주관적기억장애 환자의 미래계획기억: 예비 연구

윤보라,정성우,심용수 대한치매학회 2008 Dementia and Neurocognitive Disorders Vol.7 No.1

Background: Subjective memory impairment (SMI), defined by memory complaints with normal age-, gender- and education-adjusted cognitive performance, is a frequent phenomenon in elderly people. According to longitudinal studies, SMI is probably a predictor for future mild cognitive impairment (MCI) and dementia. However, there has been no objective neuropsychological test for evaluating SMI, and previous studies relied solely on patients’ subjective complaints. Thus, our goal was to make an objective standard that is useful in distinguishing SMI from normal aging as well as MCI by considering prospective memory (PM) as a higher level of memory. Methods: The study participants included seven healthy controls, 25 individuals with SMI and eight patients with amnestic MCI (aMCI). The inclusion criteria for SMI were 1) over 55 yr, 2) sustained subjective memory complaints, 3) normal general cognition, 4) no abnormality (within-1SD) in neuropsychological battery and 5) no depression. aMCI was followed by Pitersen’s criteria. To assess prospective memory, the Cambridge Behaviour Prospective Memory Test, which consisted of four time-based and four event-based tasks, was performed. Subsequently, scores from Korean Mini-mental Status Examination (K-MMSE), the 20 min delayed recall Seoul verbal learning test (SVLT), and individual task scores of PM and total PM scores were compared among each group. Results: There were no significant group differences in age, education, sex, K-MMSE score and time-based PM among the three groups. However, SVLT scores and total PM scores showed a significant decline in the aMCI group, unlike that for the SMI and control groups. Moreover, eventbased PM score was significantly decreased stepwise in both SMI and aMCI groups. Conclusions: These findings suggest that PM, especially for event-based tasks, is sensitive for detecting the earliest cognitive changes associated with SMI, and PM tasks seem to be more susceptible to the early cognitive decline than retrospective memory tasks. As PM is a sensitive predictor for future cognitive decline, SMI may be a first manifestation of future dementia in the elderly regardless of depression. Future research will help determine the clinical usefulness of PM tasks. Background: Subjective memory impairment (SMI), defined by memory complaints with normal age-, gender- and education-adjusted cognitive performance, is a frequent phenomenon in elderly people. According to longitudinal studies, SMI is probably a predictor for future mild cognitive impairment (MCI) and dementia. However, there has been no objective neuropsychological test for evaluating SMI, and previous studies relied solely on patients’ subjective complaints. Thus, our goal was to make an objective standard that is useful in distinguishing SMI from normal aging as well as MCI by considering prospective memory (PM) as a higher level of memory. Methods: The study participants included seven healthy controls, 25 individuals with SMI and eight patients with amnestic MCI (aMCI). The inclusion criteria for SMI were 1) over 55 yr, 2) sustained subjective memory complaints, 3) normal general cognition, 4) no abnormality (within-1SD) in neuropsychological battery and 5) no depression. aMCI was followed by Pitersen’s criteria. To assess prospective memory, the Cambridge Behaviour Prospective Memory Test, which consisted of four time-based and four event-based tasks, was performed. Subsequently, scores from Korean Mini-mental Status Examination (K-MMSE), the 20 min delayed recall Seoul verbal learning test (SVLT), and individual task scores of PM and total PM scores were compared among each group. Results: There were no significant group differences in age, education, sex, K-MMSE score and time-based PM among the three groups. However, SVLT scores and total PM scores showed a significant decline in the aMCI group, unlike that for the SMI and control groups. Moreover, eventbased PM score was significantly decreased stepwise in both SMI and aMCI groups. Conclusions: These findings suggest that PM, especially for event-based tasks, is sensitive for detecting the earliest cognitive changes associated with SMI, and PM tasks seem to be more susceptible to the early cognitive decline than retrospective memory tasks. As PM is a sensitive predictor for future cognitive decline, SMI may be a first manifestation of future dementia in the elderly regardless of depression. Future research will help determine the clinical usefulness of PM tasks.

