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저령 및 복령 煎湯液이 白鼠의 腎臟機能, Renin 活性度, 血漿 Atrial Natriuretic Peptide 및 Aldosterone 濃度에 미치는 影響
兪閏朝,李昊燮 圓光大學校 韓醫學硏究所 1996 원광한의학 Vol.6 No.1
The aim of this experiments was to investigate the effect of Polyporus Umbellatus and Hoelen water extracts on the renal function, plasma renin activity and plasma levels of atrial natriuretic peptide and aldosterone in rats. The results of this study were as follows: 1. Water balance decreased significantly after the administration of Polyporus Umbellatus 0.4㎖/㎏, and 0.8㎖/㎏. 2. Urine volume increased significantly after the administration of Polyporus Umbellatus water 0.4㎖/㎏, 0.8㎖/㎏ water extracts, but it decreased significantly after the administration of Hoelen 0.4㎖/㎏. 3. Urinary excretion of sodium increased significantly after the administration of Polyporus Umbellatus 0.4㎖/㎏ and Hoelen 0.8㎖/㎏. 4. Urinary excretion of potasium increased significantly after the administration of Polyporus Umbellatus 0.4, 0.8㎖/㎏ but it decreased significantly after the administration of Hoelen 0.4, 0.8㎖/㎏. 5. Urinary excretion of chloride increased significantly after the administration of Polyporus Umbellatus and Hoelen water extracts. 6. Free water clearance increased significantly after the administration of Polyporus Umbeilatus 0.8㎖/㎏ and Hoelen 0.4㎖/㎏. 7. Urinary excretion of creatinine increased significantly after the administration of Polyporus Umbellatus 0.4, 0.8㎖/㎏ and Hoelen 0.8㎖/㎏. 8. Plasma levels of atrial natriuretic peptide (ANP) increased significantly after the adminstration of Polyporus Umbellatus 0.4㎖, 0.8㎖/㎏, but it decreased significantly after the administration of Hoelen 0.4, 0.8㎖/㎏. 9. Plasma levels of aldosterone decreased significantly after the administration of Polyporus Umbellatus water extracts are related to the changes of glomerular fitration rate, urinary excretion of electrolytes and plasma levels of atrial natriuretic peptide and aldosterone.
유윤조,李昊燮 한국전통의학연구소 1999 한국전통의학지 Vol.9 No.1
The aim of the experiments was to investigate the effect of Fructus Tribuli on the blood pressure, plasma renin activity, plasma levels of aldosterone and atrial natriuretic peptide (ANP) in spontaneously hypertensive rats (SHR). The results of this study were as follows: 1. Systolic blood pressure decreased significantly after the administration of Fructus Tribuli water extract 0.03 ㎖/200 g. 2. Plasma renin activity and plasma levels of aldosterone were not changed after the administration of Fructus Tribuli water extracts. 3. Plasma levels of atrial natriuretic peptide (ANP) decreased significantly after the administration of Fructus Tribuli water extracts.
兎絲自 煎湯液이 自然發證 高血壓 白鼠의 血壓에 미치는 影響
유윤조 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.1
The aim of the experiments was to investigate the effect of Semen cuscutae on the blood pressure, plasma renin activity, plasma levels of aldosterone and atrial natriuretic peptide(ANP) in spontaneously hypertensive rats (SHR). The results of this study were as follows: 1.Systolic blood pressure was decreased significantly after the administration of Semen cuscutae water extracts. 2.Plasma renin activity was increased significantly after the administration of Semen cuscutae water extract 0.12㎖/200 g. 3.Plasma levels of aldosterone was increased significantly after the administration of Semen cuscutae water extract 0.12㎖/200 g. 4.Plasma levels of atrial natriuretic peptide(ANP) was decreased significantly after the administration of Semen cuscutae water extracts. Key word : Semen cuscutae, blood pressure, plasma renin activity, aldosterone, atrial natriuretic peptide
忍冬藤 전탕액이 자연발증 고혈압 백서의 혈압에 미치는 영향
유윤조 대한동의생리학회,대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.6
The aim of the experiments was to investigate the effect of Lonicera Japonica water extracts on the blood pressure, plasma renin activity, plasma levels of aldosterone and atrial natriuretic peptide (ANP) in spontaneously hypertensive rats (SHR). The results showed that systolic blood pressure in the group of adminstration of Lonicera Japonica water extract 0.25 ㎖/kg was decreased significantly from 7 days after administration but plasma renin activity and plasma levels of aldosterone were increased significantly. By contrast, In the group of administration of Lonicera Japonica water extract 0.5 ㎖/kg, systolic blood pressure was not changed significantly compared with 0.25 ㎖/kg administration group. These results suggest that the effects of administration of Lonicera Japonica 0.25 ㎖/kg on blood pressure are related to the secretion of hormone with body fluid metabolism.
토사자(兎絲子) 약침(藥鍼)이 자연발증(自然發證) 고혈압(高血壓) 백서(白鼠)의 혈압(血壓)에 미치는 영향(影響)
유윤조,한정우,육태한,이호섭,Yu Yun-Cho,Han Jeong-Woo,Yuk Tae-Han,Lee Ho-Sub 대한침구의학회 1998 대한침구의학회지 Vol.15 No.2
The aim of the experiments was to investigate the effect of Semen Cuscutae aqua-acupuncture at the meridian point BL 20(脾兪) and BL 23(賢兪) on the blood pressure, plasma renin activity, plasma levels of aldosterone and atrial natriuretic peptide (ANP) in spontaneously hypertensive rats (SHR). The results of this study were as follows: 1. Systolic blood pressure was decreased significantly after Semen Cuscutae aqua-acupuncture at the meridian point BL 20, BL 23. 2. Plasma renin activity was increased significantly after Semen Cuscutae aqua-acupuncture at meridian point BL 23, BL 20. 3. Plasma levels of aldosterone was increased significantly after Semen Cuscutae aqua-acupuncture at the meridian point BL 20. 4. Plasma levels of atrial natriuretic peptide (ANP) was increased significantly after Semen Cuscutae aqua-acupuncture at the meridian point BL 23, but it was decreased significantly after Semen Cuscutae aqua-acupuncture at the meridian point BL 20. These results suggest that the changes of the depressor response after Semen Cuscutae aqua-acupuncture at the meridian point BL 20, BL 23 are related to the changes of the plasma renin activity, plasma levels of atrial natriuretic peptide (ANP) and aldosterone.