자연기흉의 양측 기포 동시제거술 : 11예 보고 11 CASES

오중환,윤양구,정경영,이두연,조범구,방서욱 대한의학협회 1990 대한의학협회지 Vol.33 No.2

심장보조를 위한 흉부대동맥 근성형술 개발(예비 동물실험)

오중환,박승일,김은기,김영호,류기홍,이상헌,원주호,서재정 대한흉부심장혈관외과학회 2000 Journal of Chest Surgery (J Chest Surg) Vol.33 No.6

Background: Thoracic aortomyoplasty is one of the surgical treatment for heart failure and has advantages over artificial heart or intraaortic balloon pumps. It uses autogenous skeletal muscles and solves problems such as energy source. However its use in clinical settings has been limited. This preliminary study was designed to develop surgical technique and to determine the effect of acute descending thoracic aortomyoplsty. Material and Method: Thirteen adult Mongrel dogs were used. The left latissimus dorsi muscle was wrapped around the descending aorta under general anesthesis. Swan-Ganz and microtipped Millar catheter were used for the hemodynamics and endocaridial viability ratio. Data were collected with myostimulator on and off in normal hearts and the ischemic hearts. Result: In normal hearts, the mean aortic diastolic pressure increased from 72$\pm$15mmHg at baseline to 78$\pm$13mmHg with stimulator on. Coronary perfusion pressure increased from 61$\pm$11mmHg to 65$\pm$9mmHg. Diastolic time increased from 0.288$\pm$0.003 msec to 0.290$\pm$0.003msec. Systolic time decreased from 0.164$\pm$0.002msec to 0.160$\pm$0.002 msec. Endocardial viability ratio increased from 1.21$\pm$0.22 to 1.40$\pm$0.18. In ischemic hearts, mean aortic diastolic pressure incrased from 56$\pm$21mmHg at baseline to 61$\pm$15mmHg with stimulator on. Coronary perfusion pressure increased from 48$\pm$17mmHg to 52$\pm$15mmHg. Diastolic time increased from 0.290$\pm$0.003 msec to 0.313$\pm$0.004msec. Systolic time decreased from 0.180$\pm$0.002 msec to 0.177$\pm$0.003 msec. Endovascular viability ratio increased from 0.9$\pm$0.31 to 1.1$\pm$0.31. The limited number of cases ruled out the statistic significance. Conclusion: Descending thoracic aortomyoplasty is a simple operation designed to use patient's own skeletal muscles. It trends to increase diastolic augmentation and coronary perfusion pressure. Modification of surgical technique and stimulator protocol would maximize the effect to assist the heart.

빈맥을 이용한 심부전 모델에서 회복궤도

오중환,박승일,원준호,김은기,이종국 대한흉부심장혈관외과학회 1999 Journal of Chest Surgery (J Chest Surg) Vol.32 No.5

