탈지분유 함유 식이를 섭취하는 흰쥐에서 칼슘과 비타민 D 수준이 무기질 대사에 미치는 영향

이경민,이연주,원은숙,이상선,Lee, Kyung-Min,Lee, Yeon Joo,Won, Eun-Sook,Lee, Sang Sun 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.4

The purpose of this study was to investigate the effect of calcium (Ca) and vitamin D (vit. D) levels on metabolism of various minerals such as Ca, P, Mg, Fe, Zn, Cu, and Cr. The comparison was made on the rats that were placed on diet containing powdered skim milk with different Ca and vit. D levels for 5 weeks. A total of 42 5-week-old Sprague-Dawley rats were divided into 7 groups as follows: Control group consisted of normal Ca and normal vit. D (0.5% Ca, 1,000 IU vit. D); Experimental groups were divided into low (0.25%) and high (1.0%) calcium levels; and vit. D group was divided into low (10 IU), normal (1,000 IU), and high (5,000 IU) subgroups. The weight gain and food efficiency ratios of the rats were not significantly different with increasing dietary Ca levels. The absorption rates of 7 minerals (Ca, P, Mg, Fe, Zn, Cu, and Cr) were significantly decreased with increasing dietary Ca levels. Also, fecal excretion of P significantly increased with increasing dietary vit. D levels (p<0.05), and urine excretion of Fe was significantly increased with increasing dietary vit. D levels (p<0.001). The result indicated that higher Ca intake affected on bioavailability of other minerals, due to interactions among minerals in the process of intestinal absorption. However, vitamin D intake had no effect on bioavailability of several minerals. Therefore, it could be suggested that adequate Ca intake is important for balance of the minerals.

위화(胃火) 1호(號)로 호전(好轉)된 만성위염(慢性胃炎) 환자(患者) 치험(治驗) 2례(例)

이경민,이세연,임성철,서정철,한상원,Lee, Kyung-min,Lee, Se-yun,Im, Sung-chul,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.6

Objective: This study was designed to investigate the effect of Wihwa herbal-acupuncture on chronic gastritis. Methods: Wihwa herbal-acupuncture was administered two times a week. The following points were selected: CV12(中脘), CV13(上脘), S36(足三里), Liv3(太衝). We checked pain rating score(P.R.S.), visual analogue scale (V.A.S.) and Gastroscopy. Results: After 6 weeks of treatment, the patient showed that clinical symtoms was disappeared, Lee's P.R.S. changed from 77 to 8 and Park's P.R.S. from 55 to 0 and gastric erosion disappeared on gastroscopy. Conclusions: These results suggest that and Wihwa herbal-acupuncture has good effect on chronic gastritis. But further studies are required to concretely prove the effectiveness of Wihwa herbal-acupuncture for treating chronic gastritis.

엑시머레이저 굴절교정수술을 이용한 백내장 수술 후 잔여 난시에 의한 부등시의 교정

이경민,김은철,김만수,Kyung Min Lee,M,D,Eun Chul Kim,M,D,Man Soo Kim,M,D,Ph,D 대한안과학회 2008 대한안과학회지 Vol.49 No.10

Purpose: To evaluate the clinical effect of photorefractive keratectomy (PRK) and laser assisted in situ keratomileusis (LASIK) on eyes with anisometropia due to residual astigmatism after cataract surgery. Methods: We retrospectively reviewed the medical records of 11 eyes of 11 patients who had undergone cataract surgery from March 2002 to November 2005. PRK (2 eyes) and LASIK (9 eyes) was performed on 11 eyes with refractive myopic or mixed astigmatism over 1.5D after cataract surgery. Result: Before laser surgery, the mean astigmatism was 3.23±1.02D and the mean spherical equivalent (SE) was -2.27±1.43D. Six months after laser surgery, the mean SE was 0.66±0.58D and the mean astigmatism was 0.73±0.39D. The changes in mean manifest SE and astigmatism were statistically significant between paired preoperative and postoperative values (p<0.05). At 6 months after surgery, the mean uncorrected visual acuity and best corrected visual acuity significantly improved to 0.65±0.17 and 0.84±0.11, respectively. Three eyes (27.3%) developed mild haze and were treated without sequelae. There were no other complications. Conclusions: Excimer laser surgery appears to be a clinically useful procedure to correct residual astigmatism after cataract surgery. J Korean Ophthalmol Soc 2008;49(10):1589-1596

