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보중익기탕증(補中益氣湯證)의 병인론(病因論)적 분석을 위한 설문문항(說問問項) 개발(開發)
윤태득 ( Tae-deug Yoon ),박영재 ( Young-jae Park ),박영배 ( Young-bae Park ),이상철 ( Sang-chul Lee ),오환섭 ( Hwan-sup Oh ) 대한한의진단학회 2007 大韓韓醫診斷學會誌 Vol.11 No.1
Background: Bojungikgitang is one of the most common herbs in oriental medicine. Principally, this medicine heals illness from overwork and stress. Therefore, it is frequently used in the ancient community. Because of insufficiency in data, objective judgements are difficult in remedial effects by Bojungikgitang. In order to make objectivity diagnose data, this research is developed. Purpose: The aim of the research is to make questionnaire for the medicine and the objective is to sell to the public from the local clinic. Methods: The questionnaire which includes symptoms and signs for diagnose of Bojungikgitang is studied by the Delphi method and average value. Results: By the Delphi method and average value, 25 Items of questionnaires are choosen for the research. Conclusions: Further research is necessary for modification of questionnaire by statistics and certification by clinical trial. The statistics and verification by clinical trial is necessary with modification for further research.
보중익기탕증(補中益氣湯證)의 병인론적(病因論的) 분석을 위한 설문문항(說問問項) 개발(開發)(II)
윤태득 ( Tae-deug Yoon ),박영재 ( Young-jae Park ),이상철 ( Sang-chul Lee ),박영배 ( Young-bae Park ),오환섭 ( Hwan-sup Oh ) 대한한의진단학회 2007 大韓韓醫診斷學會誌 Vol.11 No.2
Background and purpose: We previously developed questionnaire of Bojungikgitang systom on the Delphi method through the pathogenesis analysis. But developed a questionnaire was not verified in the clinical. So, to ensure objectivity, quantification and validity, verification is needed for questionnaire items before applying a clinical. On this study, we looked at whether questionnaire items had been validity in the clinical. Methods: Surveys conducted about 191 patients at 12 oriental medicine hospitals. Among them, patients with Bojungikgitang systom(group I) were 95, and patients with no Bojungikgitang systom(group II) were 96. We calculated that the sum of each item in the survey and then the sum was reviewed statistically significant difference through Independent samples T test between group I and Ⅱ. Results: Between group I and Ⅱ, the total sum survey of the percent difference is meaningful (P<0.05). Conclusions: Reliability analysis of the Bojungikgitang systom survey research is needed in the future. Also I think that research should proceed about a lot of people.
대장에 다발성 종주궤양을 가진 장형 Behcet`s Disease 1예 보고
강영진,옥종한,박희욱,윤태득,이진연,김미경,서달덕 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.3
We presented here a rare case of intestinal Behecet's disease simulating Grohn's disease. A 20 year old female complained of recurrence of oral ulcer, genital ulcer, arthralgia, erythema nodosum, abdominal pain and diarrhea, but she had no anal ulcer or anal fistulas. The colonoscopic examanation disclosed diffuse colonie involvement with multiple longitudinal ulcers and inflammatory pseudopolyposis. In hospital, she received ileocecectomy because of distal ilea perforation. Postoperative specimen showed multiple geographic ulcer on ileocecal region, creeping mesenteric fat and thickening of cecal wall. Pathological examination showed perivasculitis, transmural inflammation, fissuring, multiple lymph follicles which are compatible with intestinal Behect's disease. There were no granuloma sugges tive of Crohn's disease. Clinically, the patient met the international criteria of Behcet's disease. Punched out ulcer in the ileocecal region and pathological findings described above confirmed the diagnosis of intestinal Behcet's disease.
