Effectiveness of the Hugging Balloon Technique in Coronary Angioplasty for a Heavy, Encircling, Calcified Coronary Lesion

안민수,윤정한,이준원,이경훈,김장영,유병수,이승환,최경훈 대한심장학회 2009 Korean Circulation Journal Vol.39 No.11

We report our experience in coronary angioplasty and intravascular ultrasonography (IVUS) on a heavy, encircling, calcified lesion that was not dilated with the use of a cutting balloon and a non-compliant balloon. The angioplasty was successfully performed with a simple and inexpensive hugging balloon technique. We report our experience in coronary angioplasty and intravascular ultrasonography (IVUS) on a heavy, encircling, calcified lesion that was not dilated with the use of a cutting balloon and a non-compliant balloon. The angioplasty was successfully performed with a simple and inexpensive hugging balloon technique.

공연과 연출 정신

안민수 동국대학교 연극영상학부 1999 演劇學報 Vol.27 No.-

Two Problems With Analyzing Natriuretic Peptide Levels: Obesity and Acute Myocardial Infarction

안민수,유병수 대한심장학회 2010 Korean Circulation Journal Vol.40 No.11

긴급차량 우선신호 시스템을 이용한 소방서와 병원 간의 연계방안 연구

안민수,김명수 한국도로학회 2020 한국도로학회 학술대회 발표논문 초록집 Vol.2020 No.09

저위험군의 불안정형 협심증 환자에서 B-Type Natriuretic Peptide와 장기 예후

안민수,유병수,이경훈,윤영진,김성윤,김장영,이승환,윤정한,최경훈 대한심장학회 2009 Korean Circulation Journal Vol.39 No.1

Background and Objectives: In acute coronary syndrome (ACS), the B-type natriuretic peptide (BNP) level is a strong predictor of mortality. Most ACS patients have a history of myocardial infarction (MI) or high risk ACS, clinical entities that are anticipated to lead to elevated BNP levels. Therefore, we assessed the relationship between BNP levels and long-term prognosis in low-risk patients with unstable angina (UA). Subjects and Methods: Between September 2002 and June 2004, BNP was measured in baseline samples from 137 patients referred for angiography. UA was defined as a clinical diagnosis paired with significant coronary artery narrowing. Patients had to exhibit no ST segment changes or abnormal Q waves, no elevation of cardiac enzymes, and no abnormal left ventricular diastolic or systolic function or regional wall motional abnormality on echocardiography. Major adverse cardiac events (MACEs) were defined as cardiovascular death, MI, or readmission due to heart failure. Results: The mean patient age was 62.2±10 years, and 70 (51.1%) of the patients were men. The mean follow-up duration was 44.5 months. Six patients died due to cardiac causes, 4 were admitted due to heart failure, and 2 had MIs. The mean BNP level was not different between patients suffering MACEs and those not suffering MACEs. Other characteristics were similar between the groups. Kaplan-Meier survival curves showed a statistically significant benefit in the BNP ≤80 pg/mL group (p=0.037). There were no significant prognostic factors on multivariate analysis. Conclusion: A single BNP measurement was not an independent prognostic factor, but was related to event-free survival in patients with low-risk UA. 요 약배경 및 목적급성 관동맥 증후군 환자의 예후를 예측하는 데 생화학적지표들이 유용한 것으로 알려져 있다. BNP는 급성 관동맥증후군에서 위험도를 계층화하고 장기 사망에 대한 강력한예후인자로서 유용성을 보고하고 있다. 하지만 저위험군의불안정형 협심증 환자에 대한 예후 인자로서 BNP의 중요성에 대한 보고는 아직 없었다. 이에 저위험군의 불안정형 협심증 환자에서 장기 예후 지표로서 내원시에 측정한 BNP의유용성을 평가하고자 하였다. 방 법2002년 9월부터 2004년 6월까지 허혈성 심질환으로 내원하여 관동맥 조영술을 시행 받고 50% 이상 협착이 동반된 환자 중 저위험군 불안정형 협심증 환자 139명을 대상으로 하여 주요 심장 사건 (심혈관 질환으로 인한 사망, 심근경색의 재발이나 심부전으로 인한 재입원)을 추적조사하였다. 불안정형 협심증은 ACC/AHA 치료 지침에 따른 불안정형 협심증 환자 중 관동맥 조영술상 50% 이상의 협착이 동반된 환자로 정의하였다. 저위험군의 정의는 심전도상 0.1 mV 이상의 ST 분절 하강이나 상승이 없고 비정상적인 Q파가 없으며, 심근 효소의 상승이 없는 환자로 정의하였다. 또한 심초음파상 좌심실 구혈률이 45% 미만이거나이완기 기능이 위정상 (pseudonormalized pattern), 제한형(restrictive filling)을 보인 환자와 신기능 장애를 가진 환자는 제외하였다. 결 과12명 (8.6%)의 환자에서 주요 심장 사건이 발생하였다. 주요 심장 사건이 발생한 군과 발생하지 않은 군 사이에 BNP 치에 통계적으로 유의한 차이는 없었으나 BNP치가 80 pg/ mL 초과군이 event free 생존율이 낮았다. 그러나 Cox proportional hazard regression 분석에서 주요 심장 사건의event free 생존율에 대한 독립적인 위험인자는 없었다. 결 론본 연구에서 내원시 측정한 BNP치는 저위험군 급성 관동맥 증후군 환자에서 주요 심장사건에 대한 독립적인 예후인자는 아니었지만 event free 생존율과 연관이 있었다.

