타액선종양의 임상적 고찰

양윤수(Yoon Soo Yang),김범규(Beom Kyu Kim),김연우(Yeon Woo Kim),권삼현(Sam Hyun Kwon),윤용주(Yong Joo Yoon),홍기환(Ki Hwan Hong) 대한두경부종양학회 2004 대한두경부 종양학회지 Vol.20 No.1

Background and Objectives: Salivary gland tumors are relatively rare and constitute 3% to 4% of all head and neck neoplasms. Their relative infrequency, inconsistent classification, and highly variable biologic behavior make some difficulty, but some general features can be drawn regarding the incidence, pathology, and pattern of behavior of the various benign and malignant tumors of salivary glands. The present study aims to provide a clinical characteristics of salivary gland tumors. Materials and Methods: We analyzed retrospectively clinical features of the 138 patients who were treated surgically at Chonbuk National University Hospital from 1992 through 2002. Results: We found 107 benign and 31 malignant tumors. Among the patients, 58 were males and 80 were females. The most common age group was the fifties. The most common site of both benign and malignant was parotid gland in major salivary glands and palatal region in minor salivary glands. The most common presenting symptom was palpable mass in both benign and malignant tumor. Histopathologically, the most common type was pleomorphic adenoma in benign tumor and mucoepidermoid carcinoma in malignant tumor. All cases were treated surgically and the most common postoperative complications was transient facial nerve weakness. Conclusion: 138 cases of salivary gland tumors were presented with respect to their clinical features.

성대용종의 중증도와 음향지수의 상관관계

홍기환,양윤수,김진성,이재근,이은정,Hong, Ki-Hwan,Yang, Yoon-Soo,Kim, Jin-Sung,Lee, Jae-Keun,Lee, Eun-Jung 대한후두음성언어의학회 2006 대한후두음성언어의학회지 Vol.17 No.1

Background and Objectives: Vocal polyp is the most common disease that causes hoarseness and its incidence is increased currently. The purposes of this study are to investigate the correlation between severity of vocal polyp and acoustic parameters and compare these data with those of the normal Korean. Materials and Methods: We analyzed the acoustic parameters of sustained vowel for 70 vocal polyp patients and 20 normal controls. A CSL(computerized speech lab) was used to carry out the analysis of the voice sample and statistical analysis was used Spearman correlation coefficient & t-test. Results: According to the conclusion of correlation analysis, 21 parameters of all the 34 parameters are significant. Conclusion: These data will be served as basic data for the evaluation of postoperative assessment of the patients with vocal polyp.

한국어 자음생성의 생리음성학적 특성

홍기환,양윤수,Hong, Ki-Hwan,Yang, Yoon-Soo 대한후두음성언어의학회 2006 대한후두음성언어의학회지 Vol.17 No.2

The stop consonants in Korean are classified into three types according to the manner of articulation as unaspirated (UA), slightly aspirated (SA) and heavily aspirated (HA) stops. Both the UA and the HA types are always voiceless in any environment. Generally, the voice onset time (VOT) could be measured spectrographically from release of consonant burst to onset of following vowel. The VOT of the UA type is within 20 msec of the burst, and about 40-50 msec in the SA and 50-70 msec in the HA. There have been many efforts to clarify properties that differentiate these manner categories. Umeda, et $al^{1)}$ studied that the fundamental frequency at voice onset after both the UA and HA consonants was higher than that for the SA consonants, and the voice onset times were longest in the HA followed by the SA and UA. Han, et $al^{2)}$ reported in their speech synthesis and perception studies that the SA and UA stops differed primarily in terms of a gradual versus a relatively rapid intensity build-up of the following vowel after the stop release. Lee, et $al^{3)}$ measured both the intraoral and subglottal air pressure that the subglottal pressure was higher for the HA stop than for the other two stops. They also compared the dynamic pattern of the subglottal pressure slope for the three categories and found that the HA stop showed the most rapid increase in subglottal pressure in the time period immediately before the stop release. $Kagaya^{4)}$ reported fiberscopic and acoustic studies of the Korean stops. He mentioned that the UA type may be characterized by a completely adducted state of the vocal folds, stiffened vocal folds and the abrupt decreasing of the stiffness near the voice onset, while the HA type may be characterized by an extensively abducted state of the vocal folds and a heightened subglottal pressure. On the other hand, none of these positive gestures are observed for the SA type. Hong, et $al^{5)}$ studied electromyographic activity of the thyroarytenoid and posterior cricoarytenoid (PCA) muscles during stop production. He reported a marked and early activation of the PCA muscle associated with a steep reactivation of the thyroarytenoid muscle before voice onset in the production of the HA consonants. For the production of the UA consonants, little or no activation of the PCA muscle and earliest and most marked reactivation of the thyroarytenoid muscle were characteristic. For the SA consonants, he reported a more moderate activation of the PCA muscle than for the UA consonant, and the least and the latest reactivation of the thyroarytenoid muscle. Hong, et $al^{6)}$ studied the observation of the vibratory movements of vocal fold edges in terms of laryngeal gestures according to the different types of stop consonants. The movements of vocal fold edges were evaluated using high speed digital images. EGG signals and acoustic waveforms were also evaluated and related to the vibratory movements of vocal fold edges during stop production.