배경: 빈맥을 이용하여 심부전을 만드는 방법은 확장성 심근증 모델 중에서 가장 좋은 방법으로 심장에 외과적 손상 혹은 약물의 독성을 최소화할 수 있고 사람의 심부전에 가장 가까우며 조작하기 쉬운 장점이 있다. 새로운 술식의 효과를 검증하기 위하여 심부전이 진행중인 모델에서 동물실험을 시행하는 것은 결과를 얻기 전에 실패할 가능성이 높다. 심부전의 진행을 중지시킨 회복궤도의 변화를 비교하는 방법은 심부전 악화에 의한 사망률을 줄일 수 있는 새로운 방법이지만 빈맥 조작 기술에 따라 저자마다 상당한 차이가 있어 이에대한 자료의 정립이 필요한 실정이다. 대상 및 방법: 21마리의 개(체중 25-35kg)를 대상으로 1)정상의 심장, 2) 심부전 심장, 3) 회복기 4주 4) 회복기 8주 등 4가지로 나누었다. 전신마취하에 우심실첨부에 박동기 전극을 삽입하여 빈맥은 처음 170회/분부터 매주 20회씩 프로그래머를 이용하여 증가시켰다. 4주 후 심부전이 발생하면 8주간의 회복기 동안 회복 궤도를 추적하였다. 심장의 크기와 혈역학적 변화를 관찰하고자 초음파는 2주마다, Swan-Ganz 도자와 열희석법은 4주마다 검사를 실시하여 이완기 말기 좌심실 체적, 수축기말기 좌심실 체적, 심박출율, 중심정맥압, 폐동맥압, 폐동맥 쐐기압, 우심실압, 일회박출량 등을 측정하였으며, 정상과 심부전 심장 상태에서 혈중 카테콜라민을 측정하였다. 그 외 심전도 및 대퇴동맥 도자를 넣어 맥박수, 혈압을 측정하였다. 정상심장, 심부전 심장, 회복기 4주 및 8주에서 측정한 값은 평균$\pm$표준편차로 표시하였다. 결과: 4마리(20%)가 심부전에 의한 합병증으로 사망하였다. 이완기 말기 좌심실 체적은 측정시기에 따라 40.8$\pm$7.4, 82.1$\pm$21.1, 59.9$\pm$7.7, 46.5$\pm$6.5ml로 수축기말기 좌심실 체적과 비슷한 변화양상을 보였으며 심박출율은 50.6$\pm$4.1, 17.5$\pm$5.8, 36.3$\pm$7.3, 41.5$\pm$2.4%였다. 혈압과 맥박은 의의 있는 양상을 보이지 않았으며 중심정맥압, 우심실압, 폐동맥압, 폐동맥 쐐기압 등은 심부전 시에 의의 있는 증가를 보이다가 회복기에는 감소하는 양상을 볼 수 있다. 일회박출량은 21.5$\pm$8.2, 12.3$\pm$3.5, 17.9$\pm$4.6, 15.5$\pm$3.4ml으로 회복기에 심부전 상태로부터 회복하는 경향을 볼 수 있었다. 혈중 카테콜라민은 정상 133.3$\pm$60.0pg/dL에서 심부전 시에는 479.4$\pm$327.3pg/dL로 증가를 보였다(p=0.008). 결론: 빈맥을 이용한 심부전 모델은 외과적손상이 적고, 병의 정도를 임의로 조절할 수 할 수 있는 간편한 방법이다. 회복기에는 심기능 및 심장비대가 회복하는 경향을 보이므로 향후 새로운 술식의 평가를 위하여 회복 궤도를 이용하는 경우 실험 동물의 심부전 악화에 의한 사망율을 줄일 수 있는 새로운 방법이다. Background: Tachycardia induced heart failure model would be the model of choice for the dilated cardiomyopathy. This more closely resembles the clinical syndrome and does not require major surgical trauma, myocardial ischemia and pharmacological or toxic depression of cardiac function. When heart failure is progressive, application of new surgical procedures to the faling heart is highly risky. It has been shown that recovery trajectory from heart failure is a new method in decreasing animal mortality. The purpose is to establish the control datas for recovery trajectory in the canine heart failure model. Material and Method: 21 mongrel dogs were studied at 4 stages(baseline, at the heart failure, 4 and 8 weeks after recovery). Heart failure was induced during 4 weeks of continuous rapid pacing using a pacemaker. Eight weeks of trajectory of recovery period was allowed. Indices of left ventricular function and dimension were measured every 2 weeks and the hemodynamics were measured by use of Swan-Ganz catheterization and thermodilution method every 4 weeks. Values were expressed as mean${\pm}$standard deviation. Result: 4(20%) dogs died due to heart failure. Left ventricular end-diastolic volume at the 4 stages were 40.8${\pm}$7.4, 82.1${\pm}$21.1, 59.9${\pm}$7.7 and 46.5${\pm}$6.5ml. Left ventricular end-systolic volume showed the same trend. Ejection fractions were 50.6${\pm}$4.1, 17.5${\pm}$5.8, 36.3${\pm}$7.3, and 41.5${\pm}$2.4%. Blood pressure and heart rate showed no significant changes. Pressures of central vein, right ventricle, pulmonary artery, and pulmonary capillary wedge showed significant increase during the heart failure period, normalizing at the end of recovery period. Stroke volumes were 21.5${\pm}$8.2, 12.3${\pm}$3.5, 17.9${\pm}$4.6, and 15.5${\pm}$3.4ml. Blood norepinephrine level was 133.3${\pm}$60.0pg/dL at the baseline and 479.4${\pm}$327.3pg/dL at the heart failure stage(p=0.008). Conclusion: Development of tachycardia induced heart failure model is of high priority due to ready availability and reasonable amenability to measurements. Recovery trajectory after cessation of tachycardia showed reduction of cardiac dilatation and heart function. Application of new surgical procedures during the recovery period could decrease animal mortality.

