운동복지 프로그램 참여 노인여성의 HbA1c와 혈액 지질의 관계

오봉석 한국코칭능력개발원 2023 코칭능력개발지 Vol.25 No.5

기대수명 연장 및 노인인구 증가와 함께 당뇨병 노인 비율이 높아지고 있다. 본 연구의 목적은 노인여성들의 당화혈색소(HbA1c) 수준과 혈액 지질의 관계를 알아보는 데 있다. 이를 위해 운동복지 프로그램에 참여한 노인여성(74.54±5.14세) 384명을 HbA1c 수준에 기반하여 3개 집단으로 구분하였다. 즉, HbA1c〈 5.7%를 비당뇨병 집단(NDG, n=178), HbA1c 5.7~6.4%를 당뇨병 전단계 집단(PDG, n=158), HbA1c≥6.5%를 당뇨병 집단(DG, n=48)으로 구분하였다. 혈액 지질지표는 total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), non-HDL-C, TC/HDL-C, TG/HDL-C, non-HDL-C/TG 등 8 개였다. 연구변인들의 집단 차이를 알아보기 위해 분산분석법(ANOVA)을 적용하였고, 다중선형회귀분석(Multiple Linear Regression Analysis)을 통해 종속변수(HbA1c)와 독립변수(8개 지질지표)들 사이의 관계성을 파악하였다. 연구결과 NDG가 DG보다 TC, LDL-C, non-HDL-C, non-HDL-C/TG 수준에서 유의하게 높은 것으로 나타났다. 또한 TC는 약 200mg/dL 수준이고 LDL-C는 130mg/dL보다 약간 낮은 수준에 있는 노인여성들이 비당뇨병(HbA1c〈 5.7%)인 양상을 보였다. NDG에서는 non-HDL-C/TG가 HbA1c에 유의한 영향을주는 변수였고, non-HDL-C/TG 증가 시 HbA1c는 감소하는 관계성이 나타났다. PDG에서는 LDL-C가 HbA1c에 유의한 영향을 주는 변수였고, LDL-C 증가 시 HbA1c는 감소하는 것으로 나타났다. DG에서는 HDL-C가 HbA1c에 유의한 영향을 주는 변수였고, HDL-C 증가 시 HbA1c는 낮아지는 관계성이 나타났다. 이와 같은 결과는 노인여성들의 경우 혈액 TC는 200mg/dL, LDL-C는 130mg/dL보다 약간 낮은 수준일 때 비당뇨병일 가능성을 시사하고 있다. 또한 HbA1c가 당뇨병 수준인 노인여성들의 경우 HDL-C를 높이는 운동 및생활습관 중재는 HbA1c 수준을 낮추고 당뇨병을 관리하는 데 도움이 될 수 있음을 시사하고 있다. 이와 함께 노인의 TC 및 LDL-C가어느 정도 수준에서 높고 낮을 때 때 당뇨병 등 만성질환 및 수명에 긍정적 또는 부정적인 영향을 주는 지를 규명하기 위한 후속연구의 필요성이 제기되었다. The aim of this study was to investigate the relationship between glycated hemoglobin (HbA1c) levels and blood lipid profiles in elderly women in welfare exercise programs. The research subjects were 384 elderly women. The participants were divided into three groups based on HbA1c levels. Participants with HbA1c levels lower than 5.7% were classified as the non-diabetic group (NDG, n = 178). Subjects with HbA1c levels between 5.7% and 6.4% were categorized as the pre-diabetes group (PDG, n = 158). Subjects with HbA1c levels ≥ 6.5% were labeled as the diabetes group (DG, n = 48). Eight blood lipid indexes were analyzed, including total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), non-HDL-C, TC/HDL-C, TG/HDL-C, and non-HDL-C/TG. Differences in lipid profiles between the three groups were analyzed by one-way analysis of variance (ANOVA) with the Scheffe test. Relationships between the dependent variable (HbA1c) and independent variables (eight lipid indices) were analyzed by multiple linear regression analysis. The findings were as follows. The NDG group showed significantly higher levels of TC, LDL-C, non-HDL-C, and non-HDL-C/TG than the DG group. Elderly women with TC levels near 200 mg/dL and LDL-C levels of about 130 mg/dL showed non-diabetic HbA1c levels. There were no significant differences in TG, HDL-C, TC/HDL-C, or TG/HDL-C between the three groups. Non-HDL-C/TG in the NDG group was an independent variable with a significant effect on HbA1c levels. When the non-HDL-C/TG ratio in the NDG group increased by 1 point, HbA1c levels decreased by 0.083. LDL-C in the PDG group had a significant effect on HbA1c levels. When LDL-C in the PDG group increased by 1 point, the HbA1c level decreased by 0.001. HDL-C in the DG group was an independent variable with a significant impact on HbA1c levels. When HDL-C in the DG group increased by 1 point bigger, HbA1c levels decreased by 0.019. In summary, this study found that elderly women with somewhat high blood lipid profile levels, including TC (slightly lower than 200 mg/dL) and LDL-C (slightly lower than 130 mg/dL), could have non-diabetic blood glucose levels. In the DG group with HbA1c levels indicating diabetes, interventions for HDL-C level elevations through exercise and lifestyle changes are likely to have beneficial effects on improving HbA1c and diabetes. Further research is needed to investigate the evidence of the causality between diabetes, lifespan, and TC and LDL-C levels in elderly women.

