차폐막을 이용한 치주조직 및 골조직 유도재생술의 실패요인에 대한 고찰

염혜리,구영,정종평,Yeom, Hey-Ri,Ku, Young,Chung, Chong-Pyoung 대한치주과학회 1997 Journal of Periodontal & Implant Science Vol.27 No.1

Using barrier membrane, guided bone regeneration(GBR) and guided tissue regeneration(GTR) of periodontal tissue are now widely studied and good results were reported. In bone regeneration, not all cases gained good results and in some cases using GTR, bone were less regenerated than that of control. The purpose of this study is to search for the method to improve the success rate of GBR and GTR by examination of the cause of the failure. For these study, rats and beagle dogs were used. In rat study, 5mm diameter round hole was made on parietal bone of the rat and 10mm diameter of bioresorbable membrane was placed on the bone defects and sutured. In 1 ,2, 4 weeks later, the rats were sacrificed and Masson-Trichrome staining was done and inspected under light microscope for guided bone regeneration. In dog study, $3{\times}4mm^2$ Grade III furcation defect was made at the 3rd and 1th premolar on mandible of 6 beagle dogs. The defects were covered by bioresorbable membrane extending 2-3mm from the defect margin. The membrane was sutured and buccal flap was covered the defect perfectly. In 2, 4. 8 weeks later. the animals were sacrificed and undecalcified specimens were made and stained by multiple staining method. In rats. there was much amount of new bone formation at 2 weeks. and in 4 weeks specimen, bony defect was perfectly dosed and plenty amount of new bone marrow was developed. In some cases, there were failures of guided bone regeneration. In beagle dogs, guided tissue regeneration was incomplete when the defect was collapsed by the membrane itself and when the rate of resorption was so rapid than expected. The cause of the failure in GBR and GTR procedure is that 1) the membrane was not tightly seal the bony defects. If the sealing was not perfect, fibrous connective tissue infiltrate into the defect and inhibit the new bone formation and regeneration. 2) the membrane was too tightly attached to the tissue and then there was no space to be regenerated. In conclusion, the requirements of the membrane for periodontal tissue and bone regeneration are the biocompatibility, degree of sealingness, malleability. space making and manipulation. In this animal study. space making for new bone and periodontal ligament, and sealing the space might be the most important point for successful accomplishment of GBR and GTR.

소아에서 급성 눈물샘염으로 발현된 비특이성안와염 1예

염혜리,강남여,Hae-ri Yum,Nam-Yeo Kang 대한안과학회 2011 대한안과학회지 Vol.52 No.11

Purpose: To report a case of idiopathic orbital inflammation presenting as unilateral acute dacryoadenitis in a child. Case Summary: A nine-year-old boy presented with painful swelling and redness in the right upper eyelid and temporal conjunctiva without systemic symptoms for five days. Acute orbital cellulitis was suspected but did not respond to systemic antibiotics. An orbital computed tomogram and magnetic resonance imaging revealed a diffusely enlarged and inflamed right lacrimal gland. The patient showed dramatic response to systemic corticosteroids, and acute dacryoadenitis due to idiopathic orbital inflammation was diagnosed. Treatment with oral corticosteroids for two months resolved the inflammation. No relapse was observed during four months of follow-up. Conclusions: Although rare, acute dacryoadenitis as a localized nonspecific orbital inflammation should be considered in the differential diagnosis of acute orbital cellulitis in pediatric patients. J Korean Ophthalmol Soc 2011;52(11):1357-1361

Identification of a Fibrillin-1 Gene Mutation in a Monozygotic Twin Presenting with Bilateral Juvenile- onset Ectopia Lentis

염혜리,김성은,신선영,박신혜 대한안과학회 2015 Korean Journal of Ophthalmology Vol.29 No.1

눈꺼풀 바닥편평세포암 1예

염혜리,조원경,백지선,양석우,Hae-Ri Yum,MD,Won-Kyung Cho,MD,Ji-Sun Paik,MD,Suk-Woo Yang,MD 대한안과학회 2011 대한안과학회지 Vol.52 No.12

