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RISS 인기검색어
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- 저자 : 송정엽 ( Jeong-yeop Song ) (검색결과 2 건)
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절제 불가능한 원발성 간세포암종에 대하여 DC beads(r)를 사용한 반복적인 경동맥 화학색전술 후 간절제술을 시행한 1예
송정엽 ( Jeong-yeop Song ),김영석 ( Young Seok Kim ),이재명 ( Jae Myeong Lee ),진수지 ( Soo Ji Jin ),최규성 ( Kyu Sung Choi,),이윤나 ( Yun Nah Lee ),김상균 ( Sang Gyune Kim ),정승원 ( Sung Won Jeong ),장재영 ( Jae Young Jang ) 대한간암학회 2013 대한간암학회지 Vol.13 No.1
In patients with unresectable hepatocellular carcinoma (HCC) and no anti-cancer treatment, the prognosis is quite poor. But in some cases, repeated sessions of transcatheter arterial chemoembolization (TACE) reduce the tumor size even to resectable, and post-TACE resection may prolong the survival time. We present a case of 50-year-old HBV carrier woman with abdominal distension. The diagnosis was huge HCC with intrahepatic metastasis. Repeated intra-arterial injections of adriamycin mixed lipiodol or DC beads(R) (100-300/300-500/500-700 μm, ⓒBIOCOMPATIBLES UK LTD) were instituted through ten sessions for 13 months. The tumor size became reduced with a partial response after 10th TACE and post-TACE resection was performed. No visible HCCs and decreased tumor markers were noted on the examinations 3 months after the resection.
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위장관 ; 미분화 조기위암에서 내시경 점막하박리술의 치료 성적
최문한 ( Moon Han Choi ),홍수진 ( Su Jin Hong ),한재필 ( Jae Pil Han ),송정엽 ( Jeong Yeop Song ),김대용 ( Dae Yong Kim ),서성우 ( Sung Woo Seo ),하지수 ( Ji Su Ha ),이윤나 ( Yun Nah Lee ),고봉민 ( Bong Min Ko ),이문성 ( Moon Sung 대한소화기학회 2013 대한소화기학회지 Vol.61 No.4
목적: 내시경 점막하박리술은 조기위암의 표준 치료로 받아들여지고 있다. 하지만, 미분화 조기위암에 대한 내시경 점막하박리술의 적응증은 아직 논란이 있다. 이번 연구에서는 확대 적응증에 의한 미분화 조기위암에서 내시경 점막하박리술의 치료 성적에 대해 파악하고자 하였다. 대상 및 방법: 순천향대학교 의과대학 부천병원에서 미분화 조기위암 환자 81명을 대상으로 82병변에 대해 내시경 점막 하박리술을 시행하였다. 치료 성적에 대해 절제 방법(일괄 절제, 분할 절제), 완전 절제율, 합병증, 재발률에 대해 조사하였다. 결과: 일괄 절제율과 완전 절제율은 각각 87.8% (72/82)과 80.5% (66/82)였다. 반지세포암종에서 저분화 선암종과 반지 세포를 동반한 저분화 선암종에 비해 높은 완전 절제율을 보였으나, 통계학적 의미는 없었다(89.3% vs. 75.0%, 76.7%; p=0.347). 저분화 선암종, 반지세포암종, 반지세포를 동반한 저분화 선암종에서 측면절제면 양성이 확인된 경우는 각각 12.5%, 3.6%, 13.3%였다(p=0.395). 기저절제면 양성이 확인된 경우는 각각 12.5%, 3.6%, 10.0%였다(p=0.485). 평균 37.4 개월의 추적기간 동안 재발률은 3.0%였다. 결론: 확대 적응증에 의한 미분화 조기위암에서의 내시경 점막하박리술은 유용한 치료가 될 것으로 생각되나, 장기적이고 대규모의 연구가 필요하겠다. Background/Aims: Endoscopic submucosal dissection (ESD) has been accepted as a standard treatment of early gastric cancer (EGC). However, the indication of ESD in undifferentiated-type EGC was controversial. The aim of this study was to evaluate the therapeutic outcomes of ESD in undifferentiated-type EGC according to expanded indication. Methods: At Soonchunhyang University Bucheon Hospital, a total of 82 lesions in 81 patients with undifferentiated-type EGC were treated with ESD. The therapeutic outcomes of ESD were evaluated by resection method (en bloc resection; piecemeal resection), histologic curative resection, complications and recurrence rates after ESD. Results: The rate on en bloc resection and complete resection rate were 87.8% (72/82) and 80.5% (66/82), respectively. In signet ring cell carcinoma, the complete resection rate was higher than those in poorly differentiated adenocarcinoma and poorly differentiated adenocarcinoma with signet ring cell features, but there was no statistical significance (89.3% vs. 75.0%, 76.7%; p=0.347). The lateral margin positivity rate in poorly differentiated adenocarcinoma, signet ring cell carcinoma and poorly differentiated adenocarcinoma with signet ring cell features were 12.5%, 3.6% and 13.3%, respectively (p=0.395). The vertical margin positivity rate were 12.5%, 3.6% and 10.0%, respectively (p=0.485). The overall recurrence rate was 3.0% during a mean follow-up period of 37.4 months. Conclusions: ESD may be considered as a feasible treatment for undifferentiated-type EGC according to expanded indication. The therapeutic outcome of ESD in undifferentiated-type EGC is likely to be favorable, though further longer follow-up studies are needed. (Korean J Gastroenterol 2013;61:196-202)
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