편도적출술이 구강 및 비강 음향스팩트럼에 미치는 영향

최동일,공일승,이은정,소상수,양윤수,홍기환,Choi, Dong-Il,Kong, Il-Seung,Lee, Eun-Jung,So, Sang-Soo,Yang, Yoon-Soo,Hong, Ki-Hwan 대한후두음성언어의학회 2007 대한후두음성언어의학회지 Vol.18 No.1

Background and Objectives: It has been suggested that tonsillectomy possibly causes changes of voice because the morphology of the vocal tract is altered. This may cause serious problems for professional voice users. Materials and Method: Subjects were 26 patients. The oral and nasal sound spectrum of oral vowel /a/, /e/ and /i/ were measured before and after tonsillectomy. The formant frequencies and intensities for oral and nasal spectra were compared. The nasality and fundamental frequencies for oral vowel were measured. Results: The first formant frequencies for oral spectra of all vowels were not changed after surgery, but the second formant frequencies were increased significantly after surgery in the vowel /e/ and /i/. The first and second formant intensities for oral spectra were increased significantly after surgery in the all vowels. The first and second formant frequencies for nasal spectra of all vowels were not changed after surgery, but their intensities for nasal spectra were increased after surgery. The nasalities for oral vowel were not changed after surgery. Conclusion : Tonsillectomy appeared to change the spectral features of oral and nasal components of oral vowel, especially spectral intensities.

하인두암과 동반된 경부의 악성 말초 신경초종 1예

임상호(Sang Ho Lim),이경석(Kyung Seok Lee),양윤수(Yoon Soo Yang),홍기환(Ki Hwan Hong) 대한두경부종양학회 2012 대한두경부 종양학회지 Vol.28 No.1

The malignant peripheral nerve sheath tumor(MPNST) is an extremely rare soft tissue sarcoma of ectomes-enchyme also known as malignant schwannoma or malignant neurilemoma. It is a highly malignant sarcoma, which is locally invasive, frequently leading to multiple recurrences and eventual metastatic spread. The peak incidence of this disease is known to arise in the seventh decades. In human body, trunk and extremities are the most commonly involved sites, and only 8-14% of all lesions appear in head and neck region. Because immu-nohistochemical staining is essential in final diagnosis. The authors report a case of malignant peripheral nerve sheath tumor in neck with hypopharyngeal cancer simultaneously on a review of the literature.

경부 Castleman씨 병(거대 림프절 증식증) 1예

홍기환(Ki Hwan Hong),이상헌(Sang Heon Lee),양윤수(Yoon Soo Yang) 대한두경부종양학회 2004 대한두경부 종양학회지 Vol.20 No.2

Castleman's disease was first described from Benjamin Castleman in 1956. The disease today is enumerated among lymphoproliferative disorders and has unknown etiology. Although the mediastinum is a their most common location, they also occurs in other areas of the body, usually where lymph nodes are normally found. Castleman's disease of the neck is very rare. We describe a case of Castleman's disease of the neck in a middle aged man, and discuss the clinical presentation, radiological findings, and pathological features.

소음환경이 정상 및 병적음성에 미치는 영향

홍기환,양윤수,김현기 한국음성과학회 2002 음성과학 Vol.9 No.4

The purpose of this article is to present the acoustic parameters (VOT, jitter, shimmer, vF0, vAm, NHR, SPI, VTI, DVB, DSH) for consonants (/pipi/, /p^hip^hi/, /p'ip'i/) and sustained vowels (/a/, /e/, /i/) produced by normal subjects and dysphonia patients at two vocal effort(normal, high) by Lombard effect using 60dB white noise. Lombard effect indicates the vocal effort increase in noisy situation. At normal vocal effort, in general the acoustic parameter values of patients are greater than normal. And in noisy situation, significant decrease of acoustic values i seen in normal compared with in dysphonia paticents. Tfhe cflinical implication of this finding, the vocal quality in dysphonial is not compensated by vocal effort as well as normal subjects because of the inefficiency caused by abnormal vocal fold appearance and function. And with this result, we can counsel that the voice quality can not be improved as well as the patient expect.

음성장애에 대한 음향학적 중등도 지표

홍기환,김현기,양윤수 한국음성과학회 2003 음성과학 Vol.10 No.4

Background: The perceptual assessment is generally performed by the voice specialist. The objective evaluation is performed in a voice laboratory. Research in voice laboratories has generated a variety of different objective tests and parameters. The perceptual evaluation is one of the most controversial topics in voice research. Review of literature reveals a wide variety of rating scales and reliability data fluctuating from study to study. Unfortunately, there is no widely accepted valid method for classifying voice disorders and assessing outcome after voice treatment. Objectives: The goals of this research were to identify important objective acoustic parameters of vocal quality, and to establish an objective and quantitative correlate of the perceived vocal quality. Materials and Methods : We evaluated the voice analyzed data from 122 dysphonic patients and 20 normal volunteers. A computerized speech lab. 43OOB(CSL) was used to carry out the analysis of each voice sample. Results: Three dysphonia severity indices(DSI) were created using discriminant analysis. DSI is based on the weighted combination of the following selected set of acoustic parameters: absolute jitter(Jita in us), smoothed pitch period perturbation (sPPQ in %), amplitude perturbation quotient(APQ in %), soft phonation index(SPI), average fundamental frequency(Fo in Hz), lowest fundamental frequency(Flo in Hz), and smoothed amplitude perturbation quotient(sAPQ in %). The DSI, being the discriminating rule calculated by the logistic regression, consists of three equation based on statistically significant acoustic parameters. Three DSI were created to reflects best the degree of hoarseness as expressed by G from the GRBAS scale. The more positive this DSI is for a patient, the worse the vocal quality. The more it is negative, the better it is. The effect of sex is included implicitly in the DSI-l and DSI-2, so that a separate DSI-l and DSI-2 for males and females need not be used. The DSI is objective because no perceptual input is required for its calculation. Conculsion : This research demonstrates that the voice function values calculated from three different multivariate objective dysphonia severity indices are significantly associated with subjective voice assessments. These multivariate objective dysphonia severity indices may be appropriate for use in clinical trials and outcomes research on treatment effectiveness for voice disorders.