Purpose: To report a rare case of basosquamous carcinoma of the eyelid, an aggressive tumor with a higher tendency for recurrence and metastasis. Case summary: An 87-year-old woman presented with a painful mass and bloody exudates at the left lateral lower eyelid. Four years previous, the patient was diagnosed with basosquamous carcinoma of the left lower eyelid after biopsy at another hospital. At that time, she was unable to receive operation because she had suffered from a serious heart condition. With time, the left lower eyelid mass continued to grow and symptoms and signs of pain and bloody exudates appeared. The patient underwent surgery for complete tumor resection and repair and the biopsy of a specimen showed tumor-free margins and no metastasis to distal sites. Conclusions: Basosquamous carcinoma is a subtype of basal cell carcinoma with aggressive behavior and a higher tendency for recurrence and metastasis. However, our case showed no recurrence with no metastasis to the nearby lymph nodes, vessels, or nerves. We report a case of basosquamous carcinoma of the eyelid at old age that was cured after operative resection. J Korean Ophthalmol Soc 2011;52(12):1519-1523

라식 후 백내장 수술을 받은 근시 환자의 술 후 굴절력의 장기 변화

염혜리,김만수,Hae Ri Yum,Man Soo Kim 대한안과학회 2012 대한안과학회지 Vol.53 No.12

Purpose: To evaluate the long-term change of postoperative refraction after cataract surgery in patients with a history of LASIK. Methods: A retrospective chart review was performed on 40 eyes of 28 patients who had undergone cataract surgery with a history of LASIK, and 40 eyes of 31 patients who had undergone cataract surgery without LASIK. We evaluated preoperative target refraction, and postoperative refraction during the 2-year follow-up period. Results: In the group with a history of LASIK, the target refraction was -1.00 ± 0.98 D, the 2-month postoperative spherical equivalent was -0.53 ± 1.92 D, and the 2-year postoperative spherical equivalent was -1.03 ± 1.84 D. In the group with cataract surgery only, the target refraction was -1.44 ± 1.06 D, the 2-month postoperative spherical equivalent was -1.07 ± 1.27 D, and the 2-year postoperative spherical equivalent was -0.97 ± 1.28 D. The difference in mean spherical equivalent at 2 months postoperatively and at 2 years postoperatively between the 2 groups was statistically significant (p = 0.037). The difference in mean spherical equivalent preoperatively and 2 years postoperatively between the 2 groups was statistically significant (p = 0.002). In the group with cataract surgery only, the postoperative refraction shifted to hyperopic refractive power, and was statistically significant. In the group with a history of LASIK, there were no statistically significant differences between preoperative and postoperative refraction. There were no statistically significant differences according to the cataract type in the group with a history of LASIK. The greater the myopic preoperative spherical equivalent was, the shorter the duration between LASIK and cataract surgery, which was significant in the group with a history of LASIK. Conclusions: The long-term refractive change after cataract surgery was statistically significant between the cataract surgery after LASIK group and the cataract surgery alone group.

Dental Implant Placement in an Edentulous Maxilla with Chronic Rhinosinusitis: A Case Report

염혜지,김성태,조영단 대한구강악안면임플란트학회 2022 대한구강악안면임프란트학회지 Vol.26 No.4

Implant surgery for an edentulous maxilla with severe resorption is challenging for clinicians, necessitating various preoperative considerations. This report demonstrates a case of implant placement for restoring an edentulous maxilla using guided bone regeneration and bilateral sinus lift surgery in a 47-year-old man with chronic rhinosinusitis. Prior to the surgical procedure, the patient had taken an antibiotic and a bronchodilator for 6 weeks after consulting with an otolaryngologist to minimize the risk of postoperative complications and implant failure. Seven implants were placed in the augmented maxillary anterior and posterior alveolar bones and were maintained without any complications. Meticulous preoperative evaluations increase the success rate of dental implantation, particularly in cases requiring invasive surgical procedures.

