cell-meiated immunity, non-specific immunity, and circulating leukocyte counts. The results of this study were summarized as followings: 1. The DES-treated control group as compared with normal group showed the tendency to decrease body weight rate and relative liver weight, decreased both humoral and cellular immune responses, phagocyte activity, and circulating leudocyte counts, but increased the natural killer (NK) cell activity. 2. Compared with the DES-treated control group, DES plus red ginseng ethanol extract-treated groups significantly decreased the body weight rate(P<0.01). Rclative liver weight was significantly decreased in DES plus RED ginseng ethanol extract (50㎎/㎏)-treated group (P<0.01), but significantly increased in DES plus red ginseng ethanol extract (100㎎/㎏)-treated group (P<0.01). Relative spleen and thymus weights were significantly enhanced in DES plus red ginseng ethanol extract (100㎎/㎏)-treated group(P<0.01), but significantly decreased in DES plus red ginseng ethanol extract (200㎎/㎏)-treated group(P<0.01) 3. Both humoral and cellular immune responses were significantly decreased in DES plus red ginseng ethanol extract-treated groups rather than in the DES-treated control group(P<0.01). Especially, it weakened the decrease in DES plus red ginseng ethanlo extract (100㎎/㎏)-treated group. 4. Phagocyte activity and circulating leudocyte counts were significantly decreased in DES plus red ginseng ethanol extract-treated groups rather than in the DES-treated control group (P<0.01). Especially, it weakened the decrease in DES plus red ginseng ethanol extract (100㎎/㎏)-treated group (P<0.01), but significantly decreased in DES plus red ginseng ethanol extract (50 and 200 ㎎/㎏)-treated groups (P<0.01).
마우스에 있어서 Diethylstilbestrol의 免疫毒性에 미치는 紅蔘 Ethanol 抽出物의 影響
이덕행,안영근 한국환경독성학회 1991 환경독성보건학회지 Vol.6 No.1
The effect of red ginseng ethanol extract on the immunotoxicity of diethylstilbestrol (DES) was studied in ICR mice. ICR male mice were divided into 5 groups (10 mice/group), and red ginseng ethanol extract (50, 100 and 200 mg/kg body wt., respectively) and DES (1 mg/kg body wt.) were injected intraperitoneally (i.p.) to ICR mice once a day for 2 weeks. Mice were sensitized and challenged with sheep red blood cells (S-RBC). Immune response were evaluated by humoral immunity, cell-mediated immunity, non-specific immunity, and circulating leukocyte counts. The results of this study were summarized as followings: 1. The DES-treated control group as compared with normal group showed the tendency to decrease body weight rate and relative liver weight, decreased both humoral and cellular immune responses, phagocyte activity, and circulating leukocyte counts, but increased the natural killer (NK) cell activity. 2. Compared with the DES-treated control group, DES plus red ginseng ethanol extract-treated groups significantly decreased the body weight rate (P<0.01). Relative liver weight was significantly decreased in DES plus red ginseng ethanol extract (50 mg/kg)-treated group (P<0.01), but significantly increased in DES plus red ginseng ethanol extract (100 mg/kg)-treated group (P<0.01). Relative spleen and thymus weights were significantly enhanced in DES plus red ginseng ethanol extract (100 mg/ kg)-treated group (P<0.01), but significantly decreased in DES plus red ginseng ethanol extract (200 mg/kg)-treated group (P<0.01). 3. Both humoral and cellular immune responses were significantly decreased in DES plus red ginseng ethanol extract-treated groups rather than in the DES-treated control group (11<0.01). Especially, it weakened the decrease in DES plus red ginseng ethanol extract (100 mg/kg)-treated group. 4. Phagocyte activity and circulating leukocyte counts were significantly decreased in DES plus red ginseng ethanol extract-treated groups rather than in the DES-treated control group (P<0.01). Especially, it weakened the decrease in DES plus red ginseng ethanol extract (100 mg/kg)-treated group. NK cell activity was significantly enhanced in DES plus red ginseng ethanol extract (100 mg/kg)-treated group (P<0.01), but significantly decreased in DES plus red ginseng ethanol extract (50 and 200 mg/kg)-treated groups (P<0.01).
