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The Impact of the Aortic Pulse Wave Velocity on the Cardiovascular Outcomes of Hemodialysis Patients
신석준,임상현,박철휘,김영옥,송호철,김용수,최의진,김용균,정성진,정현화 대한의학회 2009 Journal of Korean medical science Vol.24 No.-
The aims of our study were to identify the risk factors for an increased aortic pulse wave velocity (AoPWV) and to assess the impact of the AoPWV on the cerebro-cardiovascular (CV) outcomes of hemodialysis (HD) patients. Seventy two HD patients were included, and the AoPWV, the echocardiography and the biochemical parameters were measured. After dividing the patients into tertiles according to the AoPWV values, we defined the low, the middle and the high AoPWV groups. The patients in the high AoPWV group showed a significantly higher age and high-sensitivity C-reactive protein level, a greater prevalence of diabetes and statin use, left ventricular hypertrophy, average pulse pressure (PP), AoPWV and left ventricular mass index and a lower serum albumin level than those in the low AoPWV group (p<0.05). On multivariate regression analysis of the AoPWV, age and the average PP were independently related to the AoPWV (p<0.05). On the multivariate Cox analysis for CV outcomes, the AoPWV and the average PP remained significant independent predictors of CV events. Our data suggest that an increased AoPWV is an independent predictor for the CV outcomes of HD patients.
지속성 외래 복막투석 환자에서 24시간 활동성 혈압과 혈장 Atrial Natriuretic Peptide 농도와의 연관성
신석준 ( Seok Joon Shin ),김병수 ( Byung Soo Kim ),김영옥 ( Young Ok Kim ),송호철 ( Ho Cheol Song ),이승헌 ( Seung Hun Lee ),김용수 ( Yong Soo Kim ),최의진 ( Eui Jin Choi ),장윤식 ( Yoon Sik Chang ),방병기 ( Byung Kee Bang ) 대한신장학회 2005 Kidney Research and Clinical Practice Vol.24 No.4