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류진호,정경운,위준선,문정미,전병조,문원식,김용권,소정일,허탁,민용일 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4
Background: Although cardiopulmonary resuscitation(CPR) is a very effective therapy in cardiac arrest, it is hard to prove the true effectiveness of CPR. Several studies about out-of-hospital and emergency department CPR exist, but only a few reports about in-hospital CPR are available. This study was designed to investigate in-hospital cardiac arrest, to analyze the result of CPR, and to evaluate the problems associated with in-hospital CPR. Methods: A clinical analysis of 71 cases of in-hospital CPR announcement from January 2000 to August 2000 was performed. The initial rhythm on cardiac arrest, return of spontaneous circulation(ROSC), and the survivals were analyzed in the case of the 46 true cardiac arrest patients. Results: During 8 months, there were 71 cases of in-hospital CPR announcement. Among them, there were 46 cases of true cardiac arrest and 25 cases of non-cardiac arrest. Of the 46 true cardiac-arrest cases, 27(58.7%) experienced ROSC, 15(32.6) survived for over 24 hours, and 7(15.2%) survived to be discharged. The initial rhythms on cardiac arrest were 30 cases(65.2%) of asystole, 14(30.4%) of PEA(pulseless electrical activity), and 2(4.3%) of ventricular fibrillation, with ROSC being 17 cases(56.7%), 9(64.3%) and 1(50.0%) cases and discharged survivors being 4 cases(13.3%), 3(21.4%) and 0(0.0%) cases, respectively. Conclusion: Extraordinarily high proportions of asystole and PEA were seen in the initial rhythm of cardiac arrest, and those were associated with high survival rates. Although further study is needed to evaluate the course leading to this high proportion of asystole and PEA, this result suggests that if the EMS system in the hospital is activated promptly and systematically, a better outcome will be achieved in case of cardiac arrest with asystole and PEA.
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응급실에 내원한 환자에서 어지럼증의 원인과 임상양상의 분석
문원식,정경운,위준선,문정미,전병조,김용권,소정일,류진호,허탁,민용일 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3
Background: Recently, The number of patients who have been complaining of the vertigo or dizziness has been increasing due to rapid growth of elderly population and senile disease. The differentiation of dizzy patients is not familiar to most emergency physicians. This study was designed to differentiate true vertigo and to investigate the clinical difference among central vertigo, peripheral vertigo, and other causes of dizziness. Methods: The authors analyzed the cases of 237 dizzy patients who visited the emergency department of Chonnam University Hospital during the recent 2 years. For the base of dizziness, associated past illnesses, severity, nystagmus type, and the causes of central and peripheral vertigo. Results: Female patients were 142(59.9%) and male patients were 95(40.1%). The most common age group was the 6th decade. The origin of dizziness was classified as peripheral cause(25.3%), central cause(32.9%), and others(41.8%). As to nature of the dizziness, the rotatory sense was dominant in peripheral vertigo and the floating sense and blurred vision in central vertigo. Peripheral vertigo was triggered by position change of head and body, and central vertigo by the eye movement. Audiograms I showed that most patients with central vertigo had normal hearing, but 46.7% of thoswith peripheral vertigo had an abnormal hearing disturbance. Nystagmus was more prevalent in peripheral vertigo Conclusion: History taking and physical examination played an important role in the diagnosis of dizzy patients. An important part of the diagnosis of a dizzy patient could be to evaluate the peripheral origin, the central origin and others causes. Because central vertigo may be associated with a significant neurological pathology, spectral radiological studies, including MRI and CT, are mandatory to rule out a devastating brain lesion.
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조두신,신동운,박소정,배지은,감준범,박나연,김재성,오정수,신정원,조동형 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.8
Mitochondrial dynamics control mitochondrialmorphology and function, and aberrations in these areassociated with various neurodegenerative diseasesincluding Alzheimer’s disease and Parkinson’s disease. Toidentify novel regulators of mitochondrial dynamics, wescreened a phytochemical library and identified liquiritigeninas a potent inducer of mitochondrial fusion. Treatmentwith liquiritigenin induced an elongatedmitochondrial morphology in SK-N-MC cells. In addition,liquiritigenin rescued mitochondrial fragmentation inducedby knockout of mitochondrial fusion mediators such asMfn1, Mfn2, and Opa1. Furthermore, we found that treatmentwith liquiritigenin notably inhibited mitochondrialfragmentation and cytotoxicity induced by Ab in SK-NMCcells.
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계약제 교원인력의 운용 실태분석을 통한 정책과제의 탐색
신현석(Shin, Hyunseok),이경호(Lee, Kyoungho),정주영(Jung, Jooyoung),이정원(Lee, Jeongwon),우선영(Woo, Sunyoung),권소연(Kwon, Soyeon),양지운(Yang, Jiwoon),김진미(Kim, Jinmi),남소정(Nam, Sojung),이희영(Lee, Heeyoung),장나영(Jang, Nayou 고려대학교 교육문제연구소 2011 敎育問題硏究 Vol.0 No.40
학교에서 근무하는 교원들의 종류가 다양해지는 경향 속에 정규직이 아닌 계약제 교원인력이 날로 증가하는 추세에 있다. 본 연구는 정규직 교원을 중심으로 운영되는 학교조직에서 계약제 교원인력, 특히 기간제 교사와 강사의 운영 실태를 인적자원개발의 과정인 확보ㆍ활용ㆍ평가의 측면에서 분석하고 문제점을 도출하여 계약제 교원인력의 역량강화를 위한 정책과제를 탐색하는데 목적이 있다. 분석 결과 현행 계약제 교원인력인 기간제 교사와 강사를 학교에서 운용할 때, 채용과정에서의 공정성 확보 및 검증의 어려움 그리고 무계획성, 인력운용에 대한 관리 및 지도의 어려움과 체계적 연수의 부족, 공정한 성과관리 부족 등이 문제점으로 제기된다. 이러한 문제를 개선하기 위하여 공정한 채용방안 강구, 체계적 검증시스템 구축, 신분안정화 방안 강구, 체계적이고 지속적인 연수실시, 평가준거 및 기준의 확립, 교육수요자 만족도 조사 실시 등을 정책 과제로 제안한다. As the types of teacher working in school are getting diverse, the number of contracted teacher is increasing as well. The major purpose of the study is to derive the problems of contract teacher system, especially of term-based teacher and instructor, by analyzing it in terms of collection, management, and evaluation, and finally to explore policy measures. In the process of operating the current contract teacher, such as term-based teacher or instructor, there are some limitations as follows: difficulty in securing and ensuring the fairness of the employment process, lack in guiding personnel affairs and in providing systematic training, and absence in managing job performance. To improve these limitations, the study suggests to find ways for fair recruitment, to build systematic personnel management system, to secure stable status of contract teachers, to provide systematic and continued teacher training, to establish evaluative criteria and standards, and to conduct survey for exalting consumers’ satisfaction of education.
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