대 전수질 동맥 발견을 위한 척추 자기공명 혈관조영술의 유용성

윤보라,이준우,전우선,곽규성,이종세,김성현,명재성,정희선,김주형,김재형,강흥식 대한영상의학회 2007 대한영상의학회지 Vol.56 No.1

A Survey on Current Trends of Breast Imaging Practices in Korea

윤보라,김선미,장미정,조나리야,한부경 대한영상의학회 2019 대한영상의학회지 Vol.80 No.5

Purpose This study aimed to analyze the current practices of breast imaging among Korean radiologists. Materials and Methods We invited members of the Korean Society of Breast Imaging (KSBI) working as breast radiologists to participate in a survey on the current practices in breast imaging, and investigated how quality assurance (QA), medical audits, and imaging-histologic discordance were conducted. Results The survey involved 312 members of the KSBI, and 116 (37%) responded to the 21 questions in the questionnaire. Most of the respondents were women (87%), aged below 50 years (82.7%), and working at university or tertiary hospitals (68.1%), who had varying levels of experience in breast imaging. Of the 116 respondents, 114 (96.6%) followed the Breast Imaging Reporting and Data System (BI-RADS) to interpret breast imaging. Out of 116, 72 (62.1%) interpreted 20 or more mammograms per day, 84 (72.4%) performed 10–30 breast ultrasound scans per day, and 65 (56%) interpreted fewer than 5 breast MRI scans per day. Among the respondents, 82% performed mammography QA, 76.9% evaluated imaging-histologic correlations, and only 38.9% performed medical audits. Conclusion The institutions and working patterns of breast radiologists were diverse. Although many respondents did not conduct medical audits, most of them followed BI-RADS when interpreting breast imaging, performing QA, and evaluating imaging-histologic correlations.

온라인 페미니즘

윤보라 도서출판여이연 2014 여성이론 Vol.- No.30

병원 청소근로자의 업무상 손상 양상과 관련요인

윤보라,김숙영 한국직업건강간호학회 2015 한국직업건강간호학회지 Vol.24 No.3

Breast Magnetic Resonance Imaging-Guided Biopsy

윤보라,김선미,장미정,조나리야,문우경,김학희 대한영상의학회 2016 대한영상의학회지 Vol.74 No.6

Despite the high sensitivity of breast magnetic resonance imaging (MRI), pathologic confirmation by biopsy is essential because of limited specificity. MRI-guided biopsy is required in patients with lesions only seen on MRI. We review preprocedural considerations and the technique of MRI-guided biopsy, challenging situations and troubleshooting, and correlation of radiologic and pathologic findings.

Factors Associated with Lung Function Recovery at the First Year after Lung Transplantation

윤보라,박지은,김치영,박무석,김영삼,정경수,송주한,백효채,이진구,김송이 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.9

Purpose: Post-operative pulmonary function is an important prognostic factor for lung transplantation. The purpose of this studywas to identify factors affecting recovery of forced expiratory volume in 1 second (FEV1) at the first year after lung transplantation. Materials and Methods: We retrospectively reviewed the medical records of lung transplantation patients between October 2012and June 2016. Patients who survived for longer than one year and who underwent pulmonary function test at the first year of lungtransplantation were enrolled. Patients were divided into two groups according to whether they recovered to a normal range ofFEV1 (FEV1 ≥80% of predicted value vs. <80%). We compared the two groups and analyzed factors associated with lung functionrecovery. Results: Fifty-eight patients were enrolled in this study: 28 patients (48%) recovered to a FEV1 ≥80% of the predicted value, whereas30 patients (52%) did not. Younger recipients [odds ratio (OR), 0.92; 95% confidence interval (CI), 0.87–0.98; p=0.010], longerduration of mechanical ventilator use after surgery (OR, 1.14; 95% CI, 1.03–1.26; p=0.015), and high-grade primary graft dysfunction(OR, 8.08; 95% CI, 1.67–39.18; p=0.009) were identified as independent risk factors associated with a lack of full recovery oflung function at 1 year after lung transplantation. Conclusion: Immediate postoperative status may be associated with recovery of lung function after lung transplantation.

방사선 치료와 연관된 척추 부신경병증

윤보라,나상준,김용덕,이기욱 대한임상신경생리학회 2010 Annals of Clinical Neurophysiology Vol.12 No.2

책 읽어주기가 초등학교 4학년 학생들의 어휘력 향상에 미치는 영향에 관한 연구

윤보라 한국독서교육연구학회 2013 한국독서교육학회지 Vol.1 No.2

이 연구의 목적은 책 읽어주기가 어휘력 향상에 미치는 영향을 파악하는데 있다. 연구의 목적을 달성하기 위하여 성남시에 소재하고 있는 1개의 초등학교 4학년, 50명을 대상으로 통제집단에게는 학생 스스로 책을 읽게 하고, 실험집단에게는 책을 읽어주었다. 그 결과, 책 읽어주기가 학생 스스로 책을 읽는 경우보다 어휘력 향상에 효과가 있으며 이해도에서도 긍정적인 결과를 얻을 수 있었다.

A Microemulsion System for Printable Colorimetric Conjugated Polymer Supramolecules

윤보라,함대영,김종만 한국고분자학회 2010 한국고분자학회 학술대회 연구논문 초록집 Vol.2010 No.10