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급성 세균성 감염증에 대한 Cefotetan(Yamatetan^ⓡ)의 임상적 효과
김주옥,안원전,박종훈,노흥규,박종우 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1
Total 20 cases of infectious diseases were treated with Cefotetan at the Dept. of internal medicine, Chung Nam National University Hospital, Dae Jeon, Korea, from January 1985 to April 1985. Among 20 cases, 6 were the patients with acute pyelonephritis, 7 were pneumonia, 2 were acute cholecystitis, 2 were chronic bronchitis, 2 were cellulitis and 1 was lung abscess. The response was good in 16 cases, and poor in 4 cases. The laboratory tests were normal except I which was reversible. (mild elevation of SGOT and SGPT) The side effects were noted in 2 cases, such as skin eruption and drug fever, which were improved with supportive care. Cefotetan was thought to be useful against acute bacterial infections of respiratory, urinary, biliary tracts and cutaneous tissue.
박종훈,안원전 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2
Electrocardiograms obtained from 33 cases of oliguric phase of Korean Hcnorrhagic fever were analysed and serum potassium, calcium and phosphorous levels were measured also. The ECG tracings were abnormal in 25 cases. (75.8%) The abnormalities were sinus bradycardia, QT prologation, sinus tachycardia, non specific ST-T change and low voltage in the decreasing order of frequency. Sinus tachycardia was relatively high frequency compared with other studies. Total case of QT prolongation was 9 cases and among them 7 cases were associated with associated with significant hypocalcemia. We summerized that transient hemodynamic changes or electrolyte disturbance may be one of the causes of inns rate change or QT prolongation.
급성 일산화탄소중독 환자에서의 혈청 Myoglobin 치
노흥규,신영태,한현석,유철재,안원전 대한내과학회 1986 대한내과학회지 Vol.30 No.2
The serum myoglobin level was measured in 20 patients with acute Co poisoning and 20 healthy control subjects. The patients were classified into 3 groups based on clinical severity of intoxication. Group I included 7 casea with mild symptoms such as headache or exertional dyspnea, group II included 6 cases with moderate degree symptoms such as nauea, vomiting, dizziness, or drowsy mental state and group III included 7 cases with severe symptoms such as stuporous or comatous mental state, convulsion, or shallow respiration and heart rate. The results were as follows: 1) The mean value of serum myoglobin of 20 normal healthy persons was 19.6±0.27ng/ml. 2) The serum myoglobin was slightly increased in mild cases (30.4±4.02) compared to control groups. And in patients with moderate to severe symptoms was showed each significant increase compared with normal controls. The more severe symptoms of acute CO poisoning were presented, the more elevated level of serum myogloin. (moderate; 141.6±55.9, severe; 707.1±1) 3) There was significant relationship between elevated myoglobin and leukocytosis. Hypoxemia was noticed in 3cases with marked elevated level of serum myoglobin. 4) There was no significant relationship between serum myoglobin and BUN and creatinine.
노흥규,이헌영,유철재,안원전 대한핵의학회 1986 핵의학 분자영상 Vol.20 No.1
Subclinical hypothyroidism can be defined as an asymptomatic state in which a reduction in thyroid activity has been compensated by an increased TSH output to maintain a euthyroid state. We analysed clinical features, laboratory data, and pathologic findings in 39 cases of subclinical hypothyroidism who were diagnosed at the Dept. of Internal Medicine, Chungnam National University Hospital from Aug. 1984 to June, 1985. 1) The age distribution was from sixteen to sixty-nine and mean age was 34.8. Peak incidence was in the 4th decade and 3rd, 5th, 6th decade in order. 2) The sex distribution showed female preponderance with a ratio of 18.5 to 1. 3) The major presenting manifestations were nonspecific ones such as fatigue, indigestion, and anorexia. 4) Physical examination revealed diffuse goiter in 47.6%. Major abnormalities were no gross abnormality (30.9%), nodular goiter and facial edema. 5) There was no significant difference of the basal serum T3 and T4 concentrations between subclinical hypothyroidism and normal controls (p〉0.05). 6) The basal serum TSH concentration of subclinical hypothyroidism (32.61±14.95 μU/ml) was significantly higher than that of normal controls (3.92±1.05 μU/ml) (p〈0.005). 7) Microsomal antibody was detected in 80.6% and thyroglobulin antibody was detected in 30%. 8) The pathologic findings in 26 cases revealed Hashimoto's thyroiditis in 76.9% (lymphocytic type, 34.6%; oxyphilic type, 26.9%; fibrotic type, 15.4%). The others were adenomatous goiter (15.4%), adenomatous carcinoma (3.8%) and subacute thyroiditis (3.8%).