유산균이 Aspergillus parasiticus의 성장과 Aflatoxin $B_1$ 생성에 미치는 영향

이경민,김종규,Lee Kyung-Min,Kim Jong-Gyu 한국환경보건학회 2005 한국환경보건학회지 Vol.31 No.2

This study was performed to investigate the competitive effect of Leuconostoc mesenteroides and Lactobacillus plantarum on the growth and aflatoxin $B_1$ production of Aspergillus parasiticus. Leu. mesenteroides and Lac. plantarum were grown with A. parasiticus in a modified APT broth at $28^{\circ}C$ for 9 days. It was observed that the growth of A. parasiticus got lower when the two bacteria were inoculated simultaneously than when the mold grew alone. The pH of mixed culture of Leu. mesenteroides and Lac. plantarum showed significantly lower value than the pH of the pure culture of A. parasiticus (p<0.05). The acidity of the mixed culture group significantly increased compared with the control group (A. parasiticus alone group) (p<0.05). The aflatoxin $B_1$ production was significantly decreased in the mixed culture group than in the A. parasiticus alone group (p<0.05). Leu. mesenteroides showed the more efficient effect than Lac. plantarum. These results indicate that the two lactic acid bacteria have inhibitory effect on the growth and aflatoxin $B_1$ production of Aspergillus parasiticus.

Methyl fluoroperoxide와 fuoromethyl fluoroperoxides의 conformers와 isomers 구조에 대한 이론연구

이경민,성은모,Lee, Kyoung-Min,Sung, Eun-Mo 대한화학회 2011 대한화학회지 Vol.55 No.3

Methyl hydro-peroxide의 methyl group과 O-H에 F를 치환 시킨 fluoromethyl fluoroperoxide($CH_nF_{3-n}OOF$)의 안정한 conformers와 isomers에 대하여 MP2/6-311G(d,p) 방법과 B3LYP/6-311++G(d,p) 방법으로 최적화 계산을 수행하였고 vibrational frequencies를 구하였다. $CH_3OOF$와 $CH_2FOOF$, $CHF_2OOF$, $CF_3OOF$ 분자 모두 가장 안정한 형태는 skew 구조로 나타났으며 $CH_3OOH$와 비교할 때 대단히 짧은 O-O 결합길이를 갖는다. Trans, cis conformers의 경우 skew 형태보다 8-12 kcal/mol 정도 높은 에너지를 갖으며 O-O 결합길이는 훨씬 길어진다. $CH_2FOOF$, $CHF_2OOF$, $CF_3OOF$ 분자들은 methyl group의 F에 의한 induction 효과로 짧은 C-O 결합길이를 갖고 O-F 결합길이는 길어지나 치환된 F 원자의 수에 따른 구조변화는 그리 크지 않다. The ab initio calculations for fluoromethyl fluoroperoxides have been carried out using MP2/6-311G(d,p) and B3LYP/6-311++G(d,p) method. The structural optimizations were performed for several isomers and conformers of methyl fluoroperoxide, $CH_3OOF$ and the vibrational frequencies were calculated. The most stable conformer of $CH_3OOF$ is skew form and has fairly short O-O bond distance. The trans and cis conformers have 8-12 kcal/mol higher energies than skew form and the other isomers are very unstable. The structures of $CH_2FOOF$, $CHF_2OOF$ and $CF_3OOF$ are also optimized and vibrational frequencies were calculated. These molecules also have skew forms as the lowest energy conformers. The O-O bond distances are longer and C-O bond distances are shorter than $CH_3OOF$, but the structural parameters are almost independent of the number of fluorine atoms in methyl group.

Proteomic Analysis기법을 이용한 홍화자약침액(紅花子藥鍼液)이 간암세포주(肝巖細胞柱)의 유전자(遺傳子) 발현(發顯)에 미치는 영향(影響)

이경민,임성철,정태영,서정철,한상원,Lee, Kyung-Min,Lim, Seong-Chul,Jeong, Tae-Young,Seo, Jung-Chul,Han, Sang-Won 대한약침학회 2005 Journal of pharmacopuncture Vol.8 No.2

Objective : It has long been known about the osteogenic effect of CTF-HAS on bone tissues. However, it has not been determined the effect of CTF-HAS on cancer cells. The purpose of this study is to screen the CTF-HAS mediated differentially expressed genes in cancer cells such as HepG2 hepatoma cells lines. Methods : CTF-HAS was prepared by boiling and stored at $-70^{\circ}C$ until use. For proteomic analysis, total protein was analyzed by 2D gel electrophoresis and Q-TOF mass spectrometer. Results : In proteomic analysis, three spots were identified by 2D-gel electrophoresis and Q-TOF analysis. One down-regulated protein was heat shock 70kDa protein 5 and up-regulated proteins were chaperonin and 2-phospho -pyruvate-hydratase ${\alpha}-enolase$ by 1.5mg/ml of CTF-HAS. Discussion : Proteomic analysis approach were performed to screen the differential expression genes. The screened genes will be used for the better understanding in therapeutic effect of CTF-HAS on cancer field.

