침윤성 흉선종 -전산화 단층촬영 소견의 관찰-

윤춘식 대한영상의학회 1985 대한영상의학회지 Vol.21 No.2

In 6 cases of invasive thymoma proved histologically from 1981 to 1984 in Yonsei University Medical Center, the CT findings and pattern were analysed. The results were as follows 1. Of 6 cases, 4 were males and 2 were females. All cases were between 40-64 years and the average was 51 year lod. 2. Of 6 cases, 2 female patients were associated with myasthenia gravis. 3. By the histological examination, 2 were confirmed as mixed cell type, 2 spindle cell type, 1 lymphocytic type and 1 epithelial cell type. 4. CT findings of invasive thymoma were 1) A discrete but lobulated and irregular marginated soft tissue mass in the superoanterior mediastinum repalcing the normal mediastinal fat tissue. 2) Usually irregular low density areas within the mass suggesting central necrosis or calcification in 1 of 6 cases was noted. 3) Local invasiveness of the mass shown as obliteration of the normal far planes surrounding great vessels, irregular thickenings or nodular shadows of the pleura, di gphragm and pericardium and irregular and ragged tumor-lung interfaces if the tumor invaded to these structures. 4) Frequent extention of tumor to middle and post, mediastnum along pericardium or mediastinal pleura with resultant extrinsic indentation and/or invasion of the hilar region. 5) Extensive tumor infiltration to middle and post, mediastinum in 1 cases, indistinguishable from lymphoma. 6) Low attenuation numbered area of brain in another 1 case, but not confimed histologically.

초파리 rdgC 돌연변이체 단안 시각계의 퇴행현상

윤춘식,Yoon, Chun-Sik 한국현미경학회 1998 Applied microscopy Vol.28 No.3

The morphological phenotype on ocellus of Drosophila rdgC mutant was observed with electron microscope. The result showed the particular phenotype that was not found in other retinal degenarative mutants. The most distinct difference was the orientation of photoreceptor cells. The photoreceptor cells did not attached to corneagenous cells but dropped under corneagenous cells and assembled around newly formed space. Enormous multivesicle bodies caused by the degeneration of photoreceptor cells were frequently found. Rhabdomeres were also severely degenerated in consequence of the mutant. Another degeneration was found in a part of photoreceptor cell, but the degeneration of subrhabdomeric cisternae (SRC) was not found. It was a ovious difference of rdgC comparing with other two retinal degenerative mutants, rdgA and rdgB. As a result, rdgC mutant was affected on the attachment between photoreceptor cells and corneageneous cells, and it suggested the defect of cell-cell attachment. In addition, rdgC mutant was accompanied by the defect not only in retina but nerve system. The results were agreed to the reference discussion that the rdgC molecule is exist in the nerve.

초파리 단안 신경계의 미세형태학적연구

윤춘식 한국생명과학회 1999 생명과학회지 Vol.9 No.6

성층 초파리의 단안 신경계를 미세형태학적으로 연구 하였다. 단안은 수용기말단, 개재신경 그리고 신경교세포의 3종류로 구성되어 있다. 이들은 전자현미경 사진상에서 각기 다른 밝기를 보여주고 있으므로 쉽게 구분이 가능했다. 신경교세포 내에는 조면소포체가 풍부하게 존재하고, 수용기 말단과 개재신경내에는 신경세포에서 물질의 이동 통로인 미소관이 다수 관찰되었다, 수용기말단과 신경교세포를 연결해주는 capital projection이라는 인상적인 구조물이 관찰된다. 수용기 말단과 개재신경의 시냅스 활성부에 존재하는 리본모양의 구조물과 이들 주위에 모여있는 시냅스 소포들이 자주 관찰되었다. 그리고 단안 시신경이 최종적으로 집중되어 뇌로 신호를 전달해 주는 거대개재신경(giant interneuron)의 횡단 구조를 관찰 할 수 있었다. Ultrastructure of ocellar system was studied in adult Drosophila melanogaster. Ocellus was composed of terminal receptors, interneuron and glia. These three part showed different brightness each other and each component was distinct. In the glial cell, rER was abundant, and terminal receptors and interneuron showed numerous microtubules, special transporting system. The terminal receptors have particular structure referred as capital projection connecting the terminal receptor to glia. In synaptic active zone between terminal receptor and interneuron, ribbon-like structures and synaptic vesicles around the structures were frequently observed. In addition, the cross section of giant interneuron was also observed.