Asian Cultural Collectivism, Acculturation, and Life Satisfaction among Ethnic Asian Brides in South Korea

오중환,김현숙,이정희 숙명여자대학교 아시아여성연구원 2014 Asian Women Vol.30 No.3

The current study addresses the significance of cultural orientations for life satisfaction among marriage immigrants in South Korea. The subjects of our study have been selected from three ethnic groups of Asian brides living in Korea after their marriage with Korean men – Japanese, Chinese, and Vietnamese women. In this study, cultural orientations are classified into two parts: Asian cultural collectivism and acculturation to Korean society (openness to/liking of Korean culture and Korean language skills). Some other important predictors of life satisfaction are also included in the analysis. As the analytic strategy, this study employs the least-squares regression. One of our findings shows that the retention of Asian cultural collectivism contributes to ethnic Asian brides’ life satisfaction in Korean society. Likewise, there is evidence that their life satisfaction rises with their growing knowledge of and attachment to Korean cultural traditions and standards. Finally, their proficiency in the Korean language is also an important factor that exerts a positive effect on their life satisfaction in Korean society.

심근내 총상 파편 환자의 치험 1 례

오중환,원준호,박승일,서재정,황정주 대한외상학회 2000 大韓外傷學會誌 Vol.13 No.2

Gunshot injuries to the heart, lung and great vessels are rare, but gunshot injuries are increasing with increased use of guns in hunting. We experienced a patient whose heart had been injured in a hunting accident and report with literature reviews. A 43-year-old man was admitted to our hospital with gunshot wounds to the scalp, face, upper extremity, and anterior chest. Computed tomography and echocardiography revealed several pellets in the chest wall, epicardium, and myocardium of the right ventricle. The pellets in the chest wall and epicardium were removed by a left thoracotomy, but the pellet in the myocardium of the right ventricle was not removed. The patient was discharged from the hospital without any significant residual complications and has been followed up for 9 months after discharge.

요추궁 절제술 후 발생한 동정맥루

오중환 대한흉부심장혈관외과학회 1991 Journal of Chest Surgery (J Chest Surg) Vol.24 No.6

The formation of postlaminectomy arteriovenous fistula is unusual and the rongeur during discectomy with resultant simultaneous damage to artery and vein is causative. The delay in diagnosis is particularly distressing. The presence of a palpable abdominal thrill or bruit with or without congestive heart failure should results in a high index of suspicion of this entity. Prompt recognition and surgical closure of the post-laminectomy arteriovenous iliac fistula are most important in successful management.

임피던스를 이용한 체내수분 측정의 임상응용

오중환,윤형로,윤경봉 연세대학교 원주의과대학 1993 원주의대논문집 Vol.6 No.1

葉分析에 依한 몇가지 果樹들의 영양진단과 落葉 直前 3要素의 잎내 성분함량에 대한 硏究 (Ⅰ)

