http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 신헌섭 ( Heon Sub Shin ) (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
신헌섭 ( Heon Sub Shin ),이강진 ( Kang Jin Lee ),이태후 ( Tae Hoo Yi ) 한국두피ᆞ모발미용학회 2009 대한미용학회지 Vol.5 No.1
The hair cycle is divided 3 phases into anagen, catagen and telogen. Hair loss is the result of premature catagen caused by apoptotic signal. The process of apoptosis is controlled through the activation of many factors, such as inflammatory cytokines, p53, Bax and Bcl-2 family gene. Vitex rotundifolia has been used frequently as an indigenous medicine for curing headaches, colds, migraine, eye-pain, asthma, chronic bronchitis, and gastrointestinal infections. Recent studies have shown that the extracts from Vitex rotundifolia contain iridoids, flavonoids, and compounds with biochemical properties. In this study, C57BL/6 mice were treated topically on the depilated dorsal skin with Vitex rotundifolia extract dissolved in 70% EtOH. Moreover, treatment of Vitex rotundifolia extract onto hair cells induced more 20% growth of proliferation compared only control treated group. Also, the ratio of follicle number of anagen phase/total was increased. This result explains that Vitex rotundifolia extract has effect on prolong of anagen phase, so Vitex rotundifolia might be a potential new therapeutic source for the hair growth promotion.
-
C57BL/6 마우스 모델에서 웅지(곰기름)의 모발 성장 촉진 효과 연구
신헌섭 ( Heon Sub Shin ),박상용 ( Sang Yong Park ),이우철 ( Woo Cheol Lee ),신재호 ( Jae Ho Shin ),이태후 ( Tae Hoo Yi ) 대한미용학회(구 대한미용과학회) 2011 대한미용학회지 Vol.7 No.3
The hair cycle is into 3 phases including anagen, catagen and telogen. Hair loss is the result of premature catagen caused by apoptotic signal. The process of apoptosis is controlled through the activation of many factors, such as heredity, stress, aging and hormone. Selenarctos thibetanus (bear oil) has been used frequently as an indigenous medicine for moisture, freckle, cold, gray hair and dandruff. In this study, we investigate the effect of bear oil on hair growth in a depilated animal model of C57BL/6 mice. The animals were divided into 4 groups including negative control group (70% EtOH), positive control group (5% MXD), and experimental group (2%, 5% bear oil) and they were topically applied with an amount of 100 μL once a day for 2 weeks. Topical treatment of 5% bear oil for 2 weeks, hair follicles compared to the group to dorsal skin accelerated hair regrowth faster than 2% bear oil group, minoxidil group and 70% EtOH group. Also, hair density was increased The group treated with bear oil markedly increased the depth and size of the hair follicles in compare to the group treated by minoxidil and 70% EtOH. Also, more hair follicles assumed as in anagen were observed. This result explains that bear oil has effect on prolong of anagen phase, so bear oil might be a potential new therapeutic source for the hair growth promotion.
-
피부로 침투된 양자점 나노입자의 분포와 전자현미경 분석 시 발견되는 오스뮴산 결합물과의 구분
최기주,박상용,이정민,신헌섭,양정은,이돈길,이태후,Choi, Ki-Ju,Park, Sang-Yong,Lee, Jeong-Min,Shin, Heon-Sub,Yang, Jung-Eun,Lee, Don-Gil,Mavonov, Garfurjon T.,Yi, Tae-Hoo 한국현미경학회 2012 Applied microscopy Vol.42 No.1
나노입자의 가능성은 의생물학 분야의 연구자들에 의해 열띤 토론이 되어지고 있다. 우리는 일종의 추적자인 양자점(quantum dots)을 이용하여 피부로 침투된 나노입자의 분포를 전자현미경으로 확인하는 과정에서 나타나는 문제점과 이를 해결하기 위한 방법을 제안해 보고자 하였다. 나노입자는 피부의 각질층과 모공을 통한 일부 피지세포 내부까지 침투되는 것을 확인하였다. 이 과정에서 오스뮴산이 세포 내 지방산과의 결합에 의해 나노입자 형태의 축적물이 생성되는 것을 확인할 수 있었고, 이것은 의도한 나노입자(양자점)의 분포를 확인하는데 간섭을 주는 요인이 되는 문제점을 발견하였다. 이를 해결하기 위해, 양자점과 오스뮴산을 달리 처리하는 방법을 통하여 각각의 사진에서 나타나는 나노입자의 진위 여부를 비교하므로 의도한 나노입자의 정확한 분포를 확인할 수 있었다. 이러한 결과는 의생물 분야에서 생체내 나노입자의 분포를 확인하기 위한 연구 시 오차를 감소시키고, 보다 정확한 분석을 제공할 수 있을 것으로 기대해 본다. The possibility of nanoparticles (NPs) in biotechnology had been discussed by biomedical investigators. Here we report to suggest a solution and problems when using electron microscopy to determine the distribution of quantum dots (QDs) nanoparticles that penetrate skin. The results of this study showed that NPs were able to penetrate stratum corneum (SC) and sebocyte via hair follicle. However, we have found artifacts such as nanoparticles that are produced from combination of free fatty acid and osmium tetroxide during specimen preparation. It is usually difficult to identify NPs. Therefore, we tried to resolve these problems by comparing the cross-correlation image pattern that are derived from the images of sample that had been processed differently. This method can contribute to more accurate interpretation and minimal errors during the analysis using quantum dot as tracer.
-
보문 : 생물학적 전환에 의한 Compound K가 강화된 Ginsenoside의 HHDPC와 HaCaT 세포 증식 효과
박상헌 ( Sang Hun Park ),양정은 ( Jung Eun Yang ),신헌섭 ( Heon Sub Shin ),이정민 ( Jung Min Lee ) 대한미용학회(구 대한미용과학회) 2012 대한미용학회지 Vol.8 No.2
Ginsenosides have been regarded as the principal components responsible for the pharmacological and biological activities of ginseng. In this study, more than 100 strains of bacteria were isolated from 30 kinds of soil. The 32 strains of bacteria showing β-glucosidase activity were screened using a Esculin-R2A agar. In order to biotransformation of ginsenosides, β-glucosidase-positive bacteria were cultivated with protopanaxadiol (PPD) ginsenosides. Biotransformation of PPD into minor ginsenosides was confirmed by thin layer chromatography (TLC) 48 h after cultivation. THG 01 showing transformed minor ginsenosides in TLC was selected from soil and was revealed to belong to genus of Flavobacterium. Its crude enzyme could transform PPD into a mixture of minor ginsenosides (G-01), which contained compound K more than 50% in total ginsenosides in HPLC chromatogram. PPD treated at a concentration of 0.1μg/mL increased the proliferation of human hair dermal papilla (HHDPC) and human keratinocyte (HaCaT) cells by about 30%, compared with non-treated group. G-01 exerted more proliferative effect by about 50% than PPD. This result suggested that the mixture of minor ginsenosides and/or compound K formed by biotransformation may provokes the growth of hair by proliferative effect on HHDPC and HaCaT.
KCI
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