Achalasia 의 외과적 치료

오봉석 대한흉부심장혈관외과학회 1982 Journal of Chest Surgery (J Chest Surg) Vol.15 No.4

For recently 2 years, 3 cases of esophageal achalasia were surgically treated by modified Heller operation with gastric fundoplication. Esophageal achalasia is functional disorder of lower esophagus of which symptoms are dysphasia, regurgitation, and weight loss. Preoperative diagnosis was made by clinical manifestations and radiologic examination, esophagoscopy and confirmed at operative table. Operative procedures are variable, but modified Heller operation is common method to handicap reflux esophagitis and postoperative esophageal stricture. Now, our patients who were surgically treated were well alive without complaining of specific symptoms for followed period.

냉혈 K 심정지액의 임상적 이용

오봉석,김상형,이동준,Oh, Bong-Suc,Kim, Sang-Hyung,Lee, Dong-Joon 대한흉부심장혈관외과학회 1982 Journal of Chest Surgery (J Chest Surg) Vol.15 No.1

Cold blood potassium cardioplegia, by two types of the infusion systems, was used in 45 patients who were undergone the open cardiac operation. Method A [in 25 patients] was the syringe infusion system and method B [in 20 patients] was the pump infusion system. Cold blood potassium cardioplegic solution was used less amount on method B than method A. Serum potassium was often increased significantly on method A as a result of excessive infusion of cold blood potassium cardioplegic solution. But method B, excessive infusion of cold blood potassium cardioplegic solution was prevented by reperfusion of the previous infused cold blood potassium cardioplegic solution through the recirculation system. Alteration of infused rate and concentration of potassium in cold blood potassium cardioplegic solution during infusion [which might be suggested on the method A] could be controlled on method B.

발육발달 요인과 인체구성 인자들의 관계를 통한 비만관련 트레이닝 적용법 제고

오봉석,윤신중 한국스포츠리서치 2005 한국 스포츠 리서치 Vol.16 No.1

외상성 횡경막손상의 외과적 고찰

오봉석,조완재,O, Bong-Seok,Jo, Wan-Jae 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.2

장거리달리기 생활체육 동호인의 10km 달리기 구간기록과 체중의 관계에 대한 사례연구

오봉석,조영제 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

폐동맥고혈압을 동반한 동맥관개존증의 장기관찰 성적

오봉석,조완재,이동준,O, Bong-Seok,Jo, Wan-Jae,Lee, Dong-Jun 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.5

This study concerns the late results observed at follow-up[average: 32.5 months] of 23 patients, in whom Patent Ductus Arteriosus with pulmonary hypertension among 55 patients. They were operated from May 1984 to July 1987 in Chonnam University Medical School. There was predominance of woman [2.5:1]. No operative death occurred. All of patients subside preoperative symptoms, but 1 patient diagnosed recannalization of duct at follow-up. Systolic murmur was found over the pulmonary area in 5 patients [22 %], but it may be not related to systolic pulmonary arterial pressure[SPAP]. Also, SPAP were normalized in 74 % of patients and had mild hypertension in 26 % of patients. Although the patients had Patent Ductus Arteriosus with pulmonary hypertension, successful surgical correction was carried out safely in all instance but one, by ligation and facilitated by hypotensive anesthesia.

Responses of m-GOT and humeral immune biomarkers to exhaustive endurance running and antioxidant supplementation in elite distance runners

오봉석 한국운동영양학회 2011 Physical Activity and Nutrition (Phys Act Nutr) Vol.15 No.1

This investigation examined the responses of mitochondrial aspartate aminotransferase (m-GOT) and immunoglobulins (IgA, IgG,IgM) to exhaustive endurance running and to antioxidants supplementation. Twelve female elite distance runners were divided into two groups (EG, CG) and participated in treadmill running test. EG was supplied with antioxidants for 12 weeks. Blood samples were collected before (Pre-test) and after (Post-test) 12 weeks at baseline (T1), exhaustion (T2), 30 minutes after exhaustion (T3) and 60 minutes after exhaustion (T4). m-GOT was not changed significantly, which suggested that the mitochondrial function of elite distance runners might not be hurt easily. There were significant differences of IgA, IgG and IgM within groups. In the Pre-test, EG and CG showed a significantly higher level in T2 than in T3. In the Post-test, EG didn't reveal such similarity but, compared to EG, CG showed a significantly higher level in T2 than in T3. These results suggest that antioxidant supplementation may have some beneficial effects on the humoral immune responses of elite distance runners. Correlation, factor- and regression-analysis showed that IgG has a significant relationship with all variables. These findings suggest that IgG may play important roles not only in maintaining of mitochodrial function but also in mediating immune responses.

간 부엽에 의해 심장압박이 동반된 선천성 횡격막 거상증

오봉석,송상윤,서홍주,임영혁,김보영 대한흉부심장혈관외과학회 2001 Journal of Chest Surgery (J Chest Surg) Vol.34 No.12

선천성 횡격막 거상증은 우측이나 좌측 또는 양측으로 발생할 수 있다고 알려져 있다. 횡격막의 중앙부위와 우측 중앙 건삭부위에서 간 부엽에 의해 심장압박이 동반된 선천성 횡격막 거상증 환자가 있어 비디오 흉강경을 통한 횡격막 주름 성형술을 시행하였던 증례를 보고하고자 한다. A case of congenital diaphragmatic eventration on the right and central tendinous portion with accessory hepatic lobe causing direct compression of the right heart is presented. We have performed the video assisted thoracoscopic plication of the right hemidiaphragm and eliminated the mass effect of the accessory hepatic lobe.

[우수작] 고양풍동지구 공동주택

오봉석 현대건축사 2001 월간 CONCEPT Vol.- No.31