오중환 안성산업대학교 1976 論文集 Vol.7 No.-

葉分析에 依한 本校 果樹園 榮養診斷과 休眠期를 前後한 三要素의 잎내 含量으 變化量은 比較 檢討한 바 그 成績은 아래와 같았다. A : 사과의 N. P. K에 對하여 1. 사과잎중 질소의 變化量은 9月上旬이 2.7% 10月下旬이 2.4%로 落葉期를 前後하여 잎내 N질 함량이 漸減되었다. 2. 燐酸은 8月24日 0.24%에서 10月下旬에는 0.67%로 脫離層의 형성과 더불어 P의 老葉內 含量이 높았다. 3. 加里의 잎내 함량은 8月下旬이 3.9%에서 10月下旬에는 2.7%로 계속 감소했다. 4. 5回에 걸친 三要素平均値는 N : 2.60, P : 0.24, K : 3.30%이였고 三要素의 比率은 N : 4.20, P : 0.4, K : 5.4이었다. B : 포도잎의 N. P. K에 對하여 1. 질소질의 잎중 旬別含量變化는 8月下旬과 9月上旬이 2.6%였고 기타기간은 落葉期를 前後하여 잎내 질소함량이 10月下旬에 2.1%로 감소했다. 2. 旬別 포도 잎중 인산의 含量을 8月下旬과 10月上下旬이 각기 0.22%였고 기타 기간에는 0.20∼2.0%였다. 3. 포도잎중 가리의 함량은 1.2∼2.0%의 變化値는 N : 2.4, P : 0.21, K : 1.50%였고 그의 比率은 N : 5.82, P : 0.58, K : 3.63이였다. C : 밤잎의 N. P. K에 對하여 1. 질소의 잎중 含量變化는 2.4 ∼ 2.9%였고 9月下旬과 10月下旬의 잎중함량이 높았다. 2. 인산의 잎중 함량변화는 0.24 ∼ 0.44%였고 10月중 잎중함량이 8∼9月의 値에 比하여 높았다. 3. 가리의 잎중 함량변화는 0.64∼0.85%였고 10月 上旬値가 0.85%로 다른순에 比하여 함량이 많았다. 4. N. P. K의 平均含量은 N : 2.6, P : 0.36, K : 0.72%이고 N : P : K의 比率은 N 7.13 : P 0.91 : K 1.96이다. D : 자두잎의 N. P. K에 對하여 1. 질소의 平均含量은 2.4 ∼ 2.7%이고 8月下 ∼ 9月上旬이 2.6 ∼ 2.7%로 높았으나 10月下旬까지 계속 감소하여 2.4%에서 최하위치를 보였다. 2. 인산의 旬別平均含量은 0.21 ∼ 0.29%이였고 10月上旬의 잎중 인산함량은 0.29%로 다른 순별치보다 높았다. 3. 가리의 순별평균 함량은 2.60 ∼ 3.85%이고 落葉期에 近接함에 따라 漸減現狀이었다. 4. N. P. K의 平均含量은 N : 2.5, P : 0.24, K : 3.26%이고 3요소의 比率은 N 4.07 : P 0.60 : K 5.33이었다. E : 호두잎의 N. P. K에 對하여 1. 질소의 순별평균함량은 2.0 ∼ 2.7%이고 8月下旬부터 10月上旬까지 2.2 ∼ 2.7%를 유지하다가 10月下旬에는 2.0%로 감소했다. 2. 인산의 순별평균함량은 0.21 ∼ 0.33%이고 10月에 比較的 잎중인산함량이 높았다. 3. 가리의 순별평균함량은 1.24 ∼ 1.65%이고 9月下旬이 1.65%로 가장높은 함량을 보였고 8月下旬 1.55%를 기준으로 10月下旬에는 1.24%까지 감소했다. 4. N. P. K의 平均含量은 N 2.30 P 0.65 K 8.18%이고 3요소의 比率은 N 5.81 : P 0.69 : K 3.67이었다. This expriments is amied to find the daiagnosis nutrients and the behaiver or the nutrient condition by nitrogen phosphrous and potassium before the fruit tree dromant of the come deciduous fruit trees, at anserong unnior gricultural collage ochard. The nutrients ondition of apple trees leaves was an ajustment for fruit sets The Rates of N:P:K were 4.20:0.40:5.4. The nutrients state of grape vine and chestnut leaves were abnormal condition with a content of excesses nitrogen than P.K. Therefore, like a this condition of the grape and chestnut were a heavily blooming but a little fruit sets. The ratios of N:P:K were 5.82:0.58:3.63 in the grape leaves, 7.13:0.91:1.96 in the chstnut leaves. The nutrients condition of the blum leaves was a beasonable state but the walnut leaves had a slightly P and K. It's a bud condition of nutrient state of the walnut. The ates of N:P:K- were 4.07:0.60:5.33 in the plum leaves, 5.81:0.69:3.67 in the walnut leaves.