Thermal Analysis of MIRIS Space Observation Camera for Verification of Passive Cooling
이덕행,한원용,문봉곤,박영식,정웅섭,박귀종,이대희,표정현,김일중,mingyukim,toshiomatsumoto 한국우주과학회 2012 Journal of Astronomy and Space Sciences Vol.29 No.3
We conducted thermal analyses and cooling tests of the space observation camera (SOC) of the multi-purpose infrared imaging system (MIRIS) to verify passive cooling. The thermal analyses were conducted with NX 7.0 TMG for two cases of attitude of the MIRIS: for the worst hot case and normal case. Through the thermal analyses of the flight model, it was found that even in the worst case the telescope could be cooled to less than 206°K. This is similar to the results of the passive cooling test (~200.2°K). For the normal attitude case of the analysis, on the other hand, the SOC telescope was cooled to about 160°K in 10 days. Based on the results of these analyses and the test, it was determined that the telescope of the MIRIS SOC could be successfully cooled to below 200°K with passive cooling. The SOC is, therefore, expected to have optimal performance under cooled conditions in orbit.
이덕행,문봉곤,박영식,이대희,정웅섭,이창희,남욱원,박성준,표정현,차상목,가능현,박장현,선광일,이승우,박종오,이형목,Matsumoto, Toshio,한원용 한국우주과학회 2011 한국우주과학회보 Vol.20 No.1
System(MIRIS)는 한국천문연구원이 개발하고 있는 소형 적외선 우주망원경이다. MIRIS는 적외선 센서의 열잡음을 최소화시키기 위하여 망원경의 온도가 허용범위를 넘지 않도록 설계되었다. 특히 3K의 심우주를 향해 MIRIS의 복사열을 자연 방출하는 Passive cooling은 임무 성공에 영향을 미치는 매우 중요한 과정이다. 이를 검증하고자 NX 7.0(Space Systems Thermal, TMG 탑재)을 사용하여 열 해석을 수행하였다. 각 부품별로 물성과 열광학 특성을 적용하여 전도 및 복사를 통한 열전달 과정을 계산하였고, MIRIS의 궤도 특성을 고려하여 정상상태에서의 망원경 온도를 얻었다. 그 결과 Passive cooling을 통해 MIRIS 망원경이 허용범위 아래로 냉각되는 것을 확인하였다.
Best Effort 환경에 적절한 멀티미디어 데이터 전송 알고리즘 설계
허덕행(Duck-haing Huh) 한국컴퓨터정보학회 1999 韓國컴퓨터情報學會論文誌 Vol.4 No.4
화상회의 응용이 인터넷을 통해 최선의 서비스를 제공하려면 실 시간성을 지원해야 하는데, 인터넷의 동적인 특성상 멀티미디어 응용의 서비스 품질을 보장하지 못한다. 이런 이유로 화상회의 용용은 송신자와 수신자 사이의 현재 사용 가능한 대역폭을 측정하여 데이터를 적절하게 전송하는 것이 필요하다.<br/> 본 논문은 RTCP(Real-time Transport Control Protocol)를 사용하여 가용 대역폭을 측정하고, 측정된 가용 대역폭을 토대로 멀티미디어 데이터를 적절하게 전송하기 위해 코덱에서의 데이터 생성량을 줄이고, 데이터 압축률을 변화시키고, 전송 버퍼에서 패킷 손실률을 기반으로 패킷의 우선 순위에 따라 프레임을 폐기하여, 대역폭에 유연하게 실시간 멀티미디어 데이터를 전송하는 알고리즘을 제안한다. Various applications of video conferencing are required real-time transmission in order to offer service of best effort in internet. Because the bandwidth of internet changes dynamically, appropriated QoS could not be guaranteed. To resolve the problem, available bandwidth between sender and receiver is measured. And according to measured bandwidth, the transmission of multimedia data is controlled.<br/> In this paper, we propose algorithm of efficient transmission for best QoS in internet. According to a present status of network, we measure available bandwidth using feedback RTCP information and change a compression rate to reduce a producing CODEC data. And according to the priority that is measured by packet loss for received RTCP information, we abandon frames indicated as lower weight in transmission buffer of sender.
이덕행(Duk Heng Lee),이용주(Yong Joo Lee) 한국생약학회 1979 생약학회지 Vol.10 No.1
A trace amount of nicotine, main constituent in tobacco, contaminated in coffee, was identified by the T.L.C method. The Eastman chromagram plate was used and determined with the linear scanning by transmission method. It was possible to identify nicotine in coffee beverage regardless of types of tobacco. Ten micrograms of nicotine could be determined in a cup of coffee (75㎖), which was acidified with hydrochloric acid.