대용량 전력저장용 이차전지 세라믹 소재 개요 및 향후 전망

이경민,윤중락,Lee, Gyeong-Min,Yun, Jung-Rak 한국전기전자재료학회 2013 전기전자재료 Vol.26 No.12

옻에 대한 문헌적 고찰

이경민,권기록,최성모,김태희,Lee, Kyoung-Min,Kwon, Ki-Rok,Choi, Sung-Mo,Kim, Tae-Hee 대한약침학회 2002 Journal of pharmacopuncture Vol.5 No.1

Objective: It will be examined in this research whether Lacquer poison can be used as an distinguished treatment to cure incurable diseases by considering literature existing and various papers. Method: I studies origin, alias, species, toxicity, effect, treatment, component, medical action and contraindication of Rhus vemiciflua stokes through various kinds literatures. Results: Sap of Rhus vemiciflua stokes that is used for medical purposes, has an effect on anti-tumor, anti-oxidation, hangover cure, and gastritis suppression. Even though urushiol and fIavonoids, the main ingredient of lacquer, has medical cure effects. but urushiol results in a dermatropic allergy. Sincc xylem of a Rhus vemiciflua stokes, however. does not induce the allergy but has medical efficacy, research on this topic is needed.

급성 폐쇄각녹내장에서 합병증을 중심으로 본 초음파유화술의 임상결과

이경민,이현수,김만수,Kyung Min Lee,Hyun Soo Lee,Man Soo Kim 대한안과학회 2009 대한안과학회지 Vol.50 No.1

Purpose: To evaluate the intraoperative and postoperative complications and outcomes of phacoemulsification of cataract in eyes with prior iriodotomy for acute angle closure glaucoma. Methods: This retrospective case-control study included 30 eyes which underwent phacoemulsification. All 30 eyes had prior acute angle closure treated by laser iridotomy (ACG group). A second group that had phacoemusification for cataract only served as control (Control group). Results: The ACG group showed significantly shallow anterior chamber (1.56±0.18 mm) and short axial length (22.32±0.60 mm). At 2 months after surgery, visual acuity was improved in both groups and IOP was significantly decreased in the ACG group. Posterior synechiae, small pupil and zonulysis were more commonly found in the ACG group than the control group. Intraoperative iris trauma and postoperative persistent mydriasis were also more common in the ACG group. Conclusions: During cataract surgery in eyes with prior iriodotomy for acute angle closure glaucoma, there are many preoperative risk factors such as shallow anterior chamber, zonulysis, and small pupil. These increase the risk of posterior capsule rupture and bullous keratopathy. To reduce the complications and improve the visual acuity, a careful preoperative examination and proper intra- and post-operative management by skillful surgeons are needed.

WebRTC VC응용의 접근성 및 편의성 향상기술 구현

이경민,조진용,공정욱,Lee, KyoungMin,Jo, Jinyong,Kong, JongUk 한국정보통신학회 2016 한국정보통신학회논문지 Vol.20 No.8

본 논문은 WebRTC 화상회의 응용의 서비스 접근성 및 이용 편의성 향상 방안을 소개한다. 화상회의 응용에 대한 접근성 향상을 위해서는 통합 인증 등을 적용해 사용자 로그인 처리를 간소화 할 필요가 있다. 또한 사용자 경험을 높이고 관리 비용을 낮추기 위해 서비스 사용성과 관리 편의성을 높여야 한다. 본 논문에서 개발한 화상회의 응용은 SAML 기반의 연합 ID 관리 체계를 적용하여 서비스 접근성을 높였으며 표준화된 인증 및 인가 기능을 제공해 간접적으로 개인정보보호를 강화할 수 있다. 또한 REST API를 통해 화상회의 세션의 개설 및 참여, 조회 기능을 제공해 서비스 사용자에게 높은 이용 편의성을 제공하며 모니터링, 이용이력관리 등을 통해 서비스 제공자의 관리 편의성을 높인다. 본 논문에서는 적용된 연합 ID 관리체계와 REST API를 소개하고 구현 결과를 통해 서비스 실현 가능성을 검증한다. This paper introduces technical methods to improve the accessibility and usability of a WebRTC video conference (VC) application. Simplified login is essential, by applying such as single sign-on (SSO) to improve the accessibility of VC applications. High usability and manageability are also necessary to attract more users, enhance user experiences, and save service management cost. The proposed VC application leverages SAML-based federated identity management (FIM) to enable higher service accessibility. Users can access the application with their organizational ID and SSO authentication. The FIM eases user ID management and indirectly strengthens privacy information protection. Proposed web application has high usability and manageability because users and/or administrators can easily create, join, monitor, or tear down VC sessions through RESTful web service (REST API). We verify the feasibility of the VC application after illustrating the SAML-based identity federation and the designed REST API.