선교교육과 오순절 프락시스

윤춘식 고신대학교 선교연구소 2001 고신선교 Vol.- No.-

저항전분 현미로 제조한 스펀지케익의 품질특성

윤춘식,황진아,김현아,장윤희 (사)한국조리학회 2019 한국조리학회지 Vol.25 No.4

The purpose of this study was to manufacture sponge cakes using resistance starch that is beneficial to the health of modern people and to specify quality characteristics. Sponge cake was made by whipping eggs and sugar, mixing melted butter with powder, panning 250 g each, and baking in an oven at 180℃ and 180℃. The volume, weight, and height of sponge cake made with Control, SB, and SR were significantly different. The crude protein content of Control was the highest. The moisture content of SB and SR were higher than the Control. The hardness, gumminess, and chewiness were significantly different among the products but springiness and cohesiveness were not significantly different. The yellowness values of SR was significantly higher, the lightness values of SR was significantly lower. The internal structure of sponge cake, SR showed the best result. After the sensory evaluation, the crust color of Control, and crumb color of SR were preferred. The cell size of SR was the smallest, and the cell uniformity was the lowest. The softness of Control was the highest. The appearance and texture of Control were mostly preferred, but the taste, flavor, and overall acceptability of SR were favorite.

골단일 형질세포종 : 방사선학적 소견

윤춘식,김명준,안창수,서진석,신규호,Yoon, Choon-Sik,Kim, Myung-Joon,Ahn, Chang-Soo,Suh, Jin-Suck,Shin, Kyoo-Ho 대한근골격종양학회 2000 대한골관절종양학회지 Vol.6 No.2

목적 : 골단일 형질세포종의 방사선 소견을 알아보고자 하였다. 대상 및 방법 : 최근 5년동안 골단일 형질세포종으로 진단받았던 9례의 방사선 소견을 후향적으로 검토하였다. 이 중 2례는 골수검사 소견의 이상으로 대상에서 제외되었고 다른 2례는 전산화단층촬영(1례)와 자기공명영상(1례) 소견의 이상 소견에 의해 대상에서 제외되었다. 결과 : 5례 중 4례에서 단순방사선검사상 경화성 변연이 없는 지도 모양의 골파괴 소견을 보였으며 대퇴골에서 발생한 1예는 골경화증 병변을 보였다. 전산화단층촬영과 자기공명영상 검사는 단순방사선검사에 비해 소주형성을 한 골파괴와 연부조직 침범 등 보다 많은 정보를 보여주었다. 4례의 자기공명영상에서 T 1강조영상에서는 비교적 고신호강도, T2강조영상에서 는 근육보다 약간 높은 중등도 신호강도를 보여주었다. 1례에서는 광범위한 연부조직 침범이 있었고, T1강조영상에서 같거나 저신호강도로, T2강조영상에서는 비균일한 고신호강도를 보이는 다발성 괴사가 있었다. 조영증상 T 1강조영상에서는 괴사부위를 제외한 병변의 강한 조영증강소견이 보였다. 결론 : 전산화단층촬영과 자기공명영상 검사는 골단일 형질세포종의 특징적인 소견의 일부를 보여줄 수 있고 형질세포 침윤이 있는 다른 부위를 찾을 수 있다. 이러한 것들이 골단일 형질세포종의 진단과 치료에 도움을 줄 수 있을 것이다. Purpose : We examined the patients to evaluate the radiologic findings of solitary plasmacytoma of the bone. Materials and Methods : We retrospectively reviewed radiologic findings of 9 cases with solitary plasmacytoma of the bone (SPB) for recent 5 years, but 2 cases were not included this study due to an abnormal finding of bone marrow and another 2 cases were not included due to an abnormal manifestations of computed tomography (n=1) and MRI (n=1). Results : Among 5 cases, 4 cases had an osteolytic bone destruction and 1 case had an osteosclerotic bone destruction on the plain radiograph. Computed tomography and MRI showed more informations about trabeculated bone destruction and the soft-tissue extension of the lesion comparing to plain radiographs. The MRI finding of SPB in 4 cases showed a relatively high signal intensity on T1-weighted image and intermediate signal intensity on T2-weighted image, on which the signal intensity of the lesion is slightly higher than that of the muscle. One case had an extensive soft-tissue involvement and multiple necrosis, which presented iso to low signal intensity on T1-weighted image and high heterogeneous signal intensity on T2-weighted image. The Gadolinium-enhanced T1-weighted images of 5 cases showed diffusely strong enhancement of the lesion except on the necrosis areas. Conclusion : Computed tomography and MRI may present some characteristics of SPB and demonstrate another foci of plasma cell infiltrates, so these can be helpful for the diagnosis and treatment of SPB.