혈액투석 환자의 투석간 체중증가에 미치는 Angiotensin 전환효소 억제제의 효과
김미경(M . K . Kim),윤태득(T . D . Yoon),서달덕(D . D . Su),이진연(J . Y . Lee),김용근(Y . K . Kim),이형걸(H . G . Lee),김태익(T . Y . Kim),최영선(Y . S . Choi),공진민(J . M . Kong) 대한내과학회 1997 대한내과학회지 Vol.52 No.5
N/A Objective: To determine the efficacy of ACE inhibitor on reducing the interdialytic HW gain of patients on maintenance hemodialysis. Methods: A randomized, double blind, placebo controlled crossover study, consisting of one 4-week baseline period and two 4-week treatment periods, which were interposed by a 2-week washout period, was conducted on 21 non-diabetic ESI4D patients on hemodialysis. During the treatment periods, patients were given either fosinopril 10 mg/day or a placebo. Interdialytic BW gain was recorded during the study period and BUN, plasma Na, osmolarity and the agiotensin II level were measured at the end of the baseline and treatment periods. Results: Eight patients were excluded from the study due to incompliance to medication and 13 patients remained in the study. During the baseline period, no correlation was found between interdialytic weight gain and BUN, Na, osmolarity and angiotens in II. There was no difference in the interdialytic weight. increment between the fosinopril-treated (1.0±0.1kg/day, mean±SE) and placebo-treated period (1.0±0.1), The weight increment in both periods was significantly less than that in the baseline period (1.2±0.2), suggesting a psychological influence of both medications on thirst. However, in 8 patients who gained 1.0 kg/day or more during the baseline period, the interdialytic HW increment in fosinopril-treated period (1.3±0.1) was significantly less than that in the placebo period (1.4±0.1, p<0.05 by paired t test). Of these patients, 6 patients gained less and 2 patients showed no difference in the fosinopril period compared with the placebo period. Conclusion: ACE inhibitor may reduce interdialytic BW gain in hemodialysis patients with moderate to high interdialytic weight increment.
김미경,강영진,옥종한,박희욱,윤태득,서달덕,이진연 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.3
The occurrence of the small intestinal adenocarcinoma is infrequent and the primary adenocarcinoma of the jejunum is rare. The survival of adenocarcinoma of the small bowel does not improve over the past three decades. Although symptoms appeared to be of long duration, most patients were diagnosed with advanced disease. All reports agree that these tumors are difficult to achieve good examination of the small bowel by both clinician and radiologist, so it cause a significant delay in diagnosis. The survival of these tumors appear to correlate with stage at presentation, and therefore early and aggressive diagnostic intervention seems to improve the outlook. We report a case of primary jejunal adenocarcinoma assoeiated with iron deficiency anemia with literatures review.
김미경,강영진,이지현,박희욱,이진연,서달덕,윤태득,김태익,옥종한 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.4
Peritoneal mesothelioma is a rare disease which arises from the mesothelial lining cells in the peritoneum and spreads to the peritoneal wall, omentum and other abdomina1 organs. Aabestos is one etiologic factor and the other factors are genetic cause, radiation, exposure to toxic materials and recurrent yeritonitis. We experienced a case of multiple small nodular peritoneal mesothelioma after exposure to asbestos for over 20 years. He was a sailor and had worked in the engine department of the ship, in which he wrapped up the pipe of engine in asbestos. This person came to our hospital because of inconvenience due to a distended abdomen. Tumor markers were all within normal limits and there was no evidence of tuberculosis in the abdomen and chest. The CT findings of the abdomen were as follows: There was abundant ascites in the abdominal cavity and multiple small nodules on the parietal peritoneum and especially on the lower abdomen. The omentum thickened diffusely. It was difficult to distinguish from peritoneal mesothelioma and peritoneal carcinomatosis or intestinal tuberculosis. The laparoscopic findings were as follows: There were multiple small nodules on the parietal peritoneum and omentum. The small nodules were a gray white color and uneven compared to tuberculous peritonitis. Therefore, we observed the malignant mesothelial cells by means of the light microscope and electron microscope and concluded that this case was peritoneal mesothelioma.