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이금신(Keum Sin Lee),김훈영(Hun Young Kim),김병륜(Byung Ryun Kim),이봉주(Bong Ju Lee),김흥곤(Heung Gon Kim) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.5
Actinomycosis is a rare cause of indolent pelvic infection secondary to the seeding of upper genital tract from other intraabdominal or hematogenous dissemination of actinomyces. In addition, ascending pelvic actinomycotic infection has been described in patients with IUD. Pelvic actinomycosis has variable clinical manifestations, which make it diffcult to diagnose preoperatively. Colonization of lower genital tract by Actinomyces occurs most often in IUD users and increases with the duration of IUD use. We have experienced two cases of actinomycosis in IUD users and report them with a review of literatures.
은명숙,이금신,이영희,이지애,이형미 曉星女子大學校 藥學大學 學生會 1986 曉星藥誌 Vol.3 No.-
Vitreous concentration of sodium, potassium, magnesium, calcium and chloride were studied after extracapsular lens extraction and surgery equivalent to intracapsular lens extraction on rabbit eye. Both surgery did not affect on the concentration of sodium, potassium, calcium and magnesium in the vitreous. But chloride concentration in vit-reous by chloride shift to balance osmotic pressure of vitreous gel.
오수미(Su Mi Oh),이금신(Keum Sin Lee),심재량(Jae Ryang Sim),고경희(Kyoung Hee Ko),이봉주(Bong Ju Lee),김흥곤(Heung Gon Kim),문형배(Hyung Bae Moon) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.5
The association of carcinoma and tuberculosis in any organ is rare and in the endometrium is extremely rare. Only a small number of cases of endometrial tuberculosis with coexisting endometrial adenocarcinoma have been reported in the literature. We experienced a case of endometrial tuberculosis with coexisting endometrial adenocarcinoma and report with a brief review of literature.
In situ PCR과 Hybrid Capture System을 이용한 자궁경부종양에서 인유두종 바이러스의 검출
김흥곤,문형배,이봉주,신형도,홍성진,이금신,곽효일 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.7
목적: 자궁경부염, 자궁경부 상피내종양, 침윤암으로 진단된 검체를 대상으로 in situ PCR과 Hybrid capture system을 이용하여 두 검사 방법사이의 HPV검출률을 비교 분석하고자 한다. 연구방법: 1996년 8월부터 1998년 3월까지 본원에서 자궁경부염, 자궁경부 상피내종양, 침윤암으로 진단된 70명의 환자를 대상으로 in situ PCR과 Hybrid capture system을 이용하여 HPV검출을 실시 하였다. 결과 : 1. Hybrid capture system을 이용한 경우 만성 자궁경부염 33.3%, CIN I 35.8%, CIN II 53.9%, CIN III 60.0% , 그리고 침윤성 자궁경부암 70.3% 에서 HPV DNA 검출률을 보였다. 2. In situ PCR을 이용한 경우 만성 자궁경부염 40.0%, CIN I 42.8%, CIN II 77.0%, CIN III 86.7%, 침윤성 자궁경부암 84.6%에서 HPV DNA 검출률을 보였다. 결론: 본 연구에서 in situ PCR을 이용 할 경우[67.5%] 자궁경부에서 HPV의 감염여부를 검출함에 있어서 Hybrid capture system 검사법[50.0%] 보다 더 예민하고 정확한 검사법으로[p$lt;0.005] 사료된다. Objective: To determine the prevalence of HPV infection in chronic cervicitis, cervical intraepithelial neoplasia [CIN] I, II, III and invasive cervical cancer using the in situ PCR and Hybrid capture system. Methods: We studied on 70 patients who had undergone conization for cervical lesion with chronic cervicitis, CIN, invasive cervical carcinoma at our hospital between August 1996 and March 1998. We compared the efficacy of Hybrid CaptureTM [Digene, USA] system and in situ PCR for HPV DNA detection according to disease entity. Results: Using the Hybrid capture system, the detection rates of HPV showed 33.3% in chronic cervicitis, 35.8% in CIN I, 53.9% in CIN II, 60.0% in CIN III and 70.3% in invasive cervical cancer. On the other hand the detection rates of HPV by in situ PCR system showed 40.0% in chronic cervicitis, 42.8% in CIN I, 77.0% in CIN II, 86.7% in CIN III and 84.6% in invasive cervical cancer. Conclusion: This study demonstrated that the detection rate of HPV using the in situ PCR [65.7%] is more sensitive and accurate than Hybrid capture system [50.0%].[p$lt;0.005].