연기양식에 있어서 정서와 외적 행동의 상호관계

안민수 한국연극학회 1985 한국연극학 Vol.2 No.1

위상 변환을 통한 특징 기반 메쉬 몰핑

안민수,이승용 한국컴퓨터그래픽스학회 2001 컴퓨터그래픽스학회논문지 Vol.7 No.4

Addition of N-terminal Pro-B-type Natriuretic Peptide Levels to Electrocardiography Criteria for Detection of Left Ventricular Hypertrophy: The ARIRANG Study

안민수,유병수,이지현,이준원,윤영진,안성균,김장영,이승환,윤정한,박종구,안성복,최은희 대한의학회 2015 Journal of Korean medical science Vol.30 No.4

The utility of electrocardiography (ECG) in screening for left ventricular hypertrophy (LVH)in general populations is limited mainly because its low sensitivity. B-type natriureticpeptide (BNP) is released due to the remodeling processes of LVH and could improve thediagnostic accuracy for the ECG criteria for LVH. We hypothesized that addition of BNPlevels to ECG criteria could aid LVH detection compared with ECG alone in a generalpopulation. We enrolled consecutive 343 subjects from a community-based cohort. LVHwas defined as LV mass index > 95 g/m2 for females and > 115 g/m2 for males accordingto echocardiography. The area under the receiver operator characteristic (ROC) curve todetect LVH was 0.55 (95% confidence interval [CI], 0.50-0.61) in Sokolow-Lyon criteriaand 0.53 (0.47-0.59) in the Cornell voltage criteria. After addition of N-terminal-proBNPlevels to the model, the corresponding areas under the ROC were 0.63 (0.58-0.69) and0.64 (0.59-0.69), respectively. P values for the comparison in areas under the ROC formodels with and without N-terminal-proBNP levels were < 0.001. These data suggest thataddition of N-terminal-proBNP levels to ECG criteria could significantly improve thediagnostic accuracy of LVH in general populations.

한국인 코호트에서 좌심실 비후를 진단하기 위한 심전도의 정확성

안민수,유병수,이지현,이준원,윤영진,안성균,김장영,이승환,윤정한,최경훈,고상백,안성복,박종구 대한고혈압학회 2013 Clinical Hypertension Vol.19 No.4

Background: Left ventricular hypertrophy (LVH) offers prognostic information beyond that provided by the evaluation oftraditional cardiovascular risk factors. However, the validation of electrocardiogram (ECG) criteria for the diagnosis of LVH islimited in Korea general population. The purpose of this study is to investigate the diagnostic accuracy of ECG criteria for thedetection of LVH in general population. Methods: In the present study, we investigated a total of 1,946 adults from thecommunity-based cohort. The left ventricular mass index (LVMI) was estimated with echocardiographic measurement andadjusted with body surface area. LVH was defined as a value greater than or equal to the sex-specific 90th percentile value ofLVMI. ECG criteria for the diagnosis of LVH were Sokolow-Lyon criteria and Cornell criteria. Results: The LVMI wassignificantly higher in male subjects (91.1 ± 23.9 g/m2 vs. 83.9 ± 21.7 g/m2, p <0.001). The cutoff values were 120.8 g/m2 in malesubjects and 112.2 g/m2 in female subjects. The sensitivity and specificity of Sokolow-Lyon criteria were 5.6% and 93.6% in male,4.1% and 97.8% in female. Those of Cornell criteria were 2.8% and 98.7% in male, 14.3% and 95.8% in female. In male, the areaunder the receiver operating characteristic curves of Sokolow-Lyon voltage and Cornell voltage were 0.55 and 0.52. And those infemale were 0.59 and 0.60. Conclusions: In our community-based sample, ECG criteria showed low sensitivity and high specificity. The performance of ECG criteria for detection of LVH was suboptimal, suggesting limited usefulness of ECG as mass screening tools.

Serial Monitoring of B-Type Natriuretic Peptide in Heart Failure Patients

안민수,유병수 대한심장학회 2007 Korean Circulation Journal Vol.37 No.9

The measurements of B-type natriuretic peptide (BNP) or N-terminal proBNP (NT-proBNP), when taken together with conventional clinical assessment, may assist in making the prognosis and also for making serial adjustment of such treatment. But although such commercial assays are currently approved for the diagnosis of heart failure, the role of the natriuretic peptides for monitoring the success of congestive heart failure (CHF) therapy has not as yet been submitted for regulatory approval. Moreover, because of the intra-individual biologic variation of the BNP or because of multiple factors that affect the BNP levels, the magnitude of the change of BNP levels must be large to confidently interpret BNP changes within an individual, and just how large has not been determined. Yet the levels of plasma BNP and NT-pro BNP are well correlated with the concurrent haemodynamic measurements and indicators of left ventricular systolic function. Also, BNP and NT-pro BNP serve as significant prognostic information and it is possible that adjustment of anti-heart failure therapy according to serial measurements of BNP (in addition to the standard clinical assessment) may offer improved outcomes. Better understanding of the test characteristics is needed before we can effectively use this valuable test to guide therapeutic strategies. (Korean Circulation J 2007;37:393-398)