정원 박람회 출품작 분석을 통한 정원 유형 구분 연구

염혜리 ( Yum Hae Lee ),주신하 ( Joo Shin-ha ) 한국화예디자인학회 2017 한국화예디자인학 연구 Vol.36 No.-

2010년 경기정원문화박람회를 시작으로 서울정원박람회, 순천만국제정원박람회, 한평정원페스티벌, 코리아가든쇼 등 다양한 정원박람회의 개최가 증가하면서 일반인들에게도 정원박람회에 관한 사회적 관심이 증가하고 있다. 이렇듯 정원문화 확산을 통해 정원디자인의 개발과 소비가 이루어질 것으로 예상되며 정원 스타일의 유형화를 통해 소비자의 선호 취향에 따라 선택할 수 있는 직접적인 자료가 필요할 것으로 예상된다. 본 연구는 정원박람회 작품들을 대상으로 분석함으로써 정원박람회출품 구분틀을 제시하고 정원스타일 유형을 구분하는 것을 목적으로 한다. 최근 진행된 2014, 코리아가든쇼, 2015 서울정원박람회, 2015 경기정원박람회, 2016 코리아가든쇼에 출품된 20개의 작품들을 대상으로 14개 형용사쌍을 이용하여 118명에게 5점 척도로 설문조사를 시행하였다. 요인분석을 통해 정원스타일을 설명하는 4가지 요인인 현대-도시성, 쾌적성, 단순성, 사실성을 도출하였으며, 군집분석과 요인분석 결과를 통해 아티션 스타일, 캐주얼스타일, 한국적 스타일, 미니멀 스타일, 모던 스타일, 리빙가든 스타일 등으로 정원스타일을 구분하였다. 본 연구는 정원에 대한 일반인들의 반응을 기반으로 실증적인 방법을 이용하여 정원 스타일을 유형화한 연구로 그 의의가 있다고 할 수 있으며, 또한 작가 및 전문가의 의견뿐만 아니라 일반인 입장에서도 수용 가능한 커뮤니케이션 어휘를 도출하여 추후 세부적인 정원 분석틀로 연구에 활용될 수 있다는 의의가 있다. 반면 정원박람회 출품작만을 선별하여 분석하였기 때문에 본 연구 결과를 전체 정원에 적용하기에는 부족하다는 한계가 있다. Starting from Gyeonggi Garden Culture Expo in 2010, the increase of Garden Expo triggered the spread of garden culture to the public. It is expected that data for gardens should be selected according to consumer`s preference tastes through classification of garden styles. Firstly, this study aims to suggest communication vocabulary between designers and consumers as the increase of the social interest and demands for gardens. Secondly, this study suggests criteria for the classification of the garden expo entries, and lastly attempts categorizing garden styles. This study has done survey of 20 Korean Garden Expo Entries to 118 people using 14 adjective pairs. Factor analysis and cluster analysis were carried out to categorize gardens. From the factor analysis, 14 pairs of adjectives were helped to interpret the whole gardens by four componets `modernity-urbanity(현대-도시성)`, `amenity (쾌적성)`, `simplicity(단순성)`, `reality(사실성)`. Then, from both data of factor analysis and cluster analysis, gardens were categorized into 6 styles : Artisan Garden Style, Casual Garden Style, Korean Garden Style, Minimal Garden Style, Modern Style, Living Garden Style. The study has meaning of having done the research of using quantitative method on classification of garden styles, and the result can act as an acceptable communication vocabulary for both garden designers and consumers.