고령운전자 교통안전 의무교육의 효과에 관한 연구

윤춘식,김상구 대한교통학회 2019 대한교통학회 학술대회지 Vol.81 No.-

초파리 rdgA 시각돌연변이체 단안의 형태적 연구

윤춘식 한국생명과학회 1999 생명과학회지 Vol.9 No.3

Ocellar morphological abnormality was studied in Drosophila rdgA mutant. In the mutant, ocellar photoreceptor cells were generally affected by the defection of rdgA molecules. Among organelles of photoreceptor cell, rhabdomeres were remarkably degenerated. The rdgA molecule, diacylglycerol kinase, was localized around SRC just below the rhabdomeric region. As a secondary phenomenon of photoreceptor degeneration, rER, multivesicular body and multilamella body were appeared in cytoplasm and these were known as to clean the cellular debris. These morphological abnormality was generally observed in degenerating cells. In Drosophila mutant, the degeneration of ocellar photoreceptor cell was facilitated to time. More intense morphological defection was observed in rdgA^{ks60} rather than in yw;rdgApc47.

북한 「사회주의 교육에 관한 테제」의 내용과 교육방법

윤춘식 ACTS 북한선교학회 2003 북한선교 Vol.2 No.-

전산화단층촬영을 이용한 정상인 뇌하수체의 방사선학적 고찰

윤춘식 대한영상의학회 1987 대한영상의학회지 Vol.23 No.3

Direct coronal computed tomography with 1.5mm contiguous scanning was done in total 95 cases, who had o clinical evidence of pituitary and hypothalamic disease. The evaluation of pituitary height, width, upper surface contour and density was done and the pituitary stalk was also evaluated. RESULT : 1. Total 95 cases were 45 males and 50 females. 2. The average height of mormal pituitary gland was 5.72$\pm$1.44mm in female and 5.37$\pm$1.17mm in male. There was no significant difference of pituitary height between male and female. 3. The pituitary height was decreased according to the increased age both in male ad female except prepubertal age. 4. The group between 15-30 year old age showed significantly increased pituitary height comparingto the remained age group both in male and female. 5. The upper limit of mormal pituitary height in 95% confidence level was 7.95-0.011xage infemale and 7.4-0.013xage in male. 6. The upper surface contour of normal pituitary gland were convex in 14 cases, flat in 58 cases adn concave in 23 cases. There was a significant correlation between the height and upper surface contour of putuitary gland. 7. The average width of normal pituitary gland was 13.4$\pm$1.74mm in female and 13.69$\pm$2.3mm in male. There was o significant difference between those of female and male. 8. The focal low density of normal pituitary gland was noted in only 8.4% and its size was always below 3mm. 9. Te pituitary stalk can be seen in 94.7% by direct coronal CT scanning and it was located at the midline. 10. There were nosignificant difference in pituitary height and width accordig to the menopause or the marrige.