窒素水準이 배 품종一長十郎, 新高, 晩三吉 品種의 諸般生理現象에 미치는 影響

오중환 안성산업대학교 1983 論文集 Vol.15 No.-

1) N질의 시비량 增加에 따라 施肥量이 普肥區보다는 倍肥量區에서 收量增收 경향이 있었고 過肥區에서는 현저하게 增收性이 컸다. 2) N질의 시비량의 增加에 따라서 葉面積이 各 品種 共히 넓어졌다. 3) N질의 시비량에 따라 糖度는 過肥區가 普肥區나 倍肥區에 比하여 낮았음을 알 수 있었다. 4) Osmotic pressure를 species 별로 비교한 바 Nwlf 시비량이 증가함에 따라 삼투압이 증가하고 장십랑의 平均이 667.4인데 比하여 新高는 735.4였고 晩三吉은 732.2로 나타났다. 5) 內生的 Hormone의 Fructose와 Glucose 함량을 比較한 바 長十郞이 Fructose가 1.28mg이었고 Glucose가 17.12mg인데 比하여 新高와 晩三吉은 長十郞의 含量에 比하여 相當히 낮았다. 6) N施肥量에 따른 品種別 病葉數는 N施肥量이 증가 할수록 各品種 共히 증가되었고, 病葉數가 많았던 品種은 晩三吉이 가장 많았고 다음은 新高였고 아주 강한 耐病性의 品種은 長十郞 品種이었다. 7) 과수원 토양은 10cm와 20cm의 深層에서 채취하여 5요소를 分析한 바 20cm범위내에서 全窒素有機物, 燐酸, K가 많았고 Ca와 Mg는 表土에 가까운10cm 範位內에 含量이 많았다. 8) 窒素施肥量에 따른 品種別로 잎중의 질소함량을 N施肥量對時期別로 比較한 바 6월부터 8월말로 生育이 旺盛 할수록 N의 함량이 높았고 N施肥量이 증가됨에 따라 各 品種 共히 잎중 窒素의 농도가 높았다. 9) N시비량에 변화에 따라 인산의 葉中 농도를 6월부터 8월말에 걸쳐 조사한 바 成葉에 이름에 따라 品種 共히 P_2O_5의 量이 增加하였고 N過肥區의 P_2O_5의 量은 倍肥區에 比하여 葉中 함량이 낮았는데 이는 窒素와 燐酸間의 antagonism 現狀이라 생각 되었다. 10) N量의 倍加現狀에 따라 K_2O의 흡수량은 過肥區에서 잎중 함량이 감소 되었는데 이는 N : K의 拮抗作用 때문이라 推測 되었다. 11) N量의 倍加現狀에 따라 CaO와 Mgo의 일중 함량 변화는 成葉期에 이름에 따라 증가하는 경향이 顯著하고 過肥區에서 兩成分이 잎중 함량이 낮았는데 이는 N : Ca, N : Mg의 拮抗作用 때문이라 여겨진다. 1) Fallowing of the quantity of nitrogen, double nitrogen quantity fertilizer plot was increased yield comparison with normal nitrogen quantity, excessive nitrogen fertilizer plot was more increased yield than other treatment plot. 2) Leaves area were increased by increasing nitrogen fertilizer. 3) The quantity of nitrogen was increased, soluble solid (sugar content) was increased in normal nitrogen & double nitrogen fertilizer plot than excessive nitrogen fertilizer plot. 4) comparative with variety of osmotic pressure, the osmotic pressure was increased by increasing of nitrogen quantity, Singo's osmotic pressure was 735.4 & mansamgil variety osmotic pressure was 737.2 comparison with changsiprang's 667.4. 5) Comparative with quantitive of hormone of the fructose and Glucose, fructose of Changsiprang was 1.28mg, Glucose was 17.12mg but Singo and Mansamgil's glucose and fructose was more decreased than changsiprang. 6) Each variety of disease number of leaves were increased as increasing nitrogen quantitive fertilization, the most disease leaves was mansamgil variety than other varieties. 7) The analysis of ochard soil elements in depth from 10 to 20cm, total nitrogen organic matter P_2O_5 and K_2O were more encluded, Ca and Mg were more soil surface 10cm range area. 8) Each variety of nitrogen content in leaves by fertilizer were nitrogen quantitive fertilizer comparative with seasonal, nitrogen content was more higher by growth pear trees from June to the last of August. Fallowing of the nitrogen fertilizer increasing, each variety was more inculded nitrogen in leaves. 9) The observation of the P_2O_5 in leaves from June to August change the nitrogen fertilizer quantity, each variety was more inculded P_2O_5 as a old leaf, the double nitrogen fertilization plot's P_2O_5 element was lower in leaves than normal nitrogen fertilizer. It was think that between the nitrogen and phosphoric acid was antagonism. 10) As the phenomenon quantity of double nigrogen, observation a quantity of the K_2O was the lowest in leaf of excessive nitrogen plot. It was throught that there was antagonism between M:K fertilizer. 11) As the increasing the nitrogen fertilizer, the change of inculded of CaO and MgO were more increased in leaves as an old leaf, the excessive nitrogen plot was lower two elements in leaf. It was thought that there was antagonism in N:Ca, N:Mg.

배나무잎 검은점병의 발생원인 조사

오중환 안성산업대학교 1996 論文集 Vol.28 No.-

Symptom development of pear abnormal leaf spot was highest at the day/night temperature regimes of 23/18℃, and reduced remarkably at the higher and lower temperature regimes as 28/23℃ and 18/13℃. When the pear leaves were bagged or wrapped with various covering materials, little or no symptoms were developed. This was considered to be due to the masking effect of the symptom development induced by high temperatures as up to 46.8℃ after leaf covering. Chemical properties of soil samples from diseased and healthy trees did not show a consisent trend except phosphate whose content was higher in the soil from diseased trees. Simptom development was delayed when moisture levels in soil was over on below the optimum conditron, although the final disease severity did not differ greatly.