노인 1인가구를 위한 시니어 쉐어하우스 개발에 관한 연구

염혜실,권오정,Yeom, Hye-Shil,Kwon, Oh-Jung 한국주거학회 2014 한국주거학회 논문집 Vol.25 No.6

Proportion of senior population living alone in South Korea has exceeded over 20.2% in 2012, and it is anticipated that the proportion would increase every year. Poverty rate of seniors living alone in Korea is also anticipated to increase the highest rate (76.6%) among OECD countries. In particular, seniors lacking family support are having greater difficulty and isolated due to high housing costs and housing instability. Therefore, they need a new housing alternatives for considering their economical difficulty and lacking family and social support. This study attempted to examine possibility to develop a new housing alternatives for Korean seniors, especially living urban area. For this purpose, this study identified the attitudes and preference for a new house alternatives(Senior Shared House) by Korean seniors living alone. The key findings of this study were as follows: 1) Eighty-five percent of seniors participated in this study responded the senior shared house was needed. 2) It should be developed by utilizing or renovating and renting out existing housing in city areas. 3) Pre-residence checklist can be developed to connect and match prospect residents. 4) Professional workforce (e.g. housing welfare professional) is absolutely necessary to perform the role of coordinator understanding the various characteristics of the seniors, and their living requirements. Recommendations and directions for future development of senior shared house were suggested.

후박 및 은행엽 추출물을 함유한 치약의 임상 및 미생물학적 효과에 관한 연구

김태일,염혜리,류인철,배기환,정종평 충남대학교 약학대학 의약품개발연구소 1996 藥學論文集 Vol.12 No.-

Previous studies have shown that Magnoliae cortex and Ginkgo biloba extracts were showed on the antimicrobial and anti-inflammatory action, in vitro. The purpose of this study was to evaluate on the effect of antimicrobial and anti-inflammatory activity of Magnoliae cortex and Ginkgo biloba extracts containing dentifrice in gingivitis. 70 subjects with gingivitis were divided into an experimental group which performed normal oral hygiene procedure with Magnoliae cortex and Ginkgo biloba extracts containing dentifrice and a control group which also performed normal oral hygiene procedure with the same dentifrice without the natural extracts and completed a double-blind, cross-over study. At baseline and 3 weeks, subjects were assayed for clinical study by plaque index, gingival index, pocket depth, GCF rate, and microbiological study by subgingival dental plaque bacterial morphotypes by phase contrast microscopy, total anaerobes, total aerobes, Black pigmented bacteroides, A-actionomycetemcomitans, A.viscosus, C.rectus, S.sanguis, P.gingivalis, P.intermedia by bacterial culture and immunofluorescence microscopy. After 3 weeks using their respective dentifrices, reductions in the clinical indices of subjects were similar between the experimental dentifrice group and a control dentifrice group except for statistically significant much reductions in PI, GI, and GCF rate in the experimental dentifrice group as compared to control dentifrice group. Also statistically significant reductions in the motile rods and Spirochetes were found in both experimental group to compare with control group, however statistically much reduction in total anaerobes, Black pigmented bacteroides, and P.gingivalis, P.intermedia were found in the experimental dentifrice group as compared to control dentifrice group. This results indicates that Magnoliae cortex and Ginkgo biloba extracts containing dentifrice might be useful for elimination of gingival inflammation.

범발성 혈관내 응고증 환자에서 발현된 양안 망막중심정맥폐쇄 1예

정경인,염혜리,김인태,Kyoung In Jung,Hae Ri Yum,In Tae Kim 대한안과학회 2011 대한안과학회지 Vol.52 No.8

Purpose: To report a case of bilateral central retinal vein occlusion (CRVO) as one of the initial signs of disseminated intravascular coagulation (DIC). Case summary: A 33-year-old woman with a history of pregnancy-induced thrombotic thrombocytopenic purpura presented to our hospital with bilateral visual loss. On her initial visit, visual acuity was counting fingers at 30 cm in both eyes. Based on the findings of a funduscopic examination, the patient was diagnosed with bilateral CRVO. Laboratory tests confirmed the diagnosis of DIC combined with thrombotic thrombocytopenic purpura (TTP). Plasma exchange and transfusion of cryoprecipitate with fresh frozen plasma was performed. The ocular fundus findings did not improve. Despite medical treatment, the patient’s systemic condition deteriorated and she died of metabolic acidosis two weeks later. Conclusions: Bilateral central retinal vein occlusion occurred as a sign of aggravation of preexisting TTP and progression to DIC in the presented case. In patients with severe bilateral retinal venous changes, there should be a very high level of suspicion for presence or progression of systemic disease, with the possibility of effective early systemic evaluation and therapy. J Korean Ophthalmol Soc 2011;52(8):1005-1008