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윤애라 ( Ae Ra Yoon ),김서희 ( Seo Hee Kim ),김하정 ( Ha Jeong Kim ),배덕수 ( Duk Soo Bae ),이정원 ( Jeong Won Lee ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.9
Primary signet ring cell carcinoma of the cervix is extremely rare. A 47-year-old woman visited for postcoital vaginal bleeding during the last six months. Gynecologic examination revealed mild cervical erosion and touch bleeding. Colposcopic punch biopsy revealed a signet ring cell type of mucinous adenocarcinoma. The patient underwent radical hysterectomy with bilateral salpingo-oophorectomy, pelvic lymph node dissection, and para-aortic lymph node dissection. Microscopically, the tumor mainly consisted of two different types of cells; mixed signet ring cell carcinoma (70%) and mucinous carcinoma of intestinal type (30%). The patient died in 6 months after operation. The prognosis of primary signet ring cell adenocarcinoma of the uterine cervix is still unclear because of the extremely rare incidence of cases. In this case, we could suggest that this type of carcinoma has an aggressive behavior.